iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Pab-098003

UUCD1 version

Ensembl Protein ID

UniProt Accession

Genbank Protein ID

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

ABGA01134245

Gene Name

USP34

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSPPYG00000012384.2	ENSPPYT00000014371.2	ENSPPYP00000013811.2

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
DUB/USP	1.30e-69	235.0	1725	2070

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

DUB/USP

   S: 1    tGlkNlgNtCYmNSvLQcLsnipelrellle.kkkeklneenpkepkgellkslqklfeelwkskkkavsprellkalkkeaeefsg 86
           +Gl+Nlg+tCY+ S++Q+L++ipe r+++++ k++e++       ++++ l +lqk+f+ l++s+ ka++pr + k+  + ++ +++
   Q: 1725 VGLTNLGATCYLASTIQQLYMIPEARQAVFTaKYSEDM-------KHKTTLLELQKMFTYLMESECKAYNPRPFCKTYTMDKQPLNT 1804
           6******************************3444444.......4568899*********************************** PP
   S: 87   yeqqDaqEflaflldqleeelkkeknkpkeeeeeedkselsdeaeekkkkknkslisdlFqgqlksqikclecdnvssreepfldls 173
            eq+D  Ef++ l+ ++ee                               + k++++ lF+g ++++++ l+c++vs++ e+f+++ 
   Q: 1805 GEQKDMTEFFTDLITKIEEMS----------------------------PELKNTVKSLFGGVITNNVVSLDCEHVSQTAEEFYTVR 1863
           *****************9977............................567899******************************** PP
   S: 174  lpvpgkeetkkeslqdcLesftkeeelegenkyycekckkkqeaekklklkklPevLilhLkRfsfseeqksrekinkkvefpleLd 260
           ++v + +     ++ ++L++ t +++leg+n+y c++c kk++aek+  +kklP++L+++ +R++f+  ++++ek+n++++fpl+Ld
   Q: 1864 CQVADMK-----NIYESLDEVTIKDTLEGDNMYTCSHCGKKVRAEKRACFKKLPRILSFNTMRYTFNMVTMMKEKVNTHFSFPLRLD 1945
           *******.....9************************************************************************** PP
   S: 261  lspfcts................peekqkekkkYeLiavvvHsGslssGHYvayvkn.......ekgkWllfdDskVtevkeeevle 324
           ++p++++                + +k++e+++Y+Li+v vH+G++++GHY++++++       +++kW+lf+D +V++ + ++  +
   Q: 1946 MTPYTEDflmgkserkegfkevsDHSKDSESYEYDLIGVTVHTGTADGGHYYSFIRDivnphayKNNKWYLFNDAEVKPFDSAQLAS 2032
           *******99999999999999986666667***************************99999988999******************9 PP
   S: 325  etg........................staYvlfYkrr 338
           e+                         ++aY+lfYkr+
   Q: 2033 ECFggemttktydsvtdkfmdfsfektHSAYMLFYKRM 2070
           7779********************************96 PP

Organism

Pongo abelii

Protein Sequence
(Fasta)

MRRKNSCYVW QIFQIQFPLY TAYKHNTHPT IEDVEVPLHL LRYVCLFCGK NGLSLMKDCF 60
EYGTPETLPF LIAHAFITVV SNIRIWLHIP AVMQHIIPFR TYVIRYLCKL SDQELRQSAA 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGAGAAGGA AAAACTCTTG CTATGTGTGG CAAAAATTTT TCAAATTCAG TTTCCCTTAT 60
ATACTGCTTA CAAGCATAAT ACTCACCCTA CTATTGAGGT ATGTAAAAAT AGGTGGTGTG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR011989--ARM-like
IPR016024--ARM-type_fold
IPR001394--Peptidase_C19_UCH
IPR018200--USP_CS
IPR028889--USP_dom

PROSITE

PS00972--USP_1
PS00973--USP_2
PS50235--USP_3

Pfam

PF00443--UCH

Gene Ontology

GO:0004197--F:cysteine-type endopeptidase activity
GO:0004843--F:thiol-dependent ubiquitin-specific protease activity
GO:0090263--P:positive regulation of canonical Wnt signaling pathway
GO:0071108--P:protein K48-linked deubiquitination
GO:0006511--P:ubiquitin-dependent protein catabolic process

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002257	Ailuropoda melanoleuca	97.84	0.00e+00	6500.00
IUUC-Apl-003284	Anas platyrhynchos	94.15	0.00e+00	6263.00
IUUC-Aca-004415	Anolis carolinensis	92.74	0.00e+00	6160.00
IUUC-Acl-008140	Aspergillus clavatus	32.39	4.00e-63	238.00
IUUC-Afl-008381	Aspergillus flavus	28.64	9.00e-63	236.00
IUUC-Afu-008857	Aspergillus fumigatus	27.05	2.00e-62	235.00
IUUC-Ani-009257	Aspergillus nidulans	28.49	6.00e-55	210.00
IUUC-Ang-009759	Aspergillus niger	27.41	1.00e-62	236.00
IUUC-Aor-009931	Aspergillus oryzae	28.64	1.00e-62	236.00
IUUC-Ate-010246	Aspergillus terreus	29.24	7.00e-53	204.00
IUUC-Ame-011219	Astyanax mexicanus	64.44	0.00e+00	2464.00
IUUC-Bgr-012195	Blumeria graminis	26.62	3.00e-63	238.00
IUUC-Bta-012989	Bos taurus	97.41	0.00e+00	6442.00
IUUC-Bci-013798	Botrytis cinerea	32.44	5.00e-58	221.00
IUUC-Cja-018974	Callithrix jacchus	97.17	0.00e+00	826.00
IUUC-Cfa-021214	Canis familiaris	98.02	0.00e+00	6516.00
IUUC-Cpo-021912	Cavia porcellus	97.51	0.00e+00	4423.00
IUUC-Csa-023658	Chlorocebus sabaeus	98.82	0.00e+00	6531.00
IUUC-Cho-024971	Choloepus hoffmanni	83.39	0.00e+00	3190.00
IUUC-Cgl-026466	Colletotrichum gloeosporioides	27.37	8.00e-63	237.00
IUUC-Dre-027428	Danio rerio	84.53	0.00e+00	4611.00
IUUC-Dno-029690	Dasypus novemcinctus	96.94	0.00e+00	6381.00
IUUC-Dor-030817	Dipodomys ordii	88.52	0.00e+00	2150.00
IUUC-Dse-031423	Dothistroma septosporum	25.23	1.00e-35	146.00
IUUC-Dme-032102	Drosophila melanogaster	53.47	0.00e+00	838.00
IUUC-Ete-032552	Echinops telfairi	93.43	0.00e+00	2987.00
IUUC-Eca-033457	Equus caballus	97.73	0.00e+00	6499.00
IUUC-Eeu-035118	Erinaceus europaeus	93.64	0.00e+00	3059.00
IUUC-Fca-036213	Felis catus	95.98	0.00e+00	5050.00
IUUC-Fal-037643	Ficedula albicollis	92.12	0.00e+00	6125.00
IUUC-Fox-037971	Fusarium oxysporum	26.95	2.00e-62	235.00
IUUC-Fso-038108	Fusarium solani	32.20	8.00e-59	223.00
IUUC-Ggr-040075	Gaeumannomyces graminis	32.63	6.00e-63	237.00
IUUC-Gga-040511	Gallus gallus	92.13	0.00e+00	6155.00
IUUC-Gac-042024	Gasterosteus aculeatus	87.31	0.00e+00	4947.00
IUUC-Ggo-044924	Gorilla gorilla	95.35	0.00e+00	6300.00
IUUC-Hsa-046913	Homo sapiens	99.05	0.00e+00	6574.00
IUUC-Itr-048626	Ictidomys tridecemlineatus	97.70	0.00e+00	6494.00
IUUC-Lch-049675	Latimeria chalumnae	86.62	0.00e+00	4656.00
IUUC-Loc-052832	Lepisosteus oculatus	87.22	0.00e+00	5729.00
IUUC-Lma-053130	Leptosphaeria maculans	27.55	3.00e-61	231.00
IUUC-Laf-054169	Loxodonta africana	96.13	0.00e+00	6436.00
IUUC-Mcc-055847	Macaca mulatta	97.93	0.00e+00	6448.00
IUUC-Meu-056327	Macropus eugenii	84.85	0.00e+00	1553.00
IUUC-Mor-057152	Magnaporthe oryzae	35.14	5.00e-62	234.00
IUUC-Mpo-057310	Magnaporthe poae	31.26	4.00e-60	228.00
IUUC-Mmr-060780	Microcebus murinus	98.08	0.00e+00	6518.00
IUUC-Mdo-062308	Monodelphis domestica	92.25	0.00e+00	6119.00
IUUC-Mmu-063457	Mus musculus	95.71	0.00e+00	6388.00
IUUC-Mpu-066917	Mustela putorius furo	95.57	0.00e+00	6295.00
IUUC-Mlu-067696	Myotis lucifugus	97.52	0.00e+00	6467.00
IUUC-Nfi-068259	Neosartorya fischeri	33.86	3.00e-63	238.00
IUUC-Ncr-068911	Neurospora crassa	25.31	3.00e-59	225.00
IUUC-Nle-069586	Nomascus leucogenys	98.85	0.00e+00	6592.00
IUUC-Opr-070447	Ochotona princeps	93.53	0.00e+00	2874.00
IUUC-Ont-072396	Oreochromis niloticus	85.64	0.00e+00	5301.00
IUUC-Oan-073147	Ornithorhynchus anatinus	94.42	0.00e+00	6303.00
IUUC-Ocu-074324	Oryctolagus cuniculus	97.52	0.00e+00	6464.00
IUUC-Ola-086312	Oryzias latipes	82.02	0.00e+00	5255.00
IUUC-Oga-088878	Otolemur garnettii	98.02	0.00e+00	6516.00
IUUC-Oar-089919	Ovis aries	97.53	0.00e+00	6447.00
IUUC-Ptr-090713	Pan troglodytes	98.81	0.00e+00	5994.00
IUUC-Pan-091957	Papio anubis	99.34	0.00e+00	5148.00
IUUC-Psi-093240	Pelodiscus sinensis	93.45	0.00e+00	6217.00
IUUC-Pma-094469	Petromyzon marinus	72.77	0.00e+00	4078.00
IUUC-Pno-095059	Phaeosphaeria nodorum	29.55	7.00e-58	220.00
IUUC-Pfo-097159	Poecilia formosa	83.64	0.00e+00	5340.00
IUUC-Pca-100799	Procavia capensis	90.54	0.00e+00	1932.00
IUUC-Pva-103226	Pteropus vampyrus	92.62	0.00e+00	6070.00
IUUC-Pte-104235	Pyrenophora teres	27.72	2.00e-59	225.00
IUUC-Pyt-104803	Pyrenophora triticirepentis	27.63	9.00e-61	229.00
IUUC-Rno-105389	Rattus norvegicus	96.06	0.00e+00	5526.00
IUUC-Sha-106979	Sarcophilus harrisii	94.20	0.00e+00	6267.00
IUUC-Sar-113444	Sorex araneus	90.55	0.00e+00	5938.00
IUUC-Ssc-115815	Sus scrofa	97.03	0.00e+00	5321.00
IUUC-Tgu-117470	Taeniopygia guttata	93.30	0.00e+00	6192.00
IUUC-Tru-118543	Takifugu rubripes	81.64	0.00e+00	5301.00
IUUC-Tsy-119081	Tarsius syrichta	88.86	0.00e+00	4878.00
IUUC-Tni-120294	Tetraodon nigroviridis	81.90	7.00e-165	573.00
IUUC-Tre-122057	Trichoderma reesei	29.73	9.00e-63	236.00
IUUC-Tvi-122570	Trichoderma virens	35.62	2.00e-59	226.00
IUUC-Tme-127154	Tuber melanosporum	27.72	9.00e-60	225.00
IUUC-Tbe-127801	Tupaia belangeri	86.50	0.00e+00	3311.00
IUUC-Ttr-129262	Tursiops truncatus	93.03	0.00e+00	6111.00
IUUC-Vda-129686	Verticillium dahliae	28.17	8.00e-62	233.00
IUUC-Vpa-130484	Vicugna pacos	95.66	0.00e+00	5271.00
IUUC-Xtr-131769	Xenopus tropicalis	86.16	0.00e+00	5789.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence