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Tag Content
UUCD2 ID IUUC-Gga-040610
UUCD1 version UUC-GaG-00686
Ensembl Protein ID ENSGALP00000060881.1
UniProt Accession A0A1L1RQ17; A0A1L1RQ17_CHICK
Genbank Protein ID ENSGALP00000060881
Protein Name Ribosome biogenesis protein WDR12; WD repeat-containing protein 12
Genbank Nucleotide ID AADN04000048
Gene Name WDR12
Ensembl Information
Ensembl Gene ID Ensembl Transcript ID Ensembl Protein ID
ENSGALG00000008470.6 ENSGALT00000013803.5 ENSGALP00000013788.5
ENSGALG00000008470.6 ENSGALT00000083978.1 ENSGALP00000060881.1
Status Unreviewed
Classification
Family E-Value Score Start End
E3 adaptor/Cullin RING/DCX/DWD 5.30e-43 143.5 341 376
UBD/Beta-Prp 2.50e-45 155.3 246 412
Active Site
Position(s) Description Evidence
N/A N/A N/A
Domain Profile

   E3 adaptor/Cullin RING/DCX/DWD
   S: 2    Htdsvtclaf.sd..tllvsGsdDgtikvWDlrtgv 34
           Ht++vt++++ ++  + l+sGs D+ +k+WD+r+++
   Q: 341  HTGWVTSVKWsPTheHQLISGSLDNIVKLWDTRSCK 376
           **********9444577**************99876 PP
   

   UBD/Beta-Prp
   S: 83   tgkcvhtlkghedsvlslsfspsgdklvsGshdrtirvwdletgqcleetlsghdgvvncvvvhpdgnllvsGslDrtvrlWdlktgkl 171
           t++++ tl+gh++ + s+ +s   + + s+s+d ti++wd etg   + tl+g++ v n+v+++p ++ l+sGs+Dr +rlWd ++++ 
   Q: 246  TRTPLATLSGHTEAISSVLWSD-AEEICSASWDHTIKLWDAETGGLKS-TLTGNK-VFNSVSYSPLCRRLASGSTDRHIRLWDPRSKDG 331
           677899***************9.99**********************9.***987.99**************************66654 PP
   S: 172  lrtl...tgghtdsvyslsfdsng.kelvsgsldgtvklwdlq.tgecvrtlnghtdnvksvrfspnderlvsgssDgsiriW 249
              l   t+ ht+ v+s++++++   +l+sgsld+ vklwd +  +  ++ l +h+d v++v+ + +  +l+sg++D+ ++++
   Q: 332  SLVLlslTS-HTGWVTSVKWSPTHeHQLISGSLDNIVKLWDTRsCKAPLYDLAAHEDKVLCVDWT-EAGLLLSGGADNKLYCY 412
           333334387.************99788****************54566****************9.999**********9997 PP
   
Organism Gallus gallus
Functional Description
(View)

Functional Description


     Component of the PeBoW complex, which is required for maturation of 28S and 5.8S ribosomal RNAs and formation of the 60S ribosome.
 Component of the PeBoW complex, which is required for maturation of 28S and 5.8S ribosomal RNAs and formation of the 60S ribosome.
Protein Sequence
(Fasta)
MAQLTARFRT ENPRYAVEDV PFSVPAASET ADLSHLINKL LAARGADHKY VEFDFLIQGQ 60
FLRVPLVTHM EMENISTEEV VEIEYVEKYM APQPEECIFH DDWISSVQAT EEWILTGCYD 120
It may take some time, please wait.

Protein Fasta Sequence


>IUUC-Gga-040610|E3,WD_repeat;UBD,Beta-Prp|Gallus gallus
Please wait for a moment...
Nucleotide Sequence
(Fasta)
GGCCGCGGGA GGGGCTCCGT GACGGCGCGC GGGCTGCTGG GGGCCGCGGT GCCGACGGCA 60
GCATGGCGCA GCTCACAGCG AGGTTCCGCA CCGAGAACCC CAGGTGAGGC GCGGCCGGGC 120
It may take some time, please wait.

Nucleotide Fasta Sequence


>IUUC-Gga-040610|E3,WD_repeat;UBD,Beta-Prp|Gallus gallus
Please wait for a moment...
Sequence Source Ensembl
Keyword

KW-0181--Complete proteome
KW-0539--Nucleus
KW-1185--Reference proteome
KW-0677--Repeat
KW-0690--Ribosome biogenesis
KW-0698--rRNA processing
KW-0853--WD repeat
Interpro

IPR020472--G-protein_beta_WD-40_rep
IPR012972--NLE
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom
IPR028599--WDR12/Ytm1
PROSITE

PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION
Pfam

PF08154--NLE
PF00400--WD40
PRINTS

PR00320--GPROTEINBRPT
SMART

SM00320--WD40
Gene Ontology

GO:0005730--C:nucleolus
GO:0005654--C:nucleoplasm
GO:0030687--C:preribosome, large subunit precursor
GO:0043021--F:ribonucleoprotein complex binding
GO:0000466--P:maturation of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
GO:0000463--P:maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
Orthology
iUUCD ID Species Identity E-value Score
IUUC-Ata-000532 Aegilops tauschii 33.49 4.00e-60 224.00
IUUC-Aml-001997 Ailuropoda melanoleuca 85.37 0.00e+00 670.00
IUUC-Atr-002544 Amborella trichopoda 32.86 1.00e-54 206.00
IUUC-Apl-003981 Anas platyrhynchos 97.88 0.00e+00 721.00
IUUC-Aca-004370 Anolis carolinensis 84.00 0.00e+00 720.00
IUUC-Aly-006455 Arabidopsis lyrata 33.99 3.00e-56 212.00
IUUC-Ath-006669 Arabidopsis thaliana 34.79 2.00e-52 199.00
IUUC-Ago-007864 Ashbya gossypii 29.55 1.00e-38 154.00
IUUC-Acl-008177 Aspergillus clavatus 29.85 2.00e-36 146.00
IUUC-Afl-008617 Aspergillus flavus 30.95 1.00e-36 147.00
IUUC-Afu-008752 Aspergillus fumigatus 29.49 2.00e-34 139.00
IUUC-Ani-009136 Aspergillus nidulans 29.82 2.00e-36 146.00
IUUC-Ang-009701 Aspergillus niger 29.67 5.00e-35 142.00
IUUC-Aor-009884 Aspergillus oryzae 30.18 7.00e-36 144.00
IUUC-Ame-011432 Astyanax mexicanus 77.78 0.00e+00 673.00
IUUC-Bgr-012218 Blumeria graminis 28.37 2.00e-33 136.00
IUUC-Bta-012829 Bos taurus 84.40 0.00e+00 688.00
IUUC-Bci-013953 Botrytis cinerea 29.40 4.00e-35 142.00
IUUC-Bdi-014351 Brachypodium distachyon 35.07 1.00e-55 210.00
IUUC-Bol-016514 Brassica oleracea 34.98 2.00e-52 199.00
IUUC-Bra-017876 Brassica rapa 34.64 8.00e-55 207.00
IUUC-Cel-018569 Caenorhabditis elegans 32.93 3.00e-49 189.00
IUUC-Cja-019468 Callithrix jacchus 83.22 0.00e+00 662.00
IUUC-Cfa-020471 Canis familiaris 83.45 0.00e+00 676.00
IUUC-Cpo-022260 Cavia porcellus 83.69 0.00e+00 670.00
IUUC-Cre-022614 Chlamydomonas reinhardtii 30.20 1.00e-37 150.00
IUUC-Csa-023989 Chlorocebus sabaeus 83.69 0.00e+00 669.00
IUUC-Cho-024426 Choloepus hoffmanni 84.76 5.00e-147 513.00
IUUC-Cin-025789 Ciona intestinalis 43.53 8.00e-96 343.00
IUUC-Cne-027063 Cryptococcus neoformans 24.90 5.00e-20 92.00
IUUC-Dre-027907 Danio rerio 78.49 0.00e+00 679.00
IUUC-Dno-029225 Dasypus novemcinctus 84.16 0.00e+00 684.00
IUUC-Dor-031082 Dipodomys ordii 69.03 3.00e-148 517.00
IUUC-Dse-031308 Dothistroma septosporum 28.83 6.00e-37 148.00
IUUC-Dme-032189 Drosophila melanogaster 41.75 6.00e-94 337.00
IUUC-Ete-032247 Echinops telfairi 78.01 0.00e+00 628.00
IUUC-Eca-034285 Equus caballus 83.69 0.00e+00 682.00
IUUC-Eeu-035322 Erinaceus europaeus 76.13 3.00e-169 587.00
IUUC-Fca-036114 Felis catus 83.69 0.00e+00 681.00
IUUC-Fal-036891 Ficedula albicollis 98.59 0.00e+00 673.00
IUUC-Fox-037965 Fusarium oxysporum 25.90 5.00e-32 132.00
IUUC-Fso-038244 Fusarium solani 25.90 3.00e-32 132.00
IUUC-Gmo-039040 Gadus morhua 76.12 0.00e+00 659.00
IUUC-Gac-042117 Gasterosteus aculeatus 76.12 0.00e+00 632.00
IUUC-Gma-043146 Glycine max 35.49 1.00e-61 229.00
IUUC-Ggo-045179 Gorilla gorilla 83.22 0.00e+00 658.00
IUUC-Hsa-046114 Homo sapiens 83.92 0.00e+00 663.00
IUUC-Hvu-047331 Hordeum vulgare 33.85 3.00e-55 208.00
IUUC-Itr-048275 Ictidomys tridecemlineatus 83.92 0.00e+00 686.00
IUUC-Kpa-049304 Komagataella pastoris 30.67 4.00e-45 175.00
IUUC-Lch-050655 Latimeria chalumnae 74.34 2.00e-144 504.00
IUUC-Lpe-051675 Leersia perrieri 35.32 6.00e-60 224.00
IUUC-Loc-052868 Lepisosteus oculatus 80.38 0.00e+00 680.00
IUUC-Lma-053258 Leptosphaeria maculans 28.11 2.00e-34 141.00
IUUC-Laf-053993 Loxodonta africana 83.92 0.00e+00 683.00
IUUC-Mcc-055128 Macaca mulatta 68.09 2.00e-148 518.00
IUUC-Meu-056501 Macropus eugenii 74.26 2.00e-152 531.00
IUUC-Mor-057114 Magnaporthe oryzae 25.77 1.00e-25 110.00
IUUC-Mtr-058367 Medicago truncatula 35.73 6.00e-59 221.00
IUUC-Mla-059107 Melampsora laricipopulina 27.16 2.00e-29 122.00
IUUC-Mga-059745 Meleagris gallopavo 97.13 0.00e+00 785.00
IUUC-Mvi-060362 Microbotryum violaceum 27.86 2.00e-31 130.00
IUUC-Mdo-062257 Monodelphis domestica 80.00 0.00e+00 684.00
IUUC-Mmu-063546 Mus musculus 83.92 0.00e+00 685.00
IUUC-Mac-065540 Musa acuminata 32.78 2.00e-55 209.00
IUUC-Mpu-066284 Mustela putorius furo 83.92 0.00e+00 684.00
IUUC-Mlu-067241 Myotis lucifugus 83.22 0.00e+00 681.00
IUUC-Nfi-068260 Neosartorya fischeri 29.92 2.00e-34 139.00
IUUC-Ncr-068719 Neurospora crassa 27.01 1.00e-26 114.00
IUUC-Nle-068981 Nomascus leucogenys 83.22 0.00e+00 662.00
IUUC-Opr-071218 Ochotona princeps 76.38 2.00e-176 611.00
IUUC-Ont-071646 Oreochromis niloticus 75.95 0.00e+00 653.00
IUUC-Oan-073453 Ornithorhynchus anatinus 85.58 0.00e+00 727.00
IUUC-Ocu-074008 Oryctolagus cuniculus 84.16 0.00e+00 686.00
IUUC-Oba-075712 Oryza barthii 30.12 1.00e-43 170.00
IUUC-Obr-076721 Oryza brachyantha 33.97 2.00e-59 223.00
IUUC-Ogl-077229 Oryza glaberrima 34.21 5.00e-60 224.00
IUUC-Ogu-078977 Oryza glumaepatula 30.12 5.00e-44 171.00
IUUC-Oin-079683 Oryza indica 34.21 2.00e-60 226.00
IUUC-Olo-080291 Oryza longistaminata 29.05 9.00e-29 120.00
IUUC-Ome-081834 Oryza meridionalis 34.69 2.00e-61 229.00
IUUC-Oni-082507 Oryza nivara 32.61 9.00e-55 207.00
IUUC-Opu-083396 Oryza punctata 34.21 9.00e-60 224.00
IUUC-Oru-085220 Oryza rufipogon 32.85 1.00e-54 206.00
IUUC-Osa-085767 Oryza sativa 34.21 2.00e-60 226.00
IUUC-Ola-087420 Oryzias latipes 76.36 0.00e+00 660.00
IUUC-Olu-087740 Ostreococcus lucimarinus 29.04 1.00e-38 153.00
IUUC-Oga-088264 Otolemur garnettii 82.51 0.00e+00 677.00
IUUC-Oar-089335 Ovis aries 83.45 0.00e+00 681.00
IUUC-Ptr-091320 Pan troglodytes 83.92 0.00e+00 663.00
IUUC-Pan-092833 Papio anubis 84.16 0.00e+00 668.00
IUUC-Psi-093504 Pelodiscus sinensis 87.47 0.00e+00 715.00
IUUC-Pma-094189 Petromyzon marinus 67.92 4.00e-168 583.00
IUUC-Pno-094929 Phaeosphaeria nodorum 27.04 5.00e-38 151.00
IUUC-Ppa-095429 Physcomitrella patens 33.49 2.00e-60 226.00
IUUC-Pfo-096337 Poecilia formosa 75.41 0.00e+00 660.00
IUUC-Pab-097571 Pongo abelii 83.69 0.00e+00 662.00
IUUC-Pop-099977 Populus trichocarpa 34.86 6.00e-62 231.00
IUUC-Pca-100394 Procavia capensis 79.46 1.00e-178 618.00
IUUC-Ppe-101848 Prunus persica 36.21 4.00e-61 228.00
IUUC-Pva-102921 Pteropus vampyrus 81.38 7.00e-104 370.00
IUUC-Pgr-103637 Puccinia graminis 28.57 5.00e-35 142.00
IUUC-Ptt-103781 Puccinia triticina 27.87 2.00e-34 140.00
IUUC-Pte-104135 Pyrenophora teres 28.44 1.00e-37 152.00
IUUC-Pyt-104609 Pyrenophora triticirepentis 28.20 1.00e-35 144.00
IUUC-Rno-105114 Rattus norvegicus 82.03 0.00e+00 679.00
IUUC-Sce-106401 Saccharomyces cerevisiae 29.07 1.00e-40 160.00
IUUC-Sha-107122 Sarcophilus harrisii 81.27 0.00e+00 656.00
IUUC-Sja-107766 Schizosaccharomyces japonicus 30.50 1.00e-47 184.00
IUUC-Spo-108134 Schizosaccharomyces pombe 29.75 6.00e-41 161.00
IUUC-Ssl-108398 Sclerotinia sclerotiorum 28.54 2.00e-36 146.00
IUUC-Smo-108720 Selaginella moellendorffii 33.01 1.00e-52 199.00
IUUC-Sit-110311 Setaria italica 35.71 3.00e-59 222.00
IUUC-Sly-111023 Solanum lycopersicum 31.64 7.00e-54 204.00
IUUC-Stu-112778 Solanum tuberosum 34.13 1.00e-58 220.00
IUUC-Sar-113596 Sorex araneus 70.21 1.00e-151 528.00
IUUC-Sbi-114193 Sorghum bicolor 35.22 3.00e-58 219.00
IUUC-Sre-115002 Sporisorium reilianum 27.07 2.00e-12 67.40
IUUC-Ssc-116066 Sus scrofa 83.45 0.00e+00 678.00
IUUC-Tgu-117048 Taeniopygia guttata 97.35 0.00e+00 716.00
IUUC-Tsy-119573 Tarsius syrichta 53.59 2.00e-115 408.00
IUUC-Tni-119820 Tetraodon nigroviridis 74.94 0.00e+00 650.00
IUUC-Tca-121605 Theobroma cacao 34.38 1.00e-59 223.00
IUUC-Tre-121947 Trichoderma reesei 26.28 1.00e-32 134.00
IUUC-Tvi-122481 Trichoderma virens 27.34 5.00e-34 138.00
IUUC-Tae-123847 Triticum aestivum 33.49 4.00e-60 224.00
IUUC-Tur-126586 Triticum urartu 33.85 3.00e-57 215.00
IUUC-Tme-126900 Tuber melanosporum 31.24 3.00e-47 182.00
IUUC-Tbe-127736 Tupaia belangeri 62.56 3.00e-125 441.00
IUUC-Ttr-129041 Tursiops truncatus 72.58 6.00e-170 589.00
IUUC-Uma-129628 Ustilago maydis 26.46 7.00e-10 58.50
IUUC-Vpa-130260 Vicugna pacos 83.45 0.00e+00 682.00
IUUC-Vvi-131009 Vitis vinifera 34.05 7.00e-58 217.00
IUUC-Xtr-132083 Xenopus tropicalis 78.01 0.00e+00 671.00
IUUC-Xma-133094 Xiphophorus maculatus 74.94 0.00e+00 655.00
IUUC-Yli-134531 Yarrowia lipolytica 25.30 2.00e-19 90.10
IUUC-Zma-135509 Zea mays 34.29 4.00e-59 221.00
Created Date 25-Jun-2017

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