iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Xma-134297

Ensembl Protein ID

ENSXMAP00000007731.1

UniProt Accession

M3ZZT7; M3ZZT7_XIPMA

Genbank Protein ID

ENSXMAP00000007731

Protein Name

Inhibitor of growth protein

Genbank Nucleotide ID

AGAJ01023603

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSXMAG00000007709.1	ENSXMAT00000007739.1	ENSXMAP00000007731.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/RING/PHD	7.30e-09	35.7	222	268

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 activity/RING/PHD

   S: 2    kvClvCgeggedekslveCek..Cr.ewfHpaClklsveeelpnsekwiCpkCr 52
           ++C +C++ + +e  ++ C++  C+ ewfH+ C++l+    +p+ + w+CpkCr
   Q: 222  TYC-LCEQVSYGE--MIGCDNdqCHiEWFHFSCVGLT---YKPKGK-WYCPKCR 268
           69*.*******99..*****99***************...888886.******8 PP

Organism

Xiphophorus maculatus

Protein Sequence
(Fasta)

ALLCIAETML GHHYQNADKS QQLVNYVEDY LECVESLPLD IQRNVSLLRE IDAKYQEVLK 60
EVDEVFEKYK GEQDSAQRKR LQIQLQRALI LSQELGDEKI HVVTQMTELV ENRSRQMDSH 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GCGCTTCTAT GCATCGCAGA GACGATGTTA GGCCATCATT ATCAGAATGC GGACAAGTCG 60
CAGCAACTAG TCAACTATGT GGAGGATTAC CTGGAATGTG TGGAGTCCCT GCCTCTGGAC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0156--Chromatin regulator
KW-0181--Complete proteome
KW-0479--Metal-binding
KW-0539--Nucleus
KW-1185--Reference proteome
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR028639--ING2
IPR028651--ING_fam
IPR024610--ING_N_histone_binding
IPR019786--Zinc_finger_PHD-type_CS
IPR011011--Znf_FYVE_PHD
IPR001965--Znf_PHD
IPR019787--Znf_PHD-finger
IPR013083--Znf_RING/FYVE/PHD

PROSITE

PS01359--ZF_PHD_1
PS50016--ZF_PHD_2

Pfam

PF12998--ING

SMART

SM01408--ING
SM00249--PHD

Gene Ontology

GO:0005634--C:nucleus
GO:0003682--F:chromatin binding
GO:0008270--F:zinc ion binding
GO:0016569--P:covalent chromatin modification
GO:0008285--P:negative regulation of cell proliferation
GO:0042981--P:regulation of apoptotic process
GO:2000772--P:regulation of cellular senescence

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Apl-003910	Anas platyrhynchos	56.23	8.00e-74	270.00
IUUC-Aca-004990	Anolis carolinensis	66.67	2.00e-83	301.00
IUUC-Ame-011426	Astyanax mexicanus	68.55	2.00e-88	318.00
IUUC-Bta-013507	Bos taurus	53.48	4.00e-55	207.00
IUUC-Cja-018925	Callithrix jacchus	56.60	1.00e-74	273.00
IUUC-Csa-023304	Chlorocebus sabaeus	66.30	4.00e-70	257.00
IUUC-Dre-028562	Danio rerio	73.94	4.00e-98	350.00
IUUC-Dse-031323	Dothistroma septosporum	56.06	3.00e-18	87.00
IUUC-Ete-032709	Echinops telfairi	64.96	1.00e-84	305.00
IUUC-Eeu-035285	Erinaceus europaeus	66.05	3.00e-61	227.00
IUUC-Fal-036838	Ficedula albicollis	56.23	8.00e-74	270.00
IUUC-Gmo-038748	Gadus morhua	78.17	6.00e-113	400.00
IUUC-Gga-040619	Gallus gallus	56.98	2.00e-74	272.00
IUUC-Gac-041403	Gasterosteus aculeatus	88.61	3.00e-134	470.00
IUUC-Ggo-045481	Gorilla gorilla	52.16	4.00e-56	211.00
IUUC-Hsa-045837	Homo sapiens	66.30	4.00e-70	257.00
IUUC-Lch-049965	Latimeria chalumnae	65.11	2.00e-83	301.00
IUUC-Mcc-055031	Macaca mulatta	52.38	5.00e-56	211.00
IUUC-Meu-056470	Macropus eugenii	68.56	3.00e-84	304.00
IUUC-Mga-059570	Meleagris gallopavo	66.67	2.00e-68	251.00
IUUC-Mdo-062144	Monodelphis domestica	68.56	5.00e-84	304.00
IUUC-Mmu-063215	Mus musculus	65.57	9.00e-77	280.00
IUUC-Nle-069122	Nomascus leucogenys	56.98	6.00e-75	273.00
IUUC-Ont-071524	Oreochromis niloticus	94.08	3.00e-138	484.00
IUUC-Oan-073023	Ornithorhynchus anatinus	56.60	3.00e-73	268.00
IUUC-Ocu-073779	Oryctolagus cuniculus	53.81	4.00e-59	221.00
IUUC-Ola-087400	Oryzias latipes	89.27	7.00e-88	316.00
IUUC-Oar-090006	Ovis aries	56.98	6.00e-75	273.00
IUUC-Ptr-090589	Pan troglodytes	56.60	1.00e-74	272.00
IUUC-Pan-092819	Papio anubis	66.30	4.00e-70	257.00
IUUC-Psi-093266	Pelodiscus sinensis	57.36	3.00e-75	275.00
IUUC-Pfo-096633	Poecilia formosa	99.65	4.00e-138	483.00
IUUC-Pab-098346	Pongo abelii	66.30	8.00e-70	256.00
IUUC-Pca-100278	Procavia capensis	66.29	1.00e-81	295.00
IUUC-Pva-103190	Pteropus vampyrus	66.30	5.00e-77	280.00
IUUC-Rno-105964	Rattus norvegicus	53.48	9.00e-55	206.00
IUUC-Sha-107533	Sarcophilus harrisii	68.56	6.00e-84	303.00
IUUC-Sar-113630	Sorex araneus	66.51	7.00e-61	226.00
IUUC-Ssc-115734	Sus scrofa	65.20	6.00e-77	280.00
IUUC-Tgu-116822	Taeniopygia guttata	56.23	5.00e-74	270.00
IUUC-Tru-118168	Takifugu rubripes	84.34	4.00e-112	397.00
IUUC-Tsy-119494	Tarsius syrichta	65.50	2.00e-55	208.00
IUUC-Tni-119663	Tetraodon nigroviridis	83.63	4.00e-113	400.00
IUUC-Tvi-122341	Trichoderma virens	60.34	5.00e-16	77.00
IUUC-Ttr-128442	Tursiops truncatus	65.58	6.00e-61	226.00
IUUC-Vpa-130063	Vicugna pacos	66.06	2.00e-77	281.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence