iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Oar-090429

Ensembl Protein ID

ENSOARP00000003376.1

UniProt Accession

W5NYX8; W5NYX8_SHEEP

Genbank Protein ID

ENSOARP00000003376

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AMGL01077401

Gene Name

EML6

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSOARG00000003133.1	ENSOART00000003440.1	ENSOARP00000003376.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	2.10e-58	191.8	105	144
UBD/Beta-Prp	5.30e-134	446.3	57	264

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 2    Htdsvtclaf.sd.tllvsGsdD..gtikvWDlrtgvllk 37
           Ht +v cl f sd  +l+s + D  +t+ +WD+r+g+ll 
   Q: 105  HTHGVACLTFdSDgQRLASVGLDakNTVCIWDWRKGKLLA 144
           99*********999*******9999***********9875 PP

UBD/Beta-Prp

   S: 5    lkghhksvitcvkfspdksllatgs..rdgtikvwdvttgkllrsl.sgheaevtavkfspdgkilvtgseD..rtikvwdlstgkcvh 88
           + gh+++ i+ ++ +pdk+l+atg   +   i +wd  + ++++ l   h+ +v++++f++dg+ l++++ D  +t+++wd ++gk + 
   Q: 57   FLGHNDDIIS-LALHPDKTLVATGQvgKEPYICIWDSYNVQTVSILkDVHTHGVACLTFDSDGQRLASVGLDakNTVCIWDWRKGKLLA 144
           5578888888.9999********96115567***************777**************************************** PP
   S: 89   tlkghedsvlslsfspsg.dklvsGshdrtirvwdletgqclee..tlsghdgvvncvvvhpdg.nllvsGslDrtvrlWdlktgkllr 173
           + +gh+d++ ++s++p++ +++vs   ++ i+ w l  +    +  ++ ++ ++ +++++ + + ++  sG+l++ + +W+    +l+r
   Q: 145  SATGHSDRIFDISWDPYQpNRVVSC-GVKHIKFWTLCGNALTAKrgIFGKTGDLQTILCLACAKeDITYSGALNGDIYVWKG--LNLVR 230
           ****************994555555.5*******99999999889976666666666666666669**************66..99*** PP
   S: 174  tltgghtdsvyslsfdsngkelvsgsldgtvklwdl 209
           t +g+h   + s+   ++g  +++g++dg ++lwd 
   Q: 231  TIQGAHSAGIFSMYACEEG--FATGGRDGCIRLWDT 264
           *************999965..*************95 PP

Organism

Ovis aries

Protein Sequence
(Fasta)

MADRTAPSCQ LRLEWVYGYR GHQCRNNLYY TAGKEVVYFV AGVGVVYNTR EHSQKFFLGH 60
NDDIISLALH PDKTLVATGQ VGKEPYICIW DSYNVQTVSI LKDVHTHGVA CLTFDSDGQR 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGGCGGATC GGACAGCTCC CAGCTGCCAG CTCCGGCTGG AGTGGGTGTA CGGGTACCGG 60
GGTCACCAGT GCCGCAACAA CCTGTACTAC ACCGCCGGCA AGGAGGTGGT CTACTTTGTG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0677--Repeat
KW-0853--WD repeat

Interpro

IPR011042--6-blade_b-propeller_TolB-like
IPR024977--Apc4_WD40_dom
IPR005108--HELP
IPR011047--Quinoprotein_ADH-like_supfam
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF12894--ANAPC4_WD40
PF03451--HELP
PF00400--WD40

SMART

SM00320--WD40

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001387	Ailuropoda melanoleuca	98.57	0.00e+00	3877.00
IUUC-Apl-003604	Anas platyrhynchos	94.10	0.00e+00	3705.00
IUUC-Aca-004572	Anolis carolinensis	89.91	0.00e+00	3597.00
IUUC-Ame-010713	Astyanax mexicanus	80.69	0.00e+00	3229.00
IUUC-Bta-012812	Bos taurus	99.64	0.00e+00	3899.00
IUUC-Cja-019191	Callithrix jacchus	97.57	0.00e+00	3819.00
IUUC-Cfa-020041	Canis familiaris	98.47	0.00e+00	3600.00
IUUC-Cre-022931	Chlamydomonas reinhardtii	34.82	2.00e-101	365.00
IUUC-Csa-023689	Chlorocebus sabaeus	97.23	0.00e+00	3734.00
IUUC-Cho-025038	Choloepus hoffmanni	97.26	0.00e+00	1494.00
IUUC-Cin-025205	Ciona intestinalis	62.13	0.00e+00	2585.00
IUUC-Csv-026014	Ciona savignyi	63.70	0.00e+00	2609.00
IUUC-Dno-029982	Dasypus novemcinctus	95.91	0.00e+00	3671.00
IUUC-Eca-034161	Equus caballus	96.84	0.00e+00	3696.00
IUUC-Fca-036307	Felis catus	98.67	0.00e+00	3877.00
IUUC-Fal-037332	Ficedula albicollis	92.89	0.00e+00	3626.00
IUUC-Gmo-039057	Gadus morhua	74.94	0.00e+00	2996.00
IUUC-Gac-042555	Gasterosteus aculeatus	80.30	0.00e+00	3233.00
IUUC-Ggo-045107	Gorilla gorilla	97.96	0.00e+00	3860.00
IUUC-Hsa-046482	Homo sapiens	98.11	0.00e+00	3861.00
IUUC-Itr-049023	Ictidomys tridecemlineatus	96.27	0.00e+00	3731.00
IUUC-Loc-052642	Lepisosteus oculatus	88.24	0.00e+00	3483.00
IUUC-Laf-053649	Loxodonta africana	95.82	0.00e+00	3739.00
IUUC-Mcc-055361	Macaca mulatta	98.02	0.00e+00	3387.00
IUUC-Meu-056618	Macropus eugenii	79.05	0.00e+00	1808.00
IUUC-Mga-059202	Meleagris gallopavo	93.09	0.00e+00	3583.00
IUUC-Mmr-060729	Microcebus murinus	95.66	0.00e+00	3826.00
IUUC-Mdo-062462	Monodelphis domestica	95.46	0.00e+00	3677.00
IUUC-Mmu-063865	Mus musculus	96.78	0.00e+00	3835.00
IUUC-Mpu-066724	Mustela putorius furo	98.72	0.00e+00	3880.00
IUUC-Mlu-067816	Myotis lucifugus	98.07	0.00e+00	3872.00
IUUC-Opr-070213	Ochotona princeps	94.74	0.00e+00	2003.00
IUUC-Ont-071928	Oreochromis niloticus	79.64	0.00e+00	3244.00
IUUC-Oan-073563	Ornithorhynchus anatinus	95.37	0.00e+00	3768.00
IUUC-Ocu-074531	Oryctolagus cuniculus	98.01	0.00e+00	3857.00
IUUC-Ola-086943	Oryzias latipes	79.01	0.00e+00	3146.00
IUUC-Olu-087860	Ostreococcus lucimarinus	38.51	5.00e-117	414.00
IUUC-Oga-088665	Otolemur garnettii	96.79	0.00e+00	3704.00
IUUC-Ptr-091168	Pan troglodytes	88.80	0.00e+00	3435.00
IUUC-Pan-092788	Papio anubis	97.89	0.00e+00	3067.00
IUUC-Psi-093281	Pelodiscus sinensis	92.27	0.00e+00	3658.00
IUUC-Pma-094424	Petromyzon marinus	72.83	1.00e-124	438.00
IUUC-Pab-098561	Pongo abelii	98.37	0.00e+00	3346.00
IUUC-Pca-100177	Procavia capensis	86.19	0.00e+00	1538.00
IUUC-Rno-105002	Rattus norvegicus	95.91	0.00e+00	3820.00
IUUC-Sha-107105	Sarcophilus harrisii	92.84	0.00e+00	3558.00
IUUC-Ssc-116282	Sus scrofa	98.84	0.00e+00	3776.00
IUUC-Tgu-116807	Taeniopygia guttata	94.08	0.00e+00	3692.00
IUUC-Tru-118040	Takifugu rubripes	78.83	0.00e+00	3175.00
IUUC-Tni-120118	Tetraodon nigroviridis	76.50	0.00e+00	3148.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence