iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Ggr-040098

Ensembl Protein ID

GGTG_09765T0

UniProt Accession

J3P8D1; J3P8D1_GAGT3

Genbank Protein ID

EJT72914.1

Protein Name

Ubiquitinyl hydrolase 1

Genbank Nucleotide ID

ADBI01000793

Gene Name

GGTG_09765

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
GGTG_09765	GGTG_09765T0	GGTG_09765T0

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
DUB/USP	1.20e-49	168.9	301	790
UBD/Alpha-Helix/UBA	1.60e-22	78.5	594	632

Active Site

Position(s)	Description	Evidence
310	Nucleophile	{ECO:0000256\|PIRSR:PIRSR016308-1}
745	Proton acceptor	{ECO:0000256\|PIRSR:PIRSR016308-1}

Domain Profile

DUB/USP

   S: 1    tGlkNlgNtCYmNSvLQcLsnipelrelllekkkeklneenpkepkgellkslqklfeel.........wkskkk..............avsprell 74
           tGlkNlgN+CY+ S+LQcL++++++++ + +  +++l     ++p ++l ++l+k+   l         +                     +p++l+
   Q: 301  TGLKNLGNSCYLASILQCLFQMESFQKRYGQ-VTQDLVGV--QDPAQDLETQLRKIGDGLlsgryskpdT----DvvvsehsteiphqkGLQPSMLK 390
           7******************************.77777766..78999***********995555555550....0444444455555559******* PP
   S: 75   kalkkeaeefsgyeqqDaqEflaflldqleeelkkeknkpkeeeeeedkselsdeaeekkkkknkslisdlFqgqlksqikclecdnvssreepfld 171
           + +++ +eefs+++qqDa E+l++l++ + ++                            + +  +  +  F++ l+++++cl+c++v  ++++  +
   Q: 391  HLIGRGHEEFSTMRQQDAFELLQHLIKMITRSK---------------------------HPSPADDPTLPFRFILEQRLQCLSCKKVRYTTNEQDS 460
           ***************************999877...........................34445556789******************999999** PP
   S: 172  lslpvpgkeetkke...............slqdcLesftkeeelegenkyycekckkkqeaekklklkklPevLilhLkRfsfseeqksrekinkkv 253
           + ++vp ++  ++                +l++cL+  t ee++e    + c+ c +k   +k+  +k+lP+vL+++  ++  +  ++++ k++  v
   Q: 461  IFIDVPLEKLPETDggdkdsntggsykpvTLTECLDRLTGEETVE----LTCSACGSKDGYVKRSLFKTLPKVLVVNARKM--TVINWVPVKVDVPV 551
           ******999776669999**************************9....9*******************************..5577********** PP
   S: 254  efple.Ldlspfctspeekqke........................................................................... 274
            +++    l++++++ +++++e                                                                           
   Q: 552  IVNDDpYLLDQYLSKGQQADEEslpedagpsasgsapafvpnaealaqleamgfprnrcekglhatgngdanaamewlfqhmedpnideplfipsgg 648
           ***99999999****5555544666666666666666666666666666677777777777777777777777777777777777777777777777 PP
   S: 275  ............................................................................kkkYeLiavvvHsG.slssGH 294
                                                                                       + k++L ++v+H+G s++ GH
   Q: 649  ggsagggafvadpssiemlgamgfgekkatkalketggdleravewlfshpeddgtmeaevestgperpaagssdtPAKFQLQSIVCHKGtSIHAGH 745
           7777777777777777777777777777777778888888888888888888888888888888888888889989********************* PP
   S: 295  Yvayvkn...ekgk....WllfdDskVtev.keeevleetgstaYvlfYkr 337
           Yva++++   +  +    W+lf+D+kV +v + ee+++     aYv+f++r
   Q: 746  YVAFIRKqleN--EgslsWVLFNDEKVVQVvDVEEMKK----FAYVYFFNR 790
           *******5543..14588********977724566655....8*****986 PP

UBD/Alpha-Helix/UBA

   S: 4    edkleqlveMGFdreealqaLraa.nnnleaAveyLldg 41
            ++l+ql++MGF+r+++ + L a+ n++++aA+e+L+ +
   Q: 594  AEALAQLEAMGFPRNRCEKGLHATgNGDANAAMEWLFQH 632
           689*********************************976 PP

Organism

Gaeumannomyces graminis

Protein Sequence
(Fasta)

MTCSHLETLS LRAPTPTQSV YREDCTQCFD SIDDPEGLDV CLQCFNGGCT GERHHAKLHN 60
VVWGHPIVLN VRRTRKFVDR DEPPPKMSKL AIAAETETDR YTTTLVVKCL ECNVELDKNH 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CCAGGTAAAC GGCCAACGGG AAGCGGCTCG CTCAGATTTA TCAGCTCTTC CCTCCCAACA 60
TCCTGCCGTC CTTTTCCATC TCCACAGCTC CCACTGGCAT CACGACCTCT CTTAGGCAAG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0378--Hydrolase
KW-0479--Metal-binding
KW-0645--Protease
KW-1185--Reference proteome
KW-0788--Thiol protease
KW-0833--Ubl conjugation pathway
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR001394--Peptidase_C19_UCH
IPR015940--UBA
IPR009060--UBA-like
IPR016652--Ubiquitinyl_hydrolase
IPR018200--USP_CS
IPR028889--USP_dom
IPR013083--Znf_RING/FYVE/PHD
IPR001607--Znf_UBP

PROSITE

PS50030--UBA
PS00972--USP_1
PS00973--USP_2
PS50235--USP_3
PS50271--ZF_UBP

Pfam

PF00627--UBA
PF00443--UCH
PF02148--zf-UBP

SMART

SM00165--UBA
SM00290--ZnF_UBP

Gene Ontology

GO:0004843--F:thiol-dependent ubiquitin-specific protease activity
GO:0008270--F:zinc ion binding
GO:0016579--P:protein deubiquitination
GO:0006511--P:ubiquitin-dependent protein catabolic process

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000394	Aegilops tauschii	32.57	6.00e-99	353.00
IUUC-Aml-002104	Ailuropoda melanoleuca	34.61	2.00e-126	444.00
IUUC-Atr-002580	Amborella trichopoda	33.30	2.00e-108	385.00
IUUC-Apl-003774	Anas platyrhynchos	34.92	4.00e-126	443.00
IUUC-Aca-005368	Anolis carolinensis	35.04	9.00e-133	466.00
IUUC-Aly-005727	Arabidopsis lyrata	35.91	3.00e-123	434.00
IUUC-Ath-006974	Arabidopsis thaliana	36.40	9.00e-125	439.00
IUUC-Ago-007890	Ashbya gossypii	31.49	3.00e-105	374.00
IUUC-Acl-008057	Aspergillus clavatus	56.08	0.00e+00	889.00
IUUC-Afl-008547	Aspergillus flavus	57.78	0.00e+00	808.00
IUUC-Afu-008805	Aspergillus fumigatus	52.51	0.00e+00	789.00
IUUC-Ani-009441	Aspergillus nidulans	52.04	0.00e+00	726.00
IUUC-Ang-009720	Aspergillus niger	57.11	0.00e+00	898.00
IUUC-Aor-010111	Aspergillus oryzae	57.81	0.00e+00	956.00
IUUC-Ate-010531	Aspergillus terreus	53.96	0.00e+00	837.00
IUUC-Ame-011893	Astyanax mexicanus	35.44	7.00e-108	383.00
IUUC-Bgr-012183	Blumeria graminis	60.42	0.00e+00	979.00
IUUC-Bta-013179	Bos taurus	34.76	1.00e-125	442.00
IUUC-Bci-013858	Botrytis cinerea	65.45	0.00e+00	1065.00
IUUC-Bdi-014904	Brachypodium distachyon	33.82	4.00e-103	367.00
IUUC-Bol-015536	Brassica oleracea	36.26	5.00e-121	427.00
IUUC-Bra-017939	Brassica rapa	36.47	3.00e-122	431.00
IUUC-Cel-018625	Caenorhabditis elegans	30.47	3.00e-84	304.00
IUUC-Cja-019063	Callithrix jacchus	34.14	6.00e-122	430.00
IUUC-Cfa-020976	Canis familiaris	35.71	5.00e-130	457.00
IUUC-Cpo-022265	Cavia porcellus	35.43	3.00e-129	454.00
IUUC-Cre-022640	Chlamydomonas reinhardtii	32.43	5.00e-68	250.00
IUUC-Csa-024177	Chlorocebus sabaeus	35.71	9.00e-117	412.00
IUUC-Cho-024702	Choloepus hoffmanni	32.99	9.00e-75	273.00
IUUC-Cin-025411	Ciona intestinalis	33.01	8.00e-103	366.00
IUUC-Csv-026347	Ciona savignyi	32.10	5.00e-102	363.00
IUUC-Cgl-026667	Colletotrichum gloeosporioides	71.18	0.00e+00	1102.00
IUUC-Cne-026831	Cryptococcus neoformans	45.52	1.00e-180	625.00
IUUC-Cme-027335	Cyanidioschyzon merolae	34.18	3.00e-59	222.00
IUUC-Dre-027982	Danio rerio	33.26	5.00e-109	387.00
IUUC-Dno-029034	Dasypus novemcinctus	34.87	2.00e-128	451.00
IUUC-Dor-030130	Dipodomys ordii	35.71	2.00e-53	202.00
IUUC-Dse-031467	Dothistroma septosporum	55.20	0.00e+00	858.00
IUUC-Dme-032075	Drosophila melanogaster	33.49	2.00e-113	401.00
IUUC-Ete-032865	Echinops telfairi	32.02	5.00e-106	377.00
IUUC-Eca-034059	Equus caballus	34.64	4.00e-125	440.00
IUUC-Eeu-035304	Erinaceus europaeus	36.99	9.00e-116	409.00
IUUC-Fca-035515	Felis catus	34.64	4.00e-126	444.00
IUUC-Fal-037271	Ficedula albicollis	35.41	2.00e-123	435.00
IUUC-Fox-037745	Fusarium oxysporum	70.20	0.00e+00	1127.00
IUUC-Fso-038158	Fusarium solani	71.54	0.00e+00	1135.00
IUUC-Gmo-039071	Gadus morhua	34.65	2.00e-112	398.00
IUUC-Gga-040635	Gallus gallus	33.79	1.00e-127	449.00
IUUC-Gac-042528	Gasterosteus aculeatus	34.57	2.00e-116	412.00
IUUC-Gma-043614	Glycine max	34.58	5.00e-110	390.00
IUUC-Ggo-044602	Gorilla gorilla	34.76	8.00e-126	442.00
IUUC-Hsa-045959	Homo sapiens	34.76	8.00e-126	442.00
IUUC-Hvu-047563	Hordeum vulgare	36.23	3.00e-102	364.00
IUUC-Itr-048712	Ictidomys tridecemlineatus	34.72	1.00e-126	445.00
IUUC-Kpa-049156	Komagataella pastoris	40.20	3.00e-170	590.00
IUUC-Lch-049648	Latimeria chalumnae	34.25	8.00e-123	432.00
IUUC-Lpe-051523	Leersia perrieri	32.97	2.00e-104	371.00
IUUC-Loc-052072	Lepisosteus oculatus	32.63	1.00e-109	389.00
IUUC-Lma-053216	Leptosphaeria maculans	63.34	0.00e+00	970.00
IUUC-Laf-054327	Loxodonta africana	34.64	3.00e-126	444.00
IUUC-Mcc-055443	Macaca mulatta	34.76	3.00e-126	444.00
IUUC-Meu-056298	Macropus eugenii	34.54	3.00e-86	311.00
IUUC-Mor-057106	Magnaporthe oryzae	79.65	0.00e+00	1281.00
IUUC-Mpo-057589	Magnaporthe poae	93.32	0.00e+00	1446.00
IUUC-Mtr-058680	Medicago truncatula	35.03	4.00e-113	400.00
IUUC-Mla-058903	Melampsora laricipopulina	42.65	1.00e-179	621.00
IUUC-Mga-059669	Meleagris gallopavo	34.56	2.00e-120	425.00
IUUC-Mvi-060476	Microbotryum violaceum	44.24	5.00e-177	612.00
IUUC-Mmr-060575	Microcebus murinus	34.64	8.00e-126	442.00
IUUC-Mdo-062183	Monodelphis domestica	35.29	8.00e-127	446.00
IUUC-Mmu-063592	Mus musculus	34.37	3.00e-126	444.00
IUUC-Mac-065446	Musa acuminata	31.64	5.00e-95	340.00
IUUC-Mpu-066082	Mustela putorius furo	35.71	7.00e-130	456.00
IUUC-Mlu-067345	Myotis lucifugus	34.56	1.00e-125	442.00
IUUC-Nfi-068558	Neosartorya fischeri	55.20	0.00e+00	855.00
IUUC-Ncr-068960	Neurospora crassa	72.27	0.00e+00	1106.00
IUUC-Nle-070173	Nomascus leucogenys	35.59	2.00e-128	451.00
IUUC-Opr-070556	Ochotona princeps	35.23	2.00e-126	445.00
IUUC-Ont-071502	Oreochromis niloticus	35.61	6.00e-117	413.00
IUUC-Oan-072959	Ornithorhynchus anatinus	41.96	4.00e-48	182.00
IUUC-Ocu-074861	Oryctolagus cuniculus	36.07	6.00e-129	453.00
IUUC-Oba-075109	Oryza barthii	32.93	1.00e-106	379.00
IUUC-Obr-076292	Oryza brachyantha	33.94	2.00e-102	365.00
IUUC-Ogl-077065	Oryza glaberrima	33.33	2.00e-112	398.00
IUUC-Ogu-078776	Oryza glumaepatula	32.80	7.00e-110	389.00
IUUC-Oin-080048	Oryza indica	33.33	4.00e-111	394.00
IUUC-Olo-080711	Oryza longistaminata	32.11	6.00e-99	353.00
IUUC-Ome-081506	Oryza meridionalis	32.81	2.00e-100	358.00
IUUC-Oni-082320	Oryza nivara	31.79	2.00e-103	369.00
IUUC-Opu-083801	Oryza punctata	32.97	2.00e-100	358.00
IUUC-Oru-085139	Oryza rufipogon	32.02	1.00e-104	372.00
IUUC-Osa-085713	Oryza sativa	33.33	2.00e-113	401.00
IUUC-Ola-086951	Oryzias latipes	33.96	6.00e-111	393.00
IUUC-Olu-087822	Ostreococcus lucimarinus	31.96	1.00e-95	343.00
IUUC-Oga-088625	Otolemur garnettii	34.41	8.00e-126	442.00
IUUC-Oar-089995	Ovis aries	34.53	4.00e-125	440.00
IUUC-Ptr-090640	Pan troglodytes	35.60	2.00e-128	451.00
IUUC-Pan-091974	Papio anubis	34.60	4.00e-126	444.00
IUUC-Psi-093957	Pelodiscus sinensis	33.60	2.00e-127	448.00
IUUC-Pma-094242	Petromyzon marinus	39.22	7.00e-69	252.00
IUUC-Pno-094835	Phaeosphaeria nodorum	60.88	0.00e+00	868.00
IUUC-Ppa-095901	Physcomitrella patens	36.03	2.00e-123	434.00
IUUC-Pfo-097148	Poecilia formosa	35.65	5.00e-118	417.00
IUUC-Pab-098068	Pongo abelii	32.14	6.00e-105	373.00
IUUC-Pop-098855	Populus trichocarpa	33.66	3.00e-109	387.00
IUUC-Pca-100738	Procavia capensis	35.62	5.00e-90	324.00
IUUC-Ppe-101315	Prunus persica	33.98	5.00e-111	393.00
IUUC-Pva-102154	Pteropus vampyrus	33.91	4.00e-124	437.00
IUUC-Pgr-103343	Puccinia graminis	42.03	2.00e-148	518.00
IUUC-Ptt-103928	Puccinia triticina	37.00	1.00e-144	505.00
IUUC-Pte-104306	Pyrenophora teres	63.24	0.00e+00	931.00
IUUC-Pyt-104696	Pyrenophora triticirepentis	62.47	0.00e+00	945.00
IUUC-Rno-105801	Rattus norvegicus	34.49	8.00e-127	446.00
IUUC-Sce-106304	Saccharomyces cerevisiae	32.17	7.00e-107	380.00
IUUC-Sha-107635	Sarcophilus harrisii	35.32	9.00e-128	449.00
IUUC-Sja-107678	Schizosaccharomyces japonicus	42.48	1.00e-175	608.00
IUUC-Spo-108144	Schizosaccharomyces pombe	42.45	4.00e-180	623.00
IUUC-Smo-108703	Selaginella moellendorffii	36.17	4.00e-114	404.00
IUUC-Sit-110728	Setaria italica	33.50	6.00e-113	400.00
IUUC-Sly-111523	Solanum lycopersicum	34.96	4.00e-120	424.00
IUUC-Sar-113733	Sorex araneus	39.74	1.00e-59	223.00
IUUC-Sbi-114419	Sorghum bicolor	33.98	3.00e-112	397.00
IUUC-Sre-115225	Sporisorium reilianum	44.19	0.00e+00	630.00
IUUC-Ssc-115686	Sus scrofa	34.72	2.00e-126	444.00
IUUC-Tgu-117346	Taeniopygia guttata	33.60	5.00e-125	440.00
IUUC-Tru-118350	Takifugu rubripes	33.33	2.00e-111	395.00
IUUC-Tsy-119278	Tarsius syrichta	34.41	3.00e-89	321.00
IUUC-Tni-120658	Tetraodon nigroviridis	33.84	8.00e-109	386.00
IUUC-Tca-121585	Theobroma cacao	34.71	2.00e-108	384.00
IUUC-Tre-122043	Trichoderma reesei	69.14	0.00e+00	1083.00
IUUC-Tvi-122303	Trichoderma virens	69.94	0.00e+00	1085.00
IUUC-Tae-123798	Triticum aestivum	34.26	2.00e-112	398.00
IUUC-Tur-126732	Triticum urartu	32.15	4.00e-102	363.00
IUUC-Tme-126909	Tuber melanosporum	59.20	0.00e+00	915.00
IUUC-Tbe-127261	Tupaia belangeri	30.61	7.00e-71	260.00
IUUC-Ttr-128295	Tursiops truncatus	28.92	2.00e-87	315.00
IUUC-Uma-129599	Ustilago maydis	43.02	0.00e+00	644.00
IUUC-Vda-129688	Verticillium dahliae	69.81	0.00e+00	1085.00
IUUC-Vpa-130170	Vicugna pacos	30.14	2.00e-74	272.00
IUUC-Vvi-131116	Vitis vinifera	34.10	8.00e-110	389.00
IUUC-Xtr-131953	Xenopus tropicalis	33.84	5.00e-114	404.00
IUUC-Xma-133837	Xiphophorus maculatus	35.41	2.00e-117	415.00
IUUC-Yli-134510	Yarrowia lipolytica	44.83	6.00e-175	606.00
IUUC-Zma-135786	Zea mays	33.62	1.00e-105	375.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence