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Tag Content
iUUCD ID IUUC-Oga-087935
Ensembl Protein ID ENSOGAP00000013506.2
UniProt Accession H0XCI5; H0XCI5_OTOGA
Genbank Protein ID ENSOGAP00000013506
Protein Name Protein HIRA
Genbank Nucleotide ID AAQR03174493
Gene Name HIRA
Ensembl Information
Ensembl Gene ID Ensembl Transcript ID Ensembl Protein ID
ENSOGAG00000015079.2 ENSOGAT00000015089.2 ENSOGAP00000013506.2
Status Unreviewed
Classification
Family E-Value Score Start End
E3 adaptor/Cullin RING/DCX/DWD 4.60e-20 70.9 69 98
Active Site
Position(s) Description Evidence
N/A N/A N/A
Domain Profile

   E3 adaptor/Cullin RING/DCX/DWD
   S: 2    Htdsvtclaf.sd.tllvsGsdDgtikvWD 29
           H + v+c+++ ++  +l+sG+dD+ i+vW 
   Q: 69   HLACVNCVRWsNSgMYLASGGDDKLIMVWK 98
           8899******955699*************7 PP
   
Organism Otolemur garnettii
Functional Description
(View)

Functional Description


     Required for replication-independent chromatin assembly and for the periodic repression of histone gene transcription during the cell cycle.
 Required for replication-independent chromatin assembly and for the periodic repression of histone gene transcription during the cell cycle.
Protein Sequence
(Fasta)
AKLDVVCFFS FLGKPIFSVD IHPDGTKFAT GGQGQDSGKV VIWNMSPVLQ EDDEKDENIP 60
KMLCQMDNHL ACVNCVRWSN SGMYLASGGD DKLIMVWKRA TYIGPSTVFG SSGKLANVEQ 120
It may take some time, please wait.

Protein Fasta Sequence


>IUUC-Oga-087935|E3,WD_repeat|Otolemur garnettii
Please wait for a moment...
Nucleotide Sequence
(Fasta)
GCCAAATTAG ATGTTGTATG TTTTTTTTCG TTTCTAGGCA AGCCAATTTT TTCAGTTGAT 60
ATTCACCCTG ACGGGACCAA GTTCGCAACT GGAGGACAAG GTATGTTTAT GAAGTAAGGA 120
It may take some time, please wait.

Nucleotide Fasta Sequence


>IUUC-Oga-087935|E3,WD_repeat|Otolemur garnettii
Please wait for a moment...
Sequence Source Ensembl
Keyword

KW-0156--Chromatin regulator
KW-0181--Complete proteome
KW-0539--Nucleus
KW-1185--Reference proteome
KW-0677--Repeat
KW-0678--Repressor
KW-0804--Transcription
KW-0805--Transcription regulation
KW-0853--WD repeat
Interpro

IPR031120--HIR1
IPR011494--Hira
IPR019015--HIRA_B_motif
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom
PROSITE

PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION
Pfam

PF07569--Hira
PF09453--HIRA_B
PF00400--WD40
SMART

SM00320--WD40
Gene Ontology

GO:0070062--C:extracellular exosome
GO:0000790--C:nuclear chromatin
GO:0043234--C:protein complex
GO:0016569--P:covalent chromatin modification
GO:0006336--P:DNA replication-independent nucleosome assembly
GO:0007369--P:gastrulation
GO:0042692--P:muscle cell differentiation
GO:0001649--P:osteoblast differentiation
GO:0006355--P:regulation of transcription, DNA-templated
GO:0006351--P:transcription, DNA-templated
Orthology
iUUCD ID Species Identity E-value Score
IUUC-Ata-001039 Aegilops tauschii 35.05 8.00e-86 311.00
IUUC-Aml-001723 Ailuropoda melanoleuca 95.54 0.00e+00 1754.00
IUUC-Atr-003132 Amborella trichopoda 36.40 3.00e-85 310.00
IUUC-Apl-003197 Anas platyrhynchos 84.63 0.00e+00 1608.00
IUUC-Aca-004733 Anolis carolinensis 82.79 0.00e+00 1562.00
IUUC-Aly-005446 Arabidopsis lyrata 40.05 3.00e-78 286.00
IUUC-Ath-007627 Arabidopsis thaliana 41.30 2.00e-81 297.00
IUUC-Ago-007766 Ashbya gossypii 29.95 5.00e-57 216.00
IUUC-Acl-008104 Aspergillus clavatus 29.25 4.00e-61 229.00
IUUC-Afl-008591 Aspergillus flavus 30.50 8.00e-61 229.00
IUUC-Afu-008781 Aspergillus fumigatus 30.42 2.00e-58 220.00
IUUC-Ani-009272 Aspergillus nidulans 31.28 1.00e-54 208.00
IUUC-Ang-009655 Aspergillus niger 30.37 2.00e-61 231.00
IUUC-Aor-010119 Aspergillus oryzae 30.50 2.00e-61 231.00
IUUC-Ate-010530 Aspergillus terreus 31.28 3.00e-53 203.00
IUUC-Ame-011147 Astyanax mexicanus 85.23 8.00e-46 174.00
IUUC-Bgr-012237 Blumeria graminis 33.33 2.00e-58 221.00
IUUC-Bta-013320 Bos taurus 90.14 0.00e+00 1748.00
IUUC-Bci-013795 Botrytis cinerea 29.36 7.00e-64 239.00
IUUC-Bdi-014075 Brachypodium distachyon 42.45 5.00e-88 319.00
IUUC-Bol-016440 Brassica oleracea 34.91 1.00e-84 308.00
IUUC-Bra-016651 Brassica rapa 40.31 9.00e-84 305.00
IUUC-Cel-018692 Caenorhabditis elegans 38.04 2.00e-73 270.00
IUUC-Cja-018987 Callithrix jacchus 96.72 0.00e+00 1712.00
IUUC-Cfa-020132 Canis familiaris 95.17 0.00e+00 1757.00
IUUC-Cpo-021484 Cavia porcellus 95.83 0.00e+00 1765.00
IUUC-Cre-022846 Chlamydomonas reinhardtii 36.00 2.00e-59 224.00
IUUC-Csa-023081 Chlorocebus sabaeus 96.83 0.00e+00 1773.00
IUUC-Cin-025182 Ciona intestinalis 55.91 9.00e-151 528.00
IUUC-Csv-026154 Ciona savignyi 55.49 2.00e-147 516.00
IUUC-Cgl-026655 Colletotrichum gloeosporioides 30.91 1.00e-61 231.00
IUUC-Cne-026891 Cryptococcus neoformans 41.55 3.00e-80 293.00
IUUC-Cme-027349 Cyanidioschyzon merolae 29.18 6.00e-53 202.00
IUUC-Dre-027655 Danio rerio 68.24 0.00e+00 1312.00
IUUC-Dno-029557 Dasypus novemcinctus 84.08 0.00e+00 1098.00
IUUC-Dor-030687 Dipodomys ordii 86.56 0.00e+00 730.00
IUUC-Dse-031334 Dothistroma septosporum 30.89 1.00e-59 224.00
IUUC-Dme-031746 Drosophila melanogaster 55.43 6.00e-153 535.00
IUUC-Ete-032384 Echinops telfairi 88.18 0.00e+00 1617.00
IUUC-Eca-033430 Equus caballus 95.24 0.00e+00 1735.00
IUUC-Fca-036121 Felis catus 94.59 0.00e+00 1753.00
IUUC-Fal-036817 Ficedula albicollis 84.02 0.00e+00 1611.00
IUUC-Fox-037906 Fusarium oxysporum 35.09 1.00e-65 244.00
IUUC-Fso-038409 Fusarium solani 33.83 8.00e-64 239.00
IUUC-Gmo-039151 Gadus morhua 85.71 0.00e+00 681.00
IUUC-Ggr-040016 Gaeumannomyces graminis 35.20 2.00e-66 247.00
IUUC-Gga-040936 Gallus gallus 84.83 0.00e+00 1668.00
IUUC-Gac-041405 Gasterosteus aculeatus 62.63 0.00e+00 1169.00
IUUC-Gma-044252 Glycine max 35.77 3.00e-86 313.00
IUUC-Ggo-045430 Gorilla gorilla 97.12 0.00e+00 1778.00
IUUC-Hsa-046442 Homo sapiens 96.92 0.00e+00 1775.00
IUUC-Hvu-047587 Hordeum vulgare 36.98 1.00e-80 294.00
IUUC-Itr-048910 Ictidomys tridecemlineatus 99.67 1.00e-175 608.00
IUUC-Kpa-049145 Komagataella pastoris 31.36 1.00e-58 221.00
IUUC-Lch-050474 Latimeria chalumnae 75.65 0.00e+00 1389.00
IUUC-Lpe-051209 Leersia perrieri 36.15 4.00e-81 296.00
IUUC-Loc-052119 Lepisosteus oculatus 71.54 0.00e+00 1343.00
IUUC-Lma-053237 Leptosphaeria maculans 31.90 3.00e-64 240.00
IUUC-Laf-053718 Loxodonta africana 94.25 0.00e+00 1739.00
IUUC-Mcc-055621 Macaca mulatta 97.03 0.00e+00 1709.00
IUUC-Meu-055914 Macropus eugenii 79.96 0.00e+00 1438.00
IUUC-Mor-057090 Magnaporthe oryzae 34.09 7.00e-64 239.00
IUUC-Mpo-057364 Magnaporthe poae 32.25 2.00e-68 254.00
IUUC-Mtr-057744 Medicago truncatula 37.52 3.00e-87 317.00
IUUC-Mla-058914 Melampsora laricipopulina 36.78 8.00e-82 298.00
IUUC-Mga-060181 Meleagris gallopavo 83.27 0.00e+00 1635.00
IUUC-Mvi-060432 Microbotryum violaceum 38.50 1.00e-72 268.00
IUUC-Mmr-060871 Microcebus murinus 96.92 0.00e+00 1833.00
IUUC-Mdo-062301 Monodelphis domestica 86.08 0.00e+00 1586.00
IUUC-Mmu-063888 Mus musculus 94.84 0.00e+00 1738.00
IUUC-Mac-065137 Musa acuminata 38.13 6.00e-87 315.00
IUUC-Mpu-066732 Mustela putorius furo 94.98 0.00e+00 1789.00
IUUC-Mlu-067542 Myotis lucifugus 94.84 0.00e+00 1705.00
IUUC-Nfi-068396 Neosartorya fischeri 33.99 2.00e-58 220.00
IUUC-Ncr-068842 Neurospora crassa 32.25 2.00e-64 241.00
IUUC-Nle-070156 Nomascus leucogenys 96.83 0.00e+00 1786.00
IUUC-Opr-070808 Ochotona princeps 94.58 0.00e+00 1427.00
IUUC-Ont-072105 Oreochromis niloticus 67.28 0.00e+00 1304.00
IUUC-Ocu-074962 Oryctolagus cuniculus 95.64 0.00e+00 1779.00
IUUC-Oba-075178 Oryza barthii 35.66 3.00e-87 317.00
IUUC-Obr-076399 Oryza brachyantha 36.97 4.00e-89 323.00
IUUC-Ogu-078797 Oryza glumaepatula 35.66 3.00e-87 317.00
IUUC-Oin-080085 Oryza indica 34.45 2.00e-78 287.00
IUUC-Olo-081048 Oryza longistaminata 41.04 3.00e-66 247.00
IUUC-Ome-081324 Oryza meridionalis 36.21 2.00e-87 317.00
IUUC-Oni-082548 Oryza nivara 35.66 3.00e-87 317.00
IUUC-Opu-084008 Oryza punctata 41.93 4.00e-87 316.00
IUUC-Oru-084339 Oryza rufipogon 35.48 9.00e-87 315.00
IUUC-Osa-085782 Oryza sativa 35.48 9.00e-87 315.00
IUUC-Ola-087302 Oryzias latipes 67.87 0.00e+00 784.00
IUUC-Olu-087611 Ostreococcus lucimarinus 35.68 3.00e-86 313.00
IUUC-Oar-089229 Ovis aries 69.52 0.00e+00 1055.00
IUUC-Ptr-090715 Pan troglodytes 96.92 0.00e+00 1773.00
IUUC-Pan-092318 Papio anubis 97.03 0.00e+00 1786.00
IUUC-Psi-094053 Pelodiscus sinensis 83.94 0.00e+00 1616.00
IUUC-Pno-094985 Phaeosphaeria nodorum 33.51 1.00e-56 215.00
IUUC-Ppa-095819 Physcomitrella patens 39.49 1.00e-84 308.00
IUUC-Pfo-096857 Poecilia formosa 66.44 0.00e+00 1255.00
IUUC-Pab-098047 Pongo abelii 97.12 0.00e+00 1778.00
IUUC-Pop-099865 Populus trichocarpa 37.63 5.00e-86 312.00
IUUC-Pca-100558 Procavia capensis 93.44 0.00e+00 736.00
IUUC-Ppe-101261 Prunus persica 37.97 3.00e-88 319.00
IUUC-Pva-102683 Pteropus vampyrus 94.94 0.00e+00 1758.00
IUUC-Pgr-103660 Puccinia graminis 41.21 5.00e-74 272.00
IUUC-Ptt-103900 Puccinia triticina 41.91 1.00e-75 277.00
IUUC-Pte-104209 Pyrenophora teres 34.15 1.00e-61 231.00
IUUC-Pyt-104802 Pyrenophora triticirepentis 34.15 6.00e-61 229.00
IUUC-Rno-105137 Rattus norvegicus 94.19 0.00e+00 1768.00
IUUC-Sce-106291 Saccharomyces cerevisiae 32.90 1.00e-59 224.00
IUUC-Sha-107514 Sarcophilus harrisii 81.42 0.00e+00 1486.00
IUUC-Sja-107833 Schizosaccharomyces japonicus 34.11 3.00e-77 283.00
IUUC-Spo-108162 Schizosaccharomyces pombe 36.93 1.00e-76 281.00
IUUC-Smo-109186 Selaginella moellendorffii 40.83 5.00e-86 312.00
IUUC-Sit-110730 Setaria italica 37.45 1.00e-87 318.00
IUUC-Sly-111547 Solanum lycopersicum 38.19 1.00e-89 324.00
IUUC-Stu-112705 Solanum tuberosum 37.99 1.00e-89 325.00
IUUC-Sar-113222 Sorex araneus 89.47 0.00e+00 1537.00
IUUC-Sbi-114272 Sorghum bicolor 37.88 7.00e-89 322.00
IUUC-Sre-115061 Sporisorium reilianum 26.65 1.00e-88 321.00
IUUC-Ssc-116364 Sus scrofa 94.18 0.00e+00 1847.00
IUUC-Tgu-116645 Taeniopygia guttata 84.32 0.00e+00 1639.00
IUUC-Tru-117590 Takifugu rubripes 66.28 0.00e+00 1270.00
IUUC-Tsy-119212 Tarsius syrichta 91.36 0.00e+00 1002.00
IUUC-Tni-119915 Tetraodon nigroviridis 66.47 0.00e+00 1245.00
IUUC-Tca-121765 Theobroma cacao 37.17 2.00e-86 313.00
IUUC-Tre-121887 Trichoderma reesei 34.02 1.00e-56 214.00
IUUC-Tvi-122262 Trichoderma virens 34.02 2.00e-56 214.00
IUUC-Tae-124148 Triticum aestivum 44.57 8.00e-35 142.00
IUUC-Tur-126483 Triticum urartu 37.37 9.00e-90 325.00
IUUC-Tme-127202 Tuber melanosporum 31.11 8.00e-55 209.00
IUUC-Tbe-127350 Tupaia belangeri 83.90 0.00e+00 649.00
IUUC-Ttr-129077 Tursiops truncatus 89.97 0.00e+00 1763.00
IUUC-Uma-129465 Ustilago maydis 35.71 8.00e-77 281.00
IUUC-Vda-129844 Verticillium dahliae 34.70 5.00e-63 236.00
IUUC-Vvi-131397 Vitis vinifera 37.35 8.00e-88 318.00
IUUC-Xtr-132057 Xenopus tropicalis 75.57 0.00e+00 1401.00
IUUC-Xma-134139 Xiphophorus maculatus 68.06 0.00e+00 800.00
IUUC-Yli-134424 Yarrowia lipolytica 32.20 1.00e-63 238.00
IUUC-Zma-135839 Zea mays 36.84 2.00e-88 320.00
Created Date 25-Jun-2017

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