iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Ggo-045035

Ensembl Protein ID

ENSGGOP00000009773.2

UniProt Accession

G3R3E7; G3R3E7_GORGO

Protein Name

Coronin

Gene Name

CORO1B

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSGGOG00000010013.2	ENSGGOT00000010052.2	ENSGGOP00000009773.2

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	1.00e-16	60.8	80	112

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 1    gHtdsvtclaf...sdtllvsGsdDgtikvWDl 30
           gHt++v ++++   +d  ++sGs D+t++vW +
   Q: 80   GHTGPVLDIDWcphNDEVIASGSEDCTVMVWQI 112
           8***********977799*************75 PP

Organism

Gorilla gorilla

Protein Sequence
(Fasta)

MSFRKVVRQS KFRHVFGQPV KNDQCYEDIR VSRVTWDSTF CAVNPKFLAV IVEASGGGAF 60
LVLPLSKTGR IDKAYPTVCG HTGPVLDIDW CPHNDEVIAS GSEDCTVMVW QIPENGLTSP 120

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Nucleotide Sequence
(Fasta)

CTCCGGGTCC CTCTGTCACT TCCTGAATCC TGCTTCCTGC TTCCCAGAGG CCGGGATCCG 60
GAGCCGCCCG AAGCCGGTGC CGCAGCCCCC TGCGCCCCCG GTGCCCCCGG TGAGCGCGGC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0677--Repeat
KW-0853--WD repeat

Interpro

IPR015505--Coronin
IPR015048--DUF1899
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF08953--DUF1899
PF00400--WD40

SMART

SM01166--DUF1899
SM00320--WD40

Gene Ontology

GO:0005884--C:actin filament
GO:0005829--C:cytosol
GO:0070062--C:extracellular exosome
GO:0005925--C:focal adhesion
GO:0030027--C:lamellipodium
GO:0048471--C:perinuclear region of cytoplasm
GO:0005886--C:plasma membrane
GO:0001725--C:stress fiber
GO:0090135--P:actin filament branching
GO:0051017--P:actin filament bundle assembly
GO:0036120--P:cellular response to platelet-derived growth factor stimulus
GO:0035767--P:endothelial cell chemotaxis
GO:0034316--P:negative regulation of Arp2/3 complex-mediated actin nucleation
GO:0071672--P:negative regulation of smooth muscle cell chemotaxis
GO:2000394--P:positive regulation of lamellipodium morphogenesis
GO:1902463--P:protein localization to cell leading edge
GO:0031529--P:ruffle organization
GO:0042060--P:wound healing

KEGG

ggo:101134174

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002423	Ailuropoda melanoleuca	94.48	0.00e+00	947.00
IUUC-Aca-005056	Anolis carolinensis	81.02	0.00e+00	811.00
IUUC-Bta-012984	Bos taurus	92.40	0.00e+00	932.00
IUUC-Cja-019498	Callithrix jacchus	98.16	0.00e+00	956.00
IUUC-Cfa-020937	Canis familiaris	97.19	0.00e+00	871.00
IUUC-Cpo-021866	Cavia porcellus	89.37	0.00e+00	894.00
IUUC-Csa-023561	Chlorocebus sabaeus	97.96	0.00e+00	962.00
IUUC-Dno-029770	Dasypus novemcinctus	87.17	0.00e+00	870.00
IUUC-Dor-030989	Dipodomys ordii	91.62	0.00e+00	905.00
IUUC-Eca-033901	Equus caballus	94.68	0.00e+00	933.00
IUUC-Fca-036494	Felis catus	94.48	0.00e+00	915.00
IUUC-Fal-036737	Ficedula albicollis	82.65	0.00e+00	837.00
IUUC-Hsa-046154	Homo sapiens	99.39	0.00e+00	972.00
IUUC-Itr-048847	Ictidomys tridecemlineatus	93.25	0.00e+00	906.00
IUUC-Laf-054566	Loxodonta africana	92.43	0.00e+00	895.00
IUUC-Mcc-054879	Macaca mulatta	98.16	0.00e+00	963.00
IUUC-Mmr-060910	Microcebus murinus	92.84	0.00e+00	926.00
IUUC-Mmu-063455	Mus musculus	94.89	0.00e+00	940.00
IUUC-Mpu-066350	Mustela putorius furo	94.07	0.00e+00	926.00
IUUC-Mlu-067353	Myotis lucifugus	93.83	0.00e+00	929.00
IUUC-Nle-069161	Nomascus leucogenys	99.18	0.00e+00	964.00
IUUC-Opr-071106	Ochotona princeps	91.62	0.00e+00	901.00
IUUC-Oga-088805	Otolemur garnettii	93.87	0.00e+00	937.00
IUUC-Ptr-091484	Pan troglodytes	98.98	0.00e+00	969.00
IUUC-Pan-091843	Papio anubis	97.75	0.00e+00	955.00
IUUC-Pab-097835	Pongo abelii	99.39	0.00e+00	971.00
IUUC-Pca-100411	Procavia capensis	82.00	0.00e+00	793.00
IUUC-Pva-102659	Pteropus vampyrus	94.48	0.00e+00	936.00
IUUC-Rno-106070	Rattus norvegicus	93.46	0.00e+00	931.00
IUUC-Sha-106609	Sarcophilus harrisii	94.08	0.00e+00	715.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence