iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Oan-072965

Ensembl Protein ID

ENSOANP00000024243.3

UniProt Accession

F6UET8; F6UET8_ORNAN

Protein Name

Uncharacterized protein

Gene Name

OPTN

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSOANG00000015410.3	ENSOANT00000024247.3	ENSOANP00000024243.3

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
UBD/Alpha-Helix/UBAN	4.60e-23	81.2	447	506

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

UBD/Alpha-Helix/UBAN

   S: 1    keelletvevLkqQveiYkeDFqaERadRErlneekeeLqeqveklqkqvsklndslkas 60
           +ee+l+t+ vL++Q+e+Y++DF+aERa+RE+++eeke+L+ q+  l+k+  +++d++++s
   Q: 447  QEEDLDTMAVLRAQMEVYCSDFHAERAAREKIHEEKEQLALQLTYLLKDSHAFEDGGRQS 506
           79*******************************************************998 PP

Organism

Ornithorhynchus anatinus

Protein Sequence
(Fasta)

MSSQPLSHPA GNGECPKPIT GNGPHNLVHP NLETFTPEEM LQQMKELLIE NHQLKEAMKL 60
NNQAMKGRFE ELSAWREKQK EERQFFESKF KEAKERLLAL SNEKEKLKQE LDDVKGEKKR 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

NNNNNNNNNN NNNNNNNNNN NNNNNNNNNN NNNNNNNNNN NNNNNNACCC CCGCCATGGA 60
GGGATCGCGG TGACCGGCCG CCTCCCCTGG TGAGCGGGGC CCCGGCGGGG AGGGACGGAG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR032419--CC2-LZ_dom
IPR021063--NEMO_N
IPR032939--Optineurin
IPR034735--ZF_CCHC_NOA

PROSITE

PS51801--ZF_CCHC_NOA

Pfam

PF16516--CC2-LZ
PF11577--NEMO

Gene Ontology

GO:0031410--C:cytoplasmic vesicle
GO:0005829--C:cytosol
GO:0005794--C:Golgi apparatus
GO:0005634--C:nucleus
GO:0048471--C:perinuclear region of cytoplasm
GO:0005802--C:trans-Golgi network
GO:0070530--F:K63-linked polyubiquitin binding
GO:0050829--P:defense response to Gram-negative bacterium
GO:0090161--P:Golgi ribbon formation
GO:0043001--P:Golgi to plasma membrane protein transport
GO:0016236--P:macroautophagy
GO:0043124--P:negative regulation of I-kappaB kinase/NF-kappaB signaling
GO:0001920--P:negative regulation of receptor recycling
GO:0061734--P:parkin-mediated stimulation of mitophagy in response to mitochondrial depolarization
GO:1904417--P:positive regulation of xenophagy
GO:0000042--P:protein targeting to Golgi
GO:0043122--P:regulation of I-kappaB kinase/NF-kappaB signaling

KEGG

oaa:100085347

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002037	Ailuropoda melanoleuca	68.74	0.00e+00	674.00
IUUC-Apl-003812	Anas platyrhynchos	57.12	5.00e-158	550.00
IUUC-Aca-004625	Anolis carolinensis	54.92	2.00e-149	521.00
IUUC-Aly-005781	Arabidopsis lyrata	45.00	5.10e-02	31.60
IUUC-Ame-011116	Astyanax mexicanus	45.42	6.00e-54	204.00
IUUC-Bta-013240	Bos taurus	71.92	0.00e+00	774.00
IUUC-Cja-019911	Callithrix jacchus	71.99	0.00e+00	737.00
IUUC-Cfa-020330	Canis familiaris	71.58	0.00e+00	726.00
IUUC-Cpo-021753	Cavia porcellus	70.17	0.00e+00	714.00
IUUC-Csa-023662	Chlorocebus sabaeus	72.85	0.00e+00	739.00
IUUC-Cho-024574	Choloepus hoffmanni	57.68	2.00e-101	362.00
IUUC-Cme-027299	Cyanidioschyzon merolae	35.62	3.90e-02	32.30
IUUC-Dre-027720	Danio rerio	41.02	2.00e-94	338.00
IUUC-Dno-029079	Dasypus novemcinctus	69.84	0.00e+00	646.00
IUUC-Dor-030890	Dipodomys ordii	69.88	0.00e+00	739.00
IUUC-Dme-032072	Drosophila melanogaster	27.01	4.00e-05	42.00
IUUC-Ete-032568	Echinops telfairi	70.97	0.00e+00	660.00
IUUC-Eca-033528	Equus caballus	69.56	0.00e+00	713.00
IUUC-Eeu-035219	Erinaceus europaeus	65.63	0.00e+00	686.00
IUUC-Fca-035852	Felis catus	72.16	0.00e+00	717.00
IUUC-Fal-036862	Ficedula albicollis	56.94	4.00e-149	520.00
IUUC-Gmo-038735	Gadus morhua	37.87	3.00e-73	268.00
IUUC-Gga-040939	Gallus gallus	56.33	4.00e-155	540.00
IUUC-Gac-041580	Gasterosteus aculeatus	41.92	2.00e-96	345.00
IUUC-Ggo-045034	Gorilla gorilla	65.62	0.00e+00	668.00
IUUC-Hsa-046624	Homo sapiens	72.60	0.00e+00	750.00
IUUC-Itr-048288	Ictidomys tridecemlineatus	66.15	0.00e+00	689.00
IUUC-Lch-049720	Latimeria chalumnae	48.46	4.00e-84	304.00
IUUC-Loc-052185	Lepisosteus oculatus	45.45	9.00e-107	380.00
IUUC-Laf-054079	Loxodonta africana	69.37	0.00e+00	694.00
IUUC-Mcc-055674	Macaca mulatta	73.44	0.00e+00	738.00
IUUC-Meu-056769	Macropus eugenii	84.52	9.00e-81	293.00
IUUC-Mga-060203	Meleagris gallopavo	56.21	4.00e-146	510.00
IUUC-Mmr-061492	Microcebus murinus	72.79	0.00e+00	721.00
IUUC-Mdo-063051	Monodelphis domestica	75.90	0.00e+00	802.00
IUUC-Mmu-063409	Mus musculus	68.43	0.00e+00	753.00
IUUC-Mpu-065907	Mustela putorius furo	66.33	0.00e+00	701.00
IUUC-Mlu-066957	Myotis lucifugus	70.36	0.00e+00	669.00
IUUC-Nle-069973	Nomascus leucogenys	72.85	0.00e+00	746.00
IUUC-Opr-071049	Ochotona princeps	66.67	0.00e+00	644.00
IUUC-Ont-071915	Oreochromis niloticus	42.54	6.00e-94	337.00
IUUC-Ocu-074029	Oryctolagus cuniculus	66.48	6.00e-171	592.00
IUUC-Ola-087019	Oryzias latipes	41.80	9.00e-92	330.00
IUUC-Oga-088613	Otolemur garnettii	71.06	0.00e+00	719.00
IUUC-Oar-090386	Ovis aries	71.58	0.00e+00	768.00
IUUC-Ptr-091619	Pan troglodytes	72.26	0.00e+00	744.00
IUUC-Pan-092178	Papio anubis	72.31	0.00e+00	731.00
IUUC-Psi-093214	Pelodiscus sinensis	61.47	8.00e-170	589.00
IUUC-Pfo-096901	Poecilia formosa	40.07	6.00e-89	320.00
IUUC-Pab-097560	Pongo abelii	67.53	0.00e+00	645.00
IUUC-Pca-100853	Procavia capensis	60.84	3.00e-94	338.00
IUUC-Pva-102255	Pteropus vampyrus	70.42	0.00e+00	673.00
IUUC-Rno-105812	Rattus norvegicus	70.29	0.00e+00	755.00
IUUC-Sha-107225	Sarcophilus harrisii	78.65	1.00e-155	541.00
IUUC-Sar-113736	Sorex araneus	67.78	3.00e-119	421.00
IUUC-Ssc-115422	Sus scrofa	72.62	0.00e+00	756.00
IUUC-Tgu-116924	Taeniopygia guttata	58.11	2.00e-147	514.00
IUUC-Tru-117695	Takifugu rubripes	39.47	1.00e-86	313.00
IUUC-Tsy-119090	Tarsius syrichta	70.03	2.00e-123	435.00
IUUC-Tni-120645	Tetraodon nigroviridis	40.55	4.00e-88	318.00
IUUC-Tbe-127970	Tupaia belangeri	78.82	2.00e-114	405.00
IUUC-Ttr-129244	Tursiops truncatus	69.72	0.00e+00	694.00
IUUC-Vpa-130313	Vicugna pacos	69.55	0.00e+00	681.00
IUUC-Xtr-132115	Xenopus tropicalis	44.53	2.00e-101	362.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence