iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Eca-034161

UUCD1 version

UUC-EqC-00318

Ensembl Protein ID

ENSECAP00000020181.1

UniProt Accession

F6V704; F6V704_HORSE

Protein Name

Uncharacterized protein

Gene Name

EML6

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSECAG00000022521.1	ENSECAT00000024300.1	ENSECAP00000020181.1
ENSECAG00000022521.1	ENSECAT00000024310.1	ENSECAP00000020189.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	7.00e-49	161.8	1630	1662
UBD/Beta-Prp	7.10e-121	403.1	660	878

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 4    dsvtclaf.sd.tllvsGsdDgtikvWDlrtgv 34
           +++++la  ++ ++++s+s+Dgt ++WDl + +
   Q: 1630 GEIWGLAThPSkDIFISASNDGTARIWDLADKK 1662
           4688888887779***************98765 PP

UBD/Beta-Prp

   S: 7    ghhksvitcvkfspdksllatg..srdgtikvwdvttgkllrsl.sgheaevtavkfspdgkilvtgseD..rtikvwdlstgkcvhtl 90
           gh+++ ++ ++++p k+++atg  +rd+ i vwd++t k+l+ l  +h+ +v a++fs dgk lv+++ D  + i  wd ++g+ + t 
   Q: 660  GHDDDILS-LTIHPVKDYVATGqvGRDAAIHVWDTQTLKCLSLLkGQHQRGVCALDFSADGKCLVSVGLDdfHSIVFWDWKKGEKIATT 747
           45555555.999*********95569******************778999*******************977788889*********** PP
   S: 91   kghedsvlslsfspsg.dklvsGshdrtirvwdletgqclee....tlsghdgvvncvvvhpdgnllvsGslDrtvrlWdlktgkllrt 174
           +gh+d++  ++ +p   dklv+ +  + i+ w+   g   ++       g+ ++ +cv++   ++l++sG++ + + +W  k   ll+t
   Q: 748  RGHKDKIFVVKCNPHHvDKLVTVG-MKHIKFWQQAGGGFTSKrgifGSVGKLETMMCVSYGRMEDLVFSGAATGDIFIW--KDILLLKT 833
           **************7769999887.999****9888888877998777889999*************************..8899**** PP
   S: 175  ltgghtdsvyslsfdsngkelvsgsldgtvklwdlqtgecvrtlnght 222
            +  h+++v  +   +  k +v+g++dg v+lwd   ++c++t+   +
   Q: 834  VKA-HDGPVFAMYALD--KGFVTGGKDGIVELWDDMFERCLKTYAIKR 878
           *98.******999888..57********************99997655 PP

Organism

Equus caballus

Protein Sequence
(Fasta)

SLALHPDKTL VATGQVGKEP YICIWDSYNV QTVSILKDVH THGVACLAFD SDGQVLVVIE 60
FLTKLNECVR VKKQVQPYSL DSVHWNRIFD ISWDPYQPNR VVSCGVKHIK FWTLCGNALT 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

AGCCTTGCCT TACACCCAGA TAAAACTCTT GTTGCAACTG GCCAAGTTGG GAAGGAGCCA 60
TATATATGTA TATGGGATTC CTATAATGTC CAGACTGTGT CTATTCTTAA AGATGTCCAT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0677--Repeat
KW-0853--WD repeat

Interpro

IPR024977--Apc4_WD40_dom
IPR005108--HELP
IPR011047--Quinoprotein_ADH-like_supfam
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF12894--ANAPC4_WD40
PF03451--HELP
PF00400--WD40

SMART

SM00320--WD40

Gene Ontology

GO:0015630--C:microtubule cytoskeleton
GO:0008017--F:microtubule binding

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001387	Ailuropoda melanoleuca	96.89	0.00e+00	3700.00
IUUC-Apl-003604	Anas platyrhynchos	93.11	0.00e+00	3551.00
IUUC-Aca-004572	Anolis carolinensis	88.73	0.00e+00	3444.00
IUUC-Ame-010713	Astyanax mexicanus	79.14	0.00e+00	3051.00
IUUC-Bta-012812	Bos taurus	96.68	0.00e+00	3691.00
IUUC-Cja-019191	Callithrix jacchus	96.05	0.00e+00	3679.00
IUUC-Cfa-020041	Canis familiaris	96.84	0.00e+00	3425.00
IUUC-Csa-023689	Chlorocebus sabaeus	95.81	0.00e+00	3675.00
IUUC-Cho-025038	Choloepus hoffmanni	97.91	0.00e+00	1502.00
IUUC-Cin-025205	Ciona intestinalis	60.77	0.00e+00	2412.00
IUUC-Csv-026014	Ciona savignyi	61.91	0.00e+00	2432.00
IUUC-Dno-029982	Dasypus novemcinctus	94.96	0.00e+00	3622.00
IUUC-Fca-036307	Felis catus	97.16	0.00e+00	3699.00
IUUC-Fal-037332	Ficedula albicollis	91.91	0.00e+00	3502.00
IUUC-Gmo-039057	Gadus morhua	72.96	0.00e+00	2800.00
IUUC-Gac-042555	Gasterosteus aculeatus	78.54	0.00e+00	3063.00
IUUC-Ggo-045107	Gorilla gorilla	96.37	0.00e+00	3679.00
IUUC-Hsa-046482	Homo sapiens	96.53	0.00e+00	3684.00
IUUC-Itr-049023	Ictidomys tridecemlineatus	95.32	0.00e+00	3685.00
IUUC-Loc-052642	Lepisosteus oculatus	86.94	0.00e+00	3323.00
IUUC-Laf-053649	Loxodonta africana	96.00	0.00e+00	3611.00
IUUC-Mcc-055361	Macaca mulatta	97.50	0.00e+00	3379.00
IUUC-Meu-056618	Macropus eugenii	78.11	0.00e+00	1704.00
IUUC-Mga-059202	Meleagris gallopavo	92.09	0.00e+00	3543.00
IUUC-Mmr-060729	Microcebus murinus	96.63	0.00e+00	3690.00
IUUC-Mdo-062462	Monodelphis domestica	94.26	0.00e+00	3620.00
IUUC-Mmu-063865	Mus musculus	95.32	0.00e+00	3664.00
IUUC-Mpu-066724	Mustela putorius furo	97.42	0.00e+00	3707.00
IUUC-Mlu-067816	Myotis lucifugus	97.26	0.00e+00	3721.00
IUUC-Opr-070213	Ochotona princeps	92.30	0.00e+00	1942.00
IUUC-Ont-071928	Oreochromis niloticus	78.42	0.00e+00	3106.00
IUUC-Oan-073563	Ornithorhynchus anatinus	93.65	0.00e+00	3588.00
IUUC-Ocu-074531	Oryctolagus cuniculus	96.53	0.00e+00	3688.00
IUUC-Ola-086943	Oryzias latipes	77.37	0.00e+00	3076.00
IUUC-Olu-087860	Ostreococcus lucimarinus	39.01	5.00e-118	418.00
IUUC-Oga-088665	Otolemur garnettii	96.11	0.00e+00	3660.00
IUUC-Oar-090429	Ovis aries	96.84	0.00e+00	3697.00
IUUC-Ptr-091168	Pan troglodytes	86.94	0.00e+00	3259.00
IUUC-Pan-092788	Papio anubis	97.45	0.00e+00	3062.00
IUUC-Psi-093281	Pelodiscus sinensis	91.37	0.00e+00	3478.00
IUUC-Pma-094424	Petromyzon marinus	72.83	5.00e-125	440.00
IUUC-Pab-098561	Pongo abelii	95.10	0.00e+00	3168.00
IUUC-Rno-105002	Rattus norvegicus	94.42	0.00e+00	3650.00
IUUC-Sha-107105	Sarcophilus harrisii	91.65	0.00e+00	3497.00
IUUC-Ssc-116282	Sus scrofa	97.05	0.00e+00	3703.00
IUUC-Tgu-116807	Taeniopygia guttata	92.32	0.00e+00	3516.00
IUUC-Tru-118040	Takifugu rubripes	77.18	0.00e+00	3011.00
IUUC-Tni-120118	Tetraodon nigroviridis	74.53	0.00e+00	2980.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence