iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Nle-069812

UUCD1 version

Ensembl Protein ID

UniProt Accession

Genbank Protein ID

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

ADFV01076952

Gene Name

RBCK1

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSNLEG00000009499.1	ENSNLET00000012146.1	ENSNLEP00000011573.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
UBD/ZnF/NZF	2.80e-11	42.7	195	221
ULD/UDP/UBQ/UBQ_Other	7.40e-07	28.9	60	122

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

UBD/ZnF/NZF

   S: 3    aqWaCsaCTflNePeavkCemCsrpRg 29
            +W+C+ CTf+N+P +++CemC+r R+
   Q: 195  VGWQCPGCTFINKPTRPGCEMCCRARP 221
           68************************8 PP

ULD/UDP/UBQ/UBQ_Other

   S: 4    tvksldgseltlk..vnpsdtVaeLKekiekklgippeqqrLiykGkiL.eddktLadyglkdg 64
            v++++  + t++  v p++tVa LK++++   g+pp  q++++ G+ L +d  tL ++g++++
   Q: 60   SVEDAQMHTVTIWltVRPDMTVASLKDMVFLDYGFPPVLQQWVI-GQRLaRDQETLHSHGVRQN 122
           5666665577777889****************************.55555**********9875 PP

Organism

Nomascus leucogenys

Protein Sequence
(Fasta)

MDEKTKKAEE MALSLTRAVA GGDEQVARKC AIWLAEQRVP LSVQLKPEVS STQDIRLWVS 60
VEDAQMHTVT IWLTVRPDMT VASLKDMVFL DYGFPPVLQQ WVIGQRLARD QETLHSHGVR 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CCGGATGAGG CGACAATTTT TCCGGCCCCC TCCCAGTCCC GCCCCACTTC CGGGGCCGCC 60
ACTTTCACTT TCTCTTCCGC CGAAGCCGCT CCCCTTGCGA AGAACTGAGG CCTCCCGGGA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-0479--Metal-binding
KW-1185--Reference proteome
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR016150--Casein_kin_II_reg-sub_b-sht
IPR002867--IBR_dom
IPR029071--Ubiquitin-rel_dom
IPR000626--Ubiquitin_dom
IPR027370--Znf-RING_LisH
IPR001876--Znf_RanBP2
IPR001841--Znf_RING
IPR013083--Znf_RING/FYVE/PHD
IPR017907--Znf_RING_CS

PROSITE

PS50053--UBIQUITIN_2
PS01358--ZF_RANBP2_1
PS50199--ZF_RANBP2_2
PS00518--ZF_RING_1
PS50089--ZF_RING_2

Pfam

PF01485--IBR
PF13445--zf-RING_UBOX

SMART

SM00184--RING
SM00547--ZnF_RBZ

Gene Ontology

GO:0071797--C:LUBAC complex
GO:0004842--F:ubiquitin-protein transferase activity
GO:0008270--F:zinc ion binding
GO:0032088--P:negative regulation of NF-kappaB transcription factor activity
GO:0043123--P:positive regulation of I-kappaB kinase/NF-kappaB signaling
GO:0051092--P:positive regulation of NF-kappaB transcription factor activity
GO:0043161--P:proteasome-mediated ubiquitin-dependent protein catabolic process
GO:0097039--P:protein linear polyubiquitination
GO:0050852--P:T cell receptor signaling pathway

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001540	Ailuropoda melanoleuca	91.96	0.00e+00	851.00
IUUC-Apl-003627	Anas platyrhynchos	60.26	5.00e-18	81.60
IUUC-Aca-004507	Anolis carolinensis	64.32	3.00e-153	535.00
IUUC-Ame-011008	Astyanax mexicanus	52.95	2.00e-142	499.00
IUUC-Bta-013247	Bos taurus	94.31	0.00e+00	902.00
IUUC-Bci-013637	Botrytis cinerea	25.85	1.00e-12	68.90
IUUC-Cja-018880	Callithrix jacchus	97.45	0.00e+00	929.00
IUUC-Cfa-020477	Canis familiaris	94.12	0.00e+00	899.00
IUUC-Cpo-021558	Cavia porcellus	89.80	0.00e+00	848.00
IUUC-Csa-024129	Chlorocebus sabaeus	98.04	0.00e+00	892.00
IUUC-Cin-025630	Ciona intestinalis	39.67	3.00e-80	292.00
IUUC-Csv-026069	Ciona savignyi	51.20	4.00e-71	261.00
IUUC-Dre-027591	Danio rerio	52.92	1.00e-141	496.00
IUUC-Dno-029015	Dasypus novemcinctus	91.57	0.00e+00	858.00
IUUC-Dor-030313	Dipodomys ordii	82.27	0.00e+00	733.00
IUUC-Ete-032908	Echinops telfairi	80.60	0.00e+00	749.00
IUUC-Eca-034295	Equus caballus	76.94	0.00e+00	715.00
IUUC-Eeu-034454	Erinaceus europaeus	86.10	3.00e-114	405.00
IUUC-Fca-036380	Felis catus	94.71	0.00e+00	902.00
IUUC-Fal-037440	Ficedula albicollis	56.90	2.00e-15	72.80
IUUC-Gmo-038561	Gadus morhua	53.62	4.00e-119	421.00
IUUC-Gga-040198	Gallus gallus	38.12	3.00e-29	122.00
IUUC-Gac-041319	Gasterosteus aculeatus	52.54	1.00e-136	479.00
IUUC-Ggo-044456	Gorilla gorilla	67.88	8.00e-157	546.00
IUUC-Hsa-045738	Homo sapiens	99.22	0.00e+00	893.00
IUUC-Itr-049042	Ictidomys tridecemlineatus	92.35	0.00e+00	858.00
IUUC-Lch-050269	Latimeria chalumnae	44.74	9.00e-113	400.00
IUUC-Loc-052776	Lepisosteus oculatus	48.82	6.00e-132	464.00
IUUC-Laf-054269	Loxodonta africana	91.18	0.00e+00	874.00
IUUC-Mcc-055669	Macaca mulatta	98.82	0.00e+00	906.00
IUUC-Mga-059615	Meleagris gallopavo	54.69	1.00e-17	80.50
IUUC-Mmr-061562	Microcebus murinus	93.38	0.00e+00	771.00
IUUC-Mdo-062263	Monodelphis domestica	77.71	0.00e+00	741.00
IUUC-Mmu-064325	Mus musculus	90.78	0.00e+00	838.00
IUUC-Mpu-066385	Mustela putorius furo	94.12	0.00e+00	897.00
IUUC-Mlu-067000	Myotis lucifugus	90.59	0.00e+00	850.00
IUUC-Opr-070575	Ochotona princeps	93.63	7.00e-107	380.00
IUUC-Ont-072405	Oreochromis niloticus	50.59	8.00e-136	476.00
IUUC-Ocu-074358	Oryctolagus cuniculus	80.23	0.00e+00	760.00
IUUC-Ola-086403	Oryzias latipes	53.64	5.00e-138	484.00
IUUC-Oga-087986	Otolemur garnettii	93.14	0.00e+00	847.00
IUUC-Oar-089600	Ovis aries	91.76	0.00e+00	892.00
IUUC-Ptr-091224	Pan troglodytes	99.02	0.00e+00	892.00
IUUC-Pan-092739	Papio anubis	99.02	0.00e+00	909.00
IUUC-Pma-094407	Petromyzon marinus	57.91	4.00e-102	365.00
IUUC-Pfo-097161	Poecilia formosa	52.68	5.00e-132	464.00
IUUC-Pab-098627	Pongo abelii	99.02	0.00e+00	887.00
IUUC-Pca-100641	Procavia capensis	91.40	0.00e+00	810.00
IUUC-Pva-102670	Pteropus vampyrus	91.76	0.00e+00	860.00
IUUC-Pte-104234	Pyrenophora teres	25.41	3.00e-12	66.20
IUUC-Rno-105504	Rattus norvegicus	90.59	0.00e+00	834.00
IUUC-Sha-107342	Sarcophilus harrisii	77.13	0.00e+00	757.00
IUUC-Sar-113425	Sorex araneus	87.67	2.00e-111	395.00
IUUC-Ssc-115904	Sus scrofa	93.64	7.00e-90	322.00
IUUC-Tru-118096	Takifugu rubripes	51.73	8.00e-138	483.00
IUUC-Tni-119873	Tetraodon nigroviridis	49.51	6.00e-136	477.00
IUUC-Tbe-127578	Tupaia belangeri	90.78	0.00e+00	691.00
IUUC-Ttr-129107	Tursiops truncatus	93.92	0.00e+00	850.00
IUUC-Vpa-130353	Vicugna pacos	94.74	1.00e-122	432.00
IUUC-Xtr-132168	Xenopus tropicalis	42.41	6.00e-94	337.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence