iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Oan-073162

Ensembl Protein ID

ENSOANP00000015719.2

UniProt Accession

F6TM15; F6TM15_ORNAN

Protein Name

Uncharacterized protein

Gene Name

TBK1

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSOANG00000009917.3	ENSOANT00000015722.2	ENSOANP00000015719.2

Status

Unreviewed

Classification

Family	Identity	E-Value	Score	Source Orthology
ULD/UDP/UBQ/UBQ_Other	90.14	0.00e+00	1351.00	IUUC-Mmu-064107

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Organism

Ornithorhynchus anatinus

Protein Sequence
(Fasta)

KTGDLFAVKV FNSISFLRPM DVQMREFEVL KKLNHKNIVK LFAIEEETTT RHKVLVMEFC 60
PYGSLYTVLE EPSNAYGLPE SEFLIVLRDV VGGMNHLREN GIVHRDIKPG NIMRVIGEDG 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

AAAACAGGTG ACTTATTTGC CGTCAAAGTA TTCAATAGCA TAAGTTTTCT TCGCCCCATG 60
GACGTTCAGA TGAGAGAGTT TGAAGTGCTA AAGAAACTGA ATCACAAAAA CATTGTCAAA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR011009--Kinase-like_dom
IPR000719--Prot_kinase_dom

PROSITE

PS50011--PROTEIN_KINASE_DOM

Pfam

PF00069--Pkinase

SMART

SM00220--S_TKc

Gene Ontology

GO:0005737--C:cytoplasm
GO:0005524--F:ATP binding
GO:0003676--F:nucleic acid binding
GO:0004674--F:protein serine/threonine kinase activity
GO:0002218--P:activation of innate immune response
GO:0050830--P:defense response to Gram-positive bacterium
GO:0044565--P:dendritic cell proliferation
GO:0045087--P:innate immune response
GO:0010629--P:negative regulation of gene expression
GO:0018105--P:peptidyl-serine phosphorylation
GO:0018107--P:peptidyl-threonine phosphorylation
GO:0043123--P:positive regulation of I-kappaB kinase/NF-kappaB signaling
GO:0032727--P:positive regulation of interferon-alpha production
GO:0045359--P:positive regulation of interferon-beta biosynthetic process
GO:0045944--P:positive regulation of transcription from RNA polymerase II promoter
GO:1904417--P:positive regulation of xenophagy

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001638	Ailuropoda melanoleuca	91.86	0.00e+00	1372.00
IUUC-Apl-004028	Anas platyrhynchos	86.57	0.00e+00	1292.00
IUUC-Aca-004998	Anolis carolinensis	82.00	0.00e+00	1226.00
IUUC-Ame-011617	Astyanax mexicanus	70.11	0.00e+00	1013.00
IUUC-Bta-012799	Bos taurus	91.57	0.00e+00	1370.00
IUUC-Cja-019357	Callithrix jacchus	91.30	0.00e+00	1365.00
IUUC-Cfa-020309	Canis familiaris	91.14	0.00e+00	1365.00
IUUC-Cpo-022062	Cavia porcellus	91.29	0.00e+00	1359.00
IUUC-Csa-023517	Chlorocebus sabaeus	91.57	0.00e+00	1370.00
IUUC-Cho-025037	Choloepus hoffmanni	88.69	0.00e+00	941.00
IUUC-Cin-025580	Ciona intestinalis	39.58	7.00e-140	490.00
IUUC-Csv-025818	Ciona savignyi	39.13	9.00e-135	473.00
IUUC-Dre-027527	Danio rerio	70.53	0.00e+00	1021.00
IUUC-Dno-029475	Dasypus novemcinctus	81.80	0.00e+00	1089.00
IUUC-Dme-031698	Drosophila melanogaster	39.77	1.00e-123	436.00
IUUC-Ete-033090	Echinops telfairi	78.29	0.00e+00	1126.00
IUUC-Eca-033996	Equus caballus	91.00	0.00e+00	1360.00
IUUC-Eeu-035082	Erinaceus europaeus	82.64	0.00e+00	825.00
IUUC-Fca-035921	Felis catus	88.95	0.00e+00	1311.00
IUUC-Fal-037406	Ficedula albicollis	87.00	0.00e+00	1298.00
IUUC-Gmo-038721	Gadus morhua	69.77	0.00e+00	988.00
IUUC-Gga-041234	Gallus gallus	85.71	0.00e+00	1287.00
IUUC-Gac-042315	Gasterosteus aculeatus	70.98	0.00e+00	1012.00
IUUC-Ggo-044885	Gorilla gorilla	84.71	0.00e+00	1256.00
IUUC-Hsa-046847	Homo sapiens	91.14	0.00e+00	1367.00
IUUC-Itr-047906	Ictidomys tridecemlineatus	89.94	0.00e+00	1347.00
IUUC-Lch-049731	Latimeria chalumnae	53.43	0.00e+00	722.00
IUUC-Loc-051879	Lepisosteus oculatus	72.68	0.00e+00	1056.00
IUUC-Laf-054232	Loxodonta africana	90.87	0.00e+00	1357.00
IUUC-Mcc-055447	Macaca mulatta	91.71	0.00e+00	1373.00
IUUC-Meu-056138	Macropus eugenii	95.03	5.00e-176	610.00
IUUC-Mga-059460	Meleagris gallopavo	84.76	0.00e+00	1258.00
IUUC-Mmr-061445	Microcebus murinus	91.43	0.00e+00	1365.00
IUUC-Mmu-064107	Mus musculus	90.14	0.00e+00	1325.00
IUUC-Mpu-066834	Mustela putorius furo	92.00	0.00e+00	1373.00
IUUC-Mlu-068006	Myotis lucifugus	88.16	0.00e+00	1293.00
IUUC-Nle-069280	Nomascus leucogenys	91.00	0.00e+00	1365.00
IUUC-Opr-070728	Ochotona princeps	83.77	0.00e+00	1149.00
IUUC-Ont-071621	Oreochromis niloticus	72.04	0.00e+00	1028.00
IUUC-Ocu-074787	Oryctolagus cuniculus	91.16	0.00e+00	1365.00
IUUC-Ola-086737	Oryzias latipes	34.27	2.00e-24	107.00
IUUC-Oga-088764	Otolemur garnettii	90.71	0.00e+00	1355.00
IUUC-Oar-090333	Ovis aries	91.44	0.00e+00	1364.00
IUUC-Ptr-090568	Pan troglodytes	90.86	0.00e+00	1363.00
IUUC-Pan-091979	Papio anubis	91.58	0.00e+00	1368.00
IUUC-Psi-093336	Pelodiscus sinensis	86.86	0.00e+00	1284.00
IUUC-Pma-094200	Petromyzon marinus	43.13	2.00e-163	568.00
IUUC-Pfo-096354	Poecilia formosa	70.83	0.00e+00	1020.00
IUUC-Pab-098499	Pongo abelii	91.29	0.00e+00	1367.00
IUUC-Pva-102454	Pteropus vampyrus	89.57	0.00e+00	1322.00
IUUC-Rno-105595	Rattus norvegicus	89.57	0.00e+00	1315.00
IUUC-Sha-106864	Sarcophilus harrisii	91.75	0.00e+00	1366.00
IUUC-Sar-113728	Sorex araneus	82.86	0.00e+00	1208.00
IUUC-Tgu-117200	Taeniopygia guttata	85.21	0.00e+00	1277.00
IUUC-Tsy-119017	Tarsius syrichta	90.99	0.00e+00	1047.00
IUUC-Tni-120724	Tetraodon nigroviridis	70.44	0.00e+00	1014.00
IUUC-Tbe-127887	Tupaia belangeri	81.15	0.00e+00	939.00
IUUC-Ttr-129111	Tursiops truncatus	84.14	0.00e+00	1237.00
IUUC-Vpa-130724	Vicugna pacos	91.86	0.00e+00	1372.00
IUUC-Xtr-132091	Xenopus tropicalis	73.93	0.00e+00	1103.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence