iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Aca-005349

UUCD1 version

UUC-AnC-00940

Ensembl Protein ID

ENSACAP00000012888.3

UniProt Accession

G1KNA2; G1KNA2_ANOCA

Protein Name

Uncharacterized protein

Gene Name

UBA6

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSACAG00000013037.3	ENSACAT00000013146.3	ENSACAP00000012888.3

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E1	1.00e-207	690.2	412	899

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

   S: 1    YDRQirlwGeeaqeklksakvllvGagglGcEllKnLvlaGv......gsitvvDmdtvevsnlnrqFLfraedvgksKAevaaealke 83
           YD +++++G+  ++kl++ +v+lvG+g++GcE+lKn++l+Gv      g++t++D d +e+snlnrqFLfr+++++k+K+ +aa+a  +
   Q: 412  YDALRACIGDSLCQKLQNLNVFLVGCGAIGCEMLKNFALLGVgtgqerGMVTITDPDLIEKSNLNRQFLFRPHHIQKPKSYTAAAATLN 500
           9**************************************************************************************** PP
   S: 84   lnpdvnveaheesiteleeeiv...FfkkfdvVvlaldnrearrkvnrlclnarvpliesgtlGllGqvrviikgltecyscsddppqk 169
           +np+++++++ +++++ +e+i+   F++k dvVv+aldn+earr+++++c+++ +pl++sgt+G++G+++vi+++lte+y++++dpp++
   Q: 501  INPQMKIDSYLNKVCPATENIYnddFYTKQDVVVTALDNVEARRYIDSRCVANLRPLLDSGTMGTKGHTEVILPHLTESYNSHRDPPEE 589
           ***************************************************************************************** PP
   S: 170  tiPfctlketpnaaehtiewa............vlfnklleeeageeevlekldseekeegkdkvkselksedeenfeeaieiavkafa 246
           +iPfctlk++p+a ehti+wa            +lfnk++ +++++eevl++++s e++eg ++v  +  s++++++ +++e+a+ +f+
   Q: 590  EIPFCTLKSFPAATEHTIQWArdkfessfshkpSLFNKFWRTYSSAEEVLQRIKSGESLEGSFQV-IKCLSRRPRSWPQCVELARLKFE 677
           *****************************************************************.99999****************** PP
   S: 247  kttinsikqllksfecdivtkskspfwv.........................................................sfcs 278
           k++++++ qll+sf+ d + k++s fw+                                                         +f +
   Q: 678  KYFNHKALQLLHSFPIDTRLKDGSLFWQspkrppfpiqfdfndplhysfmlstaklfatiycvpftekdmseetilkiiselkiqEFRP 766
           *************************************************************************************999* PP
   S: 279  naealqvpekvekdeevvkasap.....lylllralerfekkkgrkpgelsfekddds..avdlvtaaanlraeslgiepkldddlike 360
            ++ +q++e+v k+  +  +s++      +l++++  + ++k++++++elsfekddds  ++d++taa+nlra +++iep +d+ ++k+
   Q: 767  SNKVVQTDETVRKPDPIPVSSEDernavTQLETAIFANEATKDDLQMKELSFEKDDDSngHIDFITAASNLRARMYNIEP-ADRLKTKR 854
           ******9999999998887777788999****************************************************.******** PP
   S: 361  iagniipaiattnavvgGlaaqEviKvvsg.kfeplknfflfdae 404
           iag+iipaiat +a+v+Gl+a+E+iKvv g +f+++kn+f+++a+
   Q: 855  IAGKIIPAIATSTAAVSGLVALELIKVVGGyPFQAYKNCFFNLAI 899
           *****************************************9876 PP

Organism

Anolis carolinensis

Protein Sequence
(Fasta)

MAADSMEIDD ALYSRQRYVL GDRAMQKMAQ SHVFLSGMGG LGVEIAKNIV LAGIKTLTIH 60
DTKQCKAWDL GTNFFVHEDD ILNLRNRAEA THHRIAELNP YVQVMSSTAP LNEVTDISFL 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GCTCAGAAAA TACAGCGTGT CACAATGGCA GCAGATTCAA TGGAAATAGA TGATGCTTTG 60
TACAGGTAAG AATGTGTGTC TTGCTTCTTG GTATAAAAAC AAAGGATAGA TAAATATGAC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR032420--E1_4HB
IPR032418--E1_FCCH
IPR016040--NAD(P)-bd_dom
IPR000594--ThiF_NAD_FAD-bd
IPR018965--Ub-activating_enz_E1_C
IPR019572--UBA_E1_Cys
IPR018075--UBQ-activ_enz_E1
IPR000011--UBQ/SUMO-activ_enz_E1-like

Pfam

PF16191--E1_4HB
PF16190--E1_FCCH
PF09358--E1_UFD
PF00899--ThiF
PF10585--UBA_e1_thiolCys

PRINTS

PR01849--UBIQUITINACT

SMART

SM00985--UBA_e1_C

Gene Ontology

GO:0005737--C:cytoplasm
GO:0019780--F:FAT10 activating enzyme activity
GO:0004839--F:ubiquitin activating enzyme activity
GO:0021764--P:amygdala development
GO:0060996--P:dendritic spine development
GO:0021766--P:hippocampus development
GO:0007612--P:learning
GO:0007626--P:locomotory behavior
GO:0042787--P:protein ubiquitination involved in ubiquitin-dependent protein catabolic process

KEGG

acs:100565511

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001608	Ailuropoda melanoleuca	80.18	0.00e+00	1759.00
IUUC-Apl-004158	Anas platyrhynchos	86.91	0.00e+00	1831.00
IUUC-Bta-012696	Bos taurus	80.71	0.00e+00	1767.00
IUUC-Cja-019563	Callithrix jacchus	80.41	0.00e+00	1734.00
IUUC-Cfa-020951	Canis familiaris	80.22	0.00e+00	1761.00
IUUC-Cpo-022307	Cavia porcellus	78.56	0.00e+00	1699.00
IUUC-Csa-023647	Chlorocebus sabaeus	80.22	0.00e+00	1739.00
IUUC-Cho-024682	Choloepus hoffmanni	65.35	0.00e+00	798.00
IUUC-Dre-028022	Danio rerio	67.94	0.00e+00	1504.00
IUUC-Dno-029796	Dasypus novemcinctus	79.98	0.00e+00	1729.00
IUUC-Dor-030981	Dipodomys ordii	67.06	0.00e+00	1365.00
IUUC-Ete-032514	Echinops telfairi	69.73	0.00e+00	1018.00
IUUC-Eca-033697	Equus caballus	79.73	0.00e+00	1759.00
IUUC-Eeu-035323	Erinaceus europaeus	74.70	0.00e+00	1174.00
IUUC-Fca-035858	Felis catus	80.71	0.00e+00	1769.00
IUUC-Fal-036848	Ficedula albicollis	84.72	0.00e+00	1809.00
IUUC-Gmo-039326	Gadus morhua	67.25	0.00e+00	1416.00
IUUC-Gga-040747	Gallus gallus	85.60	0.00e+00	1816.00
IUUC-Gac-041406	Gasterosteus aculeatus	67.68	0.00e+00	1407.00
IUUC-Ggo-044577	Gorilla gorilla	80.23	0.00e+00	1738.00
IUUC-Hsa-046007	Homo sapiens	80.31	0.00e+00	1732.00
IUUC-Itr-048191	Ictidomys tridecemlineatus	84.64	0.00e+00	971.00
IUUC-Lch-049992	Latimeria chalumnae	74.61	0.00e+00	1568.00
IUUC-Loc-051899	Lepisosteus oculatus	71.33	0.00e+00	1553.00
IUUC-Laf-054413	Loxodonta africana	80.31	0.00e+00	1668.00
IUUC-Mcc-054656	Macaca mulatta	80.12	0.00e+00	1736.00
IUUC-Meu-056463	Macropus eugenii	68.50	0.00e+00	1353.00
IUUC-Mga-059721	Meleagris gallopavo	84.27	0.00e+00	1699.00
IUUC-Mmr-060908	Microcebus murinus	77.08	0.00e+00	1682.00
IUUC-Mdo-062096	Monodelphis domestica	81.68	0.00e+00	1782.00
IUUC-Mmu-064114	Mus musculus	80.02	0.00e+00	1754.00
IUUC-Mpu-066017	Mustela putorius furo	80.12	0.00e+00	1762.00
IUUC-Mlu-068037	Myotis lucifugus	79.53	0.00e+00	1704.00
IUUC-Nle-069494	Nomascus leucogenys	80.02	0.00e+00	1733.00
IUUC-Ont-071592	Oreochromis niloticus	69.38	0.00e+00	1479.00
IUUC-Oan-073268	Ornithorhynchus anatinus	78.73	0.00e+00	1568.00
IUUC-Ocu-074296	Oryctolagus cuniculus	80.22	0.00e+00	1770.00
IUUC-Ola-086376	Oryzias latipes	69.19	0.00e+00	1434.00
IUUC-Oga-088186	Otolemur garnettii	80.63	0.00e+00	1735.00
IUUC-Oar-089307	Ovis aries	81.19	0.00e+00	1774.00
IUUC-Ptr-090609	Pan troglodytes	80.31	0.00e+00	1734.00
IUUC-Pan-092905	Papio anubis	80.16	0.00e+00	1656.00
IUUC-Psi-093489	Pelodiscus sinensis	85.80	0.00e+00	1826.00
IUUC-Pma-094203	Petromyzon marinus	64.83	1.00e-54	204.00
IUUC-Pfo-096670	Poecilia formosa	69.44	0.00e+00	1496.00
IUUC-Pab-098418	Pongo abelii	80.02	0.00e+00	1730.00
IUUC-Pca-100889	Procavia capensis	68.01	0.00e+00	1412.00
IUUC-Pva-103144	Pteropus vampyrus	69.83	0.00e+00	1491.00
IUUC-Rno-105612	Rattus norvegicus	80.41	0.00e+00	1763.00
IUUC-Sha-107388	Sarcophilus harrisii	81.42	0.00e+00	1771.00
IUUC-Sar-113128	Sorex araneus	78.75	0.00e+00	1726.00
IUUC-Ssc-116117	Sus scrofa	80.82	0.00e+00	1764.00
IUUC-Tgu-116565	Taeniopygia guttata	84.92	0.00e+00	1817.00
IUUC-Tru-118591	Takifugu rubripes	67.55	0.00e+00	1429.00
IUUC-Tsy-119436	Tarsius syrichta	72.49	0.00e+00	1514.00
IUUC-Tni-120880	Tetraodon nigroviridis	66.63	0.00e+00	1418.00
IUUC-Tbe-127714	Tupaia belangeri	63.27	0.00e+00	1300.00
IUUC-Ttr-129159	Tursiops truncatus	70.13	0.00e+00	1471.00
IUUC-Vpa-130716	Vicugna pacos	78.31	0.00e+00	1665.00
IUUC-Xtr-132947	Xenopus tropicalis	71.78	0.00e+00	1550.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence