iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Mac-064636

Ensembl Protein ID

GSMUA_Achr2P15850_001

UniProt Accession

M0S8C6; M0S8C6_MUSAM

Protein Name

Coatomer subunit beta'

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
GSMUA_Achr2G15850_001	GSMUA_Achr2T15850_001	GSMUA_Achr2P15850_001

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	8.70e-35	118.1	209	249
UBD/Beta-Prp	4.10e-65	220.8	30	314

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 2    Htdsvtclaf...sd.tllvsGsdDgtikvWDlrtgvllks 38
           H+ +v+c+++    d ++l++GsdD t kvWD+ t  ++++
   Q: 209  HSKGVNCVDYftgGDrPYLITGSDDQTAKVWDYQTKSCVQT 249
           999*****966*9778*******************999986 PP

UBD/Beta-Prp

   S: 9    hksvitcvkfspdksllatgsrdgtikvwdvttgkl.........lrslsgheaevtavkfspdgkilvtgseDrtikvwdlstgkcv 87
           +++++++v+ +p +++++++ ++g++ +w+++t+ +         ++s++  e +v++ kf+ ++++ v g++D++i+v++++t + +
   Q: 30   RSERVKSVDLHPTEPWILASLYSGSVCIWNYQTQAMlptclwttmVKSFEVTELPVRSAKFIARKQWVVAGADDMFIRVYNYNTMDKI 117
           5678999********************************************************************************* PP
   S: 88   htlkghedsvlslsfspsgdklvsGshdrtirvwdletgqcleetlsghdgvvncvvvhpdg.nllvsGslDrtvrlWdlktgkllrt 174
            ++++h+d++++++++p+  +++s s+d  i++wd+e+g+   ++++gh++ v+ vv++p++ n ++s+slDrt+++W+l + +   t
   Q: 118  KVFEAHTDYIRCVAIHPTLPYVLSSSDDMLIKLWDWEKGWMCTQIFEGHSHYVMQVVFNPKDtNTFASASLDRTIKIWNLGSPDPNFT 205
           ****************************************9999******************************************** PP
   S: 175  ltgghtdsvysls..fdsngkelvsgsldgtvklwdlqtgecvrtlnghtdnvksvrfspnderlvsgssDgsiriWdlrsgdllktl 260
           l   h + v++++     ++++l++gs+d+t k+wd+qt++cv+tl+ght nv+ v f+p+  ++++gs+Dg++r+W  ++  l +tl
   Q: 206  LDA-HSKGVNCVDyfTGGDRPYLITGSDDQTAKVWDYQTKSCVQTLEGHTHNVSAVCFHPELPIILTGSEDGTVRVWHATTYRLENTL 292
           *98.*********7445566******************************************************************** PP
   S: 261  qlhnssvisvavlsfgdnvlvl 282
           ++  ++v++v +++ +++v++ 
   Q: 293  NYGLERVWAVGYIKGSRRVVIG 314
           **********997777766654 PP

Organism

Musa acuminata

Functional Description
(View)

The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin-coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. Coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins.

Protein Sequence
(Fasta)

MLSSHNIQSP CRNLGKMPLR LDIKRKLAQR SERVKSVDLH PTEPWILASL YSGSVCIWNY 60
QTQAMLPTCL WTTMVKSFEV TELPVRSAKF IARKQWVVAG ADDMFIRVYN YNTMDKIKVF 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGTTATCTT CTCACAACAT TCAATCTCCT TGTCGTAATG TCTGATCTTC TTAGCCCGAT 60
GCTCGAATTT ACGGACCGAA GCCTTCTGTC GACACGTCGA CCGATCCTTC AACCCGACAT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0963--Cytoplasm
KW-0968--Cytoplasmic vesicle
KW-0931--ER-Golgi transport
KW-0333--Golgi apparatus
KW-0472--Membrane
KW-0653--Protein transport
KW-1185--Reference proteome
KW-0813--Transport
KW-0853--WD repeat

Interpro

IPR006692--Coatomer_WD-assoc_reg
IPR016453--COPB2
IPR020472--G-protein_beta_WD-40_rep
IPR011990--TPR-like_helical_dom
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR017986--WD40_repeat_dom

PROSITE

PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF04053--Coatomer_WDAD
PF00400--WD40

PRINTS

PR00320--GPROTEINBRPT

SMART

SM00320--WD40

Gene Ontology

GO:0030663--C:COPI-coated vesicle membrane
GO:0000139--C:Golgi membrane
GO:0030117--C:membrane coat
GO:0005198--F:structural molecule activity
GO:0006886--P:intracellular protein transport
GO:0016192--P:vesicle-mediated transport

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000654	Aegilops tauschii	74.84	0.00e+00	1409.00
IUUC-Aml-002154	Ailuropoda melanoleuca	60.02	0.00e+00	1104.00
IUUC-Atr-003090	Amborella trichopoda	81.18	0.00e+00	1533.00
IUUC-Apl-003976	Anas platyrhynchos	60.02	0.00e+00	1107.00
IUUC-Aca-004301	Anolis carolinensis	59.91	0.00e+00	1109.00
IUUC-Aly-006508	Arabidopsis lyrata	81.08	0.00e+00	1529.00
IUUC-Ath-007630	Arabidopsis thaliana	80.56	0.00e+00	1521.00
IUUC-Ago-007914	Ashbya gossypii	46.44	0.00e+00	723.00
IUUC-Acl-008237	Aspergillus clavatus	52.29	0.00e+00	904.00
IUUC-Afu-008845	Aspergillus fumigatus	51.27	0.00e+00	893.00
IUUC-Ani-009135	Aspergillus nidulans	54.79	0.00e+00	892.00
IUUC-Ang-009654	Aspergillus niger	55.13	0.00e+00	811.00
IUUC-Aor-009939	Aspergillus oryzae	51.18	0.00e+00	913.00
IUUC-Ate-010355	Aspergillus terreus	51.49	0.00e+00	879.00
IUUC-Ame-010922	Astyanax mexicanus	53.53	0.00e+00	954.00
IUUC-Bgr-012249	Blumeria graminis	52.64	0.00e+00	894.00
IUUC-Bta-013579	Bos taurus	61.19	0.00e+00	978.00
IUUC-Bci-013866	Botrytis cinerea	52.86	0.00e+00	885.00
IUUC-Bdi-015046	Brachypodium distachyon	81.84	0.00e+00	1547.00
IUUC-Bol-016271	Brassica oleracea	79.89	0.00e+00	1523.00
IUUC-Bra-017758	Brassica rapa	80.07	0.00e+00	1516.00
IUUC-Cel-018387	Caenorhabditis elegans	52.63	0.00e+00	967.00
IUUC-Cja-019145	Callithrix jacchus	59.95	0.00e+00	1105.00
IUUC-Cfa-020564	Canis familiaris	60.07	0.00e+00	1107.00
IUUC-Cpo-022201	Cavia porcellus	60.02	0.00e+00	1106.00
IUUC-Cre-022938	Chlamydomonas reinhardtii	66.15	0.00e+00	1120.00
IUUC-Csa-023383	Chlorocebus sabaeus	64.42	0.00e+00	832.00
IUUC-Cho-024454	Choloepus hoffmanni	58.45	0.00e+00	939.00
IUUC-Cin-025681	Ciona intestinalis	59.22	0.00e+00	993.00
IUUC-Csv-026012	Ciona savignyi	58.05	0.00e+00	972.00
IUUC-Cgl-026649	Colletotrichum gloeosporioides	47.62	0.00e+00	783.00
IUUC-Cne-026986	Cryptococcus neoformans	50.25	0.00e+00	857.00
IUUC-Cme-027219	Cyanidioschyzon merolae	48.16	0.00e+00	892.00
IUUC-Dre-027846	Danio rerio	60.89	0.00e+00	1107.00
IUUC-Dor-030462	Dipodomys ordii	58.88	0.00e+00	853.00
IUUC-Dse-031268	Dothistroma septosporum	51.75	0.00e+00	890.00
IUUC-Dme-031791	Drosophila melanogaster	56.42	0.00e+00	995.00
IUUC-Ete-033166	Echinops telfairi	57.29	0.00e+00	699.00
IUUC-Eca-034180	Equus caballus	58.55	0.00e+00	1066.00
IUUC-Fca-036265	Felis catus	59.82	0.00e+00	1110.00
IUUC-Fal-037202	Ficedula albicollis	59.27	0.00e+00	1056.00
IUUC-Fox-037711	Fusarium oxysporum	52.13	0.00e+00	839.00
IUUC-Fso-038268	Fusarium solani	51.14	0.00e+00	845.00
IUUC-Gmo-039046	Gadus morhua	59.18	0.00e+00	1092.00
IUUC-Ggr-039863	Gaeumannomyces graminis	51.46	0.00e+00	859.00
IUUC-Gga-041112	Gallus gallus	60.66	0.00e+00	1117.00
IUUC-Gac-041733	Gasterosteus aculeatus	58.93	0.00e+00	1070.00
IUUC-Gma-042910	Glycine max	85.46	0.00e+00	1620.00
IUUC-Ggo-044984	Gorilla gorilla	59.95	0.00e+00	1105.00
IUUC-Hsa-046698	Homo sapiens	59.95	0.00e+00	1105.00
IUUC-Hvu-047669	Hordeum vulgare	90.08	0.00e+00	700.00
IUUC-Itr-048212	Ictidomys tridecemlineatus	59.91	0.00e+00	1101.00
IUUC-Kpa-049265	Komagataella pastoris	51.48	0.00e+00	850.00
IUUC-Lch-050473	Latimeria chalumnae	60.12	0.00e+00	1107.00
IUUC-Lpe-051579	Leersia perrieri	83.44	0.00e+00	1536.00
IUUC-Loc-052675	Lepisosteus oculatus	59.54	0.00e+00	1109.00
IUUC-Lma-053218	Leptosphaeria maculans	52.81	0.00e+00	870.00
IUUC-Laf-053757	Loxodonta africana	60.00	0.00e+00	1100.00
IUUC-Mcc-054859	Macaca mulatta	59.95	0.00e+00	1105.00
IUUC-Mor-057264	Magnaporthe oryzae	51.94	0.00e+00	862.00
IUUC-Mpo-057538	Magnaporthe poae	51.22	0.00e+00	864.00
IUUC-Mtr-058618	Medicago truncatula	83.62	0.00e+00	1554.00
IUUC-Mla-058937	Melampsora laricipopulina	52.09	0.00e+00	897.00
IUUC-Mga-059875	Meleagris gallopavo	60.51	0.00e+00	1112.00
IUUC-Mvi-060240	Microbotryum violaceum	51.27	0.00e+00	905.00
IUUC-Mmr-061261	Microcebus murinus	60.07	0.00e+00	1107.00
IUUC-Mdo-062076	Monodelphis domestica	60.30	0.00e+00	1113.00
IUUC-Mmu-063324	Mus musculus	60.07	0.00e+00	1108.00
IUUC-Mpu-065961	Mustela putorius furo	60.07	0.00e+00	1105.00
IUUC-Mlu-067059	Myotis lucifugus	59.60	0.00e+00	1075.00
IUUC-Nfi-068277	Neosartorya fischeri	51.72	0.00e+00	886.00
IUUC-Ncr-068659	Neurospora crassa	51.28	0.00e+00	891.00
IUUC-Nle-069034	Nomascus leucogenys	59.95	0.00e+00	1105.00
IUUC-Opr-070334	Ochotona princeps	62.06	0.00e+00	1014.00
IUUC-Ont-071563	Oreochromis niloticus	59.63	0.00e+00	1107.00
IUUC-Oan-073416	Ornithorhynchus anatinus	59.27	0.00e+00	1045.00
IUUC-Ocu-074522	Oryctolagus cuniculus	59.95	0.00e+00	1101.00
IUUC-Oba-075760	Oryza barthii	81.68	0.00e+00	1533.00
IUUC-Obr-076201	Oryza brachyantha	83.97	0.00e+00	1569.00
IUUC-Ogl-077450	Oryza glaberrima	82.55	0.00e+00	1558.00
IUUC-Ogu-078994	Oryza glumaepatula	81.68	0.00e+00	1529.00
IUUC-Oin-079211	Oryza indica	80.61	0.00e+00	1514.00
IUUC-Olo-080731	Oryza longistaminata	80.65	0.00e+00	1509.00
IUUC-Ome-081762	Oryza meridionalis	76.06	0.00e+00	1426.00
IUUC-Oni-082324	Oryza nivara	81.68	0.00e+00	1530.00
IUUC-Opu-083400	Oryza punctata	81.29	0.00e+00	1542.00
IUUC-Oru-084829	Oryza rufipogon	81.68	0.00e+00	1531.00
IUUC-Osa-086026	Oryza sativa	82.77	0.00e+00	1570.00
IUUC-Ola-087245	Oryzias latipes	58.93	0.00e+00	1100.00
IUUC-Olu-087655	Ostreococcus lucimarinus	65.36	0.00e+00	1145.00
IUUC-Oga-088163	Otolemur garnettii	57.73	0.00e+00	1048.00
IUUC-Oar-089842	Ovis aries	59.44	0.00e+00	1104.00
IUUC-Ptr-090501	Pan troglodytes	59.95	0.00e+00	1105.00
IUUC-Pan-092011	Papio anubis	59.95	0.00e+00	1106.00
IUUC-Psi-093308	Pelodiscus sinensis	60.19	0.00e+00	1110.00
IUUC-Pma-094695	Petromyzon marinus	58.48	0.00e+00	985.00
IUUC-Ppa-095911	Physcomitrella patens	78.80	0.00e+00	1434.00
IUUC-Pfo-096587	Poecilia formosa	59.10	0.00e+00	1106.00
IUUC-Pab-097926	Pongo abelii	58.91	0.00e+00	1038.00
IUUC-Pop-099634	Populus trichocarpa	84.57	0.00e+00	1578.00
IUUC-Pca-100965	Procavia capensis	58.97	0.00e+00	1071.00
IUUC-Ppe-101470	Prunus persica	84.32	0.00e+00	1602.00
IUUC-Pva-102451	Pteropus vampyrus	57.54	0.00e+00	843.00
IUUC-Pgr-103453	Puccinia graminis	51.25	0.00e+00	910.00
IUUC-Ptt-103868	Puccinia triticina	51.63	0.00e+00	905.00
IUUC-Pte-104274	Pyrenophora teres	52.78	0.00e+00	906.00
IUUC-Pyt-104794	Pyrenophora triticirepentis	50.60	0.00e+00	855.00
IUUC-Rno-105979	Rattus norvegicus	53.01	0.00e+00	819.00
IUUC-Sce-106269	Saccharomyces cerevisiae	46.23	0.00e+00	751.00
IUUC-Sha-106905	Sarcophilus harrisii	60.30	0.00e+00	1111.00
IUUC-Sja-107838	Schizosaccharomyces japonicus	46.51	0.00e+00	782.00
IUUC-Spo-108299	Schizosaccharomyces pombe	46.47	0.00e+00	792.00
IUUC-Smo-108695	Selaginella moellendorffii	79.76	0.00e+00	1384.00
IUUC-Sit-110239	Setaria italica	84.18	0.00e+00	1583.00
IUUC-Sly-111211	Solanum lycopersicum	81.09	0.00e+00	1486.00
IUUC-Sbi-113801	Sorghum bicolor	81.92	0.00e+00	1547.00
IUUC-Sre-115040	Sporisorium reilianum	50.78	0.00e+00	888.00
IUUC-Ssc-115593	Sus scrofa	59.95	0.00e+00	1105.00
IUUC-Tgu-117239	Taeniopygia guttata	60.26	0.00e+00	1110.00
IUUC-Tru-118025	Takifugu rubripes	59.38	0.00e+00	1107.00
IUUC-Tsy-118824	Tarsius syrichta	57.43	0.00e+00	786.00
IUUC-Tni-120142	Tetraodon nigroviridis	60.72	0.00e+00	1097.00
IUUC-Tca-121613	Theobroma cacao	86.04	0.00e+00	1629.00
IUUC-Tre-122072	Trichoderma reesei	51.58	0.00e+00	885.00
IUUC-Tvi-122546	Trichoderma virens	50.61	0.00e+00	868.00
IUUC-Tae-125292	Triticum aestivum	83.48	0.00e+00	1568.00
IUUC-Tur-126283	Triticum urartu	75.58	0.00e+00	1406.00
IUUC-Tme-127041	Tuber melanosporum	52.55	0.00e+00	913.00
IUUC-Tbe-127770	Tupaia belangeri	60.09	0.00e+00	888.00
IUUC-Ttr-129294	Tursiops truncatus	59.84	0.00e+00	1103.00
IUUC-Uma-129351	Ustilago maydis	49.46	0.00e+00	880.00
IUUC-Vda-129716	Verticillium dahliae	52.13	0.00e+00	905.00
IUUC-Vvi-131689	Vitis vinifera	87.51	0.00e+00	1587.00
IUUC-Xtr-132633	Xenopus tropicalis	59.65	0.00e+00	1111.00
IUUC-Xma-133347	Xiphophorus maculatus	59.33	0.00e+00	1107.00
IUUC-Yli-134455	Yarrowia lipolytica	50.06	0.00e+00	816.00
IUUC-Zma-135706	Zea mays	82.79	0.00e+00	1566.00

Created Date

25-Jun-2017

Functional Description

Protein Fasta Sequence

Nucleotide Fasta Sequence