iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Mdo-061929

UUCD1 version

UUC-MoD-01137

Ensembl Protein ID

ENSMODP00000010561.3

UniProt Accession

F7FTT0; F7FTT0_MONDO

Protein Name

Uncharacterized protein

Gene Name

USP47

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSMODG00000008494.3	ENSMODT00000010767.3	ENSMODP00000010561.3
ENSMODG00000008494.3	ENSMODT00000043455.1	ENSMODP00000040349.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
DUB/USP	1.80e-75	254.4	187	561

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

DUB/USP

   S: 1    tGlkNlgNtCYmNSvLQcLsnipelrelllekkkeklneenpkepkgellkslqklfeelwkskkkavsprellkalkkeaeefsgyeq 89
           +Gl N+  tCY+NS+LQ+L+++pe+r++l +    +++e++ ++p +++  +lq+lf  l++skk+a++++++++++++ ++e    +q
   Q: 187  VGLVNQAMTCYLNSLLQTLFMTPEFRNALYK---WEFEESE-EDPVTSIPYQLQRLFVLLQTSKKRAIETTDVTRSFGWDSSE--AWQQ 269
           6******************************...5555443.5899*********************************9998..9*** PP
   S: 90   qDaqEflaflldqleeelkkeknkpkeeeeeedkselsdeaeekkkkknkslisdlFqgqlksqikclecdnvssreepfldlslpvpg 178
           +D+qE++++++d+le++                           k++++ +li++l+qg+lk+ ++clec+ +  r ++ ld++l ++ 
   Q: 270  HDVQELCRVMFDALEQKW--------------------------KQTEQADLINELYQGKLKDYVRCLECGYEGWRIDTYLDIPLVIRP 332
           ******************..........................678999*************************************95 PP
   S: 179  ke.etkkeslqdcLesftkeeelegenkyycekckkkqeaekklklkklPevLilhLkRfsfseeqksrekinkkvefpleLdlspfct 266
              +++  s++++L++f ++e l+g n+y+ce+ckkk++a+k l++ ++P  L+l+LkRf f+ ++++r+k+n++++fp+eLd+s f  
   Q: 333  YGsSQAFASVEEALHAFIQPEILDGPNQYFCERCKKKCDARKGLRFLHFPYLLTLQLKRFDFDYTTMHRIKLNDRMTFPEELDMSTFID 421
           54045678******************************************************************************998 PP
   S: 267  speekqke.....................................................kkkYeLiavvvHsGslssGHYvayvkne 302
            ++ek+ +                                                     +  YeL++v+vHsGs+ +GHY+a++k+ 
   Q: 422  IEDEKSPQtesctdsgaenegschsdqmsndfsnddgvdegiclesssgtekitkpgleknSLLYELFSVMVHSGSAAGGHYYACIKSF 510
           8666666678888888888999999999999999999999999999999999999999999***************************6 PP
   S: 303  kgk.WllfdDskVtevkeeevleetg................staYvlfYk 336
           +++ W+ f+D++V+ +++e++++++g                ++aY+l+Y+
   Q: 511  SDEqWYSFNDQHVSRITQEDIKKTHGgssgsrgyyssafassTNAYMLIYR 561
           5555*******************888************************8 PP

Organism

Monodelphis domestica

Protein Sequence
(Fasta)

MVPGEENQLV PKEDMFWRCR QSIFDEMKKK FSQIENAAEE PRVLCIIQDT TNSKTVNERI 60
TLNLPASTPL RKLFEDVANK VGYVNGTFDL VWGNGISATD MPLDHTSDKS LLDTNFEPGK 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGGTCCCGG GCGAGGAGAA CCAGCTCGTC CCAAAGGAGG TGAGTGGGAG CGGGAGCCAA 60
GGGGCCTGGC TAGGCCCGCG CTGCGGCCTC CGGCAGCGGG CCCGGCCTAG CCACGGGCCC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR001394--Peptidase_C19_UCH
IPR018200--USP_CS
IPR028889--USP_dom

PROSITE

PS00972--USP_1
PS00973--USP_2
PS50235--USP_3

Pfam

PF00443--UCH

Gene Ontology

GO:0005737--C:cytoplasm
GO:0019005--C:SCF ubiquitin ligase complex
GO:0004843--F:thiol-dependent ubiquitin-specific protease activity
GO:0006284--P:base-excision repair
GO:0034644--P:cellular response to UV
GO:0035520--P:monoubiquitinated protein deubiquitination
GO:0043154--P:negative regulation of cysteine-type endopeptidase activity involved in apoptotic process
GO:0010972--P:negative regulation of G2/M transition of mitotic cell cycle
GO:1902230--P:negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage
GO:0045892--P:negative regulation of transcription, DNA-templated
GO:0030307--P:positive regulation of cell growth
GO:0042981--P:regulation of apoptotic process
GO:0042493--P:response to drug
GO:0006511--P:ubiquitin-dependent protein catabolic process

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002228	Ailuropoda melanoleuca	94.04	0.00e+00	2482.00
IUUC-Apl-003486	Anas platyrhynchos	90.68	0.00e+00	2377.00
IUUC-Aca-005061	Anolis carolinensis	88.88	0.00e+00	2421.00
IUUC-Ame-011206	Astyanax mexicanus	81.44	0.00e+00	2126.00
IUUC-Bta-012942	Bos taurus	94.46	0.00e+00	2513.00
IUUC-Cel-018600	Caenorhabditis elegans	38.02	2.00e-122	434.00
IUUC-Cja-018950	Callithrix jacchus	95.39	0.00e+00	2332.00
IUUC-Cfa-020299	Canis familiaris	96.07	0.00e+00	2501.00
IUUC-Cpo-021943	Cavia porcellus	95.01	0.00e+00	2491.00
IUUC-Csa-023285	Chlorocebus sabaeus	94.47	0.00e+00	2480.00
IUUC-Cho-025006	Choloepus hoffmanni	87.63	0.00e+00	2153.00
IUUC-Cin-025145	Ciona intestinalis	40.26	0.00e+00	717.00
IUUC-Csv-025839	Ciona savignyi	49.92	2.00e-165	577.00
IUUC-Dre-027959	Danio rerio	81.81	0.00e+00	2085.00
IUUC-Dno-030023	Dasypus novemcinctus	92.65	0.00e+00	2385.00
IUUC-Dor-030994	Dipodomys ordii	95.25	0.00e+00	938.00
IUUC-Dme-031604	Drosophila melanogaster	49.91	2.00e-146	513.00
IUUC-Ete-032596	Echinops telfairi	79.51	0.00e+00	1278.00
IUUC-Eca-033913	Equus caballus	95.30	0.00e+00	2518.00
IUUC-Eeu-034518	Erinaceus europaeus	87.98	0.00e+00	2102.00
IUUC-Fca-035997	Felis catus	95.27	0.00e+00	2524.00
IUUC-Fal-037088	Ficedula albicollis	89.75	0.00e+00	2120.00
IUUC-Gmo-038920	Gadus morhua	78.55	0.00e+00	2045.00
IUUC-Gga-040953	Gallus gallus	89.83	0.00e+00	2395.00
IUUC-Gac-042400	Gasterosteus aculeatus	79.84	0.00e+00	2057.00
IUUC-Ggo-044820	Gorilla gorilla	93.23	0.00e+00	2420.00
IUUC-Hsa-046634	Homo sapiens	95.56	0.00e+00	2522.00
IUUC-Lch-050440	Latimeria chalumnae	86.69	0.00e+00	2308.00
IUUC-Loc-051904	Lepisosteus oculatus	85.81	0.00e+00	2262.00
IUUC-Laf-053760	Loxodonta africana	94.40	0.00e+00	2550.00
IUUC-Mcc-054637	Macaca mulatta	95.71	0.00e+00	2529.00
IUUC-Meu-056904	Macropus eugenii	98.68	0.00e+00	1742.00
IUUC-Mga-059556	Meleagris gallopavo	89.14	0.00e+00	2351.00
IUUC-Mmr-061192	Microcebus murinus	95.93	0.00e+00	2534.00
IUUC-Mmu-063726	Mus musculus	92.73	0.00e+00	2502.00
IUUC-Mpu-066014	Mustela putorius furo	95.76	0.00e+00	2487.00
IUUC-Mlu-067232	Myotis lucifugus	94.95	0.00e+00	2487.00
IUUC-Nle-069619	Nomascus leucogenys	94.33	0.00e+00	2476.00
IUUC-Opr-070224	Ochotona princeps	90.98	0.00e+00	1115.00
IUUC-Ont-071384	Oreochromis niloticus	81.45	0.00e+00	2103.00
IUUC-Oan-073208	Ornithorhynchus anatinus	89.77	0.00e+00	2417.00
IUUC-Ocu-074285	Oryctolagus cuniculus	95.56	0.00e+00	2529.00
IUUC-Ola-087051	Oryzias latipes	79.73	0.00e+00	2013.00
IUUC-Oga-088928	Otolemur garnettii	95.52	0.00e+00	2504.00
IUUC-Oar-090215	Ovis aries	95.03	0.00e+00	2518.00
IUUC-Ptr-091035	Pan troglodytes	95.56	0.00e+00	2524.00
IUUC-Pan-092377	Papio anubis	95.15	0.00e+00	2480.00
IUUC-Pfo-096722	Poecilia formosa	80.81	0.00e+00	2086.00
IUUC-Pab-098723	Pongo abelii	95.56	0.00e+00	2527.00
IUUC-Pca-100105	Procavia capensis	90.53	0.00e+00	2302.00
IUUC-Pva-102514	Pteropus vampyrus	96.04	0.00e+00	933.00
IUUC-Rno-105384	Rattus norvegicus	93.67	0.00e+00	2462.00
IUUC-Sha-106982	Sarcophilus harrisii	94.47	0.00e+00	2542.00
IUUC-Sar-113723	Sorex araneus	85.31	0.00e+00	921.00
IUUC-Ssc-115671	Sus scrofa	95.48	0.00e+00	2009.00
IUUC-Tgu-116722	Taeniopygia guttata	88.78	0.00e+00	2338.00
IUUC-Tru-118380	Takifugu rubripes	78.52	0.00e+00	2085.00
IUUC-Tsy-119646	Tarsius syrichta	89.35	0.00e+00	2293.00
IUUC-Tni-120762	Tetraodon nigroviridis	79.20	0.00e+00	2103.00
IUUC-Tbe-127861	Tupaia belangeri	93.19	0.00e+00	2312.00
IUUC-Ttr-129254	Tursiops truncatus	89.81	0.00e+00	1420.00
IUUC-Vpa-130141	Vicugna pacos	95.56	0.00e+00	1158.00
IUUC-Xtr-132700	Xenopus tropicalis	82.47	0.00e+00	2218.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence