iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Ssc-115470

Ensembl Protein ID

ENSSSCP00000029802.1

UniProt Accession

K7GPI8; K7GPI8_PIG

Genbank Protein ID

ENSSSCP00000029802

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

CU207279

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSSSCG00000022479.2	ENSSSCT00000035758.1	ENSSSCP00000029802.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/HECT	1.30e-80	271.6	1262	1584

Active Site

Position(s)	Description	Evidence
1554	Glycyl thioester intermediate	{ECO:0000256\|PROSITE-ProRule:PRU00104}

Domain Profile

E3 activity/HECT

   S: 17   egldlgGvtreflallskelqnpd..lglf.lysendketlqpnpdsglknpehlklFeflGrllgkalqdgrlldlplsksfykll 100
           e+ + +G++r ++++ ++++ + d  ++lf +  +++ +t +p +++      +l++F+ +Gr+lg++l +++l++++l+++++k l
   Q: 1262 ENRKRHGSSRSVVDMDLDDTDDGDdnAPLFyQPGKRGFYTPRPGKNTE----ARLNCFRNIGRILGLCLLQNELCPITLNRHVIKVL 1344
           556778**************9999778888334444777777777775....89********************************* PP
   S: 101  lgkklsledleevdpelyks.lkeikena..esdieelgldltfsvseeilgetkeeeLkpgGenipVtneNkeeYvklvveyrlke 184
           lg+k++++d++ +dp +y+s  + i++++  ++d   +++dl+f ++ ++ +   ++eL+p+G nipVt +N +eYv++++e+r+  
   Q: 1345 LGRKVNWHDFAFFDPVMYESlRQLILASQssDADAVFSAMDLAFAIDLCKEEGGGQVELIPNGVNIPVTPQNVYEYVRKYAEHRMLV 1431
           ********************5556666655556888999************************************************ PP
   S: 185  gikeqveafreGfneviplellslFteeelellicGeeeidvedlkketkykggytedspai....qwFwevleefsseerkafLqF 267
             ++ ++a+r+G+ +v+p+++l+ +t+e+++ll++G+ e++v++l ++t+++++  e+ +++    +wFw+++e++s++er++++ F
   Q: 1432 VAEQPLHAMRKGLLDVLPKNSLEDLTAEDFRLLVNGCGEVNVQMLISFTSFNDESGENAEKLlqfkRWFWSIVEKMSMTERQDLVYF 1518
           ***************************************************9999999999989999******************** PP
   S: 268  vTgssrlPl..gGfaelkprlfvirkdasddrlPssnTCfnyLkLPeYsskeilkekLlyAieetkgFel 335
           +T+s++lP+  +Gf++++  +++ir   +d++lP++nTC+++L +P Yssk+ilk+kLl+Ai++ k+F++
   Q: 1519 WTSSPSLPAseEGFQPMP--SITIRP-PDDQHLPTANTCISRLYVPLYSSKQILKQKLLLAIKT-KNFGF 1584
           *********999******..799999.99**********************************9.99875 PP

Organism

Sus scrofa

Protein Sequence
(Fasta)

XFCTCILFRL KRTSPTAYCD CWEKCKCKTL IAGQKSARLD LLYRLLTATN LVTLPNSRGE 60
HLLLFLVQTV ARQTVEHCQY RPPRIREDRN RKTANPEDSD MPDHDLEPPR FAQLALERVL 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GTTTTTGTAC TTGTATTCTT TTTAGACTCA AACGGACATC ACCAACAGCC TATTGTGATT 60
GTTGGGAGAA ATGTAAATGT AAAACTCTAA TTGCTGGACA GAAATCTGCT CGTCTTGATC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0808--Transferase
KW-0833--Ubl conjugation pathway

Interpro

IPR000569--HECT_dom
IPR002004--PABP_HYD

PROSITE

PS50237--HECT
PS51309--PABC

Pfam

PF00632--HECT
PF00658--PABP

SMART

SM00119--HECTc
SM00517--PolyA

Gene Ontology

GO:0003723--F:RNA binding
GO:0004842--F:ubiquitin-protein transferase activity

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002217	Ailuropoda melanoleuca	99.87	0.00e+00	2560.00
IUUC-Apl-004165	Anas platyrhynchos	97.34	0.00e+00	2494.00
IUUC-Aca-004577	Anolis carolinensis	97.40	0.00e+00	2471.00
IUUC-Ame-010702	Astyanax mexicanus	86.36	0.00e+00	2263.00
IUUC-Bta-012313	Bos taurus	99.68	0.00e+00	2555.00
IUUC-Cel-018165	Caenorhabditis elegans	43.62	3.00e-67	251.00
IUUC-Cja-019858	Callithrix jacchus	99.30	0.00e+00	2568.00
IUUC-Cfa-020973	Canis familiaris	99.75	0.00e+00	2557.00
IUUC-Cpo-022065	Cavia porcellus	95.67	0.00e+00	1009.00
IUUC-Csa-023985	Chlorocebus sabaeus	99.49	0.00e+00	2575.00
IUUC-Cho-025034	Choloepus hoffmanni	89.54	0.00e+00	993.00
IUUC-Cin-025715	Ciona intestinalis	45.52	0.00e+00	796.00
IUUC-Csv-026131	Ciona savignyi	47.88	0.00e+00	687.00
IUUC-Dre-027730	Danio rerio	88.80	0.00e+00	2319.00
IUUC-Dno-029123	Dasypus novemcinctus	96.71	0.00e+00	2461.00
IUUC-Dor-030757	Dipodomys ordii	98.82	0.00e+00	994.00
IUUC-Dme-032192	Drosophila melanogaster	51.83	5.00e-174	606.00
IUUC-Ete-032292	Echinops telfairi	94.97	0.00e+00	1468.00
IUUC-Eca-034347	Equus caballus	99.49	0.00e+00	2546.00
IUUC-Eeu-034873	Erinaceus europaeus	92.14	0.00e+00	2343.00
IUUC-Fca-036485	Felis catus	99.22	0.00e+00	2460.00
IUUC-Fal-037071	Ficedula albicollis	98.48	0.00e+00	2504.00
IUUC-Gmo-039589	Gadus morhua	89.66	0.00e+00	2320.00
IUUC-Gga-041195	Gallus gallus	95.75	0.00e+00	2412.00
IUUC-Gac-042538	Gasterosteus aculeatus	89.28	0.00e+00	2340.00
IUUC-Ggo-045351	Gorilla gorilla	97.98	0.00e+00	2581.00
IUUC-Hsa-045941	Homo sapiens	99.37	0.00e+00	2571.00
IUUC-Itr-048635	Ictidomys tridecemlineatus	99.37	0.00e+00	2550.00
IUUC-Lch-050480	Latimeria chalumnae	95.88	0.00e+00	2454.00
IUUC-Loc-052664	Lepisosteus oculatus	90.85	0.00e+00	2386.00
IUUC-Laf-053960	Loxodonta africana	97.37	0.00e+00	1565.00
IUUC-Mcc-054703	Macaca mulatta	99.56	0.00e+00	2579.00
IUUC-Meu-056431	Macropus eugenii	87.46	0.00e+00	791.00
IUUC-Mga-059289	Meleagris gallopavo	98.23	0.00e+00	2553.00
IUUC-Mmr-061737	Microcebus murinus	99.49	0.00e+00	2552.00
IUUC-Mdo-062499	Monodelphis domestica	98.16	0.00e+00	2491.00
IUUC-Mmu-063273	Mus musculus	98.67	0.00e+00	2518.00
IUUC-Mpu-066907	Mustela putorius furo	99.87	0.00e+00	2558.00
IUUC-Mlu-067942	Myotis lucifugus	99.37	0.00e+00	2586.00
IUUC-Nle-069527	Nomascus leucogenys	99.37	0.00e+00	2573.00
IUUC-Opr-070626	Ochotona princeps	74.29	0.00e+00	767.00
IUUC-Ont-071951	Oreochromis niloticus	88.52	0.00e+00	2301.00
IUUC-Oan-072958	Ornithorhynchus anatinus	98.54	0.00e+00	2496.00
IUUC-Ocu-074503	Oryctolagus cuniculus	97.34	0.00e+00	2533.00
IUUC-Ola-086757	Oryzias latipes	89.10	0.00e+00	2319.00
IUUC-Oga-088781	Otolemur garnettii	99.24	0.00e+00	2544.00
IUUC-Oar-089274	Ovis aries	99.68	0.00e+00	2554.00
IUUC-Ptr-090669	Pan troglodytes	99.30	0.00e+00	2570.00
IUUC-Pan-092226	Papio anubis	99.11	0.00e+00	2552.00
IUUC-Psi-093502	Pelodiscus sinensis	98.16	0.00e+00	2499.00
IUUC-Pma-094454	Petromyzon marinus	85.57	2.00e-137	484.00
IUUC-Pfo-096173	Poecilia formosa	88.75	0.00e+00	2307.00
IUUC-Pab-098355	Pongo abelii	99.66	0.00e+00	1337.00
IUUC-Pca-100570	Procavia capensis	93.71	0.00e+00	832.00
IUUC-Pva-102572	Pteropus vampyrus	99.34	0.00e+00	872.00
IUUC-Rno-104916	Rattus norvegicus	98.42	0.00e+00	2511.00
IUUC-Sha-106653	Sarcophilus harrisii	98.54	0.00e+00	2504.00
IUUC-Sar-113517	Sorex araneus	98.48	0.00e+00	1131.00
IUUC-Tgu-116932	Taeniopygia guttata	98.10	0.00e+00	2489.00
IUUC-Tru-117682	Takifugu rubripes	88.25	0.00e+00	2295.00
IUUC-Tsy-119417	Tarsius syrichta	94.80	0.00e+00	2453.00
IUUC-Tni-120442	Tetraodon nigroviridis	82.43	0.00e+00	2060.00
IUUC-Tbe-127456	Tupaia belangeri	93.98	0.00e+00	838.00
IUUC-Ttr-128606	Tursiops truncatus	99.60	0.00e+00	860.00
IUUC-Vpa-130112	Vicugna pacos	95.47	0.00e+00	2373.00
IUUC-Xtr-131929	Xenopus tropicalis	94.24	0.00e+00	2495.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence