iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Xma-133119

Ensembl Protein ID

ENSXMAP00000010573.1

UniProt Accession

M4A7X9; M4A7X9_XIPMA

Genbank Protein ID

ENSXMAP00000010573

Protein Name

Histone-lysine N-methyltransferase

Genbank Nucleotide ID

AGAJ01006172

Gene Name

KMT2B

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSXMAG00000010541.1	ENSXMAT00000010587.1	ENSXMAP00000010573.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/RING/PHD	3.30e-21	75.3	871	929

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 activity/RING/PHD

   S: 2    kvClvCgeggedek...slveCekCrewfHpaClkls.....veeelpnsekwiCpkCr 52
           ++C++C++++ed++   ++++C  C++w+H++C  l+     + ++lp+s  + C+ C+
   Q: 871  NYCPICFKCYEDNDydsQMMQCGSCNHWVHAKCEDLTdelyeILSSLPESVVYSCRPCS 929
           79**********98888*****************************************7 PP

Organism

Xiphophorus maculatus

Protein Sequence
(Fasta)

PSQVSTEESA PQILPINSCP NLVEDPPQVT SLNCSEVLEK ESPKAADTPS QTADEIEMGM 60
EKDSLNVQPC KSKFVKNIKH FIMPVVSARS SRVIKTPQRF MDDVGMSVLP RRHSPKKGLQ 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CCCTCTCAGG TTTCAACTGA GGAGTCTGCT CCTCAAATTC TTCCAATAAA CTCATGTCCT 60
AATTTAGTTG AAGACCCACC ACAGGTGACC AGTTTAAACT GTTCCGAAGT TCTTGAAAAG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0479--Metal-binding
KW-0489--Methyltransferase
KW-0539--Nucleus
KW-1185--Reference proteome
KW-0949--S-adenosyl-L-methionine
KW-0808--Transferase
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR034732--EPHD
IPR003889--FYrich_C
IPR003888--FYrich_N
IPR003616--Post-SET_dom
IPR001214--SET_dom
IPR002857--Znf_CXXC
IPR011011--Znf_FYVE_PHD
IPR001965--Znf_PHD
IPR019787--Znf_PHD-finger
IPR013083--Znf_RING/FYVE/PHD

PROSITE

PS51805--EPHD
PS51543--FYRC
PS51542--FYRN
PS50868--POST_SET
PS50280--SET
PS51058--ZF_CXXC
PS50016--ZF_PHD_2

Pfam

PF05965--FYRC
PF05964--FYRN
PF00628--PHD
PF00856--SET
PF02008--zf-CXXC

SMART

SM00542--FYRC
SM00541--FYRN
SM00249--PHD
SM00317--SET

Gene Ontology

GO:0005634--C:nucleus
GO:0003677--F:DNA binding
GO:0018024--F:histone-lysine N-methyltransferase activity
GO:0008270--F:zinc ion binding

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002367	Ailuropoda melanoleuca	46.37	0.00e+00	917.00
IUUC-Atr-002455	Amborella trichopoda	39.92	2.00e-40	160.00
IUUC-Apl-003478	Anas platyrhynchos	47.92	0.00e+00	772.00
IUUC-Aca-004718	Anolis carolinensis	42.90	0.00e+00	1026.00
IUUC-Ame-010705	Astyanax mexicanus	51.33	0.00e+00	1477.00
IUUC-Bta-013578	Bos taurus	47.74	0.00e+00	917.00
IUUC-Cja-019138	Callithrix jacchus	47.50	0.00e+00	902.00
IUUC-Cfa-020020	Canis familiaris	47.07	0.00e+00	895.00
IUUC-Cpo-021552	Cavia porcellus	45.14	0.00e+00	887.00
IUUC-Csa-024216	Chlorocebus sabaeus	47.68	0.00e+00	909.00
IUUC-Cin-025724	Ciona intestinalis	51.68	1.00e-94	342.00
IUUC-Csv-026268	Ciona savignyi	36.02	2.00e-125	444.00
IUUC-Dre-027440	Danio rerio	53.95	0.00e+00	1532.00
IUUC-Dno-029583	Dasypus novemcinctus	46.13	0.00e+00	929.00
IUUC-Dor-030903	Dipodomys ordii	45.57	0.00e+00	916.00
IUUC-Eca-034026	Equus caballus	49.43	0.00e+00	856.00
IUUC-Eeu-034687	Erinaceus europaeus	65.76	7.00e-150	526.00
IUUC-Fca-036311	Felis catus	46.45	0.00e+00	921.00
IUUC-Gmo-039265	Gadus morhua	55.69	0.00e+00	1362.00
IUUC-Gac-042202	Gasterosteus aculeatus	75.28	0.00e+00	1350.00
IUUC-Ggo-044791	Gorilla gorilla	49.06	0.00e+00	876.00
IUUC-Hsa-046988	Homo sapiens	47.08	0.00e+00	897.00
IUUC-Itr-048907	Ictidomys tridecemlineatus	47.30	0.00e+00	936.00
IUUC-Loc-052252	Lepisosteus oculatus	67.89	0.00e+00	1151.00
IUUC-Laf-053703	Loxodonta africana	47.95	0.00e+00	924.00
IUUC-Mcc-054782	Macaca mulatta	47.16	0.00e+00	900.00
IUUC-Meu-056046	Macropus eugenii	46.88	0.00e+00	912.00
IUUC-Mmr-061316	Microcebus murinus	45.99	0.00e+00	877.00
IUUC-Mdo-062648	Monodelphis domestica	44.84	0.00e+00	925.00
IUUC-Mmu-063579	Mus musculus	46.65	0.00e+00	935.00
IUUC-Mpu-066710	Mustela putorius furo	47.66	0.00e+00	915.00
IUUC-Mlu-067559	Myotis lucifugus	46.82	0.00e+00	911.00
IUUC-Nle-070085	Nomascus leucogenys	47.41	0.00e+00	889.00
IUUC-Opr-071148	Ochotona princeps	46.26	0.00e+00	902.00
IUUC-Ont-071626	Oreochromis niloticus	68.49	0.00e+00	1750.00
IUUC-Ocu-074475	Oryctolagus cuniculus	47.42	0.00e+00	890.00
IUUC-Obr-076458	Oryza brachyantha	33.66	3.00e-24	107.00
IUUC-Oin-079802	Oryza indica	28.70	4.00e-20	93.20
IUUC-Ola-086609	Oryzias latipes	66.04	0.00e+00	1433.00
IUUC-Oga-088140	Otolemur garnettii	47.04	0.00e+00	902.00
IUUC-Oar-089447	Ovis aries	47.83	0.00e+00	929.00
IUUC-Ptr-090902	Pan troglodytes	47.08	0.00e+00	897.00
IUUC-Pan-091930	Papio anubis	47.59	0.00e+00	907.00
IUUC-Ppa-095221	Physcomitrella patens	35.44	8.00e-29	122.00
IUUC-Pfo-096884	Poecilia formosa	81.41	0.00e+00	2365.00
IUUC-Pva-102634	Pteropus vampyrus	45.75	0.00e+00	909.00
IUUC-Rno-105870	Rattus norvegicus	46.59	0.00e+00	932.00
IUUC-Sar-113289	Sorex araneus	41.65	0.00e+00	686.00
IUUC-Ssc-115509	Sus scrofa	47.68	0.00e+00	919.00
IUUC-Tni-119794	Tetraodon nigroviridis	68.31	0.00e+00	841.00
IUUC-Tbe-127825	Tupaia belangeri	42.91	2.00e-151	531.00
IUUC-Ttr-128754	Tursiops truncatus	42.95	2.00e-149	524.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence