iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Nle-069477

Ensembl Protein ID

ENSNLEP00000021827.1

UniProt Accession

G1S8I8; G1S8I8_NOMLE

Genbank Protein ID

ENSNLEP00000021827

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

ADFV01003704

Gene Name

KIF21A

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSNLEG00000017964.2	ENSNLET00000022928.2	ENSNLEP00000021827.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	1.00e-29	101.3	1345	1379
UBD/Beta-Prp	5.00e-44	150.6	1450	1662

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 1    gHtdsvtclafsdtllvsGsdDgtikvWDlrtgvl 35
           gHt  v c++ +d+ll +Gs D t+kvW+l tg  
   Q: 1345 GHTKAVLCVDSTDDLLFTGSKDRTCKVWNLVTGQE 1379
           899*****99767*****************99976 PP

UBD/Beta-Prp

   S: 51   heaevtavkfspdgkilvtgseDrtikvwdlstgkcvhtlkghedsvlslsfsp..sg.dklvsGshdrtirvwdletgqclee... 131
            e++++++ ++p+g +++ +++ ++++ wdl+ ++ + +l+gh   v++l++++  +g d +++Gs+d +i+++d+ +g        
   Q: 1450 GENQINQIALNPTG-TFLYAASGNAVRMWDLKRFQSTGKLTGHLGPVMCLTVDQisNGqDLIITGSKDHYIKMFDVTEGALGTVspt 1535
           4668*********9.999*************************************9888*****************99987654677 PP
   S: 132  ..tlsghdgvvncvvvhpdgnllvsGslDrtvrlWdlktgkllrtltgghtdsvyslsfdsngkelvsgsldgtvklwdlqtgecvr 216
             ++ +h + +  +++++  + l+sGs D+ ++ Wdl +++ll++   +h+d v  l + ++ + l+sg + g +k+w++ t   v 
   Q: 1536 hnFEPPHYDGIEALTIQG--DNLFSGSRDNGIKKWDLTQKDLLQQVPNAHKDWVCALGVVPDHPVLLSGCRGGILKVWNMDTFMPVG 1620
           889999999999999999..7799**********************999************************************** PP
   S: 217  tlnghtdnvksvrfspnderlvsgssDgsiriW...dlrsgdll 257
           +++gh+++++ + +   ++++ ++++D+++riW   +l+ g++ 
   Q: 1621 EMKGHDSPINAICVN--STHIFTAADDRTVRIWkarNLQDGQIS 1662
           **********99888..****************99999988876 PP

Organism

Nomascus leucogenys

Protein Sequence
(Fasta)

MLGAPDESSV RVAVRIRPQL AKEKIEGCHI CTSVTPGEPQ VFLGKDKAFT FDYVFDIDSQ 60
QEQIYIQCIE KLIEGCFEGY NATVFAYGQT GAGKTYTMGT GFDVNIVEEE QGIISRAVKH 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CCCCATTTCT ACTGCGCCCG AGTCCCGCGG CCCCGGCGGC GCCTCAGCTC TGCGGTGCCG 60
AGGCCCAACG GCCCGGTCGC TGCCCGCTGC CAGCATGTTG GGCGCCCCGG ACGAGAGCTC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0067--ATP-binding
KW-0175--Coiled coil
KW-0181--Complete proteome
KW-0505--Motor protein
KW-0547--Nucleotide-binding
KW-1185--Reference proteome
KW-0853--WD repeat

Interpro

IPR019821--Kinesin_motor_CS
IPR001752--Kinesin_motor_dom
IPR027417--P-loop_NTPase
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS00411--KINESIN_MOTOR_1
PS50067--KINESIN_MOTOR_2
PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF00225--Kinesin
PF00400--WD40

PRINTS

PR00380--KINESINHEAVY

SMART

SM00129--KISc
SM00320--WD40

Gene Ontology

GO:0005524--F:ATP binding
GO:0003777--F:microtubule motor activity
GO:0007018--P:microtubule-based movement

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001391	Ailuropoda melanoleuca	96.36	0.00e+00	3078.00
IUUC-Apl-003353	Anas platyrhynchos	84.77	0.00e+00	2657.00
IUUC-Aca-004467	Anolis carolinensis	84.38	0.00e+00	2746.00
IUUC-Bta-013485	Bos taurus	95.38	0.00e+00	2969.00
IUUC-Cel-018402	Caenorhabditis elegans	53.10	8.00e-149	521.00
IUUC-Cja-019385	Callithrix jacchus	95.08	0.00e+00	3028.00
IUUC-Cfa-020986	Canis familiaris	96.16	0.00e+00	3007.00
IUUC-Cpo-022297	Cavia porcellus	92.42	0.00e+00	2888.00
IUUC-Csa-023685	Chlorocebus sabaeus	97.73	0.00e+00	3099.00
IUUC-Cho-024531	Choloepus hoffmanni	92.87	0.00e+00	1097.00
IUUC-Cin-025160	Ciona intestinalis	47.66	2.00e-88	320.00
IUUC-Csv-026158	Ciona savignyi	57.81	1.00e-177	617.00
IUUC-Dre-028532	Danio rerio	67.61	0.00e+00	2129.00
IUUC-Dno-029972	Dasypus novemcinctus	91.78	0.00e+00	2800.00
IUUC-Ete-032872	Echinops telfairi	80.20	0.00e+00	1043.00
IUUC-Eca-033518	Equus caballus	96.21	0.00e+00	3036.00
IUUC-Fca-036197	Felis catus	95.81	0.00e+00	3005.00
IUUC-Fal-037534	Ficedula albicollis	84.62	0.00e+00	2683.00
IUUC-Gga-040687	Gallus gallus	83.95	0.00e+00	2628.00
IUUC-Gac-041626	Gasterosteus aculeatus	67.61	0.00e+00	2182.00
IUUC-Ggo-044457	Gorilla gorilla	99.10	0.00e+00	3092.00
IUUC-Hsa-046372	Homo sapiens	99.34	0.00e+00	3129.00
IUUC-Lch-049786	Latimeria chalumnae	59.71	0.00e+00	1883.00
IUUC-Loc-052689	Lepisosteus oculatus	74.57	0.00e+00	2370.00
IUUC-Laf-054018	Loxodonta africana	90.26	0.00e+00	2786.00
IUUC-Mcc-055558	Macaca mulatta	98.81	0.00e+00	3119.00
IUUC-Meu-056080	Macropus eugenii	88.43	0.00e+00	991.00
IUUC-Mga-059283	Meleagris gallopavo	83.67	0.00e+00	2596.00
IUUC-Mmr-060773	Microcebus murinus	94.92	0.00e+00	2953.00
IUUC-Mdo-062688	Monodelphis domestica	89.97	0.00e+00	2632.00
IUUC-Mmu-063997	Mus musculus	92.84	0.00e+00	2894.00
IUUC-Mpu-066354	Mustela putorius furo	94.69	0.00e+00	3012.00
IUUC-Mlu-067599	Myotis lucifugus	95.26	0.00e+00	2966.00
IUUC-Opr-070188	Ochotona princeps	81.09	0.00e+00	1801.00
IUUC-Ont-071938	Oreochromis niloticus	69.42	0.00e+00	2185.00
IUUC-Oan-073055	Ornithorhynchus anatinus	88.59	0.00e+00	2660.00
IUUC-Ocu-074302	Oryctolagus cuniculus	92.20	0.00e+00	2959.00
IUUC-Ola-087491	Oryzias latipes	63.71	0.00e+00	1876.00
IUUC-Oga-088799	Otolemur garnettii	95.08	0.00e+00	2714.00
IUUC-Oar-089629	Ovis aries	93.52	0.00e+00	2944.00
IUUC-Pan-092214	Papio anubis	97.19	0.00e+00	3086.00
IUUC-Psi-093757	Pelodiscus sinensis	81.78	0.00e+00	2534.00
IUUC-Pfo-097448	Poecilia formosa	62.07	0.00e+00	1912.00
IUUC-Pab-097984	Pongo abelii	99.16	0.00e+00	3090.00
IUUC-Pca-101061	Procavia capensis	79.42	0.00e+00	1463.00
IUUC-Pva-102306	Pteropus vampyrus	94.03	0.00e+00	2916.00
IUUC-Rno-105354	Rattus norvegicus	91.34	0.00e+00	2820.00
IUUC-Sha-106938	Sarcophilus harrisii	89.38	0.00e+00	1820.00
IUUC-Ssc-115810	Sus scrofa	95.35	0.00e+00	2976.00
IUUC-Tgu-117076	Taeniopygia guttata	82.54	0.00e+00	2551.00
IUUC-Tru-117904	Takifugu rubripes	62.94	0.00e+00	1970.00
IUUC-Tsy-119020	Tarsius syrichta	95.06	0.00e+00	3000.00
IUUC-Tni-120813	Tetraodon nigroviridis	66.55	0.00e+00	2123.00
IUUC-Tbe-127494	Tupaia belangeri	82.67	0.00e+00	1046.00
IUUC-Ttr-128393	Tursiops truncatus	87.99	0.00e+00	2748.00
IUUC-Vpa-130675	Vicugna pacos	82.47	0.00e+00	778.00
IUUC-Xtr-132829	Xenopus tropicalis	78.41	0.00e+00	2538.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence