iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Sha-107495

UUCD1 version

Ensembl Protein ID

UniProt Accession

Genbank Protein ID

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AEFK01153799

Gene Name

USP1

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSSHAG00000018473.1	ENSSHAT00000021994.1	ENSSHAP00000021819.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
DUB/USP	5.20e-72	243.0	11	648

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

DUB/USP

   S: 46   kgellkslqklfeel.......w.....kskkkavsprellkalkkeaeefsgyeqqDaqEflaflldqleeelkk............. 109
           + el++slq+l+ ++       +     ++++ a++pr+ll++l++++++++gy q+DaqE+l+++l +++e+++              
   Q: 11   SYELICSLQSLIISVeqlqanfLlnpekYTDELATQPRRLLNTLRELNPMYEGYLQHDAQEVLQCILGNIQETCQLlkkeelknapggr 99
           458899999999888555555414455588888*****************************************556667788888886 PP
   S: 110  ........eknkpkeeeeeedkselsde............................................................. 129
                   ++  +++++++        +                                                             
   Q: 100  lpppqpeeREGRETHTMQD--------Ddseegkdkfpkgnvkrksdndagnpkkksklskelvateenqrqtrskrkaagdsrlegsp 180
           6544444322222222222........2556666679**************************************************** PP
   S: 130  ......................................................................................... 129
                                                                                                    
   Q: 181  eavpkgtadgdgarpshkksrlklnwlkptskqpsilskfcslgkitthlgpkgpsketdsdheedlkgeprgalkedpeeaappgtsm 269
           ***************************************************************************************99 PP
   S: 130  ........aeekkkkknkslisdlFqgqlksqikclecdnvssreepfldlslpvpgkeetkke..............slqdcLesftk 196
                   +++  ++   +l+++lFqgql  +++clec++ ++r+e+f+d+s+pv+++e +k +              sl++++++f++
   Q: 270  edkegqslRNKGMEQVCFELVEKLFQGQLVLRTRCLECESLTERREDFQDISVPVQEEEFSKVQesseispepktelkSLKWAISQFAS 358
           9876665544445555559***************************************98888899*********************** PP
   S: 197  eeelegenkyycekckkkqeaekklklkklPevLilhLkRf.....sfseeqksrekinkkvefpleLdlspfctspeekqkekkkYeL 280
            e++ ge+ky+ce+c++++eae++l ++k+Pev+++hLk+f     +f+++++  +kin+ + +pl+L+l+++ t+p+     +++Y L
   Q: 359  VERIVGEDKYFCENCHHYTEAERSLLFDKMPEVITIHLKCFaatglEFDCYGGGLSKINTPLLTPLKLSLEEWSTKPT-----NDSYGL 442
           ****************************************************************************99.....678*** PP
   S: 281  iavvvHsG.slssGHYvayvkn................................................................... 301
           +avv+HsG ++ssGHY+a vk                                                                    
   Q: 443  FAVVMHSGiTISSGHYTASVKVtdlnsleldtenfvvdqmyemakadplneedakalaeeyddevafrvnggaqpskvlskknvegvgl 531
           ***************************************************************************************** PP
   S: 302  ...........................................................................ekgkWllfdDskVt 315
                                                                                       +gkWllfdDs+V+
   Q: 532  lggqksrpdyefcsghrasgadkvigalaenrsaeasgtsgaqeldrtkepggpadlgangleskvsdviqslkeYEGKWLLFDDSEVK 620
           ******************************************9999999999999999999999888888887766999********** PP
   S: 316  evkeeevleetg......staYvlfYkr 337
           +++e+++l++ +      st+Y+lfYk+
   Q: 621  VTEEKDFLNSLSpatsstSTPYLLFYKK 648
           *********888**************97 PP

Organism

Sarcophilus harrisii

Protein Sequence
(Fasta)

QGNCKEDNLA SYELICSLQS LIISVEQLQA NFLLNPEKYT DELATQPRRL LNTLRELNPM 60
YEGYLQHDAQ EVLQCILGNI QETCQLLKKE ELKNAPGGRL PPPQPEEREG RETHTMQDDD 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CAGGGAAACT GCAAAGAGGA CAACCTGGCC AGCTACGAGC TCATCTGCAG CCTGCAGTCT 60
CTGATCATCT CCGTGGAGCA ACTTCAGGCC AATTTTCTTC TGAATCCAGA GAAATACACA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR001394--Peptidase_C19_UCH
IPR033815--USP1
IPR018200--USP_CS
IPR028889--USP_dom

PROSITE

PS00973--USP_2
PS50235--USP_3

Pfam

PF00443--UCH

Gene Ontology

GO:0005654--C:nucleoplasm
GO:0004197--F:cysteine-type endopeptidase activity
GO:0004843--F:thiol-dependent ubiquitin-specific protease activity
GO:0035520--P:monoubiquitinated protein deubiquitination
GO:0006282--P:regulation of DNA repair
GO:0009411--P:response to UV
GO:0001501--P:skeletal system development
GO:0006511--P:ubiquitin-dependent protein catabolic process

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001939	Ailuropoda melanoleuca	72.45	0.00e+00	877.00
IUUC-Apl-004204	Anas platyrhynchos	68.72	0.00e+00	783.00
IUUC-Aca-004637	Anolis carolinensis	64.09	0.00e+00	729.00
IUUC-Ame-011718	Astyanax mexicanus	47.46	5.00e-143	501.00
IUUC-Bta-012552	Bos taurus	71.34	0.00e+00	865.00
IUUC-Cja-019588	Callithrix jacchus	73.14	0.00e+00	884.00
IUUC-Cfa-020211	Canis familiaris	72.49	0.00e+00	875.00
IUUC-Cpo-021551	Cavia porcellus	69.72	0.00e+00	842.00
IUUC-Csa-024186	Chlorocebus sabaeus	72.74	0.00e+00	886.00
IUUC-Cho-024739	Choloepus hoffmanni	67.47	4.00e-113	401.00
IUUC-Dre-028184	Danio rerio	48.45	1.00e-147	516.00
IUUC-Dno-029669	Dasypus novemcinctus	71.71	0.00e+00	872.00
IUUC-Dor-030168	Dipodomys ordii	67.63	0.00e+00	740.00
IUUC-Dme-031732	Drosophila melanogaster	29.25	2.00e-19	91.30
IUUC-Ete-032825	Echinops telfairi	67.29	0.00e+00	704.00
IUUC-Eca-033595	Equus caballus	72.34	0.00e+00	875.00
IUUC-Eeu-034877	Erinaceus europaeus	70.33	1.00e-86	313.00
IUUC-Fca-035381	Felis catus	72.09	2.00e-158	551.00
IUUC-Fal-037592	Ficedula albicollis	66.72	0.00e+00	737.00
IUUC-Gmo-039680	Gadus morhua	45.25	4.00e-135	475.00
IUUC-Gga-041196	Gallus gallus	68.27	0.00e+00	793.00
IUUC-Gac-042292	Gasterosteus aculeatus	51.46	3.00e-111	395.00
IUUC-Ggo-044671	Gorilla gorilla	72.89	0.00e+00	887.00
IUUC-Hsa-047020	Homo sapiens	73.15	0.00e+00	885.00
IUUC-Itr-048800	Ictidomys tridecemlineatus	70.68	0.00e+00	834.00
IUUC-Lch-050543	Latimeria chalumnae	55.98	3.00e-171	595.00
IUUC-Loc-052338	Lepisosteus oculatus	50.88	2.00e-162	566.00
IUUC-Laf-053707	Loxodonta africana	71.66	0.00e+00	860.00
IUUC-Mcc-055885	Macaca mulatta	72.74	0.00e+00	888.00
IUUC-Meu-056573	Macropus eugenii	84.75	0.00e+00	1019.00
IUUC-Mga-059346	Meleagris gallopavo	69.17	0.00e+00	808.00
IUUC-Mmr-061612	Microcebus murinus	72.26	0.00e+00	858.00
IUUC-Mdo-062887	Monodelphis domestica	82.87	0.00e+00	976.00
IUUC-Mmu-064044	Mus musculus	72.58	0.00e+00	883.00
IUUC-Mpu-066847	Mustela putorius furo	72.45	0.00e+00	880.00
IUUC-Mlu-067684	Myotis lucifugus	71.93	0.00e+00	869.00
IUUC-Nle-070057	Nomascus leucogenys	72.78	0.00e+00	888.00
IUUC-Opr-070463	Ochotona princeps	69.95	0.00e+00	745.00
IUUC-Ont-071975	Oreochromis niloticus	51.11	5.00e-115	408.00
IUUC-Ocu-074840	Oryctolagus cuniculus	72.25	0.00e+00	863.00
IUUC-Ola-087088	Oryzias latipes	46.94	2.00e-138	486.00
IUUC-Oga-088472	Otolemur garnettii	71.78	0.00e+00	862.00
IUUC-Oar-089498	Ovis aries	72.15	0.00e+00	880.00
IUUC-Ptr-091395	Pan troglodytes	72.89	0.00e+00	886.00
IUUC-Pan-092462	Papio anubis	72.74	0.00e+00	888.00
IUUC-Psi-093583	Pelodiscus sinensis	68.55	0.00e+00	845.00
IUUC-Pfo-096314	Poecilia formosa	44.86	2.00e-128	453.00
IUUC-Pab-098568	Pongo abelii	72.74	0.00e+00	885.00
IUUC-Pca-100948	Procavia capensis	76.28	4.00e-129	455.00
IUUC-Pva-102853	Pteropus vampyrus	72.37	0.00e+00	877.00
IUUC-Rno-105573	Rattus norvegicus	72.34	0.00e+00	882.00
IUUC-Sar-113545	Sorex araneus	58.65	0.00e+00	645.00
IUUC-Ssc-115962	Sus scrofa	73.10	0.00e+00	885.00
IUUC-Tgu-116731	Taeniopygia guttata	68.84	0.00e+00	764.00
IUUC-Tru-117893	Takifugu rubripes	46.83	3.00e-126	445.00
IUUC-Tsy-119644	Tarsius syrichta	79.81	9.00e-138	484.00
IUUC-Tni-119819	Tetraodon nigroviridis	45.01	2.00e-134	473.00
IUUC-Tbe-127272	Tupaia belangeri	67.72	0.00e+00	796.00
IUUC-Ttr-128404	Tursiops truncatus	71.30	0.00e+00	863.00
IUUC-Vpa-130205	Vicugna pacos	72.62	0.00e+00	887.00
IUUC-Xtr-132613	Xenopus tropicalis	54.37	2.00e-171	595.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence