iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Xtr-131789

Ensembl Protein ID

ENSXETP00000006638.2

UniProt Accession

F7DMB9; F7DMB9_XENTR

Genbank Protein ID

ENSXETP00000006638

Protein Name

WD repeat domain 62

Genbank Nucleotide ID

AAMC01109065

Gene Name

wdr62

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSXETG00000003043.3	ENSXETT00000006638.2	ENSXETP00000006638.2

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	1.90e-34	116.4	94	127
UBD/Beta-Prp	2.80e-58	197.6	421	599

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 1    gHtdsvtclaf.sd.tllvsGs..dDgtikvWDl 30
           gH+ +v+c++f +d +++vs +  +D +i vWD+
   Q: 94   GHKYGVSCVCFsPDmKYVVSVGyqHDMVINVWDW 127
           8***********999*******9**********7 PP

UBD/Beta-Prp

   S: 45   lrslsgheaevtavkfspdgkilvtgseDrtikvwdlstgkcvhtlkghedsvlslsfsp..sg.dklvsGshdrtirvwdletgqcle 130
            + + + +++++ +k+ pdg+ l++g + ++i+++dl  ++ + t+++h+ +vl+l++s+  +g   l+s+s+dr i+v + e+++ le
   Q: 421  KSDVRDTKSGIRVLKIRPDGQHLASGDRTGNIRIYDLGIFDELLTIEAHDGEVLCLEYSKpsTGvTLLASASRDRLIHVLNAEKDYILE 509
           4566788899**************************************************9878999********************** PP
   S: 131  etlsghdgvvncvvvhpdg..nllvsGslDrtvrlWdl........ktgkllrtltgghtdsvyslsfdsngkelvsgsldgtvklwdl 209
           +tl+ h+++++ v++ +d+   l++s+++D+ +  ++          + +l +t +   + + y +++d ++k ++ + +d+ ++l+++
   Q: 510  QTLDDHSSSITAVKFAGDQeeILMISCGADKSIY-FRPaqmlpdgiHFSRLHHTVE---KTAMYDMDVDVSQKTVAVACQDKNIRLYSI 594
           ***************9988757899********9.766788888888888888885...599*************************** PP
   S: 210  qtgec 214
           ++g+ 
   Q: 595  SSGKQ 599
           *9985 PP

Organism

Xenopus tropicalis

Protein Sequence
(Fasta)

VELEKVLGIT VSSNSSITCD PISGLIAYPA GCVIVVLCPR KNKQTHIFNT CRKPLSALSF 60
SPNGKFIVTG ESGHNPAVRI WDVAEKVLVS EMLGHKYGVS CVCFSPDMKY VVSVGYQHDM 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GTGGAACTGG AAAAAGTTTT GGGAATTACA GTATCCAGCA ACAGCAGTAT TACTTGTGAC 60
CCTATTTCTG GACTTATTGC CTATCCTGCT GGGTAAGATA ATAGGTAGAT TTTTTTTCAG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0677--Repeat
KW-0853--WD repeat

Interpro

IPR011047--Quinoprotein_ADH-like_supfam
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR017986--WD40_repeat_dom

PROSITE

PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF00400--WD40

SMART

SM00320--WD40

Gene Ontology

GO:0071013--C:catalytic step 2 spliceosome
GO:0071011--C:precatalytic spliceosome
GO:0005682--C:U5 snRNP
GO:0008380--P:RNA splicing

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001371	Ailuropoda melanoleuca	59.51	0.00e+00	997.00
IUUC-Afu-008757	Aspergillus fumigatus	21.77	2.00e-25	111.00
IUUC-Bgr-012083	Blumeria graminis	22.64	1.00e-22	102.00
IUUC-Bta-013336	Bos taurus	59.76	0.00e+00	1013.00
IUUC-Cja-019094	Callithrix jacchus	59.51	0.00e+00	987.00
IUUC-Cfa-020529	Canis familiaris	59.51	0.00e+00	1003.00
IUUC-Cpo-021970	Cavia porcellus	59.04	0.00e+00	972.00
IUUC-Cre-022999	Chlamydomonas reinhardtii	27.88	6.00e-16	79.30
IUUC-Csa-024161	Chlorocebus sabaeus	59.39	0.00e+00	976.00
IUUC-Cho-024310	Choloepus hoffmanni	58.17	4.00e-174	605.00
IUUC-Cgl-026454	Colletotrichum gloeosporioides	21.79	1.00e-20	95.50
IUUC-Dor-031147	Dipodomys ordii	57.00	0.00e+00	940.00
IUUC-Dse-031501	Dothistroma septosporum	23.10	4.00e-26	113.00
IUUC-Eca-033675	Equus caballus	59.05	0.00e+00	997.00
IUUC-Fca-035826	Felis catus	59.39	0.00e+00	993.00
IUUC-Fox-037952	Fusarium oxysporum	21.99	2.00e-23	104.00
IUUC-Ggo-045152	Gorilla gorilla	60.00	0.00e+00	994.00
IUUC-Hsa-045891	Homo sapiens	59.88	0.00e+00	987.00
IUUC-Itr-048019	Ictidomys tridecemlineatus	60.91	0.00e+00	996.00
IUUC-Laf-053992	Loxodonta africana	58.97	0.00e+00	999.00
IUUC-Mcc-054994	Macaca mulatta	60.00	0.00e+00	993.00
IUUC-Meu-056815	Macropus eugenii	56.79	0.00e+00	917.00
IUUC-Mtr-058383	Medicago truncatula	31.07	2.00e-51	196.00
IUUC-Mmr-060693	Microcebus murinus	59.76	0.00e+00	1011.00
IUUC-Mdo-063007	Monodelphis domestica	60.47	0.00e+00	1016.00
IUUC-Mmu-064067	Mus musculus	59.41	0.00e+00	995.00
IUUC-Mpu-066532	Mustela putorius furo	60.12	0.00e+00	1015.00
IUUC-Mlu-066982	Myotis lucifugus	59.39	0.00e+00	990.00
IUUC-Nle-070042	Nomascus leucogenys	59.39	0.00e+00	978.00
IUUC-Opr-070397	Ochotona princeps	59.34	0.00e+00	996.00
IUUC-Ocu-074274	Oryctolagus cuniculus	59.73	0.00e+00	992.00
IUUC-Oga-088577	Otolemur garnettii	59.25	0.00e+00	991.00
IUUC-Oar-090117	Ovis aries	56.58	0.00e+00	943.00
IUUC-Ptr-090553	Pan troglodytes	59.76	0.00e+00	989.00
IUUC-Pab-098510	Pongo abelii	59.88	0.00e+00	994.00
IUUC-Pva-102895	Pteropus vampyrus	59.76	0.00e+00	1008.00
IUUC-Rno-105598	Rattus norvegicus	58.90	0.00e+00	994.00
IUUC-Sha-107013	Sarcophilus harrisii	60.78	0.00e+00	1016.00
IUUC-Sar-113261	Sorex araneus	59.54	0.00e+00	999.00
IUUC-Ssc-115317	Sus scrofa	59.22	0.00e+00	1003.00
IUUC-Tsy-118799	Tarsius syrichta	61.05	4.00e-170	592.00
IUUC-Tme-127128	Tuber melanosporum	22.83	4.00e-29	123.00
IUUC-Ttr-128722	Tursiops truncatus	56.10	0.00e+00	929.00
IUUC-Vpa-130392	Vicugna pacos	67.92	1.00e-61	231.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence