iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Aca-004447

UUCD1 version

UUC-AnC-00149

Ensembl Protein ID

ENSACAP00000006948.3

UniProt Accession

H9GCA4; H9GCA4_ANOCA

Protein Name

Uncharacterized protein

Gene Name

RNF112

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSACAG00000007106.3	ENSACAT00000007099.3	ENSACAP00000006948.3

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/RING/U-box	1.70e-06	27.9	2	68
E3 activity/RING/RING	9.20e-09	35.6	6	48

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 activity/RING/U-box

   S: 4    eeflCpIslelMrdPvvlpsGitydrssIekwlasggk...tcPvtrqplteedlvPnltlrrliqa 67
           e+ +C+I le ++dPv++ +G+ + r ++  + + +      cP +r+p ++e ++  + lr+l+++
   Q: 2    EDIMCSICLETFEDPVTIDCGHNFCRGCLSAHWSGYSYhgyLCPECRHPCSPERMKSDIRLRSLVEK 68
           5779****************************9655556689********************99876 PP

E3 activity/RING/RING

   S: 1    CaiCledfkdgplvlpCgHvfhadCl.qkwpglknssskefrCPlCr 46
           C+iCle f+d p++ +CgH f++ Cl  +w   +  s+   +CP Cr
   Q: 6    CSICLETFED-PVTIDCGHNFCRGCLsAHW-SGY--SYHGYLCPECR 48
           **********.999************9999.555..99999*****8 PP

Organism

Anolis carolinensis

Protein Sequence
(Fasta)

KEDIMCSICL ETFEDPVTID CGHNFCRGCL SAHWSGYSYH GYLCPECRHP CSPERMKSDI 60
RLRSLVEKIG QMPLLKLPES LSQTSVIQLK QPVQLVGLDE NGDICLDGEA LSHCLEQEQV 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

AAGGAAGATA TCATGTGTTC CATCTGCTTG GAAACCTTTG AAGACCCTGT TACCATTGAC 60
TGTGGACACA ATTTCTGCAG AGGATGTTTG TCTGCTCACT GGAGTGGATA CTCTTACCAC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0472--Membrane
KW-1185--Reference proteome
KW-0812--Transmembrane
KW-1133--Transmembrane helix

Interpro

IPR030386--G_GB1_RHD3_dom
IPR015894--Guanylate-bd_N
IPR027417--P-loop_NTPase
IPR001841--Znf_RING
IPR013083--Znf_RING/FYVE/PHD
IPR017907--Znf_RING_CS

PROSITE

PS51715--G_GB1_RHD3
PS00518--ZF_RING_1
PS50089--ZF_RING_2

Pfam

PF02263--GBP

SMART

SM00184--RING

Gene Ontology

GO:0005737--C:cytoplasm
GO:0016021--C:integral component of membrane
GO:0005634--C:nucleus
GO:0005525--F:GTP binding
GO:0003924--F:GTPase activity
GO:0008270--F:zinc ion binding
GO:0071158--P:positive regulation of cell cycle arrest
GO:0045687--P:positive regulation of glial cell differentiation
GO:0045666--P:positive regulation of neuron differentiation

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Lch-049938	Latimeria chalumnae	41.47	2.00e-89	322.00
IUUC-Meu-056771	Macropus eugenii	38.00	1.00e-101	363.00
IUUC-Mdo-062283	Monodelphis domestica	40.64	2.00e-103	369.00
IUUC-Oan-073272	Ornithorhynchus anatinus	37.62	4.00e-95	342.00
IUUC-Sha-107384	Sarcophilus harrisii	40.04	2.00e-103	369.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence