iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Bol-016190

Ensembl Protein ID

Bo3g010340.1

UniProt Accession

A0A0D3B1A1; A0A0D3B1A1_BRAOL

Protein Name

Ribosome biogenesis protein WDR12 homolog

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
Bo3g010340	Bo3g010340.1	Bo3g010340.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	5.40e-30	103.6	352	386
UBD/Beta-Prp	1.70e-41	143.8	115	299

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 2    Htdsvtclaf..sd.tllvsGsdDgtikvWDlrtg 33
           H+++++++++  s+  +l+s+s+Dg+i++WDlrt 
   Q: 352  HSSWISACKWhtSSwFHLLSASYDGKIMLWDLRTA 386
           ***********866677***************986 PP

UBD/Beta-Prp

   S: 20   pdksllatgsrdgtikvwdvttgkllrslsgheaevtavkfspdgk....ilvtgseDrtikvwdls.........tgkcvhtlkghedsvlslsfs 103
            + ++++tg++dg  ++w+  +g++ + l+gh+++++++ f +++     + +t+s+Drt++++ ++               +l gh++sv s++ +
   Q: 115  SFPRFVLTGCYDGLGRIWSS-PGSCTHILEGHTGAISSIAFANSEGaegvTVATASRDRTLRLFKVDpaesgdsttRVGAYKILCGHKASVASVAAQ 210
           456899************85.66999*****************9989999**************666557665433333344445************ PP
   S: 104  psgdklvsGshdrtirvwdletgqclee.......................tlsghdgvvncvvvhpdgnllvsGslDrtvrlWdlktgk 170
           ++g+k+ sGs+d ti+vwd+++ +   +                       tl gh++ v++vv+++  +++ s+s D  vr Wd++tgk
   Q: 211  KYGSKVCSGSWDCTINVWDTNESTSELSvpgkkrkgnnqaeepqlegevetTLVGHTQCVSSVVWPE-HDVIYSCSWDHSVRRWDVETGK 299
           ********************999999999************************************99.8999****************98 PP

Organism

Brassica oleracea

Functional Description
(View)

Required for maturation of ribosomal RNAs and formation of the large ribosomal subunit.

Protein Sequence
(Fasta)

MNGEGEDASK VIHVKFLTKL DYPFKVPVTS VVIPSSVTRL GLSSIVNSLL TLEKPEPFDF 60
LIDGELIRMS LEQFLNAKGI SAERTLEIEY IRAVAPRKEE KPSLHDDWVS AVDGSFPRFV 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGAATGGCG AAGGAGAAGA TGCATCCAAA GTAATTCACG TGAAGTTCTT GACGAAGCTT 60
GACTATCCGT TCAAAGTTCC GGTCACCTCC GTCGTTATCC CTTCCAGTGT CACTCGTCTA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0539--Nucleus
KW-1185--Reference proteome
KW-0677--Repeat
KW-0690--Ribosome biogenesis
KW-0698--rRNA processing
KW-0853--WD repeat

Interpro

IPR020472--G-protein_beta_WD-40_rep
IPR012972--NLE
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom
IPR028599--WDR12/Ytm1

PROSITE

PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF08154--NLE
PF00400--WD40

PRINTS

PR00320--GPROTEINBRPT

SMART

SM00320--WD40

Gene Ontology

GO:0005730--C:nucleolus
GO:0005654--C:nucleoplasm
GO:0030687--C:preribosome, large subunit precursor
GO:0043021--F:ribonucleoprotein complex binding
GO:0000466--P:maturation of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
GO:0000463--P:maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aca-004370	Anolis carolinensis	34.23	2.00e-60	226.00
IUUC-Ago-007864	Ashbya gossypii	33.04	1.00e-51	197.00
IUUC-Afl-008617	Aspergillus flavus	30.22	8.00e-40	157.00
IUUC-Afu-008752	Aspergillus fumigatus	30.41	1.00e-41	164.00
IUUC-Ang-009701	Aspergillus niger	31.03	4.00e-40	158.00
IUUC-Aor-009884	Aspergillus oryzae	30.22	2.00e-40	159.00
IUUC-Ame-011432	Astyanax mexicanus	33.73	5.00e-63	234.00
IUUC-Bgr-012218	Blumeria graminis	29.74	2.00e-40	159.00
IUUC-Bta-012829	Bos taurus	33.00	4.00e-54	205.00
IUUC-Bci-013953	Botrytis cinerea	28.01	1.00e-39	157.00
IUUC-Bra-018095	Brassica rapa	96.03	0.00e+00	807.00
IUUC-Cja-019468	Callithrix jacchus	34.24	3.00e-52	199.00
IUUC-Cfa-020471	Canis familiaris	33.41	3.00e-51	195.00
IUUC-Cho-024426	Choloepus hoffmanni	32.59	7.00e-42	164.00
IUUC-Cne-027063	Cryptococcus neoformans	27.54	5.00e-29	122.00
IUUC-Dno-029225	Dasypus novemcinctus	33.50	8.00e-54	204.00
IUUC-Dor-031082	Dipodomys ordii	31.80	4.00e-24	105.00
IUUC-Dme-032189	Drosophila melanogaster	30.32	2.00e-47	182.00
IUUC-Ete-032247	Echinops telfairi	31.95	8.00e-47	180.00
IUUC-Eeu-035322	Erinaceus europaeus	30.69	4.00e-45	175.00
IUUC-Fca-036114	Felis catus	33.50	9.00e-54	203.00
IUUC-Fox-037965	Fusarium oxysporum	25.84	3.00e-33	135.00
IUUC-Fso-038244	Fusarium solani	25.31	2.00e-33	136.00
IUUC-Gmo-039040	Gadus morhua	35.71	2.00e-65	243.00
IUUC-Gac-042117	Gasterosteus aculeatus	34.06	1.00e-62	233.00
IUUC-Itr-048275	Ictidomys tridecemlineatus	33.74	9.00e-55	207.00
IUUC-Kpa-049304	Komagataella pastoris	28.91	5.00e-46	178.00
IUUC-Lch-050655	Latimeria chalumnae	34.12	2.00e-43	169.00
IUUC-Loc-052868	Lepisosteus oculatus	34.46	5.00e-61	228.00
IUUC-Laf-053993	Loxodonta africana	33.90	8.00e-54	204.00
IUUC-Mcc-055128	Macaca mulatta	28.75	4.00e-34	138.00
IUUC-Mpo-057463	Magnaporthe poae	33.95	8.00e-19	86.70
IUUC-Mpu-066284	Mustela putorius furo	33.74	5.00e-54	205.00
IUUC-Nfi-068260	Neosartorya fischeri	30.62	5.00e-43	168.00
IUUC-Ncr-068719	Neurospora crassa	28.22	4.00e-35	142.00
IUUC-Nle-068981	Nomascus leucogenys	34.63	8.00e-52	197.00
IUUC-Opr-071218	Ochotona princeps	32.99	6.00e-50	191.00
IUUC-Ont-071646	Oreochromis niloticus	33.17	3.00e-58	218.00
IUUC-Ola-087420	Oryzias latipes	33.41	1.00e-60	226.00
IUUC-Olu-087740	Ostreococcus lucimarinus	35.25	1.00e-63	236.00
IUUC-Oga-088264	Otolemur garnettii	33.00	3.00e-52	198.00
IUUC-Pca-100394	Procavia capensis	32.20	4.00e-45	175.00
IUUC-Ptt-103781	Puccinia triticina	25.51	5.00e-35	142.00
IUUC-Rno-105114	Rattus norvegicus	34.73	3.00e-56	212.00
IUUC-Sce-106401	Saccharomyces cerevisiae	30.43	8.00e-50	191.00
IUUC-Sja-107766	Schizosaccharomyces japonicus	27.90	1.00e-38	153.00
IUUC-Spo-108134	Schizosaccharomyces pombe	29.10	2.00e-37	150.00
IUUC-Sre-115002	Sporisorium reilianum	30.61	8.00e-21	94.70
IUUC-Tni-119820	Tetraodon nigroviridis	34.20	6.00e-59	221.00
IUUC-Tme-126900	Tuber melanosporum	31.05	5.00e-51	194.00
IUUC-Uma-129628	Ustilago maydis	29.63	3.00e-12	66.60
IUUC-Vpa-130260	Vicugna pacos	33.50	2.00e-54	206.00
IUUC-Xtr-132083	Xenopus tropicalis	34.35	1.00e-56	213.00

Created Date

25-Jun-2017

Functional Description

Protein Fasta Sequence

Nucleotide Fasta Sequence