iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Mlu-067375

Ensembl Protein ID

ENSMLUP00000007384.2

UniProt Accession

G1PAQ2; G1PAQ2_MYOLU

Genbank Protein ID

ENSMLUP00000007384

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AAPE02001532

Gene Name

ARHGAP10

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSMLUG00000008067.2	ENSMLUT00000008085.2	ENSMLUP00000007384.2

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
UBD/SH3	2.70e-11	43.3	673	727

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

UBD/SH3

   S: 4    ekvqvlydyeaqnddeLtlkkGdvvlviekeeqdegWlkgvkelegkrGlfPenFvek 61
           +k ++ y+ ea+++ eL+++ G + + + +++ + gWl+g  +l+gkrGl+P+n+v+ 
   Q: 673  RKARAVYPCEAEHSSELSFEIGAIFEDV-QTSREPGWLEG--TLNGKRGLIPQNYVKL 727
           57899***********************.***********..8*************85 PP

Organism

Myotis lucifugus

Protein Sequence
(Fasta)

LSAAQRKFAH SLRDFKFEFI GDAETDDERC IDASLREFSN FLKNLEEQRE IMALSVTETL 60
IKPLEKFRKE QLGAVKEEKK KFDKETEKNY SLIDKHLNLS AKKKDSHLQE ADVQVEQNRQ 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CTTTCGGCAG CTCAGCGGAA GTTTGCTCAC TCGCTCAGAG ACTTTAAGTT TGAGTTCATT 60
GGCGATGCGG AGACCGATGA TGAACGCTGC ATAGGTACGT GAAGGGGAGG GTTTGGTCTG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR027267--AH/BAR-dom
IPR011993--PH_dom-like
IPR001849--PH_domain
IPR008936--Rho_GTPase_activation_prot
IPR000198--RhoGAP_dom
IPR001452--SH3_domain

PROSITE

PS50003--PH_DOMAIN
PS50238--RHOGAP
PS50002--SH3

Pfam

PF00169--PH
PF00620--RhoGAP
PF14604--SH3_9

SMART

SM00233--PH
SM00324--RhoGAP
SM00326--SH3

Gene Ontology

GO:0005829--C:cytosol
GO:0005096--F:GTPase activator activity
GO:0007010--P:cytoskeleton organization
GO:0043066--P:negative regulation of apoptotic process
GO:0007165--P:signal transduction

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001253	Ailuropoda melanoleuca	92.51	0.00e+00	1324.00
IUUC-Apl-003297	Anas platyrhynchos	79.18	0.00e+00	1127.00
IUUC-Aca-005285	Anolis carolinensis	77.25	0.00e+00	1117.00
IUUC-Ame-011422	Astyanax mexicanus	59.43	7.00e-179	620.00
IUUC-Bta-012379	Bos taurus	91.27	0.00e+00	1257.00
IUUC-Cel-018542	Caenorhabditis elegans	39.45	4.00e-112	399.00
IUUC-Cja-019182	Callithrix jacchus	91.14	0.00e+00	1304.00
IUUC-Cfa-021141	Canis familiaris	92.51	0.00e+00	1315.00
IUUC-Cpo-021338	Cavia porcellus	64.45	0.00e+00	679.00
IUUC-Csa-023847	Chlorocebus sabaeus	92.37	0.00e+00	1306.00
IUUC-Cin-025725	Ciona intestinalis	39.25	5.00e-129	455.00
IUUC-Dre-027525	Danio rerio	59.57	0.00e+00	800.00
IUUC-Dno-029215	Dasypus novemcinctus	86.74	0.00e+00	908.00
IUUC-Dor-030308	Dipodomys ordii	81.88	0.00e+00	1135.00
IUUC-Dme-032147	Drosophila melanogaster	42.14	2.00e-115	410.00
IUUC-Ete-032666	Echinops telfairi	80.51	0.00e+00	763.00
IUUC-Eca-033545	Equus caballus	93.32	0.00e+00	1323.00
IUUC-Fca-036457	Felis catus	92.64	0.00e+00	1320.00
IUUC-Fal-036703	Ficedula albicollis	79.38	0.00e+00	1128.00
IUUC-Gga-040830	Gallus gallus	77.85	0.00e+00	1126.00
IUUC-Gac-041728	Gasterosteus aculeatus	55.10	0.00e+00	744.00
IUUC-Ggo-044569	Gorilla gorilla	89.92	0.00e+00	1256.00
IUUC-Hsa-045658	Homo sapiens	92.23	0.00e+00	1271.00
IUUC-Lch-050300	Latimeria chalumnae	63.06	0.00e+00	664.00
IUUC-Loc-051740	Lepisosteus oculatus	63.30	0.00e+00	895.00
IUUC-Laf-053641	Loxodonta africana	91.14	0.00e+00	1261.00
IUUC-Mcc-055152	Macaca mulatta	92.10	0.00e+00	1317.00
IUUC-Meu-056107	Macropus eugenii	54.36	9.00e-156	544.00
IUUC-Mga-059914	Meleagris gallopavo	61.19	0.00e+00	641.00
IUUC-Mmr-061434	Microcebus murinus	93.32	0.00e+00	1340.00
IUUC-Mdo-062864	Monodelphis domestica	86.78	0.00e+00	1248.00
IUUC-Mmu-064061	Mus musculus	89.51	0.00e+00	1293.00
IUUC-Nle-069319	Nomascus leucogenys	87.78	0.00e+00	699.00
IUUC-Ont-071443	Oreochromis niloticus	60.38	0.00e+00	828.00
IUUC-Oan-072978	Ornithorhynchus anatinus	83.55	0.00e+00	1096.00
IUUC-Ocu-074591	Oryctolagus cuniculus	86.78	0.00e+00	1232.00
IUUC-Ola-087508	Oryzias latipes	62.66	0.00e+00	692.00
IUUC-Oga-088922	Otolemur garnettii	87.00	4.00e-179	620.00
IUUC-Oar-089531	Ovis aries	91.27	0.00e+00	1273.00
IUUC-Ptr-091149	Pan troglodytes	90.87	0.00e+00	1264.00
IUUC-Pan-092591	Papio anubis	92.37	0.00e+00	1332.00
IUUC-Psi-093144	Pelodiscus sinensis	63.11	0.00e+00	694.00
IUUC-Pma-094731	Petromyzon marinus	31.76	3.00e-19	91.30
IUUC-Pfo-097265	Poecilia formosa	58.94	0.00e+00	814.00
IUUC-Pab-097780	Pongo abelii	91.83	0.00e+00	1270.00
IUUC-Rno-104991	Rattus norvegicus	89.10	0.00e+00	1291.00
IUUC-Sha-107629	Sarcophilus harrisii	83.97	0.00e+00	1096.00
IUUC-Ssc-115511	Sus scrofa	77.11	0.00e+00	717.00
IUUC-Tgu-117458	Taeniopygia guttata	78.37	0.00e+00	1111.00
IUUC-Tru-117724	Takifugu rubripes	61.47	0.00e+00	682.00
IUUC-Tni-119893	Tetraodon nigroviridis	59.13	2.00e-145	509.00
IUUC-Tbe-128126	Tupaia belangeri	25.56	5.00e-06	46.60
IUUC-Ttr-129045	Tursiops truncatus	89.37	0.00e+00	1241.00
IUUC-Xtr-132112	Xenopus tropicalis	68.95	0.00e+00	986.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence