iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Ate-010531

Ensembl Protein ID

CADATEAP00005383

UniProt Accession

Q0CL11; Q0CL11_ASPTN

Genbank Protein ID

EAU34692.1

Protein Name

Ubiquitinyl hydrolase 1

Genbank Nucleotide ID

CH476600

Gene Name

ATEG_05623

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
CADATEAG00005383	CADATEAT00005383	CADATEAP00005383

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
DUB/USP	3.40e-47	160.3	304	756
UBD/Alpha-Helix/UBA	2.10e-07	30.0	624	662

Active Site

Position(s)	Description	Evidence
313	Nucleophile	{ECO:0000256\|PIRSR:PIRSR016308-1}
711	Proton acceptor	{ECO:0000256\|PIRSR:PIRSR016308-1}

Domain Profile

DUB/USP

   S: 1    tGlkNlgNtCYmNSvLQcLsnipelrellle....kkkeklneenpkepkgellkslqklfeel................w...kskkkavsp 70
           tGl+NlgN+CY+ Sv+Qc++ +pe+++ + +          + +  + p +++ +++qkl   l                      ++k ++p
   Q: 304  TGLTNLGNSCYLSSVVQCIFDLPEFQRRYYHiveeP-----PYS--QVPAEDFETQMQKLADGLlsgrysrtdsdiassaHssePPHQKGIAP 389
           7******************************55441.....322..2344455555555555553333333333333322133356666**** PP
   S: 71   rellkalkkeaeefsgyeqqDaqEflaflldqleeelkkeknkpkeeeeeedkselsdeaeekkkkknkslisdlFqgqlksqikclecdnvs 163
           +++++ +++ +eefs+++qqDa Efl+++++ ++++                           +++  ++  +d F++ ++++++cl+     
   Q: 390  SMFKHLVGRGHEEFSTMRQQDAFEFLTHVFKLINRSK--------------------------HPEILPN-PVDSFNFIMEQRLQCLHFPAHR 455
           *******************************999876..........................5555555.5689*************99988 PP
   S: 164  sreepfldlslpvpgkeetkkeslqdcLesftkeeelegenkyycekckkkqeaekklklkklPevLilhLkRfsfseeqksrekinkkvefp 256
              ++  d + pv+ +      +l+dc+++ t+ee +e    ++c+ c +k   +k+ ++k+lP+ L+++  Rf  +  +++++k++  ve+ 
   Q: 456  LPASD--DPNAPVQFRPV----TLHDCMSASTAEEIVE----LSCPACGSKDGFSKRSSFKTLPQELVVNARRF--ELINWVPTKLDIPVEVS 536
           66666..44556666664....5**************9....9*******************************..6677************* PP
   S: 257  le.Ldlspfcts................................................................................. 267
           ++ Ld +p+++s                                                                                 
   Q: 537  DQpLDFTPYLSSglqegeellpetendasvdafvphqpsmdqllkygfsrgnndaegamnwlfahmddadidepikskqnaglkveqdpakva 629
           ************899999888888888888888887777777777777777777777777777777777777766666666666555555555 PP
   S: 268  ..................peekqke.........................................kkkYeLiavvvHsG.slssGHYvayvk 300
                             +     +                                         + +Y+L ++v+H+G s++ GHYva+v+
   Q: 630  mlgemgidvtraqmalaaT-----DgdvnraidwvfshpditeaadnqqsaadsagdpksegfdsrPARYQLRSIVCHKGaSVHAGHYVAFVR 717
           5555555555555555550.....055555555555555555555555666677777777777788*************************** PP
   S: 301  n.....ekgkWllfdDskVtevkeeevleetgstaYvlfYkr 337
           +     e  +W+ f+D+kV  v  ++++e++ + aY++f+ r
   Q: 718  KaipgqEGLSWVMFNDEKVVRV--DDIQEMK-KFAYLYFFSR 756
           *887644444*********999..5666643.79*****987 PP

UBD/Alpha-Helix/UBA

   S: 3    dedkleqlveMGFdreealqaLraannnleaAveyLldg 41
           d  k++ l eMG+d  +a+ aL+a+++++++A+++++++
   Q: 624  DPAKVAMLGEMGIDVTRAQMALAATDGDVNRAIDWVFSH 662
           677999999****************************97 PP

Organism

Aspergillus terreus

Protein Sequence
(Fasta)

MASCIHAASQ DLRPPSHSQA VYREDCTQCF DSIDDQGGLN VCLTCFNGGC TGDRDHASLH 60
FKRFGHPLVL NIKRSRKKVQ RDEPPQKISK LAIVAETEDD IYDTATRVSC YACADDNVDT 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGGCTTCCT GTATCCATGC CGCCTCTCAA GGTTAGCTCT TGACTGAAAT CATTATATGC 60
CCCTCTGCAT CTTCTTCTGT TAACAACCAT CCTGGAACAG ATCTACGGCC CCCGTCACAC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0378--Hydrolase
KW-0479--Metal-binding
KW-0645--Protease
KW-1185--Reference proteome
KW-0788--Thiol protease
KW-0833--Ubl conjugation pathway
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR001394--Peptidase_C19_UCH
IPR015940--UBA
IPR009060--UBA-like
IPR016652--Ubiquitinyl_hydrolase
IPR018200--USP_CS
IPR028889--USP_dom
IPR013083--Znf_RING/FYVE/PHD
IPR001607--Znf_UBP

PROSITE

PS50030--UBA
PS00972--USP_1
PS00973--USP_2
PS50235--USP_3
PS50271--ZF_UBP

Pfam

PF00627--UBA
PF00443--UCH
PF02148--zf-UBP

SMART

SM00165--UBA
SM00290--ZnF_UBP

Gene Ontology

GO:0004843--F:thiol-dependent ubiquitin-specific protease activity
GO:0008270--F:zinc ion binding
GO:0016579--P:protein deubiquitination
GO:0006511--P:ubiquitin-dependent protein catabolic process

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000394	Aegilops tauschii	31.56	7.00e-86	310.00
IUUC-Aml-002104	Ailuropoda melanoleuca	32.49	1.00e-110	392.00
IUUC-Atr-002580	Amborella trichopoda	32.41	4.00e-95	340.00
IUUC-Apl-003774	Anas platyrhynchos	33.09	7.00e-109	386.00
IUUC-Aca-005368	Anolis carolinensis	33.21	6.00e-115	406.00
IUUC-Aly-005727	Arabidopsis lyrata	31.93	4.00e-102	363.00
IUUC-Ath-006974	Arabidopsis thaliana	32.67	2.00e-103	368.00
IUUC-Ago-007890	Ashbya gossypii	31.41	2.00e-98	352.00
IUUC-Acl-008057	Aspergillus clavatus	66.36	0.00e+00	1012.00
IUUC-Afl-008547	Aspergillus flavus	66.27	0.00e+00	889.00
IUUC-Afu-008805	Aspergillus fumigatus	61.92	0.00e+00	890.00
IUUC-Ani-009441	Aspergillus nidulans	58.60	0.00e+00	784.00
IUUC-Ang-009720	Aspergillus niger	64.56	0.00e+00	1001.00
IUUC-Aor-010111	Aspergillus oryzae	67.76	0.00e+00	1096.00
IUUC-Ame-011893	Astyanax mexicanus	32.54	2.00e-89	322.00
IUUC-Bgr-012183	Blumeria graminis	50.94	0.00e+00	780.00
IUUC-Bta-013179	Bos taurus	32.33	4.00e-110	390.00
IUUC-Bci-013858	Botrytis cinerea	54.44	0.00e+00	860.00
IUUC-Bdi-014904	Brachypodium distachyon	32.84	4.00e-93	334.00
IUUC-Bol-015296	Brassica oleracea	32.88	7.00e-103	366.00
IUUC-Bra-017939	Brassica rapa	33.37	5.00e-105	373.00
IUUC-Cel-018625	Caenorhabditis elegans	29.09	6.00e-76	277.00
IUUC-Cja-019063	Callithrix jacchus	32.00	5.00e-107	380.00
IUUC-Cfa-020976	Canis familiaris	33.18	1.00e-113	402.00
IUUC-Cpo-022265	Cavia porcellus	33.02	2.00e-113	401.00
IUUC-Cre-022640	Chlamydomonas reinhardtii	39.15	2.00e-40	158.00
IUUC-Csa-024078	Chlorocebus sabaeus	31.49	1.00e-99	355.00
IUUC-Cho-024702	Choloepus hoffmanni	31.88	6.00e-68	250.00
IUUC-Cin-025411	Ciona intestinalis	30.22	2.00e-89	322.00
IUUC-Csv-026347	Ciona savignyi	30.22	6.00e-90	323.00
IUUC-Cgl-026667	Colletotrichum gloeosporioides	55.51	0.00e+00	798.00
IUUC-Cne-026831	Cryptococcus neoformans	41.76	1.00e-159	555.00
IUUC-Cme-027335	Cyanidioschyzon merolae	29.09	5.00e-73	267.00
IUUC-Dre-027982	Danio rerio	31.43	4.00e-93	334.00
IUUC-Dno-029034	Dasypus novemcinctus	32.80	6.00e-113	400.00
IUUC-Dor-030130	Dipodomys ordii	38.85	4.00e-46	177.00
IUUC-Dse-031467	Dothistroma septosporum	49.38	0.00e+00	748.00
IUUC-Dme-032075	Drosophila melanogaster	32.97	2.00e-102	364.00
IUUC-Ete-032865	Echinops telfairi	29.25	2.00e-86	311.00
IUUC-Eca-034059	Equus caballus	32.52	9.00e-110	389.00
IUUC-Eeu-035304	Erinaceus europaeus	35.71	7.00e-101	359.00
IUUC-Fca-035515	Felis catus	32.57	3.00e-111	394.00
IUUC-Fal-037271	Ficedula albicollis	33.54	5.00e-104	370.00
IUUC-Fox-037745	Fusarium oxysporum	54.41	0.00e+00	841.00
IUUC-Fso-038158	Fusarium solani	55.36	0.00e+00	847.00
IUUC-Gmo-039071	Gadus morhua	31.29	2.00e-97	348.00
IUUC-Ggr-040098	Gaeumannomyces graminis	54.27	0.00e+00	796.00
IUUC-Gga-040635	Gallus gallus	32.56	5.00e-113	400.00
IUUC-Gac-042528	Gasterosteus aculeatus	32.42	2.00e-102	365.00
IUUC-Gma-043614	Glycine max	32.64	2.00e-99	355.00
IUUC-Ggo-044602	Gorilla gorilla	32.64	7.00e-111	393.00
IUUC-Hsa-045959	Homo sapiens	32.64	7.00e-111	393.00
IUUC-Hvu-047563	Hordeum vulgare	36.16	5.00e-94	337.00
IUUC-Itr-048712	Ictidomys tridecemlineatus	32.64	1.00e-111	395.00
IUUC-Kpa-049156	Komagataella pastoris	37.97	5.00e-150	523.00
IUUC-Lch-049648	Latimeria chalumnae	32.42	5.00e-102	363.00
IUUC-Lpe-051523	Leersia perrieri	32.56	1.00e-95	342.00
IUUC-Loc-052072	Lepisosteus oculatus	30.44	5.00e-98	350.00
IUUC-Lma-053216	Leptosphaeria maculans	54.56	0.00e+00	830.00
IUUC-Laf-054327	Loxodonta africana	32.34	2.00e-110	391.00
IUUC-Mcc-055443	Macaca mulatta	32.52	3.00e-111	394.00
IUUC-Meu-056298	Macropus eugenii	31.79	1.00e-75	276.00
IUUC-Mor-057106	Magnaporthe oryzae	55.06	0.00e+00	845.00
IUUC-Mpo-057589	Magnaporthe poae	54.09	0.00e+00	798.00
IUUC-Mtr-058680	Medicago truncatula	33.25	3.00e-104	371.00
IUUC-Mla-058903	Melampsora laricipopulina	40.17	7.00e-154	536.00
IUUC-Mga-059669	Meleagris gallopavo	32.90	1.00e-105	375.00
IUUC-Mvi-060476	Microbotryum violaceum	40.99	4.00e-144	503.00
IUUC-Mmr-060575	Microcebus murinus	32.80	2.00e-111	395.00
IUUC-Mdo-062183	Monodelphis domestica	32.47	1.00e-110	392.00
IUUC-Mmu-063592	Mus musculus	32.68	3.00e-111	394.00
IUUC-Mac-065634	Musa acuminata	30.65	3.00e-91	327.00
IUUC-Mpu-066082	Mustela putorius furo	33.18	7.00e-113	399.00
IUUC-Mlu-067345	Myotis lucifugus	33.03	3.00e-112	397.00
IUUC-Nfi-068558	Neosartorya fischeri	65.18	0.00e+00	963.00
IUUC-Ncr-068960	Neurospora crassa	56.01	0.00e+00	827.00
IUUC-Nle-070173	Nomascus leucogenys	33.13	2.00e-112	398.00
IUUC-Opr-070556	Ochotona princeps	33.03	3.00e-112	397.00
IUUC-Ont-071502	Oreochromis niloticus	33.01	3.00e-102	364.00
IUUC-Oan-072959	Ornithorhynchus anatinus	47.45	3.00e-46	176.00
IUUC-Ocu-074861	Oryctolagus cuniculus	33.18	4.00e-113	400.00
IUUC-Oba-075109	Oryza barthii	32.84	3.00e-99	354.00
IUUC-Obr-076292	Oryza brachyantha	33.21	1.00e-94	339.00
IUUC-Ogl-077065	Oryza glaberrima	33.78	2.00e-105	375.00
IUUC-Ogu-078776	Oryza glumaepatula	33.09	2.00e-102	364.00
IUUC-Oin-080048	Oryza indica	33.78	2.00e-105	374.00
IUUC-Olo-080711	Oryza longistaminata	32.48	3.00e-90	324.00
IUUC-Ome-081506	Oryza meridionalis	33.20	4.00e-93	333.00
IUUC-Oni-082320	Oryza nivara	36.01	3.00e-93	334.00
IUUC-Opu-083801	Oryza punctata	32.68	2.00e-93	335.00
IUUC-Oru-085139	Oryza rufipogon	32.42	1.00e-98	352.00
IUUC-Osa-085713	Oryza sativa	33.78	4.00e-106	377.00
IUUC-Ola-086951	Oryzias latipes	31.54	3.00e-99	354.00
IUUC-Olu-087822	Ostreococcus lucimarinus	30.93	4.00e-85	307.00
IUUC-Oga-088625	Otolemur garnettii	32.34	2.00e-110	391.00
IUUC-Oar-089995	Ovis aries	32.33	7.00e-110	389.00
IUUC-Ptr-090640	Pan troglodytes	33.17	1.00e-112	399.00
IUUC-Pan-091974	Papio anubis	32.52	7.00e-111	393.00
IUUC-Psi-093957	Pelodiscus sinensis	32.94	1.00e-113	402.00
IUUC-Pma-094242	Petromyzon marinus	37.37	2.00e-61	227.00
IUUC-Pno-094835	Phaeosphaeria nodorum	53.68	0.00e+00	727.00
IUUC-Ppa-095901	Physcomitrella patens	33.01	5.00e-108	383.00
IUUC-Pfo-097148	Poecilia formosa	33.25	2.00e-105	374.00
IUUC-Pab-098068	Pongo abelii	30.79	4.00e-93	334.00
IUUC-Pop-098855	Populus trichocarpa	32.72	4.00e-102	363.00
IUUC-Pca-100738	Procavia capensis	33.33	4.00e-81	294.00
IUUC-Ppe-101315	Prunus persica	31.04	2.00e-96	345.00
IUUC-Pva-102154	Pteropus vampyrus	32.10	5.00e-109	387.00
IUUC-Pgr-103343	Puccinia graminis	40.45	9.00e-132	462.00
IUUC-Ptt-103928	Puccinia triticina	34.26	1.00e-122	432.00
IUUC-Pte-104306	Pyrenophora teres	54.33	0.00e+00	770.00
IUUC-Pyt-104696	Pyrenophora triticirepentis	54.16	0.00e+00	802.00
IUUC-Rno-105801	Rattus norvegicus	33.14	3.00e-112	397.00
IUUC-Sce-106304	Saccharomyces cerevisiae	32.75	2.00e-103	368.00
IUUC-Sha-107635	Sarcophilus harrisii	32.58	1.00e-110	392.00
IUUC-Sja-107678	Schizosaccharomyces japonicus	39.62	4.00e-150	523.00
IUUC-Spo-108144	Schizosaccharomyces pombe	37.39	2.00e-148	517.00
IUUC-Smo-108848	Selaginella moellendorffii	34.70	1.00e-100	358.00
IUUC-Sit-110728	Setaria italica	32.80	5.00e-103	367.00
IUUC-Sly-111523	Solanum lycopersicum	32.63	4.00e-106	377.00
IUUC-Sar-113733	Sorex araneus	36.01	3.00e-60	224.00
IUUC-Sbi-114419	Sorghum bicolor	33.05	5.00e-101	360.00
IUUC-Sre-115225	Sporisorium reilianum	39.64	4.00e-152	530.00
IUUC-Ssc-115686	Sus scrofa	32.48	6.00e-111	393.00
IUUC-Tgu-117346	Taeniopygia guttata	32.68	4.00e-107	380.00
IUUC-Tru-118350	Takifugu rubripes	30.42	3.00e-99	354.00
IUUC-Tsy-119278	Tarsius syrichta	30.49	9.00e-82	296.00
IUUC-Tni-120658	Tetraodon nigroviridis	31.38	1.00e-95	342.00
IUUC-Tca-121585	Theobroma cacao	33.05	2.00e-99	355.00
IUUC-Tre-122043	Trichoderma reesei	54.76	0.00e+00	808.00
IUUC-Tvi-122303	Trichoderma virens	54.31	0.00e+00	834.00
IUUC-Tae-123798	Triticum aestivum	32.89	6.00e-100	357.00
IUUC-Tur-126732	Triticum urartu	30.87	7.00e-89	320.00
IUUC-Tme-126909	Tuber melanosporum	52.99	0.00e+00	801.00
IUUC-Tbe-127699	Tupaia belangeri	33.24	2.00e-44	172.00
IUUC-Ttr-128295	Tursiops truncatus	28.96	3.00e-78	284.00
IUUC-Uma-129599	Ustilago maydis	39.57	2.00e-153	535.00
IUUC-Vda-129688	Verticillium dahliae	54.26	0.00e+00	798.00
IUUC-Vpa-130170	Vicugna pacos	36.06	5.00e-49	187.00
IUUC-Vvi-131116	Vitis vinifera	32.51	1.00e-99	356.00
IUUC-Xtr-131953	Xenopus tropicalis	31.12	1.00e-93	335.00
IUUC-Xma-133837	Xiphophorus maculatus	33.25	3.00e-105	374.00
IUUC-Yli-134510	Yarrowia lipolytica	40.83	1.00e-146	511.00
IUUC-Zma-135786	Zea mays	33.25	2.00e-94	338.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence