iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSDARG00000103494.1	ENSDART00000168985.1	ENSDARP00000141884.1
ENSDARG00000103494.1	ENSDART00000159749.1	ENSDARP00000136694.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
DUB/USP	2.10e-93	314.1	114	745

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

DUB/USP

   S: 1    tGlkNlgNtCYmNSvLQcLsnipelrellle.kkkeklneenp......kepkgellkslqklfeelwkskkkavsprellkalkkeae 82
           +GlkN+gNtC+mN+v+QcLsn++ l+e+l   ++k +lne+        +e  ge++++l++l+++lw+++ +     +++++++k+ +
   Q: 114  QGLKNHGNTCFMNAVVQCLSNTELLAEYLGLeQYKYELNERRIngmmksEEVRGEVTDKLASLVRALWTNDYTPQLSVDFKSVVAKYGS 202
           6***************************95547888888776666665566667*********************************** PP
   S: 83   efsgyeqqDaqEflaflldqleeelkkeknkpkeeeeeedkselsde...........aeekkkkknkslisdlFqgqlksqikclecd 160
           +f+g++q+Da Efl +lld ++e+ + ++n+++++ ++++k     +           a+++++   +s++++ Fq q++s+++c++c 
   Q: 203  QFKGNAQHDALEFLLWLLDCVHEDANLSTNNNQSRNSSSSKG----SvgleesscpgpANSQQPGTRHSFVQEHFQAQYRSSLTCPHCL 287
           *************************66444333333333322....1235577899988888899999********************* PP
   S: 161  nvssreepfldlslpvpgkeetkke................................................................ 185
           ++s++++pfl +slp+p +++++++                                                                
   Q: 288  KQSNTFDPFLCISLPIPLRQTRALNvtlvfstegqrflriglavplfgsistlramvaeegklspdqviltemnsggfqrsfsdeddmt 376
           ********************99888**************************************************************** PP
   S: 186  ......................................................................................... 185
                                                                                                    
   Q: 377  sisesdviyafqvpphftrggsmrfsgyhhslpsspytadfkghrlppsgtlsteflnhggsskvlllicnvagsgqqatrfgppflmr 465
           ***************************************************************************************** PP
   S: 186  ......................................................................................... 185
                                                                                                    
   Q: 466  vertlswdhlqqsvcnklyvfqktaiikttelfkvrvvggsascsylsphdsrplchptvdralklcgpggplhvkliiewdnkikecl 554
           ***************************************************************************************** PP
   S: 186  ............................slqdcLesftkeeelegenkyycekckkkqeaekklklkklPevLilhLkRfsfseeqksr 246
                                       +l+dc++ +tkee+l  +++++c++ck+ q+   k++l++lP++LilhLkRf  ++ +k+r
   Q: 555  fgniqeeviedaesvriqqqnhvqqhscTLDDCFQLYTKEEQLAPDDAWKCPHCKQMQQGMVKMSLWTLPDILILHLKRF--RQVGKRR 641
           ********************************************************************************..9999*** PP
   S: 247  ekinkkvefple.Ldlspfctspeekqke.............kkkYeLiavvvHsGslssGHYvayvknekgk.WllfdDskVtevkee 320
           +k+++ + fp + Ld++p++++++++ k+             +  Y+L+av++H+G++++GHY+ay++n+ ++ W+ +dDs+V+ v+ee
   Q: 642  NKLSTLIRFPVSaLDMTPHVVKRSQSMKNlaplpstwkhgetDFLYDLYAVCNHHGGMHGGHYTAYCRNSVDGhWYSYDDSSVEIVPEE 730
           **********************999998899**********9***************************65555*************** PP
   S: 321  evleetgstaYvlfYkrr 338
           e ++   + aY+lfY+rr
   Q: 731  ELCT---RGAYILFYQRR 745
           ****...*********96 PP

Organism

Danio rerio

Protein Sequence
(Fasta)

MDSLRETRKQ TIKAKSAKRK NKTHKSQKLF RRKSLKSLGN FMSRIVKTLG TLAHLGDADQ 60
PDAAAEDDDG GFGDTASVHN SGNYRESSAR KSSSYGSVKE RLSWCYGEKT PGVQGLKNHG 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CATGGAGTTC AGCCCAGTGT ATTTCCAGGT GCGTACGAGA GCGTCATGGA TAAATCGAAA 60
GTAGCGCAGC AGAGAACAGC GATAAGGAAT GTCGGGGACG CGATAATTAC GAGCCTCGGT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR001394--Peptidase_C19_UCH
IPR018200--USP_CS
IPR028889--USP_dom

PROSITE

PS00972--USP_1
PS00973--USP_2
PS50235--USP_3

Pfam

PF00443--UCH

Gene Ontology

GO:0036459--F:thiol-dependent ubiquitinyl hydrolase activity
GO:0016579--P:protein deubiquitination
GO:0006511--P:ubiquitin-dependent protein catabolic process

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001922	Ailuropoda melanoleuca	45.35	0.00e+00	761.00
IUUC-Aca-004436	Anolis carolinensis	52.86	0.00e+00	829.00
IUUC-Ame-011153	Astyanax mexicanus	61.36	0.00e+00	1172.00
IUUC-Bta-013560	Bos taurus	48.99	0.00e+00	883.00
IUUC-Cja-018737	Callithrix jacchus	49.95	0.00e+00	871.00
IUUC-Cfa-020347	Canis familiaris	46.85	0.00e+00	837.00
IUUC-Csa-023656	Chlorocebus sabaeus	49.73	0.00e+00	878.00
IUUC-Cho-024864	Choloepus hoffmanni	47.89	1.00e-153	537.00
IUUC-Csv-026086	Ciona savignyi	39.18	3.00e-119	422.00
IUUC-Dno-028855	Dasypus novemcinctus	56.02	0.00e+00	777.00
IUUC-Dor-030475	Dipodomys ordii	58.92	1.00e-133	471.00
IUUC-Eca-034147	Equus caballus	58.32	0.00e+00	834.00
IUUC-Fca-036550	Felis catus	44.82	0.00e+00	658.00
IUUC-Gac-042087	Gasterosteus aculeatus	60.81	0.00e+00	1145.00
IUUC-Ggo-045171	Gorilla gorilla	49.82	0.00e+00	880.00
IUUC-Hsa-045961	Homo sapiens	49.73	0.00e+00	879.00
IUUC-Lch-050332	Latimeria chalumnae	46.93	0.00e+00	657.00
IUUC-Loc-052852	Lepisosteus oculatus	63.67	0.00e+00	1323.00
IUUC-Laf-054033	Loxodonta africana	48.31	0.00e+00	838.00
IUUC-Mcc-055431	Macaca mulatta	50.09	0.00e+00	884.00
IUUC-Mmr-061035	Microcebus murinus	48.16	0.00e+00	865.00
IUUC-Mdo-062172	Monodelphis domestica	53.36	0.00e+00	767.00
IUUC-Mmu-063966	Mus musculus	57.48	0.00e+00	832.00
IUUC-Mpu-066307	Mustela putorius furo	46.38	0.00e+00	786.00
IUUC-Nle-070172	Nomascus leucogenys	49.64	0.00e+00	874.00
IUUC-Opr-070499	Ochotona princeps	57.06	0.00e+00	731.00
IUUC-Ont-071920	Oreochromis niloticus	61.06	0.00e+00	1201.00
IUUC-Ocu-074014	Oryctolagus cuniculus	56.16	0.00e+00	726.00
IUUC-Ola-086360	Oryzias latipes	61.02	0.00e+00	1140.00
IUUC-Oga-088202	Otolemur garnettii	48.81	0.00e+00	851.00
IUUC-Oar-089819	Ovis aries	48.84	0.00e+00	824.00
IUUC-Ptr-091076	Pan troglodytes	49.82	0.00e+00	881.00
IUUC-Pan-092248	Papio anubis	49.73	0.00e+00	879.00
IUUC-Pfo-096534	Poecilia formosa	59.90	0.00e+00	1165.00
IUUC-Pab-098453	Pongo abelii	48.70	0.00e+00	822.00
IUUC-Pca-100290	Procavia capensis	44.65	7.00e-81	295.00
IUUC-Rno-104948	Rattus norvegicus	56.35	0.00e+00	758.00
IUUC-Sha-106558	Sarcophilus harrisii	47.66	0.00e+00	863.00
IUUC-Sar-113105	Sorex araneus	49.72	2.00e-171	596.00
IUUC-Ssc-115312	Sus scrofa	49.40	0.00e+00	862.00
IUUC-Tru-117995	Takifugu rubripes	59.71	0.00e+00	1136.00
IUUC-Tni-120517	Tetraodon nigroviridis	57.66	0.00e+00	1063.00
IUUC-Tbe-127439	Tupaia belangeri	34.66	4.00e-43	170.00
IUUC-Ttr-128829	Tursiops truncatus	44.27	0.00e+00	707.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence