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Basic Information Integrated Annotations

Tag Content
UUCD2 ID IUUC-Rno-105540
UUCD1 version UUC-RaN-00440
Ensembl Protein ID ENSRNOP00000056931.4
UniProt Accession D3ZI42; D3ZI42_RAT
Genbank Protein ID ENSRNOP00000056931
Protein Name Leucine-rich repeat and sterile alpha motif-containing 1
Genbank Nucleotide ID AABR07051452
Gene Name Lrsam1
Ensembl Information
Ensembl Gene ID Ensembl Transcript ID Ensembl Protein ID
ENSRNOG00000022312.6 ENSRNOT00000060186.4 ENSRNOP00000056931.4
Annotation
Single Nucleotide Polymorphisms (SNP)
dbSNP
mRNA Expression
GEOArrayExpress
DNA & RNA Element
RAID2
Protein Expression/Proteomics
GPMDB
Status Unreviewed
Classification
Family Identity E-Value Score Source Orthology
E3 activity/RING/RING 85.99 0.00e+00 1095.00 IUUC-Hsa-046865
Active Site
Position(s) Description Evidence
N/A N/A N/A
Organism Rattus norvegicus
Protein Sequence
(Fasta)
MPLFFRKRKP SEEARKRLEY QMCLAKEAGA DDILDISKCE LSEIPFGAFA TCKVLQKKVR 60
WIRAHHLGAC FLPTACLIYS VSSRQVLDLH DNQLTALPDD IGQLTALQVL NVERNQLTHL 120
It may take some time, please wait.

Protein Fasta Sequence



>IUUC-Rno-105540|E3,RING|Rattus norvegicus
Please wait for a moment...
Nucleotide Sequence
(Fasta)
ATGCCTCTCT TCTTTCGGAA GCGGAAACCC AGTGAGGAAG CTCGGAAACG CCTGGAGTAC 60
CAGATGTGTC TGGTAAGGCA CAGAGTATTG TCTCTGACAC CCTGAAATGT CTCCAGGGGT 120
It may take some time, please wait.

Nucleotide Fasta Sequence



>IUUC-Rno-105540|E3,RING|Rattus norvegicus
Please wait for a moment...
Sequence Source Ensembl
Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-0479--Metal-binding
KW-1267--Proteomics identification
KW-1185--Reference proteome
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR001370--BIR_rpt
IPR032675--L_dom-like
IPR001611--Leu-rich_rpt
IPR003591--Leu-rich_rpt_typical-subtyp
IPR001660--SAM
IPR013761--SAM/pointed
IPR001841--Znf_RING

PROSITE

PS51450--LRR
PS50105--SAM_DOMAIN
PS50089--ZF_RING_2

Pfam

PF13855--LRR_8
PF00536--SAM_1

SMART

SM00369--LRR_TYP

Gene Ontology

GO:0005737--C:cytoplasm
GO:0005829--C:cytosol
GO:0005886--C:plasma membrane
GO:0061630--F:ubiquitin protein ligase activity
GO:0008270--F:zinc ion binding
GO:0045806--P:negative regulation of endocytosis
GO:2000786--P:positive regulation of autophagosome assembly
GO:1904417--P:positive regulation of xenophagy
GO:0051865--P:protein autoubiquitination
GO:0030163--P:protein catabolic process
GO:0000209--P:protein polyubiquitination
GO:0007165--P:signal transduction
GO:0070086--P:ubiquitin-dependent endocytosis
GO:0046755--P:viral budding

Orthology
iUUCD ID Species Identity E-value Score
IUUC-Aml-001663 Ailuropoda melanoleuca 84.57 0.00e+00 1066.00
IUUC-Atr-002772 Amborella trichopoda 42.86 2.00e-09 56.20
IUUC-Apl-004029 Anas platyrhynchos 71.84 0.00e+00 630.00
IUUC-Aca-004487 Anolis carolinensis 60.85 0.00e+00 667.00
IUUC-Aly-005571 Arabidopsis lyrata 35.48 6.00e-12 66.60
IUUC-Ath-006853 Arabidopsis thaliana 30.19 6.00e-16 78.20
IUUC-Ame-011792 Astyanax mexicanus 53.32 0.00e+00 708.00
IUUC-Bta-012937 Bos taurus 85.89 0.00e+00 1108.00
IUUC-Bdi-014104 Brachypodium distachyon 35.09 2.00e-09 57.00
IUUC-Bol-016339 Brassica oleracea 36.08 2.00e-14 73.20
IUUC-Bra-016795 Brassica rapa 35.05 5.00e-14 72.00
IUUC-Cja-019359 Callithrix jacchus 84.35 0.00e+00 1042.00
IUUC-Cfa-020908 Canis familiaris 85.60 0.00e+00 1058.00
IUUC-Cpo-021744 Cavia porcellus 83.65 0.00e+00 1002.00
IUUC-Csa-023784 Chlorocebus sabaeus 86.40 0.00e+00 1103.00
IUUC-Cin-025241 Ciona intestinalis 36.57 1.00e-102 367.00
IUUC-Dre-027424 Danio rerio 55.49 0.00e+00 679.00
IUUC-Dno-028857 Dasypus novemcinctus 85.58 0.00e+00 1062.00
IUUC-Dor-030397 Dipodomys ordii 81.42 6.00e-106 378.00
IUUC-Ete-032958 Echinops telfairi 68.54 2.00e-150 525.00
IUUC-Eca-033505 Equus caballus 85.85 0.00e+00 1116.00
IUUC-Eeu-035089 Erinaceus europaeus 75.64 0.00e+00 838.00
IUUC-Fca-036318 Felis catus 85.60 0.00e+00 1060.00
IUUC-Fal-037299 Ficedula albicollis 68.45 0.00e+00 773.00
IUUC-Gmo-038494 Gadus morhua 56.53 0.00e+00 656.00
IUUC-Gga-041180 Gallus gallus 69.14 0.00e+00 851.00
IUUC-Gac-041975 Gasterosteus aculeatus 52.39 4.00e-175 608.00
IUUC-Gma-043846 Glycine max 35.71 2.00e-10 59.70
IUUC-Ggo-045293 Gorilla gorilla 81.87 0.00e+00 1021.00
IUUC-Hsa-046865 Homo sapiens 85.58 0.00e+00 1094.00
IUUC-Hvu-047769 Hordeum vulgare 26.83 8.00e-15 74.70
IUUC-Itr-048290 Ictidomys tridecemlineatus 86.81 0.00e+00 1085.00
IUUC-Lch-049955 Latimeria chalumnae 54.10 4.00e-174 605.00
IUUC-Loc-052396 Lepisosteus oculatus 53.16 3.00e-148 518.00
IUUC-Laf-054274 Loxodonta africana 86.15 0.00e+00 1044.00
IUUC-Mcc-055328 Macaca mulatta 86.26 0.00e+00 1100.00
IUUC-Meu-056407 Macropus eugenii 71.96 3.00e-77 283.00
IUUC-Mtr-057683 Medicago truncatula 33.33 6.00e-13 68.60
IUUC-Mga-059898 Meleagris gallopavo 69.14 0.00e+00 861.00
IUUC-Mmr-061558 Microcebus murinus 86.01 0.00e+00 1095.00
IUUC-Mdo-062877 Monodelphis domestica 77.20 0.00e+00 942.00
IUUC-Mmu-063525 Mus musculus 93.13 0.00e+00 1207.00
IUUC-Mac-064501 Musa acuminata 28.80 8.00e-15 74.70
IUUC-Mpu-066491 Mustela putorius furo 83.52 0.00e+00 1021.00
IUUC-Mlu-068182 Myotis lucifugus 81.78 0.00e+00 938.00
IUUC-Nle-069349 Nomascus leucogenys 85.44 0.00e+00 1070.00
IUUC-Opr-070326 Ochotona princeps 76.92 0.00e+00 857.00
IUUC-Ont-071685 Oreochromis niloticus 55.30 0.00e+00 696.00
IUUC-Oan-072957 Ornithorhynchus anatinus 77.64 0.00e+00 946.00
IUUC-Olo-081076 Oryza longistaminata 29.90 2.00e-06 48.50
IUUC-Oni-083060 Oryza nivara 31.25 6.00e-03 37.00
IUUC-Oga-088129 Otolemur garnettii 85.71 0.00e+00 1075.00
IUUC-Oar-089353 Ovis aries 79.64 0.00e+00 978.00
IUUC-Ptr-091511 Pan troglodytes 85.99 0.00e+00 1096.00
IUUC-Pan-092251 Papio anubis 86.26 0.00e+00 1100.00
IUUC-Psi-093778 Pelodiscus sinensis 60.62 0.00e+00 681.00
IUUC-Pma-094158 Petromyzon marinus 44.39 1.00e-122 433.00
IUUC-Ppa-095427 Physcomitrella patens 33.33 3.00e-14 72.40
IUUC-Pfo-096094 Poecilia formosa 53.32 0.00e+00 638.00
IUUC-Pab-098187 Pongo abelii 81.59 0.00e+00 1012.00
IUUC-Pop-099197 Populus trichocarpa 33.65 4.00e-12 65.50
IUUC-Pca-100526 Procavia capensis 79.38 6.00e-134 471.00
IUUC-Ppe-101851 Prunus persica 40.00 2.00e-13 70.10
IUUC-Pva-102557 Pteropus vampyrus 82.17 0.00e+00 999.00
IUUC-Pgr-103622 Puccinia graminis 35.78 7.00e-12 67.00
IUUC-Pyt-104751 Pyrenophora triticirepentis 37.50 3.00e-14 74.30
IUUC-Sha-107485 Sarcophilus harrisii 76.51 0.00e+00 931.00
IUUC-Spo-108106 Schizosaccharomyces pombe 34.86 2.00e-14 74.30
IUUC-Sit-110214 Setaria italica 36.90 2.00e-10 60.10
IUUC-Sar-113098 Sorex araneus 71.19 0.00e+00 779.00
IUUC-Sbi-114187 Sorghum bicolor 39.29 1.00e-10 60.80
IUUC-Ssc-116105 Sus scrofa 80.77 0.00e+00 993.00
IUUC-Tgu-116857 Taeniopygia guttata 68.07 1.00e-175 608.00
IUUC-Tru-117930 Takifugu rubripes 50.00 0.00e+00 645.00
IUUC-Tsy-119382 Tarsius syrichta 75.32 1.00e-90 327.00
IUUC-Tni-120714 Tetraodon nigroviridis 52.38 3.00e-180 625.00
IUUC-Tca-121678 Theobroma cacao 38.54 4.00e-14 72.40
IUUC-Tae-125723 Triticum aestivum 27.18 1.00e-13 70.90
IUUC-Tbe-127528 Tupaia belangeri 75.42 1.00e-79 291.00
IUUC-Ttr-128282 Tursiops truncatus 85.52 0.00e+00 1074.00
IUUC-Vda-129866 Verticillium dahliae 37.10 2.00e-06 48.10
IUUC-Vpa-130740 Vicugna pacos 72.31 0.00e+00 723.00
IUUC-Vvi-131120 Vitis vinifera 34.44 4.00e-11 62.40
IUUC-Xtr-132037 Xenopus tropicalis 57.69 0.00e+00 660.00
Created Date 25-Jun-2017

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