iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Sha-106609

Ensembl Protein ID

ENSSHAP00000003328.1

UniProt Accession

G3VJH3; G3VJH3_SARHA

Genbank Protein ID

ENSSHAP00000003328

Protein Name

Coronin

Genbank Nucleotide ID

AEFK01225870

Gene Name

CORO1B

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSSHAG00000002926.1	ENSSHAT00000003364.1	ENSSHAP00000003328.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	2.30e-16	59.4	84	116

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 1    gHtdsvtclaf...sdtllvsGsdDgtikvWDl 30
           gHt++v ++++   +d  ++sGs D+t++vW +
   Q: 84   GHTGPVLDIDWcphNDEVIASGSEDCTVMVWQI 116
           8***********977799*************75 PP

Organism

Sarcophilus harrisii

Protein Sequence
(Fasta)

AWEVMSFRKV VRHSKFRHVF GQPVKNDQCY EDIRVSRVTW DSTFCAVNPR FLAIIVEASG 60
GGAFMVLPLS KTGRIDKSYP TVCGHTGPVL DIDWCPHNDE VIASGSEDCT VMVWQIPENG 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GCGTGGGAAG CGCAGGCCCG GATTTAGGCC CTGGTTCTCC CACCTCGCCA TCTGGAGGCC 60
TCAGGCTGGT TCCTGTGTGG GGCCTCAGTT TCCCCGTCTG TAAAGTGAAG GGGCATCCCT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0677--Repeat
KW-0853--WD repeat

Interpro

IPR011042--6-blade_b-propeller_TolB-like
IPR015505--Coronin
IPR015048--DUF1899
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF08953--DUF1899
PF00400--WD40

SMART

SM01166--DUF1899
SM00320--WD40

Gene Ontology

GO:0005884--C:actin filament
GO:0005829--C:cytosol
GO:0070062--C:extracellular exosome
GO:0005925--C:focal adhesion
GO:0030027--C:lamellipodium
GO:0048471--C:perinuclear region of cytoplasm
GO:0005886--C:plasma membrane
GO:0001725--C:stress fiber
GO:0090135--P:actin filament branching
GO:0051017--P:actin filament bundle assembly
GO:0036120--P:cellular response to platelet-derived growth factor stimulus
GO:0035767--P:endothelial cell chemotaxis
GO:0034316--P:negative regulation of Arp2/3 complex-mediated actin nucleation
GO:0071672--P:negative regulation of smooth muscle cell chemotaxis
GO:2000394--P:positive regulation of lamellipodium morphogenesis
GO:1902463--P:protein localization to cell leading edge
GO:0031529--P:ruffle organization
GO:0042060--P:wound healing

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002423	Ailuropoda melanoleuca	94.08	0.00e+00	710.00
IUUC-Aca-005056	Anolis carolinensis	89.01	0.00e+00	662.00
IUUC-Bta-012984	Bos taurus	94.05	0.00e+00	712.00
IUUC-Cja-019498	Callithrix jacchus	93.52	0.00e+00	710.00
IUUC-Cfa-020937	Canis familiaris	95.21	0.00e+00	720.00
IUUC-Cpo-021866	Cavia porcellus	93.80	0.00e+00	713.00
IUUC-Csa-023561	Chlorocebus sabaeus	94.08	0.00e+00	717.00
IUUC-Dno-029770	Dasypus novemcinctus	88.80	0.00e+00	664.00
IUUC-Dor-030989	Dipodomys ordii	94.37	0.00e+00	712.00
IUUC-Eca-033901	Equus caballus	93.80	0.00e+00	707.00
IUUC-Fca-036494	Felis catus	94.08	0.00e+00	708.00
IUUC-Fal-036737	Ficedula albicollis	91.55	0.00e+00	693.00
IUUC-Ggo-045035	Gorilla gorilla	94.08	0.00e+00	715.00
IUUC-Hsa-046154	Homo sapiens	94.08	0.00e+00	715.00
IUUC-Itr-048847	Ictidomys tridecemlineatus	94.37	0.00e+00	715.00
IUUC-Laf-054566	Loxodonta africana	93.80	0.00e+00	707.00
IUUC-Mcc-054879	Macaca mulatta	93.52	0.00e+00	715.00
IUUC-Meu-056319	Macropus eugenii	98.26	2.00e-169	588.00
IUUC-Mmr-060910	Microcebus murinus	94.93	0.00e+00	721.00
IUUC-Mmu-063455	Mus musculus	94.37	0.00e+00	718.00
IUUC-Mpu-066350	Mustela putorius furo	95.21	0.00e+00	722.00
IUUC-Mlu-067353	Myotis lucifugus	94.65	0.00e+00	712.00
IUUC-Nle-069161	Nomascus leucogenys	94.08	0.00e+00	711.00
IUUC-Opr-071106	Ochotona princeps	93.52	0.00e+00	707.00
IUUC-Oga-088805	Otolemur garnettii	94.37	0.00e+00	717.00
IUUC-Oar-090373	Ovis aries	90.58	0.00e+00	691.00
IUUC-Ptr-091484	Pan troglodytes	94.08	0.00e+00	714.00
IUUC-Pan-091843	Papio anubis	93.24	0.00e+00	706.00
IUUC-Pab-097835	Pongo abelii	94.08	0.00e+00	715.00
IUUC-Pca-100411	Procavia capensis	93.24	0.00e+00	707.00
IUUC-Pva-102659	Pteropus vampyrus	94.08	0.00e+00	713.00
IUUC-Rno-106070	Rattus norvegicus	93.80	0.00e+00	714.00
IUUC-Ssc-115980	Sus scrofa	91.16	0.00e+00	694.00
IUUC-Tgu-117329	Taeniopygia guttata	91.55	0.00e+00	687.00
IUUC-Tbe-127679	Tupaia belangeri	72.52	9.00e-158	549.00
IUUC-Vpa-130339	Vicugna pacos	82.28	6.00e-175	606.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence