iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Aca-004870

Ensembl Protein ID

ENSACAP00000022481.1

UniProt Accession

R4GB16; R4GB16_ANOCA

Protein Name

Uncharacterized protein

Gene Name

WDR77

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSACAG00000028755.1	ENSACAT00000029898.1	ENSACAP00000022481.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	8.50e-19	66.9	147	178

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 2    Htdsvtclaf...sdtllvsGsdDgtikvWDl 30
           Ht+ vtc+a     dt ++s++ Dg+i +WD+
   Q: 147  HTGQVTCVAScagKDTVFLSCAEDGKILLWDT 178
           ********8449877****************7 PP

Organism

Anolis carolinensis

Protein Sequence
(Fasta)

IERASTLSRA LHSLPFSFAD GSLLLGASSL SGRCWVGSIW VFKDSSKAPN EGFCSAGVQT 60
EAGIADLKWV ADKGILVASD SGALELWELD ENETLIVNKF CKYEHDNIVT TVSVLPNNTQ 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

AAACGTCAGG AGGGAATGCT TCGAGAACAT GGCCATACAG CCCGGAAAAT GCACAACCCA 60
GTGATTCCGG CCATGAATGC CTTCGACAAC ACATATAAAA CAAAAAATTT GAACTCAGAA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0853--WD repeat

Interpro

IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF00400--WD40

SMART

SM00320--WD40

Gene Ontology

GO:0005829--C:cytosol
GO:0005794--C:Golgi apparatus
GO:0034709--C:methylosome
GO:0005654--C:nucleoplasm
GO:0030374--F:ligand-dependent nuclear receptor transcription coactivator activity
GO:0008327--F:methyl-CpG binding
GO:0060770--P:negative regulation of epithelial cell proliferation involved in prostate gland development
GO:0008284--P:positive regulation of cell proliferation
GO:0006357--P:regulation of transcription from RNA polymerase II promoter
GO:0060528--P:secretory columnal luminar epithelial cell differentiation involved in prostate glandular acinus development

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002192	Ailuropoda melanoleuca	69.29	6.00e-118	416.00
IUUC-Apl-003921	Anas platyrhynchos	72.58	7.00e-75	272.00
IUUC-Ame-011872	Astyanax mexicanus	47.80	1.00e-38	152.00
IUUC-Bta-013325	Bos taurus	70.61	2.00e-120	425.00
IUUC-Cja-019059	Callithrix jacchus	70.97	2.00e-120	424.00
IUUC-Cfa-021036	Canis familiaris	69.53	4.00e-119	421.00
IUUC-Cpo-022369	Cavia porcellus	69.53	8.00e-119	419.00
IUUC-Csa-023585	Chlorocebus sabaeus	70.97	3.00e-120	424.00
IUUC-Cho-024470	Choloepus hoffmanni	65.50	4.00e-86	310.00
IUUC-Dno-029867	Dasypus novemcinctus	68.75	5.00e-120	423.00
IUUC-Dor-030834	Dipodomys ordii	61.51	2.00e-78	285.00
IUUC-Ete-032245	Echinops telfairi	64.24	4.00e-108	384.00
IUUC-Eca-033360	Equus caballus	70.61	1.00e-115	409.00
IUUC-Eeu-035353	Erinaceus europaeus	68.82	1.00e-118	419.00
IUUC-Fca-036277	Felis catus	71.33	8.00e-122	429.00
IUUC-Fal-037383	Ficedula albicollis	74.90	9.00e-113	399.00
IUUC-Gmo-038575	Gadus morhua	57.09	8.00e-94	336.00
IUUC-Gga-040658	Gallus gallus	73.87	2.00e-128	451.00
IUUC-Gac-041463	Gasterosteus aculeatus	51.60	2.00e-82	298.00
IUUC-Ggo-045120	Gorilla gorilla	70.00	3.00e-119	421.00
IUUC-Hsa-046247	Homo sapiens	70.25	4.00e-119	420.00
IUUC-Itr-048292	Ictidomys tridecemlineatus	71.33	2.00e-117	415.00
IUUC-Lch-049741	Latimeria chalumnae	66.67	2.00e-100	358.00
IUUC-Loc-052695	Lepisosteus oculatus	59.21	1.00e-96	346.00
IUUC-Laf-054535	Loxodonta africana	68.03	3.00e-119	421.00
IUUC-Mcc-054699	Macaca mulatta	70.97	3.00e-120	424.00
IUUC-Meu-056053	Macropus eugenii	65.92	1.00e-106	379.00
IUUC-Mga-059672	Meleagris gallopavo	73.82	2.00e-81	294.00
IUUC-Mmr-060963	Microcebus murinus	70.61	5.00e-120	423.00
IUUC-Mdo-062694	Monodelphis domestica	63.50	7.00e-102	363.00
IUUC-Mmu-064031	Mus musculus	69.31	3.00e-121	427.00
IUUC-Mpu-066408	Mustela putorius furo	70.61	4.00e-121	427.00
IUUC-Mlu-068184	Myotis lucifugus	69.90	4.00e-121	427.00
IUUC-Nle-069251	Nomascus leucogenys	70.97	1.00e-120	426.00
IUUC-Opr-071156	Ochotona princeps	63.89	2.00e-109	389.00
IUUC-Ont-072683	Oreochromis niloticus	56.00	1.00e-90	326.00
IUUC-Oan-073042	Ornithorhynchus anatinus	66.06	7.00e-107	379.00
IUUC-Ocu-074843	Oryctolagus cuniculus	70.00	4.00e-119	421.00
IUUC-Ola-086929	Oryzias latipes	50.90	1.00e-80	293.00
IUUC-Oga-088237	Otolemur garnettii	71.33	8.00e-121	426.00
IUUC-Oar-089312	Ovis aries	70.61	8.00e-121	426.00
IUUC-Ptr-091625	Pan troglodytes	69.89	1.00e-118	419.00
IUUC-Pan-091902	Papio anubis	70.97	3.00e-120	424.00
IUUC-Psi-094035	Pelodiscus sinensis	77.21	5.00e-137	479.00
IUUC-Pma-094565	Petromyzon marinus	57.54	3.00e-45	174.00
IUUC-Pfo-097070	Poecilia formosa	52.35	2.00e-88	318.00
IUUC-Pab-098007	Pongo abelii	70.61	2.00e-119	422.00
IUUC-Pca-100513	Procavia capensis	52.56	4.00e-61	227.00
IUUC-Pva-102821	Pteropus vampyrus	62.85	5.00e-107	380.00
IUUC-Rno-105836	Rattus norvegicus	69.82	7.00e-119	419.00
IUUC-Sha-106847	Sarcophilus harrisii	60.50	9.00e-73	266.00
IUUC-Sar-113451	Sorex araneus	64.93	7.00e-117	413.00
IUUC-Ssc-115978	Sus scrofa	70.25	8.00e-117	413.00
IUUC-Tgu-116745	Taeniopygia guttata	77.63	6.00e-106	375.00
IUUC-Tru-117945	Takifugu rubripes	51.56	2.00e-77	281.00
IUUC-Tsy-119059	Tarsius syrichta	65.45	1.00e-61	228.00
IUUC-Tni-120414	Tetraodon nigroviridis	54.12	1.00e-89	322.00
IUUC-Tbe-127559	Tupaia belangeri	71.33	2.00e-121	428.00
IUUC-Ttr-128505	Tursiops truncatus	66.67	3.00e-115	407.00
IUUC-Vpa-130350	Vicugna pacos	71.98	3.00e-80	290.00
IUUC-Xtr-132939	Xenopus tropicalis	62.99	1.00e-107	382.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence