iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSBTAG00000004783.5	ENSBTAT00000029972.4	ENSBTAP00000029960.4
ENSBTAG00000004783.5	ENSBTAT00000006281.5	ENSBTAP00000006281.5

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	5.50e-16	58.2	79	111

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 1    gHtdsvtclaf...sdtllvsGsdDgtikvWDl 30
           gHt++v ++++   +d  ++sGs D+t++vW +
   Q: 79   GHTGPVLDIDWcphNDEVIASGSEDCTVMVWQI 111
           8***********977799*************75 PP

Organism

Bos taurus

Protein Sequence
(Fasta)

MFRKVVRQSK FRHVFGQPVK NDQCYEDIRV SRVTWDSTFC AVNPKFLAVI VEASGGGAFL 60
VLPLSKTGRI DKAYPTVCGH TGPVLDIDWC PHNDEVIASG SEDCTVMVWQ IPENGLVSPL 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GCTTCCTGCT TCCCAGAGAC TGGGATCCAG AGCCACCCGA GGACGAGGAC GGTGCTGCAG 60
CCTCTCGGCG TCCCTGGTGA GCACGATGGA TTGGGGCTGG GGGCGCGGGC GTAGGGGTTG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-1267--Proteomics identification
KW-1185--Reference proteome
KW-0677--Repeat
KW-0853--WD repeat

Interpro

IPR015505--Coronin
IPR015048--DUF1899
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF08953--DUF1899
PF00400--WD40

SMART

SM01166--DUF1899
SM00320--WD40

Gene Ontology

GO:0015629--C:actin cytoskeleton
GO:0005884--C:actin filament
GO:0005829--C:cytosol
GO:0070062--C:extracellular exosome
GO:0005925--C:focal adhesion
GO:0030027--C:lamellipodium
GO:0048471--C:perinuclear region of cytoplasm
GO:0005886--C:plasma membrane
GO:0001725--C:stress fiber
GO:0051015--F:actin filament binding
GO:0030036--P:actin cytoskeleton organization
GO:0090135--P:actin filament branching
GO:0051017--P:actin filament bundle assembly
GO:0036120--P:cellular response to platelet-derived growth factor stimulus
GO:0035767--P:endothelial cell chemotaxis
GO:0034316--P:negative regulation of Arp2/3 complex-mediated actin nucleation
GO:0071672--P:negative regulation of smooth muscle cell chemotaxis
GO:2000394--P:positive regulation of lamellipodium morphogenesis
GO:1902463--P:protein localization to cell leading edge
GO:0031529--P:ruffle organization
GO:0042060--P:wound healing

KEGG

bta:510128

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002423	Ailuropoda melanoleuca	92.61	0.00e+00	939.00
IUUC-Aca-005056	Anolis carolinensis	80.94	0.00e+00	822.00
IUUC-Cja-019498	Callithrix jacchus	91.39	0.00e+00	918.00
IUUC-Cfa-020937	Canis familiaris	94.76	0.00e+00	873.00
IUUC-Cpo-021866	Cavia porcellus	88.50	0.00e+00	883.00
IUUC-Csa-023561	Chlorocebus sabaeus	91.99	0.00e+00	934.00
IUUC-Dno-029770	Dasypus novemcinctus	87.12	0.00e+00	865.00
IUUC-Dor-030989	Dipodomys ordii	91.58	0.00e+00	904.00
IUUC-Eca-033901	Equus caballus	93.84	0.00e+00	919.00
IUUC-Fca-036494	Felis catus	93.43	0.00e+00	901.00
IUUC-Fal-036737	Ficedula albicollis	83.74	0.00e+00	837.00
IUUC-Ggo-045035	Gorilla gorilla	92.40	0.00e+00	932.00
IUUC-Hsa-046154	Homo sapiens	91.99	0.00e+00	927.00
IUUC-Itr-048847	Ictidomys tridecemlineatus	90.76	0.00e+00	893.00
IUUC-Laf-054566	Loxodonta africana	91.58	0.00e+00	885.00
IUUC-Mcc-054879	Macaca mulatta	92.20	0.00e+00	931.00
IUUC-Mmr-060910	Microcebus murinus	92.40	0.00e+00	930.00
IUUC-Mmu-063455	Mus musculus	92.18	0.00e+00	931.00
IUUC-Mpu-066350	Mustela putorius furo	93.43	0.00e+00	922.00
IUUC-Mlu-067353	Myotis lucifugus	93.60	0.00e+00	922.00
IUUC-Nle-069161	Nomascus leucogenys	92.20	0.00e+00	925.00
IUUC-Opr-071106	Ochotona princeps	90.76	0.00e+00	895.00
IUUC-Oga-088805	Otolemur garnettii	91.80	0.00e+00	934.00
IUUC-Oar-090373	Ovis aries	80.57	0.00e+00	785.00
IUUC-Ptr-091484	Pan troglodytes	91.99	0.00e+00	928.00
IUUC-Pan-091843	Papio anubis	91.58	0.00e+00	922.00
IUUC-Pab-097835	Pongo abelii	92.40	0.00e+00	931.00
IUUC-Pca-100411	Procavia capensis	80.29	0.00e+00	791.00
IUUC-Pva-102659	Pteropus vampyrus	93.63	0.00e+00	927.00
IUUC-Rno-106070	Rattus norvegicus	92.18	0.00e+00	929.00
IUUC-Sha-106609	Sarcophilus harrisii	94.05	0.00e+00	712.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence