iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Gac-042555

UUCD1 version

UUC-GaA-01065

Ensembl Protein ID

ENSGACP00000026319.1

UniProt Accession

G3Q8V5; G3Q8V5_GASAC

Protein Name

Uncharacterized protein

Gene Name

EML6 (1 of many)

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSGACG00000019918.1	ENSGACT00000026370.1	ENSGACP00000026319.1
ENSGACG00000019918.1	ENSGACT00000026372.1	ENSGACP00000026321.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	2.90e-56	185.3	327	359
UBD/Beta-Prp	1.50e-129	431.9	59	265

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 5    svtclaf.sd.tllvsGsdDgtikvWDlrtgvl 35
           + ++l++ +  +  v+GsdD ++++W+l +++l
   Q: 327  ELWSLDLhPKqPVAVTGSDDRSVRLWSLPDHTL 359
           5788888866699**************988766 PP

UBD/Beta-Prp

   S: 7    ghhksvitcvkfspdksllatg..srdgtikvwdvttgkllrsl.sgheaevtavkfspdgkilvtgseD..rtikvwdlstgkcvhtl 90
           gh+++ i+ ++++pdk ++atg  ++d  i +wd+ ++++++ l   h+ +v+++ f++dg+ +v+++ D  +t++vwd + g  +   
   Q: 59   GHNDDIIS-LAIHPDKVQVATGqvGKDPFICIWDTYSMQTVSILrDVHTHGVACLAFDSDGQRIVSVGLDakNTLCVWDWRRGRVIAMA 146
           78888888.99**********95557999***************889****************************************** PP
   S: 91   kghedsvlslsfsp.sgdklvsGshdrtirvwdletgqclee....tlsghdgvvncvvvhpdgnllvsGslDrtvrlWdlktgkllrt 174
           +gh+d++ +++++p ++++lvs + ++ i+ w l  +    +     ++g  +++ cv++ + + l  sG+l++ v +W+    +l+rt
   Q: 147  TGHSDRIFDVAWDPfQSSRLVSCG-VKHIKFWTLCGNALTPKrgvfGKAGDLQTILCVSTAK-EELTYSGALNGDVYVWRG--VTLIRT 231
           **************8889999998.9********9999999999655666666666666555.59**************66..99**** PP
   S: 175  ltgghtdsvyslsfdsngkelvsgsldgtvklwdlq 210
            + +h   + s+   ++g  +++g++dg ++lwd+ 
   Q: 232  VQAAHGAGIFSMHSCEEG--FATGGRDGCIRLWDVD 265
           *************99965..**************85 PP

Organism

Gasterosteus aculeatus

Protein Sequence
(Fasta)

MSDKTAPRCQ LRLEWIHGYR GHQCRNNLYY TAGKEVVYFV AGVGVVYNTR EHTQKFYLGH 60
NDDIISLAIH PDKVQVATGQ VGKDPFICIW DTYSMQTVSI LRDVHTHGVA CLAFDSDGQR 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGTCGGACA AGACGGCGCC GCGCTGCCAG CTGAGGCTGG AATGGATCCA CGGTTACCGA 60
GGACACCAAT GCCGTAACAA CCTGTACTAC ACCGCCGGGA AGGAGGTGGT TTACTTCGTG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0677--Repeat
KW-0853--WD repeat

Interpro

IPR011042--6-blade_b-propeller_TolB-like
IPR024977--Apc4_WD40_dom
IPR005108--HELP
IPR011045--N2O_reductase_N
IPR011047--Quinoprotein_ADH-like_supfam
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF12894--ANAPC4_WD40
PF03451--HELP
PF00400--WD40

SMART

SM00320--WD40

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001387	Ailuropoda melanoleuca	80.40	0.00e+00	3212.00
IUUC-Apl-003604	Anas platyrhynchos	79.77	0.00e+00	3185.00
IUUC-Aca-004572	Anolis carolinensis	76.94	0.00e+00	3110.00
IUUC-Ame-010713	Astyanax mexicanus	85.61	0.00e+00	3424.00
IUUC-Bta-012812	Bos taurus	80.19	0.00e+00	3208.00
IUUC-Cja-019191	Callithrix jacchus	79.81	0.00e+00	3172.00
IUUC-Cfa-020041	Canis familiaris	80.53	0.00e+00	2986.00
IUUC-Csa-023689	Chlorocebus sabaeus	79.34	0.00e+00	3095.00
IUUC-Cin-025205	Ciona intestinalis	59.68	0.00e+00	2404.00
IUUC-Csv-026014	Ciona savignyi	60.33	0.00e+00	2417.00
IUUC-Dno-029982	Dasypus novemcinctus	78.54	0.00e+00	3049.00
IUUC-Eca-034161	Equus caballus	78.54	0.00e+00	3047.00
IUUC-Fca-036307	Felis catus	80.50	0.00e+00	3218.00
IUUC-Fal-037332	Ficedula albicollis	79.70	0.00e+00	3142.00
IUUC-Gmo-039057	Gadus morhua	84.21	0.00e+00	3314.00
IUUC-Ggo-045107	Gorilla gorilla	80.30	0.00e+00	3212.00
IUUC-Hsa-046482	Homo sapiens	80.35	0.00e+00	3212.00
IUUC-Itr-049023	Ictidomys tridecemlineatus	78.47	0.00e+00	3096.00
IUUC-Loc-052642	Lepisosteus oculatus	84.24	0.00e+00	3345.00
IUUC-Laf-053649	Loxodonta africana	78.68	0.00e+00	3137.00
IUUC-Meu-056618	Macropus eugenii	67.00	0.00e+00	1538.00
IUUC-Mga-059202	Meleagris gallopavo	78.91	0.00e+00	3058.00
IUUC-Mmr-060729	Microcebus murinus	78.70	0.00e+00	3189.00
IUUC-Mdo-062462	Monodelphis domestica	79.69	0.00e+00	3112.00
IUUC-Mmu-063865	Mus musculus	80.14	0.00e+00	3226.00
IUUC-Mpu-066724	Mustela putorius furo	80.55	0.00e+00	3219.00
IUUC-Mlu-067816	Myotis lucifugus	79.76	0.00e+00	3196.00
IUUC-Opr-070213	Ochotona princeps	77.51	0.00e+00	1680.00
IUUC-Oan-073563	Ornithorhynchus anatinus	80.05	0.00e+00	3198.00
IUUC-Ocu-074531	Oryctolagus cuniculus	80.25	0.00e+00	3207.00
IUUC-Oga-088665	Otolemur garnettii	79.52	0.00e+00	3091.00
IUUC-Oar-090429	Ovis aries	80.30	0.00e+00	3212.00
IUUC-Psi-093281	Pelodiscus sinensis	78.94	0.00e+00	3174.00
IUUC-Pma-094424	Petromyzon marinus	68.84	3.00e-116	410.00
IUUC-Pfo-096150	Poecilia formosa	92.77	0.00e+00	3534.00
IUUC-Rno-105002	Rattus norvegicus	79.99	0.00e+00	3206.00
IUUC-Sha-107105	Sarcophilus harrisii	77.42	0.00e+00	3003.00
IUUC-Ssc-116282	Sus scrofa	80.06	0.00e+00	3115.00
IUUC-Tgu-116807	Taeniopygia guttata	79.99	0.00e+00	3179.00
IUUC-Tru-118040	Takifugu rubripes	92.01	0.00e+00	3599.00
IUUC-Tni-120118	Tetraodon nigroviridis	88.10	0.00e+00	3512.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence