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Tag Content
UUCD2 ID IUUC-Aca-005170
UUCD1 version UUC-AnC-00495
Ensembl Protein ID ENSACAP00000002663.2
UniProt Accession G1KB43; G1KB43_ANOCA
Protein Name tRNA (guanine-N(7)-)-methyltransferase non-catalytic subunit WDR4; WD repeat-containing protein 4
Gene Name WDR4
Ensembl Information
Ensembl Gene ID Ensembl Transcript ID Ensembl Protein ID
ENSACAG00000002741.3 ENSACAT00000002730.3 ENSACAP00000002663.2
Status Unreviewed
Classification
Family E-Value Score Start End
E3 adaptor/Cullin RING/DCX/DWD 5.10e-06 26.6 188 224
Active Site
Position(s) Description Evidence
N/A N/A N/A
Domain Profile

   E3 adaptor/Cullin RING/DCX/DWD
   S: 1    gHtdsvtclaf..sd..tllvsGsdDgtikvWDlrtgv 34
           gHt+ v+ + f  ++  +ll+s+s+D+t+++W+++ g+
   Q: 188  GHTEFVSRI-FviPNypDLLLSASGDCTLRLWEYKHGK 224
           678878888.888444799**************98776 PP
   
Organism Anolis carolinensis
Functional Description
(View)

Functional Description


     Required for the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA. In the complex, it is required to stabilize and induce conformational changes of the catalytic subunit.
 Required for the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA. In the complex, it is required to stabilize and induce conformational changes of the catalytic subunit.
Protein Sequence
(Fasta)
RETPAGAGAP GGLLALTGGT RLLAARLKEP SHDDLFVYDC ATASKTPQEK QGKDIKSSGK 60
ASHDILACAF SSSGTYFSLT DDNKQLILFR TKPAWECLSI RSVIRRCTSL IITATEDKIL 120
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Protein Fasta Sequence


>IUUC-Aca-005170|E3,WD_repeat|Anolis carolinensis
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Nucleotide Sequence
(Fasta)
GCTCAATGCA GTCATGCCAG CCACATGACC TTGGAGGTGT CTACGGACAA CGCCGGCTCT 60
TCGGCTTAGA AATTGAGATG AGCACCAACC CCCAGAGTCG GACGCAACTA GACTTAATGT 120
It may take some time, please wait.

Nucleotide Fasta Sequence


>IUUC-Aca-005170|E3,WD_repeat|Anolis carolinensis
Please wait for a moment...
Sequence Source Ensembl
Keyword

KW-0181--Complete proteome
KW-0539--Nucleus
KW-1185--Reference proteome
KW-0677--Repeat
KW-0819--tRNA processing
KW-0853--WD repeat
Interpro

IPR028884--Trm82
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR017986--WD40_repeat_dom
PROSITE

PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION
SMART

SM00320--WD40
Gene Ontology

GO:0005829--C:cytosol
GO:0005654--C:nucleoplasm
GO:0005634--C:nucleus
GO:0043527--C:tRNA methyltransferase complex
GO:0008176--F:tRNA (guanine-N7-)-methyltransferase activity
Orthology
iUUCD ID Species Identity E-value Score
IUUC-Ata-000556 Aegilops tauschii 27.49 8.00e-09 54.70
IUUC-Atr-002431 Amborella trichopoda 41.18 9.00e-06 42.40
IUUC-Apl-003975 Anas platyrhynchos 65.85 5.00e-129 454.00
IUUC-Aly-005769 Arabidopsis lyrata 35.03 7.00e-16 78.20
IUUC-Ath-006733 Arabidopsis thaliana 35.03 9.00e-16 77.80
IUUC-Acl-008151 Aspergillus clavatus 46.38 9.00e-11 61.60
IUUC-Afl-008518 Aspergillus flavus 47.69 5.00e-11 61.60
IUUC-Afu-009102 Aspergillus fumigatus 34.86 8.00e-11 61.60
IUUC-Ani-009442 Aspergillus nidulans 40.54 2.00e-09 57.00
IUUC-Aor-010133 Aspergillus oryzae 47.69 5.00e-11 62.40
IUUC-Ate-010465 Aspergillus terreus 43.28 3.00e-10 59.70
IUUC-Ame-010613 Astyanax mexicanus 42.72 1.00e-81 296.00
IUUC-Bgr-012067 Blumeria graminis 35.34 9.00e-14 71.60
IUUC-Bta-012788 Bos taurus 53.53 3.00e-112 398.00
IUUC-Bdi-014458 Brachypodium distachyon 31.88 3.00e-12 66.20
IUUC-Bol-016398 Brassica oleracea 30.67 3.00e-18 86.30
IUUC-Bra-016644 Brassica rapa 35.12 1.00e-16 82.40
IUUC-Cpo-021963 Cavia porcellus 49.60 3.00e-97 348.00
IUUC-Csa-024148 Chlorocebus sabaeus 53.47 5.00e-96 344.00
IUUC-Cne-026834 Cryptococcus neoformans 38.19 8.00e-14 72.00
IUUC-Dre-028427 Danio rerio 45.39 2.00e-85 309.00
IUUC-Dno-028881 Dasypus novemcinctus 48.42 1.00e-102 366.00
IUUC-Dor-030522 Dipodomys ordii 51.03 1.00e-114 405.00
IUUC-Dme-032136 Drosophila melanogaster 34.62 2.00e-19 89.70
IUUC-Fca-035833 Felis catus 53.42 2.00e-107 382.00
IUUC-Fal-037497 Ficedula albicollis 68.64 7.00e-129 453.00
IUUC-Gga-040547 Gallus gallus 66.41 1.00e-131 462.00
IUUC-Gac-041761 Gasterosteus aculeatus 42.90 4.00e-73 268.00
IUUC-Gma-043722 Glycine max 35.47 2.00e-14 73.20
IUUC-Ggo-045340 Gorilla gorilla 52.72 3.00e-100 358.00
IUUC-Hsa-046403 Homo sapiens 52.72 7.00e-100 357.00
IUUC-Hvu-047643 Hordeum vulgare 30.65 2.00e-15 77.00
IUUC-Itr-048103 Ictidomys tridecemlineatus 52.62 2.00e-108 385.00
IUUC-Kpa-049283 Komagataella pastoris 26.40 1.00e-11 64.30
IUUC-Lch-050682 Latimeria chalumnae 51.51 8.00e-101 360.00
IUUC-Lpe-050712 Leersia perrieri 34.48 3.00e-19 89.40
IUUC-Loc-052599 Lepisosteus oculatus 53.05 5.00e-113 400.00
IUUC-Laf-054390 Loxodonta africana 53.41 1.00e-115 409.00
IUUC-Mcc-054747 Macaca mulatta 53.47 1.00e-99 356.00
IUUC-Mtr-058600 Medicago truncatula 30.90 1.00e-18 87.40
IUUC-Mla-059129 Melampsora laricipopulina 25.53 8.00e-10 57.40
IUUC-Mga-059876 Meleagris gallopavo 67.84 8.00e-133 466.00
IUUC-Mvi-060359 Microbotryum violaceum 28.40 2.00e-10 60.80
IUUC-Mmr-061518 Microcebus murinus 53.90 1.00e-108 385.00
IUUC-Mac-065625 Musa acuminata 30.43 2.00e-14 73.60
IUUC-Nfi-068402 Neosartorya fischeri 33.94 2.00e-10 60.10
IUUC-Nle-069914 Nomascus leucogenys 51.73 4.00e-93 334.00
IUUC-Ont-071555 Oreochromis niloticus 41.21 5.00e-71 261.00
IUUC-Oan-072951 Ornithorhynchus anatinus 60.79 4.00e-123 434.00
IUUC-Ocu-074679 Oryctolagus cuniculus 52.07 3.00e-99 355.00
IUUC-Obr-076769 Oryza brachyantha 32.37 8.00e-19 87.80
IUUC-Ogl-077168 Oryza glaberrima 30.71 3.00e-19 89.40
IUUC-Oin-079207 Oryza indica 30.71 3.00e-19 89.40
IUUC-Opu-084031 Oryza punctata 31.30 3.00e-20 93.20
IUUC-Osa-085327 Oryza sativa 34.24 5.00e-19 88.60
IUUC-Ola-086716 Oryzias latipes 38.46 6.00e-64 237.00
IUUC-Olu-087708 Ostreococcus lucimarinus 26.29 8.00e-11 61.20
IUUC-Oar-090239 Ovis aries 53.35 3.00e-107 381.00
IUUC-Ptr-090851 Pan troglodytes 52.72 1.00e-100 359.00
IUUC-Pan-092558 Papio anubis 51.97 2.00e-95 342.00
IUUC-Psi-093792 Pelodiscus sinensis 71.50 2.00e-153 535.00
IUUC-Ppa-095757 Physcomitrella patens 34.52 3.00e-15 76.30
IUUC-Pfo-096465 Poecilia formosa 40.77 7.00e-74 270.00
IUUC-Pab-097722 Pongo abelii 53.12 8.00e-104 370.00
IUUC-Pop-098979 Populus trichocarpa 31.55 3.00e-15 75.90
IUUC-Pca-100753 Procavia capensis 53.98 1.00e-72 266.00
IUUC-Sja-107780 Schizosaccharomyces japonicus 41.56 3.00e-10 59.70
IUUC-Spo-108251 Schizosaccharomyces pombe 25.00 3.00e-08 52.80
IUUC-Smo-108938 Selaginella moellendorffii 34.05 1.00e-16 80.50
IUUC-Sit-110020 Setaria italica 32.97 6.00e-17 81.60
IUUC-Sly-111543 Solanum lycopersicum 28.52 2.00e-17 83.20
IUUC-Stu-111925 Solanum tuberosum 28.52 3.00e-17 82.80
IUUC-Sbi-114061 Sorghum bicolor 29.84 1.00e-19 90.90
IUUC-Tgu-117321 Taeniopygia guttata 66.28 4.00e-121 427.00
IUUC-Tru-118454 Takifugu rubripes 39.04 6.00e-67 247.00
IUUC-Tni-119894 Tetraodon nigroviridis 38.52 1.00e-61 229.00
IUUC-Tca-121746 Theobroma cacao 30.45 8.00e-16 78.20
IUUC-Tae-124459 Triticum aestivum 30.00 8.00e-16 77.80
IUUC-Tur-126254 Triticum urartu 28.29 4.00e-10 58.90
IUUC-Tbe-127683 Tupaia belangeri 37.10 1.00e-36 147.00
IUUC-Ttr-129056 Tursiops truncatus 51.09 6.00e-101 360.00
IUUC-Vvi-131428 Vitis vinifera 33.15 1.00e-15 77.00
IUUC-Xma-133605 Xiphophorus maculatus 42.75 1.00e-77 283.00
Created Date 25-Jun-2017

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