iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Ola-086891

Ensembl Protein ID

ENSORLP00000022617.2

UniProt Accession

H2MUZ5; H2MUZ5_ORYLA

Genbank Protein ID

ENSORLP00000022617

Protein Name

Inhibitor of growth protein

Genbank Nucleotide ID

BAAF04024006

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSORLG00000018057.2	ENSORLT00000022618.2	ENSORLP00000022617.2
ENSORLG00000018057.2	ENSORLT00000022615.1	ENSORLP00000022614.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/RING/PHD	2.40e-08	34.3	211	258

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 activity/RING/PHD

   S: 2    kvClvCgeggedekslveCek..Cr.ewfHpaClklsveeelpnsekwiCpkCrs 53
           ++C +C++ + +e  ++ C++  C  ewfH+ C++l     +p+ + w+CpkCr 
   Q: 211  TYC-LCEQVSYGE--MIGCDNdeCPiEWFHFSCVGLH---HKPKGK-WYCPKCRG 258
           69*.*******99..******9**99***********...999997.******85 PP

Organism

Oryzias latipes

Protein Sequence
(Fasta)

MLNSANGDPG HVVVNYVEEY LDLVESLPFD LQRSVSLMRE IDAKYQDVLK ELDDAYERYR 60
RESDSLQRRK LQLSIQRALI RSQELGDEKI QIAGQMVEMV ENRTRQIDWH SELLLSSQEV 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GTTCTGCACG TCAACAAACT AGCATTAGCA AAGCTGCAAC AGAATTCCAG AGGTTTGCTA 60
CAAATATATT AAAACAATAC AGGTATACCC AAAGGTATGG TTTTGTATAA CCAGCTACTT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0156--Chromatin regulator
KW-0175--Coiled coil
KW-0181--Complete proteome
KW-0479--Metal-binding
KW-0539--Nucleus
KW-1185--Reference proteome
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR028643--ING1
IPR028651--ING_fam
IPR024610--ING_N_histone_binding
IPR019786--Zinc_finger_PHD-type_CS
IPR011011--Znf_FYVE_PHD
IPR001965--Znf_PHD
IPR019787--Znf_PHD-finger
IPR013083--Znf_RING/FYVE/PHD

PROSITE

PS01359--ZF_PHD_1
PS50016--ZF_PHD_2

Pfam

PF12998--ING

SMART

SM01408--ING
SM00249--PHD

Gene Ontology

GO:0005634--C:nucleus
GO:0008270--F:zinc ion binding
GO:0016569--P:covalent chromatin modification
GO:0008285--P:negative regulation of cell proliferation
GO:0010941--P:regulation of cell death

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001945	Ailuropoda melanoleuca	62.86	8.00e-90	323.00
IUUC-Apl-003910	Anas platyrhynchos	62.72	6.00e-90	323.00
IUUC-Aca-004874	Anolis carolinensis	61.79	1.00e-88	319.00
IUUC-Acl-008091	Aspergillus clavatus	49.30	1.00e-17	85.10
IUUC-Ame-011262	Astyanax mexicanus	64.97	3.00e-92	331.00
IUUC-Bta-013507	Bos taurus	58.80	2.00e-64	238.00
IUUC-Cja-018925	Callithrix jacchus	65.36	9.00e-89	319.00
IUUC-Cfa-020663	Canis familiaris	61.43	3.00e-87	314.00
IUUC-Cpo-022286	Cavia porcellus	58.90	2.00e-67	248.00
IUUC-Csa-023825	Chlorocebus sabaeus	65.36	8.00e-89	319.00
IUUC-Cho-024577	Choloepus hoffmanni	59.66	1.00e-68	252.00
IUUC-Cne-027005	Cryptococcus neoformans	49.25	9.00e-17	80.90
IUUC-Dre-028562	Danio rerio	58.65	4.00e-76	277.00
IUUC-Dno-029834	Dasypus novemcinctus	62.86	2.00e-89	321.00
IUUC-Dor-030315	Dipodomys ordii	64.38	7.00e-75	274.00
IUUC-Dse-031323	Dothistroma septosporum	51.35	4.00e-18	86.70
IUUC-Ete-032408	Echinops telfairi	62.98	6.00e-65	241.00
IUUC-Eca-034244	Equus caballus	60.26	4.00e-69	253.00
IUUC-Fca-035391	Felis catus	58.75	5.00e-73	267.00
IUUC-Fal-036838	Ficedula albicollis	62.86	1.00e-90	325.00
IUUC-Fox-037925	Fusarium oxysporum	69.57	1.00e-19	90.90
IUUC-Gmo-038557	Gadus morhua	75.27	2.00e-95	342.00
IUUC-Gga-040619	Gallus gallus	63.21	1.00e-90	325.00
IUUC-Gac-041996	Gasterosteus aculeatus	88.57	5.00e-128	449.00
IUUC-Ggo-045481	Gorilla gorilla	63.14	2.00e-68	252.00
IUUC-Hsa-046170	Homo sapiens	63.14	2.00e-68	252.00
IUUC-Itr-048440	Ictidomys tridecemlineatus	59.83	6.00e-69	253.00
IUUC-Lch-050397	Latimeria chalumnae	66.43	1.00e-90	325.00
IUUC-Loc-052038	Lepisosteus oculatus	66.41	3.00e-82	297.00
IUUC-Lma-053234	Leptosphaeria maculans	53.45	6.00e-16	79.30
IUUC-Laf-054126	Loxodonta africana	63.57	1.00e-90	325.00
IUUC-Mcc-055031	Macaca mulatta	62.98	1.00e-67	249.00
IUUC-Meu-056248	Macropus eugenii	63.03	2.00e-68	252.00
IUUC-Mga-059217	Meleagris gallopavo	60.34	2.00e-69	254.00
IUUC-Mmr-061581	Microcebus murinus	61.32	6.00e-74	270.00
IUUC-Mdo-062452	Monodelphis domestica	62.50	3.00e-89	321.00
IUUC-Mmu-063412	Mus musculus	65.36	2.00e-88	318.00
IUUC-Mpu-066479	Mustela putorius furo	60.26	4.00e-69	254.00
IUUC-Mlu-067586	Myotis lucifugus	55.32	6.00e-81	293.00
IUUC-Nle-069122	Nomascus leucogenys	66.07	1.00e-89	322.00
IUUC-Opr-070835	Ochotona princeps	63.09	2.00e-64	238.00
IUUC-Ont-071606	Oreochromis niloticus	81.05	3.00e-120	424.00
IUUC-Oan-073023	Ornithorhynchus anatinus	63.21	6.00e-89	320.00
IUUC-Ocu-073779	Oryctolagus cuniculus	62.08	6.00e-68	250.00
IUUC-Olu-087851	Ostreococcus lucimarinus	65.38	2.00e-18	85.50
IUUC-Oga-087954	Otolemur garnettii	62.14	1.00e-87	315.00
IUUC-Oar-090006	Ovis aries	61.65	4.00e-88	317.00
IUUC-Ptr-090589	Pan troglodytes	65.71	3.00e-89	321.00
IUUC-Pan-091896	Papio anubis	62.98	1.00e-67	250.00
IUUC-Psi-093266	Pelodiscus sinensis	63.93	5.00e-91	327.00
IUUC-Pma-094265	Petromyzon marinus	74.39	1.00e-34	138.00
IUUC-Pfo-097531	Poecilia formosa	82.41	9.00e-130	456.00
IUUC-Pab-098253	Pongo abelii	65.71	3.00e-89	321.00
IUUC-Pva-102753	Pteropus vampyrus	55.00	3.00e-59	222.00
IUUC-Rno-105964	Rattus norvegicus	63.68	4.00e-67	247.00
IUUC-Sha-107270	Sarcophilus harrisii	62.86	2.00e-89	322.00
IUUC-Tgu-116822	Taeniopygia guttata	63.21	4.00e-91	327.00
IUUC-Tru-118262	Takifugu rubripes	76.62	3.00e-103	367.00
IUUC-Tni-119980	Tetraodon nigroviridis	80.39	1.00e-110	392.00
IUUC-Tre-121950	Trichoderma reesei	64.29	2.00e-19	90.90
IUUC-Ttr-128672	Tursiops truncatus	60.68	2.00e-70	258.00
IUUC-Xtr-132200	Xenopus tropicalis	61.79	6.00e-87	313.00
IUUC-Xma-133491	Xiphophorus maculatus	83.55	3.00e-129	454.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence