iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSGALG00000015889.5	ENSGALT00000025610.5	ENSGALP00000025563.5
ENSGALG00000015889.5	ENSGALT00000072453.1	ENSGALP00000044824.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	1.40e-33	113.8	183	220
UBD/Beta-Prp	8.00e-52	176.6	282	543

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 1    gHtdsvtclaf.sd.tllvsGsdDgtikvWDlrtgvll 36
           gH +sv+c+ f  + +++ +GsdD+ +k+W +++g+ll
   Q: 183  GHLSSVYCVTFdRTgRRIFTGSDDCLVKIWATDDGRLL 220
           8**********955599*****************9987 PP

UBD/Beta-Prp

   S: 19   spdksllatgsrdgtikvwdvttgkl......lrslsgheaevtavk..fspdgkilvtgseDrtikvw..dlstgkcvhtlkghedsv 97
           s +k++l ++++dgti  w ++ g+l       +  +   ++v+ ++  fs  g +l+tgs+D++i+v+     +++ ++ l+ h+d+v
   Q: 282  SGSKRYLSSTGADGTICFWLWDAGTLkinprpTKFTERPRPGVQMICssFSAGGMFLATGSTDHIIRVYffGSGQPEKISELEFHTDKV 370
           67899***********999999999988888544447777777755522778888**************777779999*********** PP
   S: 98   lslsfspsgdklvsGshdrtirvwdletgqclee................tlsghdgvvncvvvhpdgnllvsGslDrtvrlWdlktgk 170
            s++fs s++++vsGs+d t+r+w+ + +++ +                  +++++  v++v+++  +n ++++ ++ t+++W++ tg+
   Q: 371  DSIQFSNSSSRFVSGSRDGTARIWQFKRREWKSIlldmatrpsgqtlqgvEDKITKLKVTMVAWDRHDNSVITAVNNMTLKVWNSFTGQ 459
           ********************************99***********99998788888899****************************** PP
   S: 171  llrtltgghtdsvysls...fdsngkelvsgsldgtvklwdlqtgecvrtlnght.....dnvksvrfspnderlvsgssDgsiriW 249
           l++ l g h+d v  l+   fd+  + l s+++dg v++wdl +g  +r++ +         v + + sp++++++++ s+g + i+
   Q: 460  LIHILMG-HEDEVFVLEphpFDP--RVLFSAGHDGNVIVWDLARGVKIRSYFNMIegqghGAVFDCKCSPDGQHFACTDSHGHLLIF 543
           ******9.*********999999..89******************999998875544444566667777999999999999888887 PP

Organism

Gallus gallus

Protein Sequence
(Fasta)

MSGDGGSRHT AELRAELYFL IARFLEDGPC QQAAQVLIRE VAEKELLPKR TDWTGKEHPR 60
SYQNLVKYYR HLAPDHLLQI CHRLGPLLEQ EIPQSVPGVQ TLLGAGRQSL LRTNKSCKHV 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGTCCGGGG ACGGCGGCAG CAGGCACACG GCGGAGCTGC GAGCGGGTGA GTGCCGGGCG 60
GGAGGGGGAA GAAAGGGCGG GCGGGCGGGC GGCGGGGCCG GGAGCCGCAG CCCTCACCCT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0103--Bromodomain
KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0853--WD repeat

Interpro

IPR001487--Bromodomain
IPR018359--Bromodomain_CS
IPR028738--PHIP
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS00633--BROMODOMAIN_1
PS50014--BROMODOMAIN_2
PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF00439--Bromodomain
PF00400--WD40

PRINTS

PR00503--BROMODOMAIN

SMART

SM00297--BROMO
SM00320--WD40

Gene Ontology

GO:0070062--C:extracellular exosome
GO:0005634--C:nucleus
GO:0007010--P:cytoskeleton organization
GO:0008286--P:insulin receptor signaling pathway
GO:2001237--P:negative regulation of extrinsic apoptotic signaling pathway
GO:0045944--P:positive regulation of transcription from RNA polymerase II promoter
GO:0008360--P:regulation of cell shape
GO:0006357--P:regulation of transcription from RNA polymerase II promoter

KEGG

gga:421854

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002299	Ailuropoda melanoleuca	86.10	0.00e+00	2890.00
IUUC-Atr-002600	Amborella trichopoda	31.36	1.00e-70	262.00
IUUC-Apl-003700	Anas platyrhynchos	96.50	0.00e+00	3209.00
IUUC-Aca-004474	Anolis carolinensis	85.10	0.00e+00	2985.00
IUUC-Bta-013125	Bos taurus	86.01	0.00e+00	2826.00
IUUC-Bol-016525	Brassica oleracea	30.79	1.00e-72	268.00
IUUC-Bra-017961	Brassica rapa	31.68	7.00e-71	263.00
IUUC-Cja-018868	Callithrix jacchus	84.47	0.00e+00	2966.00
IUUC-Cfa-021179	Canis familiaris	84.69	0.00e+00	2847.00
IUUC-Cpo-022077	Cavia porcellus	81.54	0.00e+00	2782.00
IUUC-Csa-023618	Chlorocebus sabaeus	86.16	0.00e+00	2998.00
IUUC-Cho-024794	Choloepus hoffmanni	85.87	0.00e+00	840.00
IUUC-Dno-030048	Dasypus novemcinctus	85.25	0.00e+00	2899.00
IUUC-Dor-030195	Dipodomys ordii	85.49	0.00e+00	1400.00
IUUC-Eca-034274	Equus caballus	86.24	0.00e+00	2857.00
IUUC-Eeu-034688	Erinaceus europaeus	91.48	0.00e+00	1276.00
IUUC-Fca-035451	Felis catus	85.25	0.00e+00	2746.00
IUUC-Fal-037465	Ficedula albicollis	95.29	0.00e+00	3219.00
IUUC-Gmo-039451	Gadus morhua	68.25	0.00e+00	715.00
IUUC-Gma-043340	Glycine max	31.84	3.00e-71	264.00
IUUC-Ggo-045347	Gorilla gorilla	85.19	0.00e+00	2920.00
IUUC-Hsa-046757	Homo sapiens	86.32	0.00e+00	2975.00
IUUC-Hvu-047706	Hordeum vulgare	31.56	4.00e-37	148.00
IUUC-Itr-048843	Ictidomys tridecemlineatus	75.84	0.00e+00	951.00
IUUC-Loc-052672	Lepisosteus oculatus	71.39	0.00e+00	2460.00
IUUC-Laf-054140	Loxodonta africana	85.80	0.00e+00	2903.00
IUUC-Mcc-055061	Macaca mulatta	85.94	0.00e+00	2982.00
IUUC-Mmr-060837	Microcebus murinus	86.11	0.00e+00	2924.00
IUUC-Mdo-061903	Monodelphis domestica	87.51	0.00e+00	3054.00
IUUC-Mmu-063772	Mus musculus	85.78	0.00e+00	2973.00
IUUC-Mpu-066359	Mustela putorius furo	85.41	0.00e+00	2635.00
IUUC-Mlu-067928	Myotis lucifugus	85.62	0.00e+00	2890.00
IUUC-Nle-070094	Nomascus leucogenys	86.42	0.00e+00	2934.00
IUUC-Opr-070971	Ochotona princeps	69.16	0.00e+00	895.00
IUUC-Ont-072221	Oreochromis niloticus	75.03	0.00e+00	1320.00
IUUC-Oan-073185	Ornithorhynchus anatinus	84.68	0.00e+00	2848.00
IUUC-Ocu-074033	Oryctolagus cuniculus	85.85	0.00e+00	2629.00
IUUC-Obr-076619	Oryza brachyantha	30.96	9.00e-71	262.00
IUUC-Ogl-077493	Oryza glaberrima	25.07	1.00e-34	142.00
IUUC-Oin-079669	Oryza indica	31.22	3.00e-52	199.00
IUUC-Olo-080755	Oryza longistaminata	31.86	2.00e-54	208.00
IUUC-Oni-082991	Oryza nivara	27.78	3.00e-39	157.00
IUUC-Oga-088578	Otolemur garnettii	85.68	0.00e+00	2843.00
IUUC-Oar-090247	Ovis aries	86.17	0.00e+00	2826.00
IUUC-Ptr-091266	Pan troglodytes	86.00	0.00e+00	2889.00
IUUC-Pan-092734	Papio anubis	86.27	0.00e+00	3002.00
IUUC-Pfo-096191	Poecilia formosa	72.77	0.00e+00	2084.00
IUUC-Pab-098402	Pongo abelii	86.49	0.00e+00	2984.00
IUUC-Pop-099185	Populus trichocarpa	35.42	1.00e-70	262.00
IUUC-Pca-101128	Procavia capensis	78.50	0.00e+00	2581.00
IUUC-Ppe-101849	Prunus persica	31.85	3.00e-75	277.00
IUUC-Rno-106013	Rattus norvegicus	84.27	0.00e+00	2841.00
IUUC-Sha-107496	Sarcophilus harrisii	87.72	0.00e+00	3002.00
IUUC-Sly-111348	Solanum lycopersicum	31.36	1.00e-74	275.00
IUUC-Sar-113520	Sorex araneus	78.50	0.00e+00	1280.00
IUUC-Ssc-115461	Sus scrofa	82.71	0.00e+00	2807.00
IUUC-Tgu-116821	Taeniopygia guttata	94.96	0.00e+00	3240.00
IUUC-Tsy-119132	Tarsius syrichta	74.77	0.00e+00	2308.00
IUUC-Tae-125478	Triticum aestivum	31.71	6.00e-72	266.00
IUUC-Tur-126809	Triticum urartu	31.74	7.00e-70	259.00
IUUC-Tbe-127479	Tupaia belangeri	80.18	0.00e+00	1260.00
IUUC-Vpa-130160	Vicugna pacos	83.07	0.00e+00	2738.00
IUUC-Vvi-131332	Vitis vinifera	31.53	2.00e-77	284.00
IUUC-Xtr-132717	Xenopus tropicalis	75.50	0.00e+00	2605.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence