iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Tgu-116988

UUCD1 version

Ensembl Protein ID

UniProt Accession

Genbank Protein ID

Protein Name

Eukaryotic translation initiation factor 3 subunit I; Eukaryotic translation initiation factor 3 subunit 2; eIF-3-beta; eIF3 p36

Genbank Nucleotide ID

ABQF01049668

Gene Name

EIF3I; EIF3S2

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSTGUG00000001395.1	ENSTGUT00000001466.1	ENSTGUP00000001453.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	1.00e-21	75.9	49	86
UBD/Beta-Prp	1.00e-43	149.4	5	232

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 1    gHtdsvtcl..afsd.tllvsGsdDgtikvWDlrtgvll 36
           gHt+ v+c+  ++ d +++++Gs D+++++WD  tg++l
   Q: 49   GHTGAVWCVdaDW-DtRHVLTGSADNSCRLWDCETGKQL 86
           8*******98679.559******************9986 PP

UBD/Beta-Prp

   S: 48   lsgheaevtavkfspdgkilvtgseDrtikvwdlstgkcvhtlkghedsvlslsfspsgdklvsGshdrtirvwdletgqcleetlsgh 136
           l+ghe  +t++k++++g++l t+++D +++vw   +g+ + t++gh+  v++++ + ++ ++++Gs+d+  r+wd etg+ l   l ++
   Q: 5    LQGHERSITQIKYNREGDLLFTVAKDPIVNVWYSVNGERLGTYNGHTGAVWCVDADWDTRHVLTGSADNSCRLWDCETGKQLA--LVKT 91
           69********************************************************************************7..8888 PP
   S: 137  dgvvncvvvhpdgnllvsGslDr.....tvrlWdlktgkllrtl......tgghtdsvyslsfdsngkelvsgsldgtvklwdlqtgec 214
           +++v++  ++  gn+++ +++ +     +v ++dl+  + ++            +++++s  + + g+++++g ++g ++ ++ ++ge 
   Q: 92   SSAVRTCGFDFGGNIIMFSTDKQmgyqcFVSFFDLRDPSQIENNepymkiPC-SDSKITSAVWGPLGEFIIAGHENGELNQFSAKSGEQ 179
           8888888888888888887654422222699999988888888866666433.6899******************************** PP
   S: 215  vrtlnghtdnvksvrfspnderlvsgssDgsiriWdlrsgdllktlqlhn..s 265
           +   ++ht++++++++s++ + ++++s+D++ +++d++s + lkt+  ++  +
   Q: 180  LSNIKEHTKQINDIQTSRDMTMFITASKDNTAKLFDCTSLKHLKTFRTERpvN 232
           **********************************************9977432 PP

Organism

Taeniopygia guttata

Functional Description
(View)

Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation.

Protein Sequence
(Fasta)

KPILLQGHER SITQIKYNRE GDLLFTVAKD PIVNVWYSVN GERLGTYNGH TGAVWCVDAD 60
WDTRHVLTGS ADNSCRLWDC ETGKQLALVK TSSAVRTCGF DFGGNIIMFS TDKQMGYQCF 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GCGTTTCCGC CATCTTCCCG GAAGTGCATC TCCCCCTCAC GCCTCAGCGC GGCCGCCATG 60
GTGAGACCGG GGTGGCCGCG GGCTCGTTGC TGGCGATTTT TAGTCGCCAC CGCTGATTTA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0963--Cytoplasm
KW-0396--Initiation factor
KW-0648--Protein biosynthesis
KW-1185--Reference proteome
KW-0677--Repeat
KW-0853--WD repeat

Interpro

IPR027525--eIF3i
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF00400--WD40

SMART

SM00320--WD40

Gene Ontology

GO:0016282--C:eukaryotic 43S preinitiation complex
GO:0033290--C:eukaryotic 48S preinitiation complex
GO:0071541--C:eukaryotic translation initiation factor 3 complex, eIF3m
GO:0070062--C:extracellular exosome
GO:0003743--F:translation initiation factor activity
GO:0001731--P:formation of translation preinitiation complex
GO:0006446--P:regulation of translational initiation

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000115	Aegilops tauschii	57.52	6.00e-35	140.00
IUUC-Aml-001321	Ailuropoda melanoleuca	92.90	0.00e+00	639.00
IUUC-Atr-002468	Amborella trichopoda	50.26	3.00e-53	201.00
IUUC-Apl-003841	Anas platyrhynchos	99.07	0.00e+00	676.00
IUUC-Aca-005123	Anolis carolinensis	95.06	0.00e+00	649.00
IUUC-Aly-005473	Arabidopsis lyrata	44.65	7.00e-84	303.00
IUUC-Ath-007094	Arabidopsis thaliana	46.18	1.00e-85	309.00
IUUC-Ago-008000	Ashbya gossypii	44.24	2.00e-81	295.00
IUUC-Acl-008098	Aspergillus clavatus	53.47	6.00e-103	366.00
IUUC-Afl-008494	Aspergillus flavus	53.07	1.00e-102	365.00
IUUC-Afu-009080	Aspergillus fumigatus	53.78	4.00e-103	367.00
IUUC-Ani-009230	Aspergillus nidulans	53.52	5.00e-103	367.00
IUUC-Aor-010114	Aspergillus oryzae	53.07	1.00e-102	365.00
IUUC-Ate-010285	Aspergillus terreus	54.74	3.00e-105	374.00
IUUC-Ame-011534	Astyanax mexicanus	83.44	8.00e-171	592.00
IUUC-Bgr-012121	Blumeria graminis	48.48	2.00e-89	321.00
IUUC-Bta-013143	Bos taurus	92.59	0.00e+00	639.00
IUUC-Bci-013950	Botrytis cinerea	51.23	8.00e-98	349.00
IUUC-Bdi-015019	Brachypodium distachyon	46.77	2.00e-87	315.00
IUUC-Bol-015709	Brassica oleracea	46.20	1.00e-82	300.00
IUUC-Bra-017760	Brassica rapa	46.20	6.00e-83	301.00
IUUC-Cel-018226	Caenorhabditis elegans	43.25	2.00e-81	295.00
IUUC-Cja-019741	Callithrix jacchus	93.21	0.00e+00	642.00
IUUC-Cfa-021204	Canis familiaris	92.90	0.00e+00	640.00
IUUC-Cpo-021661	Cavia porcellus	93.21	0.00e+00	641.00
IUUC-Cre-022952	Chlamydomonas reinhardtii	43.48	2.00e-81	295.00
IUUC-Csa-024038	Chlorocebus sabaeus	93.21	0.00e+00	642.00
IUUC-Cin-025597	Ciona intestinalis	60.49	2.00e-119	421.00
IUUC-Cgl-026583	Colletotrichum gloeosporioides	50.76	2.00e-94	338.00
IUUC-Cne-026838	Cryptococcus neoformans	48.16	2.00e-93	335.00
IUUC-Cme-027304	Cyanidioschyzon merolae	45.17	2.00e-81	295.00
IUUC-Dre-028567	Danio rerio	85.19	1.00e-174	604.00
IUUC-Dno-029171	Dasypus novemcinctus	92.90	0.00e+00	640.00
IUUC-Dor-030257	Dipodomys ordii	82.29	3.00e-82	297.00
IUUC-Dse-031191	Dothistroma septosporum	50.15	4.00e-94	337.00
IUUC-Dme-031879	Drosophila melanogaster	60.62	5.00e-121	426.00
IUUC-Ete-032336	Echinops telfairi	90.19	3.00e-116	410.00
IUUC-Eca-033259	Equus caballus	93.21	0.00e+00	641.00
IUUC-Eeu-035153	Erinaceus europaeus	69.80	2.00e-54	205.00
IUUC-Fca-036489	Felis catus	93.21	0.00e+00	641.00
IUUC-Fal-037485	Ficedula albicollis	99.69	0.00e+00	679.00
IUUC-Fox-037860	Fusarium oxysporum	49.39	7.00e-94	336.00
IUUC-Fso-038188	Fusarium solani	50.31	3.00e-93	334.00
IUUC-Gmo-039311	Gadus morhua	85.19	2.00e-174	604.00
IUUC-Ggr-040045	Gaeumannomyces graminis	51.07	2.00e-98	352.00
IUUC-Gga-040645	Gallus gallus	96.69	0.00e+00	669.00
IUUC-Gac-042086	Gasterosteus aculeatus	84.57	4.00e-171	593.00
IUUC-Gma-043246	Glycine max	45.85	3.00e-86	311.00
IUUC-Ggo-045578	Gorilla gorilla	93.21	0.00e+00	642.00
IUUC-Hsa-046734	Homo sapiens	93.21	0.00e+00	642.00
IUUC-Hvu-047553	Hordeum vulgare	46.15	1.00e-86	312.00
IUUC-Itr-048467	Ictidomys tridecemlineatus	92.90	0.00e+00	640.00
IUUC-Kpa-049325	Komagataella pastoris	45.09	4.00e-86	310.00
IUUC-Lch-049620	Latimeria chalumnae	87.54	2.00e-162	564.00
IUUC-Lpe-051338	Leersia perrieri	45.48	7.00e-80	290.00
IUUC-Loc-052094	Lepisosteus oculatus	81.73	3.00e-162	563.00
IUUC-Lma-053047	Leptosphaeria maculans	49.39	2.00e-95	341.00
IUUC-Laf-053801	Loxodonta africana	92.77	0.00e+00	628.00
IUUC-Mcc-055498	Macaca mulatta	83.02	6.00e-155	539.00
IUUC-Meu-056729	Macropus eugenii	86.15	3.00e-168	583.00
IUUC-Mor-057025	Magnaporthe oryzae	51.53	4.00e-96	344.00
IUUC-Mpo-057511	Magnaporthe poae	52.15	1.00e-98	352.00
IUUC-Mtr-058051	Medicago truncatula	46.93	3.00e-86	311.00
IUUC-Mla-059061	Melampsora laricipopulina	47.81	1.00e-85	309.00
IUUC-Mga-059229	Meleagris gallopavo	98.16	0.00e+00	668.00
IUUC-Mvi-060399	Microbotryum violaceum	47.73	1.00e-83	302.00
IUUC-Mmr-060764	Microcebus murinus	93.21	0.00e+00	642.00
IUUC-Mdo-062088	Monodelphis domestica	92.92	0.00e+00	642.00
IUUC-Mmu-064304	Mus musculus	92.59	0.00e+00	639.00
IUUC-Mac-065520	Musa acuminata	47.83	2.00e-88	318.00
IUUC-Mpu-066340	Mustela putorius furo	93.21	0.00e+00	641.00
IUUC-Mlu-067111	Myotis lucifugus	92.90	0.00e+00	641.00
IUUC-Nfi-068478	Neosartorya fischeri	53.17	7.00e-103	366.00
IUUC-Ncr-068820	Neurospora crassa	52.29	1.00e-96	346.00
IUUC-Nle-069903	Nomascus leucogenys	93.21	0.00e+00	643.00
IUUC-Opr-070221	Ochotona princeps	91.05	3.00e-180	623.00
IUUC-Ont-071765	Oreochromis niloticus	87.04	2.00e-176	610.00
IUUC-Oan-073660	Ornithorhynchus anatinus	92.86	6.00e-168	582.00
IUUC-Ocu-074039	Oryctolagus cuniculus	93.21	0.00e+00	642.00
IUUC-Oba-075395	Oryza barthii	39.08	8.00e-69	253.00
IUUC-Obr-076334	Oryza brachyantha	42.77	2.00e-78	285.00
IUUC-Ogl-077060	Oryza glaberrima	46.32	5.00e-84	303.00
IUUC-Ogu-078207	Oryza glumaepatula	46.30	8.00e-87	313.00
IUUC-Oin-079878	Oryza indica	45.85	2.00e-86	311.00
IUUC-Olo-080677	Oryza longistaminata	38.79	2.00e-76	278.00
IUUC-Ome-081228	Oryza meridionalis	33.33	7.00e-35	140.00
IUUC-Oni-082411	Oryza nivara	39.82	5.00e-69	253.00
IUUC-Opu-083136	Oryza punctata	44.92	7.00e-85	306.00
IUUC-Oru-084916	Oryza rufipogon	44.91	3.00e-84	304.00
IUUC-Osa-085454	Oryza sativa	45.85	2.00e-86	311.00
IUUC-Ola-087053	Oryzias latipes	85.80	5.00e-175	606.00
IUUC-Olu-087602	Ostreococcus lucimarinus	47.66	2.00e-87	315.00
IUUC-Oga-088154	Otolemur garnettii	92.90	0.00e+00	639.00
IUUC-Oar-089915	Ovis aries	92.59	0.00e+00	638.00
IUUC-Ptr-091124	Pan troglodytes	75.00	5.00e-139	486.00
IUUC-Pan-092035	Papio anubis	93.21	0.00e+00	642.00
IUUC-Psi-094096	Pelodiscus sinensis	90.78	8.00e-119	418.00
IUUC-Pno-094988	Phaeosphaeria nodorum	45.92	5.00e-83	300.00
IUUC-Ppa-095536	Physcomitrella patens	49.38	9.00e-92	329.00
IUUC-Pfo-096101	Poecilia formosa	85.49	3.00e-174	603.00
IUUC-Pab-097726	Pongo abelii	93.21	0.00e+00	642.00
IUUC-Pop-099617	Populus trichocarpa	47.08	7.00e-88	316.00
IUUC-Pca-101014	Procavia capensis	92.90	0.00e+00	640.00
IUUC-Ppe-101320	Prunus persica	46.77	2.00e-85	308.00
IUUC-Pva-102789	Pteropus vampyrus	81.17	1.00e-155	541.00
IUUC-Pgr-103479	Puccinia graminis	47.19	1.00e-84	306.00
IUUC-Ptt-103981	Puccinia triticina	47.81	1.00e-86	312.00
IUUC-Pte-104278	Pyrenophora teres	49.70	3.00e-93	334.00
IUUC-Pyt-104492	Pyrenophora triticirepentis	49.70	3.00e-93	334.00
IUUC-Rno-105867	Rattus norvegicus	72.62	4.00e-132	463.00
IUUC-Sce-106251	Saccharomyces cerevisiae	45.48	1.00e-84	305.00
IUUC-Sha-107039	Sarcophilus harrisii	92.62	0.00e+00	642.00
IUUC-Sja-107758	Schizosaccharomyces japonicus	51.69	9.00e-97	346.00
IUUC-Spo-108314	Schizosaccharomyces pombe	49.23	2.00e-92	332.00
IUUC-Ssl-108478	Sclerotinia sclerotiorum	50.46	5.00e-97	347.00
IUUC-Smo-108728	Selaginella moellendorffii	47.22	3.00e-85	308.00
IUUC-Sit-110801	Setaria italica	45.54	2.00e-84	305.00
IUUC-Sly-111326	Solanum lycopersicum	47.55	3.00e-87	314.00
IUUC-Stu-112458	Solanum tuberosum	47.55	2.00e-86	311.00
IUUC-Sbi-114063	Sorghum bicolor	44.92	1.00e-83	302.00
IUUC-Sre-115096	Sporisorium reilianum	47.27	1.00e-84	305.00
IUUC-Ssc-116080	Sus scrofa	92.90	0.00e+00	639.00
IUUC-Tru-118766	Takifugu rubripes	85.49	1.00e-174	604.00
IUUC-Tni-120197	Tetraodon nigroviridis	84.88	3.00e-174	603.00
IUUC-Tca-121316	Theobroma cacao	46.46	3.00e-86	311.00
IUUC-Tre-122097	Trichoderma reesei	51.07	7.00e-96	343.00
IUUC-Tvi-122442	Trichoderma virens	51.07	4.00e-96	344.00
IUUC-Tae-125800	Triticum aestivum	46.15	1.00e-86	312.00
IUUC-Tur-126334	Triticum urartu	40.00	3.00e-68	251.00
IUUC-Tme-127038	Tuber melanosporum	53.52	2.00e-102	365.00
IUUC-Ttr-128659	Tursiops truncatus	87.96	3.00e-161	560.00
IUUC-Uma-129464	Ustilago maydis	47.58	4.00e-84	304.00
IUUC-Vda-129841	Verticillium dahliae	52.76	4.00e-97	347.00
IUUC-Vvi-131076	Vitis vinifera	46.93	1.00e-86	312.00
IUUC-Xtr-132395	Xenopus tropicalis	90.12	0.00e+00	629.00
IUUC-Xma-133383	Xiphophorus maculatus	85.19	2.00e-173	600.00
IUUC-Yli-134586	Yarrowia lipolytica	50.15	2.00e-83	302.00
IUUC-Zma-135904	Zea mays	45.85	2.00e-84	305.00

Created Date

25-Jun-2017

Functional Description

Protein Fasta Sequence

Nucleotide Fasta Sequence