iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Aca-004380

Ensembl Protein ID

ENSACAP00000001053.2

UniProt Accession

H9G4Q3; H9G4Q3_ANOCA

Protein Name

Coronin

Gene Name

CORO1C

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSACAG00000000937.2	ENSACAT00000001082.2	ENSACAP00000001053.2

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	6.30e-18	64.1	81	112

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 1    gHtdsvtclaf...sdtllvsGsdDgtikvWD 29
           gHt++v ++++   +d+ ++sGs D+t++vW 
   Q: 81   GHTGPVLDIDWcphNDHVIASGSEDCTVMVWQ 112
           8***********977799*************7 PP

Organism

Anolis carolinensis

Protein Sequence
(Fasta)

AETMRRVVRQ SKFRHVFGQA VKNDQCYDDI RVSRVTWDSA FCAVNPKFVA IIVEASGGGA 60
FLVLPLHKTG RIDKAYPTVC GHTGPVLDID WCPHNDHVIA SGSEDCTVMV WQIPENGLAL 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GCAGAAACCA TGCGGCGGGT GGTGCGGCAG AGCAAATTCC GGCACGTCTT TGGCCAGGCG 60
GTGAAGAATG ACCAGTGCTA CGACGACATC CGTGTCTCCC GTGTCACATG GGACAGCGCC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0677--Repeat
KW-0853--WD repeat

Interpro

IPR027333--CORO1C
IPR015505--Coronin
IPR015048--DUF1899
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF08953--DUF1899
PF00400--WD40

SMART

SM01166--DUF1899
SM00320--WD40

Gene Ontology

GO:0015629--C:actin cytoskeleton
GO:0016600--C:flotillin complex
GO:0005925--C:focal adhesion
GO:0030027--C:lamellipodium
GO:0016328--C:lateral plasma membrane
GO:0031982--C:vesicle
GO:0051015--F:actin filament binding
GO:0030036--P:actin cytoskeleton organization
GO:0090630--P:activation of GTPase activity
GO:0045184--P:establishment of protein localization
GO:0010633--P:negative regulation of epithelial cell migration
GO:0051895--P:negative regulation of focal adhesion assembly
GO:0044387--P:negative regulation of protein kinase activity by regulation of protein phosphorylation
GO:1900025--P:negative regulation of substrate adhesion-dependent cell spreading
GO:0001755--P:neural crest cell migration
GO:2000394--P:positive regulation of lamellipodium morphogenesis
GO:0010762--P:regulation of fibroblast migration
GO:1900027--P:regulation of ruffle assembly

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence