iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Pyt-104696

Ensembl Protein ID

EDU44734

UniProt Accession

B2WNX4; B2WNX4_PYRTR

Genbank Protein ID

EDU44734.1

Protein Name

Ubiquitinyl hydrolase 1

Genbank Nucleotide ID

DS231632

Gene Name

PTRG_11684

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
PTRG_11684	EDU44734	EDU44734

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
DUB/USP	3.30e-50	170.5	302	800
UBD/Alpha-Helix/UBA	1.30e-19	69.0	600	639

Active Site

Position(s)	Description	Evidence
311	Nucleophile	{ECO:0000256\|PIRSR:PIRSR016308-1}
755	Proton acceptor	{ECO:0000256\|PIRSR:PIRSR016308-1}

Domain Profile

DUB/USP

   S: 1    tGlkNlgNtCYmNSvLQcLsnipelrelllekkkeklneenpkepkgellkslqklfeelwkskkk...................avsprellkalkkeae 82
           tGlkNlgN+CY+NS+LQ+L+++pe+++ +     +  ++     p ++l ++l+k+   + +++ +                     +p +l++ +++ ++
   Q: 302  TGLKNLGNSCYLNSTLQALFSMPEFKQRYYL-PDQGPPDA--VLPAEDLETQLRKIADGIISGRYSkpdtdvitneyspeiphqrGLAPAMLKHLIGRGHP 399
           7**************************9999.33333332..45777777788887777752222222344555555555666669*************** PP
   S: 83   efsgyeqqDaqEflaflldqleeelkkeknkpkeeeeeedkselsdeaeekkkkknkslisdlFqgqlksqikclecdnvssreepfldlslpvpgkeetk 183
           efs+++qqDa E+l ++l+ ++++                            +   ++  ++ F + ++++++c  c++v  r+++   +s+pvp ++  k
   Q: 400  EFSTMRQQDAFELLLHVLKLISRSQ---------------------------HVAPHKDPVEAFCFAMEQRLQCVGCKRVRYRTDEQENISIPVPIRRIPK 473
           *********************9988...........................34455556678********************************999887 PP
   S: 184  ke....................slqdcLesftkeeelegenkyycekckkkqeaekklklkklPevLilhLkRfsfseeqksrekinkkvefple.Ldlsp 263
           ++                    sl++cL+ ft+ee +e    + c+ c +k   +k+ ++k++P vL ++  Rf  +  +++++k +  v + +e ++ + 
   Q: 474  ESqmdvtdgngkkeekeefepvSLKECLDIFTAEELVE----LTCSACGSKDGFTKRSMFKTFPSVLAINARRF--ELVNWVPTKQDVPVIVDDEpFSFDA 568
           7799999****************************999....9*******************************..6688********************* PP
   S: 264  fcts................................................................................................. 267
           + ++                                                                                                 
   Q: 569  YKSKglsegeellpdemdtgavggssnkwtpneaalsmleamgfprvrcekalhatgnedaeaasmwlfshmedadidepvdfnassgsataatsvidpek 669
           ***98888888888888888888888888888888887777777777777777777777666666666666666666666666666666666666665555 PP
   S: 268  ...........peekqke....................................................kkkYeLiavvvHsG.slssGHYvayvkn... 301
                      p     +                                                    + k++L ++v+H+G s++ GHYva+v++   
   Q: 670  idnlgamgfnaP-----QarqalketggdmeravdwlfshpdapgdfdeggdaeaateqtekvlagsdqlPAKFQLQSIVCHKGsSIHAGHYVAFVRKqlp 765
           555555555550.....05555555555666666666666666666666666666777777788899999****************************776 PP
   S: 302  ..ekgk..WllfdDskVtevkeeevleetgstaYvlfYkr 337
             +  +  W+lf+D+kV +   ++v+e++ + aYv+f++r
   Q: 766  deT--GasWVLFNDEKVAKA--ADVEEMK-KFAYVYFFRR 800
           533..246*********999..5555543.79******97 PP

UBD/Alpha-Helix/UBA

   S: 3    dedkleqlveMGFdreealqaLraa.nnnleaAveyLldg 41
           +e +l  l++MGF+r ++ +aL a+ n ++eaA+++L+++
   Q: 600  NEAALSMLEAMGFPRVRCEKALHATgNEDAEAASMWLFSH 639
           5678889999****************************97 PP

Organism

Pyrenophora triticirepentis

Protein Sequence
(Fasta)

MACTHVNAPE LHPPGPTQSV YREDCTQCFD SIDDPTGLDV CLYCFNGGCT SDRGHALLHV 60
SSTNHPLVLN IKRTRKRVKR DEPPQKMTKL AVAAETESDR YDTTTQVKCY ECNVDDVDKS 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGGCTTGTA CGCATGTCAA CGCGCCAGGT ATGTGTGTAT CTCCGTATCT GCCGCAAAAC 60
GGGACATGGA ACATGGGACA TGCGGGCAAG GCCGCCTGCT TGGAACCTGG CCTGGAGCTA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0378--Hydrolase
KW-0479--Metal-binding
KW-0645--Protease
KW-1185--Reference proteome
KW-0788--Thiol protease
KW-0833--Ubl conjugation pathway
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR001394--Peptidase_C19_UCH
IPR015940--UBA
IPR009060--UBA-like
IPR016652--Ubiquitinyl_hydrolase
IPR018200--USP_CS
IPR028889--USP_dom
IPR013083--Znf_RING/FYVE/PHD
IPR001607--Znf_UBP

PROSITE

PS50030--UBA
PS00972--USP_1
PS00973--USP_2
PS50235--USP_3
PS50271--ZF_UBP

Pfam

PF00627--UBA
PF00443--UCH
PF02148--zf-UBP

SMART

SM00165--UBA
SM00290--ZnF_UBP

Gene Ontology

GO:0004843--F:thiol-dependent ubiquitin-specific protease activity
GO:0008270--F:zinc ion binding
GO:0016579--P:protein deubiquitination
GO:0006511--P:ubiquitin-dependent protein catabolic process

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000394	Aegilops tauschii	31.82	1.00e-99	355.00
IUUC-Aml-002104	Ailuropoda melanoleuca	33.37	1.00e-125	442.00
IUUC-Atr-002580	Amborella trichopoda	33.18	3.00e-115	407.00
IUUC-Apl-003774	Anas platyrhynchos	34.49	5.00e-126	443.00
IUUC-Aca-005368	Anolis carolinensis	34.49	1.00e-132	465.00
IUUC-Aly-005727	Arabidopsis lyrata	34.41	3.00e-121	427.00
IUUC-Ath-006974	Arabidopsis thaliana	34.89	6.00e-123	433.00
IUUC-Ago-007890	Ashbya gossypii	31.43	9.00e-107	379.00
IUUC-Acl-008057	Aspergillus clavatus	57.77	0.00e+00	947.00
IUUC-Afl-008547	Aspergillus flavus	58.46	0.00e+00	821.00
IUUC-Afu-008805	Aspergillus fumigatus	55.44	0.00e+00	852.00
IUUC-Ani-009441	Aspergillus nidulans	54.63	0.00e+00	765.00
IUUC-Ang-009720	Aspergillus niger	58.70	0.00e+00	958.00
IUUC-Aor-010111	Aspergillus oryzae	59.25	0.00e+00	996.00
IUUC-Ate-010531	Aspergillus terreus	53.93	0.00e+00	854.00
IUUC-Ame-011893	Astyanax mexicanus	33.55	2.00e-105	374.00
IUUC-Bgr-012183	Blumeria graminis	58.88	0.00e+00	969.00
IUUC-Bta-013179	Bos taurus	33.10	3.00e-123	434.00
IUUC-Bci-013858	Botrytis cinerea	65.79	0.00e+00	1103.00
IUUC-Bdi-014904	Brachypodium distachyon	33.74	4.00e-107	380.00
IUUC-Bol-015296	Brassica oleracea	33.77	4.00e-122	430.00
IUUC-Bra-017939	Brassica rapa	34.49	1.00e-124	439.00
IUUC-Cel-018625	Caenorhabditis elegans	30.33	5.00e-86	310.00
IUUC-Cja-019063	Callithrix jacchus	33.45	1.00e-123	435.00
IUUC-Cfa-020976	Canis familiaris	33.77	1.00e-127	449.00
IUUC-Cpo-022265	Cavia porcellus	33.85	4.00e-128	450.00
IUUC-Cre-022640	Chlamydomonas reinhardtii	33.33	2.00e-69	255.00
IUUC-Csa-024078	Chlorocebus sabaeus	31.48	9.00e-109	386.00
IUUC-Cho-024702	Choloepus hoffmanni	31.36	4.00e-75	274.00
IUUC-Cin-025411	Ciona intestinalis	33.09	1.00e-106	379.00
IUUC-Csv-026347	Ciona savignyi	31.80	7.00e-108	383.00
IUUC-Cgl-026667	Colletotrichum gloeosporioides	62.94	0.00e+00	963.00
IUUC-Cne-026831	Cryptococcus neoformans	45.31	0.00e+00	632.00
IUUC-Cme-027335	Cyanidioschyzon merolae	31.97	7.00e-61	227.00
IUUC-Dre-027982	Danio rerio	32.21	3.00e-109	387.00
IUUC-Dno-029034	Dasypus novemcinctus	33.33	1.00e-126	445.00
IUUC-Dor-030479	Dipodomys ordii	35.07	2.00e-57	215.00
IUUC-Dse-031467	Dothistroma septosporum	62.93	0.00e+00	1003.00
IUUC-Dme-032075	Drosophila melanogaster	34.68	1.00e-117	415.00
IUUC-Ete-032865	Echinops telfairi	29.75	2.00e-101	362.00
IUUC-Eca-034059	Equus caballus	33.22	3.00e-124	437.00
IUUC-Eeu-035304	Erinaceus europaeus	34.40	1.00e-116	412.00
IUUC-Fca-035515	Felis catus	33.22	5.00e-125	440.00
IUUC-Fal-037271	Ficedula albicollis	35.19	2.00e-122	431.00
IUUC-Fox-037745	Fusarium oxysporum	63.42	0.00e+00	1020.00
IUUC-Fso-038158	Fusarium solani	64.79	0.00e+00	1033.00
IUUC-Gmo-039071	Gadus morhua	32.81	1.00e-108	385.00
IUUC-Ggr-040098	Gaeumannomyces graminis	62.09	0.00e+00	956.00
IUUC-Gga-040635	Gallus gallus	33.95	1.00e-129	455.00
IUUC-Gac-042528	Gasterosteus aculeatus	33.05	1.00e-113	402.00
IUUC-Gma-043614	Glycine max	34.45	3.00e-116	411.00
IUUC-Ggo-044602	Gorilla gorilla	33.33	1.00e-125	442.00
IUUC-Hsa-045959	Homo sapiens	33.33	1.00e-125	442.00
IUUC-Hvu-047563	Hordeum vulgare	36.24	4.00e-104	370.00
IUUC-Itr-048712	Ictidomys tridecemlineatus	33.76	2.00e-127	448.00
IUUC-Kpa-049156	Komagataella pastoris	41.02	3.00e-174	603.00
IUUC-Lch-049648	Latimeria chalumnae	33.81	2.00e-122	431.00
IUUC-Lpe-051523	Leersia perrieri	32.93	2.00e-108	384.00
IUUC-Loc-052072	Lepisosteus oculatus	30.91	6.00e-111	393.00
IUUC-Lma-053216	Leptosphaeria maculans	83.11	0.00e+00	1364.00
IUUC-Laf-054327	Loxodonta africana	33.22	2.00e-124	438.00
IUUC-Mcc-055443	Macaca mulatta	33.33	2.00e-125	441.00
IUUC-Meu-056298	Macropus eugenii	33.51	2.00e-86	312.00
IUUC-Mor-057106	Magnaporthe oryzae	61.55	0.00e+00	997.00
IUUC-Mpo-057589	Magnaporthe poae	63.14	0.00e+00	971.00
IUUC-Mtr-058680	Medicago truncatula	34.13	2.00e-121	428.00
IUUC-Mla-058903	Melampsora laricipopulina	43.35	2.00e-179	621.00
IUUC-Mga-059669	Meleagris gallopavo	34.09	1.00e-122	432.00
IUUC-Mvi-060476	Microbotryum violaceum	45.11	3.00e-180	623.00
IUUC-Mmr-060575	Microcebus murinus	33.22	4.00e-125	440.00
IUUC-Mdo-062183	Monodelphis domestica	34.00	2.00e-126	444.00
IUUC-Mmu-063592	Mus musculus	33.33	5.00e-126	443.00
IUUC-Mac-065446	Musa acuminata	32.27	3.00e-108	384.00
IUUC-Mpu-066082	Mustela putorius furo	33.77	4.00e-127	447.00
IUUC-Mlu-067345	Myotis lucifugus	33.45	5.00e-125	440.00
IUUC-Nfi-068558	Neosartorya fischeri	57.99	0.00e+00	917.00
IUUC-Ncr-068960	Neurospora crassa	62.06	0.00e+00	969.00
IUUC-Nle-070173	Nomascus leucogenys	33.77	2.00e-127	447.00
IUUC-Opr-070556	Ochotona princeps	34.26	3.00e-129	454.00
IUUC-Ont-071502	Oreochromis niloticus	33.69	2.00e-113	402.00
IUUC-Oan-072959	Ornithorhynchus anatinus	42.29	4.00e-48	182.00
IUUC-Ocu-074861	Oryctolagus cuniculus	34.37	5.00e-129	453.00
IUUC-Oba-075109	Oryza barthii	32.85	6.00e-111	393.00
IUUC-Obr-076292	Oryza brachyantha	33.13	1.00e-103	369.00
IUUC-Ogl-077065	Oryza glaberrima	33.41	6.00e-115	406.00
IUUC-Ogu-078776	Oryza glumaepatula	33.33	9.00e-116	409.00
IUUC-Oin-080048	Oryza indica	33.78	3.00e-115	407.00
IUUC-Olo-080711	Oryza longistaminata	32.75	3.00e-104	371.00
IUUC-Ome-081506	Oryza meridionalis	33.59	6.00e-107	380.00
IUUC-Oni-082320	Oryza nivara	32.54	3.00e-110	390.00
IUUC-Opu-083801	Oryza punctata	33.41	9.00e-106	376.00
IUUC-Oru-085139	Oryza rufipogon	32.42	2.00e-110	391.00
IUUC-Osa-085713	Oryza sativa	33.90	3.00e-116	410.00
IUUC-Ola-086951	Oryzias latipes	31.57	1.00e-107	382.00
IUUC-Olu-087822	Ostreococcus lucimarinus	32.50	1.00e-102	365.00
IUUC-Oga-088625	Otolemur garnettii	33.76	3.00e-126	444.00
IUUC-Oar-089995	Ovis aries	33.60	7.00e-126	443.00
IUUC-Ptr-090640	Pan troglodytes	33.68	4.00e-127	447.00
IUUC-Pan-091974	Papio anubis	33.80	4.00e-127	447.00
IUUC-Psi-093957	Pelodiscus sinensis	33.91	4.00e-130	457.00
IUUC-Pma-094242	Petromyzon marinus	39.64	7.00e-75	272.00
IUUC-Pno-094835	Phaeosphaeria nodorum	80.97	0.00e+00	1248.00
IUUC-Ppa-095901	Physcomitrella patens	35.27	1.00e-126	445.00
IUUC-Pfo-097148	Poecilia formosa	34.25	2.00e-114	405.00
IUUC-Pab-098068	Pongo abelii	31.16	2.00e-105	374.00
IUUC-Pop-098943	Populus trichocarpa	34.01	1.00e-115	408.00
IUUC-Pca-100738	Procavia capensis	34.26	6.00e-91	327.00
IUUC-Ppe-101315	Prunus persica	33.29	5.00e-114	403.00
IUUC-Pva-102154	Pteropus vampyrus	32.87	3.00e-122	431.00
IUUC-Pgr-103343	Puccinia graminis	42.75	2.00e-145	507.00
IUUC-Ptt-103928	Puccinia triticina	36.63	4.00e-138	483.00
IUUC-Pte-104306	Pyrenophora teres	97.22	0.00e+00	1467.00
IUUC-Rno-105801	Rattus norvegicus	33.45	2.00e-126	444.00
IUUC-Sce-106304	Saccharomyces cerevisiae	32.97	6.00e-113	400.00
IUUC-Sha-107635	Sarcophilus harrisii	34.21	9.00e-127	446.00
IUUC-Sja-107678	Schizosaccharomyces japonicus	43.11	4.00e-179	619.00
IUUC-Spo-108144	Schizosaccharomyces pombe	42.27	2.00e-179	620.00
IUUC-Smo-108703	Selaginella moellendorffii	35.42	4.00e-120	424.00
IUUC-Sit-110728	Setaria italica	33.17	6.00e-114	403.00
IUUC-Sly-111523	Solanum lycopersicum	35.34	1.00e-128	452.00
IUUC-Sar-113733	Sorex araneus	34.63	1.00e-61	229.00
IUUC-Sbi-114419	Sorghum bicolor	32.52	3.00e-110	391.00
IUUC-Sre-115225	Sporisorium reilianum	43.23	0.00e+00	636.00
IUUC-Ssc-115686	Sus scrofa	33.76	2.00e-126	444.00
IUUC-Tgu-117346	Taeniopygia guttata	33.84	5.00e-124	436.00
IUUC-Tru-118350	Takifugu rubripes	32.79	1.00e-115	408.00
IUUC-Tsy-119278	Tarsius syrichta	31.23	2.00e-91	328.00
IUUC-Tni-120658	Tetraodon nigroviridis	32.28	3.00e-109	387.00
IUUC-Tca-121585	Theobroma cacao	34.17	2.00e-119	421.00
IUUC-Tre-122043	Trichoderma reesei	62.64	0.00e+00	969.00
IUUC-Tvi-122303	Trichoderma virens	63.05	0.00e+00	994.00
IUUC-Tae-123798	Triticum aestivum	33.25	5.00e-114	403.00
IUUC-Tur-126732	Triticum urartu	31.39	9.00e-103	365.00
IUUC-Tme-126909	Tuber melanosporum	61.94	0.00e+00	970.00
IUUC-Tbe-127261	Tupaia belangeri	29.58	3.00e-70	258.00
IUUC-Ttr-128295	Tursiops truncatus	28.74	4.00e-88	317.00
IUUC-Uma-129599	Ustilago maydis	44.89	0.00e+00	668.00
IUUC-Vda-129688	Verticillium dahliae	61.80	0.00e+00	962.00
IUUC-Vpa-130170	Vicugna pacos	34.00	2.00e-50	192.00
IUUC-Vvi-131116	Vitis vinifera	34.77	3.00e-119	421.00
IUUC-Xtr-131953	Xenopus tropicalis	32.95	6.00e-114	403.00
IUUC-Xma-133837	Xiphophorus maculatus	33.78	1.00e-114	405.00
IUUC-Yli-134510	Yarrowia lipolytica	44.54	1.00e-179	621.00
IUUC-Zma-135786	Zea mays	32.97	1.00e-104	372.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence