iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Tru-117907

Ensembl Protein ID

ENSTRUP00000019604.1

UniProt Accession

H2T4L6; H2T4L6_TAKRU

Protein Name

Uncharacterized protein

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSTRUG00000007879.1	ENSTRUT00000019682.1	ENSTRUP00000019602.1
ENSTRUG00000007879.1	ENSTRUT00000019683.1	ENSTRUP00000019603.1
ENSTRUG00000007879.1	ENSTRUT00000019684.1	ENSTRUP00000019604.1
ENSTRUG00000007879.1	ENSTRUT00000019685.1	ENSTRUP00000019605.1
ENSTRUG00000007879.1	ENSTRUT00000019686.1	ENSTRUP00000019606.1
ENSTRUG00000007879.1	ENSTRUT00000019687.1	ENSTRUP00000019607.1
ENSTRUG00000007879.1	ENSTRUT00000019688.1	ENSTRUP00000019608.1
ENSTRUG00000007879.1	ENSTRUT00000019689.1	ENSTRUP00000019609.1
ENSTRUG00000007879.1	ENSTRUT00000019690.1	ENSTRUP00000019610.1
ENSTRUG00000007879.1	ENSTRUT00000019691.1	ENSTRUP00000019611.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
UBD/Alpha-Helix/UBA	8.30e-06	27.0	962	998

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

UBD/Alpha-Helix/UBA

   S: 5    dkleqlveMGF.dreealqaLraannnleaAveyLld 40
           +++eql + G  +r+e+ + L+++n+nle+ ++ +ld
   Q: 962  SQVEQLFSLGLrSRSECEELLQRCNWNLEESSTVVLD 998
           689***************************9998886 PP

Organism

Takifugu rubripes

Protein Sequence
(Fasta)

MQCEEGTEWL LELLTDVQLQ HYFLRIRDEL NVTRLSHFDY VKNEDLEKIG MGRPGDSAAL 60
EFLTCDCVGS GQRRLWEAIK RRRALYKRKS WMSKVFPVKR SDADPQQALP QGATASAVAA 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CAGAGGAGAG GAGGTGGGGG AGGAGGAGGA GGAGGAGGAG GCGAGAGACA GGAGGAGAGG 60
AGATGTCAGA GGAGGAATGG TAAAATGTGA ATTTGTGGTC CAACGTAACC TTTTCCTGTG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0297--G-protein coupled receptor
KW-0472--Membrane
KW-0675--Receptor
KW-1185--Reference proteome
KW-0807--Transducer
KW-0812--Transmembrane
KW-1133--Transmembrane helix

Interpro

IPR000276--GPCR_Rhodpsn
IPR017452--GPCR_Rhodpsn_7TM
IPR011009--Kinase-like_dom
IPR000719--Prot_kinase_dom
IPR001245--Ser-Thr/Tyr_kinase_cat_dom
IPR008266--Tyr_kinase_AS
IPR020635--Tyr_kinase_cat_dom

PROSITE

PS00237--G_PROTEIN_RECEP_F1_1
PS50262--G_PROTEIN_RECEP_F1_2
PS50011--PROTEIN_KINASE_DOM
PS00109--PROTEIN_KINASE_TYR

Pfam

PF00001--7tm_1
PF07714--Pkinase_Tyr

PRINTS

PR00237--GPCRRHODOPSN
PR00109--TYRKINASE

SMART

SM00219--TyrKc

Gene Ontology

GO:0031234--C:extrinsic component of cytoplasmic side of plasma membrane
GO:0016021--C:integral component of membrane
GO:0005524--F:ATP binding
GO:0004930--F:G-protein coupled receptor activity
GO:0004715--F:non-membrane spanning protein tyrosine kinase activity
GO:0005102--F:receptor binding
GO:0030154--P:cell differentiation
GO:0016477--P:cell migration
GO:0045087--P:innate immune response
GO:0038083--P:peptidyl-tyrosine autophosphorylation
GO:0042127--P:regulation of cell proliferation
GO:0007169--P:transmembrane receptor protein tyrosine kinase signaling pathway

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aca-004315	Anolis carolinensis	77.21	3.00e-65	240.00
IUUC-Ame-011350	Astyanax mexicanus	64.69	3.00e-180	626.00
IUUC-Csv-026328	Ciona savignyi	48.06	7.00e-125	440.00
IUUC-Dre-027807	Danio rerio	67.51	0.00e+00	652.00
IUUC-Dme-031778	Drosophila melanogaster	48.92	3.00e-123	436.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence