iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Mdo-061935

UUCD1 version

UUC-MoD-01129

Ensembl Protein ID

ENSMODP00000009619.3

UniProt Accession

F7BK86; F7BK86_MONDO

Protein Name

Uncharacterized protein

Gene Name

USP40

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSMODG00000007745.3	ENSMODT00000009810.3	ENSMODP00000009619.3

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
DUB/USP	5.60e-80	269.2	95	545

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

DUB/USP

   S: 1    tGlkNlgNtCYmNSvLQcLsnipelrelllekkkeklneenpkepkg....ellkslqklfeelwkskkkavsprellkalkkeaeefs 85
           +Gl+N+g tCY+NS+LQ+L+++pe+re+l+  ++e+l   ++k++       +  +lq+lf++l+ s+++a s+++l++++++ ++e  
   Q: 95   CGLQNQGGTCYLNSLLQTLHFTPEFREALFALDPEELGSLEDKDDPDakvrIIPLQLQRLFTQLLLSDQQAASTTDLTDSFGWSNSE-- 181
           7******************************889888776653333345558899******************************98.. PP
   S: 86   gyeqqDaqEflaflldqleeelkkeknkpkeeeeeedkselsdeaeekkkkknkslisdlFqgqlksqikclecdnvssreepfldlsl 174
           +++q+D+qE+ ++l+++le++l                            +++++li++l++g++ ++i+c ec+nvs+r+e+fldl++
   Q: 182  EMRQHDVQELNRILFSALESSL--------------------------VGTSGHDLIQQLYHGTVVNHIMCRECENVSERQEDFLDLTV 244
           **********************..........................789************************************** PP
   S: 175  pvpgkeetkkeslqdcL.esftkeeelegenkyycekckkkqeaekklklkklPevLilhLkRfsfseeqksrekinkkvefpleLdls 262
           +v++ +      l+++L +++++ee ++gen y+c  c+k++ a+k+ +l+klP++L++ L Rf+f+ +++ r k +  ++fpl++dl+
   Q: 245  AVKDLS-----GLEEALwSMYVEEEFFDGENLYHCGACNKLVSAVKSAQLRKLPPFLTISLLRFNFDFAKCERYKETGAYTFPLQMDLK 328
           ****99.....9*****999********************************************************************* PP
   S: 263  pfctspeekqkekkkYeLiavvvHsGslssGHYvayvkn.................................................. 301
           pfc+++e +++ ++ Y+L++v++H+G++ +GHY++y+k+                                                  
   Q: 329  PFCEQSELDDS-EYVYDLFSVIIHKGGCYGGHYHVYIKDvdqlgnwylevsrrkqrqevaqgeqisheptekldllkleeeenhlipvd 416
           *****998875.9**************************************************************************** PP
   S: 302  ......................................................................................... 301
                                                                                                    
   Q: 417  qlgqkllasieiswnkkfrkeygpllkflqahsdvfllssnpskvclreaspsqpspaelkqpspedpfqdqappsseaepagdpqlev 505
           ***********************************************************************999999999999998888 PP
   S: 302  ..ekgkWllfdDskVtevkeeevleetg..staYvlfYkr 337
             e  +W+ ++Ds+V++++e++++++ +  ++aY+lfY++
   Q: 506  riEGPQWFDLNDSQVEPIQEADIEKQFQgkESAYMLFYRK 545
           866777*******************9889*********98 PP

Organism

Monodelphis domestica

Protein Sequence
(Fasta)

MCDGSCSPRA GAWAAREATA PPHQDGGVPP RPPRSLPVGV AGPGGRALAP RAFRMFGDLF 60
EEDFPSISES RWERGRKSKA LHPEPSPPRG LTRLCGLQNQ GGTCYLNSLL QTLHFTPEFR 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGTGCGACG GGAGCTGTAG TCCGCGCGCA GGCGCATGGG CCGCCCGGGA GGCGACGGCG 60
CCCCCGCACC AAGATGGCGG CGTCCCGCCG CGCCCTCCTC GTTCTCTTCC CGTTGGGGTC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR001394--Peptidase_C19_UCH
IPR018200--USP_CS
IPR028889--USP_dom

PROSITE

PS00972--USP_1
PS00973--USP_2
PS50235--USP_3

Pfam

PF00443--UCH

Gene Ontology

GO:0036459--F:thiol-dependent ubiquitinyl hydrolase activity
GO:0016579--P:protein deubiquitination
GO:0006511--P:ubiquitin-dependent protein catabolic process

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001216	Ailuropoda melanoleuca	61.84	0.00e+00	1404.00
IUUC-Apl-004105	Anas platyrhynchos	59.84	0.00e+00	1444.00
IUUC-Aca-004715	Anolis carolinensis	57.24	0.00e+00	1355.00
IUUC-Ame-011073	Astyanax mexicanus	46.64	0.00e+00	1003.00
IUUC-Bta-012487	Bos taurus	63.78	0.00e+00	1471.00
IUUC-Cja-018937	Callithrix jacchus	62.53	0.00e+00	1474.00
IUUC-Cfa-020645	Canis familiaris	58.89	0.00e+00	877.00
IUUC-Cpo-022160	Cavia porcellus	60.68	0.00e+00	1428.00
IUUC-Csa-023078	Chlorocebus sabaeus	62.43	0.00e+00	1506.00
IUUC-Cho-025013	Choloepus hoffmanni	51.18	2.00e-169	590.00
IUUC-Csv-026193	Ciona savignyi	54.08	5.00e-58	217.00
IUUC-Dre-027416	Danio rerio	48.65	0.00e+00	1100.00
IUUC-Dno-029639	Dasypus novemcinctus	60.49	0.00e+00	1193.00
IUUC-Dor-030624	Dipodomys ordii	72.85	1.00e-120	427.00
IUUC-Ete-032626	Echinops telfairi	52.68	3.00e-174	605.00
IUUC-Eca-034208	Equus caballus	62.85	0.00e+00	1516.00
IUUC-Eeu-035340	Erinaceus europaeus	41.86	1.00e-63	238.00
IUUC-Fca-035886	Felis catus	59.12	2.00e-172	598.00
IUUC-Fal-036925	Ficedula albicollis	59.35	0.00e+00	1345.00
IUUC-Gmo-038597	Gadus morhua	44.49	0.00e+00	862.00
IUUC-Gga-041171	Gallus gallus	59.94	0.00e+00	1432.00
IUUC-Gac-041362	Gasterosteus aculeatus	44.77	0.00e+00	949.00
IUUC-Ggo-045069	Gorilla gorilla	60.87	0.00e+00	1347.00
IUUC-Hsa-046715	Homo sapiens	61.97	0.00e+00	1484.00
IUUC-Itr-049006	Ictidomys tridecemlineatus	60.40	0.00e+00	1387.00
IUUC-Lch-050182	Latimeria chalumnae	50.12	0.00e+00	1120.00
IUUC-Loc-052705	Lepisosteus oculatus	52.01	0.00e+00	1227.00
IUUC-Laf-054132	Loxodonta africana	62.89	0.00e+00	1524.00
IUUC-Mcc-055734	Macaca mulatta	62.28	0.00e+00	1507.00
IUUC-Meu-056135	Macropus eugenii	68.88	2.00e-132	467.00
IUUC-Mga-060092	Meleagris gallopavo	59.51	0.00e+00	1404.00
IUUC-Mmr-061546	Microcebus murinus	59.59	0.00e+00	1393.00
IUUC-Mmu-063630	Mus musculus	60.62	0.00e+00	1446.00
IUUC-Mpu-066579	Mustela putorius furo	60.50	0.00e+00	1498.00
IUUC-Mlu-068034	Myotis lucifugus	62.85	0.00e+00	1456.00
IUUC-Nle-069082	Nomascus leucogenys	59.05	0.00e+00	1179.00
IUUC-Opr-070953	Ochotona princeps	53.79	0.00e+00	702.00
IUUC-Ont-072435	Oreochromis niloticus	47.49	0.00e+00	1073.00
IUUC-Oan-073339	Ornithorhynchus anatinus	61.98	0.00e+00	1461.00
IUUC-Ocu-073760	Oryctolagus cuniculus	61.02	0.00e+00	1456.00
IUUC-Ola-087015	Oryzias latipes	45.29	0.00e+00	895.00
IUUC-Oga-088960	Otolemur garnettii	61.90	0.00e+00	1463.00
IUUC-Oar-089853	Ovis aries	64.16	0.00e+00	1496.00
IUUC-Ptr-091093	Pan troglodytes	61.97	0.00e+00	1485.00
IUUC-Pan-091962	Papio anubis	61.67	0.00e+00	1488.00
IUUC-Psi-093691	Pelodiscus sinensis	61.86	0.00e+00	1508.00
IUUC-Pma-094428	Petromyzon marinus	64.75	5.00e-92	330.00
IUUC-Pfo-096983	Poecilia formosa	46.62	0.00e+00	1000.00
IUUC-Pab-097860	Pongo abelii	61.43	0.00e+00	1367.00
IUUC-Pca-100514	Procavia capensis	51.93	8.00e-136	478.00
IUUC-Pva-102771	Pteropus vampyrus	61.36	0.00e+00	1367.00
IUUC-Rno-105405	Rattus norvegicus	60.10	0.00e+00	1423.00
IUUC-Sha-107376	Sarcophilus harrisii	78.68	0.00e+00	1837.00
IUUC-Ssc-115819	Sus scrofa	57.30	0.00e+00	969.00
IUUC-Tgu-117262	Taeniopygia guttata	58.93	0.00e+00	1401.00
IUUC-Tru-117601	Takifugu rubripes	46.55	0.00e+00	1065.00
IUUC-Tsy-118996	Tarsius syrichta	54.09	0.00e+00	812.00
IUUC-Tni-120682	Tetraodon nigroviridis	43.07	0.00e+00	843.00
IUUC-Tbe-127616	Tupaia belangeri	50.75	0.00e+00	651.00
IUUC-Ttr-129075	Tursiops truncatus	61.73	0.00e+00	1386.00
IUUC-Vpa-130108	Vicugna pacos	63.21	0.00e+00	1334.00
IUUC-Xtr-132623	Xenopus tropicalis	51.10	0.00e+00	1153.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence