iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Ggo-044608

Ensembl Protein ID

ENSGGOP00000005025.2

UniProt Accession

G3QQZ5; G3QQZ5_GORGO

Protein Name

Tyrosine-protein kinase

Gene Name

BLK

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSGGOG00000005127.2	ENSGGOT00000022100.1	ENSGGOP00000017853.1
ENSGGOG00000005127.2	ENSGGOT00000005154.2	ENSGGOP00000005025.2

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
UBD/SH3	4.30e-14	52.6	2	59

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

UBD/SH3

   S: 3    kekvqvlydyeaqnddeLtlkkGdvvlviekeeqdegWlkgvkelegkrGlfPenFvekle 63
           k+ v +lydy+a nd +L++ kG++++v+   +  ++W+ + +  +g++G +P+nFv+++e
   Q: 2    KHFVVALYDYTAMNDRDLQMLKGEKLQVL---KGTGDWWLARSLVTGREGYVPSNFVARVE 59
           67899************************...999************************97 PP

Organism

Gorilla gorilla

Protein Sequence
(Fasta)

DKHFVVALYD YTAMNDRDLQ MLKGEKLQVL KGTGDWWLAR SLVTGREGYV PSNFVARVES 60
LEMERWFFRS LGRKEAERQL LAPINKAGSF LIRESETNKG AFSLSVKDVT TQGELIKHYK 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CCCTTGTCCA TTTTAGACAA GCATTTCGTG GTGGCTCTGT ATGACTACAC CGCTATGAAT 60
GATCGGGACC TGCAGATGCT GAAGGGGGAG AAGCTACAGG TCCTGAAGGG GTGAGGTTCC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0067--ATP-binding
KW-0181--Complete proteome
KW-0418--Kinase
KW-0547--Nucleotide-binding
KW-1185--Reference proteome
KW-0728--SH3 domain
KW-0808--Transferase
KW-0829--Tyrosine-protein kinase

Interpro

IPR011009--Kinase-like_dom
IPR000719--Prot_kinase_dom
IPR017441--Protein_kinase_ATP_BS
IPR001245--Ser-Thr/Tyr_kinase_cat_dom
IPR000980--SH2
IPR001452--SH3_domain
IPR020635--Tyr_kinase_cat_dom

PROSITE

PS00107--PROTEIN_KINASE_ATP
PS50011--PROTEIN_KINASE_DOM
PS50001--SH2
PS50002--SH3

Pfam

PF07714--Pkinase_Tyr
PF00017--SH2
PF00018--SH3_1

PRINTS

PR00401--SH2DOMAIN
PR00452--SH3DOMAIN
PR00109--TYRKINASE

SMART

SM00252--SH2
SM00326--SH3
SM00219--TyrKc

Gene Ontology

GO:0005524--F:ATP binding
GO:0004715--F:non-membrane spanning protein tyrosine kinase activity
GO:0050853--P:B cell receptor signaling pathway
GO:0032024--P:positive regulation of insulin secretion

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002133	Ailuropoda melanoleuca	91.55	0.00e+00	832.00
IUUC-Apl-003307	Anas platyrhynchos	75.24	0.00e+00	697.00
IUUC-Aca-004357	Anolis carolinensis	68.94	0.00e+00	639.00
IUUC-Bta-012400	Bos taurus	90.61	0.00e+00	825.00
IUUC-Cja-019717	Callithrix jacchus	90.83	0.00e+00	654.00
IUUC-Cfa-021056	Canis familiaris	91.08	0.00e+00	826.00
IUUC-Cpo-021779	Cavia porcellus	89.20	0.00e+00	812.00
IUUC-Csa-023557	Chlorocebus sabaeus	96.95	0.00e+00	863.00
IUUC-Eca-034218	Equus caballus	90.85	0.00e+00	824.00
IUUC-Eeu-035095	Erinaceus europaeus	68.31	2.00e-170	592.00
IUUC-Fca-036015	Felis catus	90.38	0.00e+00	821.00
IUUC-Fal-036946	Ficedula albicollis	75.24	0.00e+00	694.00
IUUC-Gga-040822	Gallus gallus	74.47	0.00e+00	699.00
IUUC-Hsa-046719	Homo sapiens	98.59	0.00e+00	872.00
IUUC-Itr-048323	Ictidomys tridecemlineatus	92.20	0.00e+00	828.00
IUUC-Laf-053387	Loxodonta africana	88.97	0.00e+00	806.00
IUUC-Mcc-055026	Macaca mulatta	97.42	0.00e+00	864.00
IUUC-Mga-059427	Meleagris gallopavo	73.83	0.00e+00	689.00
IUUC-Mmr-061660	Microcebus murinus	91.73	0.00e+00	822.00
IUUC-Mdo-062318	Monodelphis domestica	77.00	0.00e+00	722.00
IUUC-Mmu-063325	Mus musculus	89.44	0.00e+00	811.00
IUUC-Mpu-066582	Mustela putorius furo	91.55	0.00e+00	830.00
IUUC-Nle-069624	Nomascus leucogenys	97.88	0.00e+00	868.00
IUUC-Opr-070656	Ochotona princeps	84.27	0.00e+00	750.00
IUUC-Ocu-073907	Oryctolagus cuniculus	88.73	0.00e+00	809.00
IUUC-Oga-088057	Otolemur garnettii	93.16	0.00e+00	841.00
IUUC-Oar-089332	Ovis aries	84.74	0.00e+00	761.00
IUUC-Ptr-091551	Pan troglodytes	97.37	0.00e+00	1012.00
IUUC-Pan-092173	Papio anubis	97.16	0.00e+00	859.00
IUUC-Psi-093895	Pelodiscus sinensis	74.71	0.00e+00	699.00
IUUC-Pab-097598	Pongo abelii	97.87	0.00e+00	859.00
IUUC-Pva-102135	Pteropus vampyrus	90.61	0.00e+00	822.00
IUUC-Rno-104891	Rattus norvegicus	90.14	0.00e+00	820.00
IUUC-Sha-107192	Sarcophilus harrisii	80.52	0.00e+00	744.00
IUUC-Ssc-115696	Sus scrofa	90.61	0.00e+00	822.00
IUUC-Tgu-117056	Taeniopygia guttata	74.47	0.00e+00	688.00
IUUC-Tbe-127520	Tupaia belangeri	89.82	0.00e+00	631.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence