iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Mac-065014

Ensembl Protein ID

GSMUA_Achr6P22600_001

UniProt Accession

M0T9A8; M0T9A8_MUSAM

Protein Name

E3 ubiquitin-protein ligase

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
GSMUA_Achr6G22600_001	GSMUA_Achr6T22600_001	GSMUA_Achr6P22600_001

Status

Unreviewed

Classification

Family	Identity	E-Value	Score	Source Orthology
E3 activity/RING/RING	36.11	4.00e-39	159.00	IUUC-Dme-031700

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Organism

Musa acuminata

Functional Description
(View)

E3 ubiquitin-protein ligase that mediates ubiquitination and subsequent proteasomal degradation of target proteins. E3 ubiquitin ligases accept ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates.

Protein Sequence
(Fasta)

MESDSVDCVS LTDGLDEEEV TQHRHPFPKP HGSGAPPLPG IAPATSVHEL LECPVCTNSM 60
YPPIHQCRNG HTLCSTCKSR VHNRCPTCRQ ELGDIRCLAL EKVAESLELP CKYSTLGCPE 120

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Nucleotide Sequence
(Fasta)

TCTCTCTCTC TCTCTCTCTC TCTCTCCACC TGTTTTCCCT GCAAAATCTC TCCTTTTTTC 60
CCCTGGGATT CCCCTCCCGA TCGAGACGGG GAGGGTCCGG CGGTGGAGAG GGGTTTTGAT 120

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Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0479--Metal-binding
KW-1185--Reference proteome
KW-0833--Ubl conjugation pathway
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR018121--7-in-absentia-prot_TRAF-dom
IPR004162--SINA-like
IPR008974--TRAF-like
IPR001841--Znf_RING
IPR013083--Znf_RING/FYVE/PHD
IPR013010--Znf_SIAH

PROSITE

PS50089--ZF_RING_2
PS51081--ZF_SIAH

Pfam

PF03145--Sina

Gene Ontology

GO:0005634--C:nucleus
GO:0004842--F:ubiquitin-protein transferase activity
GO:0008270--F:zinc ion binding
GO:0007275--P:multicellular organism development
GO:0006511--P:ubiquitin-dependent protein catabolic process

KEGG

mus:103988806

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000061	Aegilops tauschii	75.46	1.00e-126	444.00
IUUC-Aca-005014	Anolis carolinensis	36.64	4.00e-42	164.00
IUUC-Ame-011196	Astyanax mexicanus	35.05	3.00e-43	168.00
IUUC-Cel-018320	Caenorhabditis elegans	34.56	2.00e-37	149.00
IUUC-Cfa-020642	Canis familiaris	36.64	2.00e-42	165.00
IUUC-Cho-024933	Choloepus hoffmanni	36.84	5.00e-39	154.00
IUUC-Cin-025674	Ciona intestinalis	36.59	6.00e-41	160.00
IUUC-Csv-026233	Ciona savignyi	36.55	2.00e-41	161.00
IUUC-Dre-028041	Danio rerio	35.40	1.00e-43	169.00
IUUC-Dor-030489	Dipodomys ordii	32.79	4.00e-21	93.60
IUUC-Dme-031700	Drosophila melanogaster	36.84	5.00e-37	147.00
IUUC-Ete-032423	Echinops telfairi	37.50	1.00e-41	162.00
IUUC-Eeu-035314	Erinaceus europaeus	37.50	1.00e-41	162.00
IUUC-Gmo-039091	Gadus morhua	37.07	7.00e-39	153.00
IUUC-Hvu-047574	Hordeum vulgare	75.46	1.00e-126	444.00
IUUC-Loc-052191	Lepisosteus oculatus	35.19	7.00e-43	167.00
IUUC-Meu-055922	Macropus eugenii	36.03	2.00e-37	148.00
IUUC-Mdo-061971	Monodelphis domestica	37.25	2.00e-39	155.00
IUUC-Mpu-066331	Mustela putorius furo	36.46	2.00e-42	166.00
IUUC-Opr-070341	Ochotona princeps	27.85	6.00e-12	63.90
IUUC-Oan-073701	Ornithorhynchus anatinus	26.17	5.00e-12	63.90
IUUC-Oga-088114	Otolemur garnettii	37.13	2.00e-44	172.00
IUUC-Pma-094387	Petromyzon marinus	35.88	1.00e-41	162.00
IUUC-Pca-100328	Procavia capensis	36.44	7.00e-37	147.00
IUUC-Pva-102368	Pteropus vampyrus	38.14	5.00e-12	64.30
IUUC-Ssc-116441	Sus scrofa	36.84	4.00e-39	154.00
IUUC-Tru-118250	Takifugu rubripes	35.88	5.00e-41	160.00
IUUC-Tsy-119548	Tarsius syrichta	36.08	6.00e-10	57.00
IUUC-Tni-120488	Tetraodon nigroviridis	36.43	3.00e-40	158.00
IUUC-Tae-123647	Triticum aestivum	75.46	1.00e-126	444.00
IUUC-Ttr-129166	Tursiops truncatus	37.08	9.00e-40	156.00

Created Date

25-Jun-2017

Functional Description

Protein Fasta Sequence

Nucleotide Fasta Sequence