iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Itr-048952

Ensembl Protein ID

ENSSTOP00000009829.2

UniProt Accession

I3MGF1; I3MGF1_ICTTR

Genbank Protein ID

ENSSTOP00000009829

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AGTP01080747

Gene Name

PPARA

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSSTOG00000010957.2	ENSSTOT00000010955.2	ENSSTOP00000009829.2

Status

Unreviewed

Classification

Family	Identity	E-Value	Score	Source Orthology
E3 activity/RING/RING	92.95	0.00e+00	870.00	IUUC-Hsa-046893

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Organism

Ictidomys tridecemlineatus

Protein Sequence
(Fasta)

MVDTESPICP LSPLEADGLE SPLSEEFLQE MGNIQDISQS IGEDSSGSFS FTEYQYLGSG 60
PGSDGSAITD TLSPASSPSS VSYPVVPGSV DEPPGGTLNI ECRICGDKAS GYHYGVHACE 120

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Nucleotide Sequence
(Fasta)

TGACCCTCTC CAGTCAACAT GGTGGACACG GAGAGCCCCA TCTGCCCCCT CTCTCCGCTC 60
GAGGCTGATG GCCTGGAAAG CCCGTTATCT GAAGAATTCC TACAAGAGAT GGGAAACATC 120

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Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0238--DNA-binding
KW-0479--Metal-binding
KW-0539--Nucleus
KW-0675--Receptor
KW-1185--Reference proteome
KW-0804--Transcription
KW-0805--Transcription regulation
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR003074--1Cnucl_rcpt
IPR003076--1Cnucl_rcpt_A
IPR000536--Nucl_hrmn_rcpt_lig-bd
IPR001723--Nuclear_hrmn_rcpt
IPR001628--Znf_hrmn_rcpt
IPR013088--Znf_NHR/GATA

PROSITE

PS00031--NUCLEAR_REC_DBD_1
PS51030--NUCLEAR_REC_DBD_2

Pfam

PF00104--Hormone_recep
PF00105--zf-C4

PRINTS

PR01288--PROXISOMEPAR
PR01289--PROXISOMPAAR
PR00398--STRDHORMONER
PR00047--STROIDFINGER

SMART

SM00430--HOLI
SM00399--ZnF_C4

Gene Ontology

GO:0005654--C:nucleoplasm
GO:0008144--F:drug binding
GO:0008289--F:lipid binding
GO:0000978--F:RNA polymerase II core promoter proximal region sequence-specific DNA binding
GO:0004879--F:RNA polymerase II transcription factor activity, ligand-activated sequence-specific DNA binding
GO:0003707--F:steroid hormone receptor activity
GO:0001077--F:transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding
GO:0001190--F:transcriptional activator activity, RNA polymerase II transcription factor binding
GO:0001078--F:transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding
GO:0008270--F:zinc ion binding
GO:0032922--P:circadian regulation of gene expression
GO:0070166--P:enamel mineralization
GO:0008544--P:epidermis development
GO:0006631--P:fatty acid metabolic process
GO:0032099--P:negative regulation of appetite
GO:0010887--P:negative regulation of cholesterol storage
GO:0050728--P:negative regulation of inflammatory response
GO:1903038--P:negative regulation of leukocyte cell-cell adhesion
GO:0010745--P:negative regulation of macrophage derived foam cell differentiation
GO:1902894--P:negative regulation of pri-miRNA transcription from RNA polymerase II promoter
GO:0010871--P:negative regulation of receptor biosynthetic process
GO:0010891--P:negative regulation of sequestering of triglyceride
GO:0046321--P:positive regulation of fatty acid oxidation
GO:0045722--P:positive regulation of gluconeogenesis
GO:0072366--P:regulation of cellular ketone metabolic process by positive regulation of transcription from RNA polymerase II promoter
GO:0042752--P:regulation of circadian rhythm
GO:0072363--P:regulation of glycolytic process by positive regulation of transcription from RNA polymerase II promoter
GO:0072369--P:regulation of lipid transport by positive regulation of transcription from RNA polymerase II promoter
GO:0042060--P:wound healing

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002222	Ailuropoda melanoleuca	91.06	0.00e+00	866.00
IUUC-Apl-003330	Anas platyrhynchos	85.81	0.00e+00	798.00
IUUC-Aca-004598	Anolis carolinensis	83.12	0.00e+00	785.00
IUUC-Acl-008339	Aspergillus clavatus	48.48	5.60e-02	30.40
IUUC-Ame-011508	Astyanax mexicanus	72.13	0.00e+00	670.00
IUUC-Bta-012621	Bos taurus	92.52	0.00e+00	865.00
IUUC-Cja-019688	Callithrix jacchus	92.31	0.00e+00	868.00
IUUC-Cfa-020859	Canis familiaris	91.45	0.00e+00	873.00
IUUC-Cpo-021607	Cavia porcellus	88.03	0.00e+00	825.00
IUUC-Csa-023313	Chlorocebus sabaeus	92.31	0.00e+00	862.00
IUUC-Cho-024741	Choloepus hoffmanni	82.05	0.00e+00	736.00
IUUC-Cgl-026615	Colletotrichum gloeosporioides	32.20	3.20e-01	27.30
IUUC-Dre-027446	Danio rerio	71.49	0.00e+00	656.00
IUUC-Dno-029173	Dasypus novemcinctus	91.24	0.00e+00	824.00
IUUC-Dor-030581	Dipodomys ordii	91.01	0.00e+00	811.00
IUUC-Dse-031528	Dothistroma septosporum	29.23	8.30e-01	28.50
IUUC-Dme-031794	Drosophila melanogaster	36.01	4.00e-56	213.00
IUUC-Ete-032330	Echinops telfairi	88.25	0.00e+00	828.00
IUUC-Eca-033712	Equus caballus	91.67	0.00e+00	851.00
IUUC-Fca-036555	Felis catus	92.34	0.00e+00	872.00
IUUC-Fal-036677	Ficedula albicollis	85.68	0.00e+00	793.00
IUUC-Gmo-039240	Gadus morhua	79.20	1.00e-180	625.00
IUUC-Gga-040473	Gallus gallus	86.54	0.00e+00	803.00
IUUC-Gac-041872	Gasterosteus aculeatus	70.40	0.00e+00	664.00
IUUC-Ggo-045226	Gorilla gorilla	92.95	0.00e+00	868.00
IUUC-Hsa-046893	Homo sapiens	92.95	0.00e+00	868.00
IUUC-Lch-050116	Latimeria chalumnae	78.63	0.00e+00	728.00
IUUC-Loc-052131	Lepisosteus oculatus	82.06	0.00e+00	652.00
IUUC-Laf-054323	Loxodonta africana	91.45	0.00e+00	861.00
IUUC-Mcc-054841	Macaca mulatta	92.95	0.00e+00	867.00
IUUC-Meu-056833	Macropus eugenii	79.91	0.00e+00	726.00
IUUC-Mga-059995	Meleagris gallopavo	77.54	0.00e+00	705.00
IUUC-Mmr-060576	Microcebus murinus	65.44	3.00e-148	518.00
IUUC-Mdo-061954	Monodelphis domestica	86.45	0.00e+00	738.00
IUUC-Mmu-064295	Mus musculus	92.31	0.00e+00	834.00
IUUC-Mpu-066216	Mustela putorius furo	91.67	0.00e+00	872.00
IUUC-Mlu-067978	Myotis lucifugus	65.17	2.00e-151	528.00
IUUC-Nle-069970	Nomascus leucogenys	92.74	0.00e+00	867.00
IUUC-Opr-070630	Ochotona princeps	66.55	1.00e-115	409.00
IUUC-Ont-071594	Oreochromis niloticus	71.46	0.00e+00	655.00
IUUC-Oan-073501	Ornithorhynchus anatinus	89.24	0.00e+00	716.00
IUUC-Ocu-074634	Oryctolagus cuniculus	84.49	0.00e+00	823.00
IUUC-Oni-082926	Oryza nivara	29.41	8.00e-03	31.20
IUUC-Ola-086585	Oryzias latipes	77.39	2.00e-178	617.00
IUUC-Oga-088738	Otolemur garnettii	92.95	0.00e+00	863.00
IUUC-Oar-090453	Ovis aries	91.88	0.00e+00	863.00
IUUC-Ptr-091518	Pan troglodytes	92.74	0.00e+00	862.00
IUUC-Pan-092006	Papio anubis	92.74	0.00e+00	862.00
IUUC-Psi-093352	Pelodiscus sinensis	84.11	0.00e+00	791.00
IUUC-Pfo-096060	Poecilia formosa	70.61	0.00e+00	647.00
IUUC-Pab-098602	Pongo abelii	86.71	0.00e+00	769.00
IUUC-Pca-100861	Procavia capensis	65.44	1.00e-144	506.00
IUUC-Pva-102175	Pteropus vampyrus	86.32	0.00e+00	808.00
IUUC-Rno-105283	Rattus norvegicus	92.95	0.00e+00	838.00
IUUC-Sce-106436	Saccharomyces cerevisiae	29.03	1.90e-02	30.40
IUUC-Sha-106560	Sarcophilus harrisii	89.74	0.00e+00	820.00
IUUC-Smo-109075	Selaginella moellendorffii	30.00	1.00e-01	29.60
IUUC-Sar-112996	Sorex araneus	54.33	2.00e-113	402.00
IUUC-Ssc-115266	Sus scrofa	90.60	0.00e+00	865.00
IUUC-Tgu-116778	Taeniopygia guttata	85.26	0.00e+00	790.00
IUUC-Tru-118436	Takifugu rubripes	69.77	0.00e+00	653.00
IUUC-Tsy-119642	Tarsius syrichta	94.81	4.00e-129	454.00
IUUC-Tni-119859	Tetraodon nigroviridis	69.98	0.00e+00	650.00
IUUC-Tvi-122624	Trichoderma virens	30.91	7.90e-02	29.30
IUUC-Tbe-127464	Tupaia belangeri	90.81	0.00e+00	862.00
IUUC-Ttr-129307	Tursiops truncatus	88.49	0.00e+00	813.00
IUUC-Vpa-130378	Vicugna pacos	64.00	2.00e-115	409.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence