iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Mdo-063007

Ensembl Protein ID

ENSMODP00000017708.3

UniProt Accession

F6UN22; F6UN22_MONDO

Protein Name

Uncharacterized protein

Gene Name

WDR62

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSMODG00000014161.4	ENSMODT00000018036.3	ENSMODP00000017708.3

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	8.70e-29	98.5	159	197
UBD/Beta-Prp	1.20e-55	188.9	497	756

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 1    gHtdsvtclaf.sd.tllvsGs..dDgtikvWDlrtgvl 35
           gH+ +v c+af ++ +++vs +  +D ++ vWD++++ +
   Q: 159  GHKYGVACVAFsPNmKHIVSMGyqHDMVVNVWDWKKDSV 197
           89**********888*****9989*********998766 PP

UBD/Beta-Prp

   S: 9    hksvitcvkfspdksllatgsrdgtikvwdvttgkllrslsgheaevtavkfspdgk...ilvtgseDrtikvwdls.tgkcvhtlkgh 93
           +ks ++++++spd+++la+g r+g +++++++ ++ l +++ h+aev ++++s+ +    +l+++s+Dr+i+v +++ ++   +tl  h
   Q: 497  MKSGVRVMQVSPDGQHLASGDRSGNLRIHELRFMDELIKVEAHDAEVLCLEYSKPETgmtLLASASRDRLIHVLNVEkNYNLEQTLDDH 585
           7888999*********************************************99887899***************997888999***** PP
   S: 94   edsvlslsfspsg.dklvsGshdrtirvwdletgqclee.......tlsghdgvvncvvvhpdgnllvsGslDrtvrlWdl...ktgkl 171
           ++s+++++f  ++   ++s ++d+ i     ++ q++++           ++ +   + ++ ++++++ ++ Dr vr+++    k++k+
   Q: 586  SSSITAIKFAGNRdIQMISCGADKSIY---FRSAQKVSDglhfvrtHHVAEKTTLYDMDIDITQKYVAVACQDRNVRVYNTvngKQKKC 671
           ***********885789*******985...4677777777777443222223334456778888****************988888888 PP
   S: 172  lrtltgghtdsvyslsfdsngkelvsgsldgtvklwdlqtgecvrtlnghtdnvksvrfspnderlvsgssDgsiriW.......d 250
            +  +g +++s  ++ +d++g++l++   d+++ + d+ +gec+ ++ gh++ v+ ++f+ +  +l+++s D  ++iW       +
   Q: 672  YKGSQG-DDGSLLKVHVDPSGTFLATSCSDKSISVIDFYSGECIAKMFGHSEIVTGMKFTYDCRHLITVSGDSCVFIWqlgpeitN 756
           888898.999999999**************************************************************55443333 PP

Organism

Monodelphis domestica

Protein Sequence
(Fasta)

MAALEPGVGG YGRSEAGTRG EKEKQPGPVS SRRTLVSPPP PPPPPLCLKR RLKLLPGPEE 60
TVQSRVTLEK VLGITAQNSS GLTCDPNTGY IAYLAGCVVV VLDPKKSKQQ HIFNTARKAL 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

AACAAAAAAA GGTGGGGGAG GTGCTACAAA CATAGAAAGT TTCCGAAGAG GTTCACACTC 60
GAACCCCAGA CAATGTTATT CCGGAGAGCA CCACTCTCCT CGTGGCACCA CCCTGCGCTA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0677--Repeat
KW-0853--WD repeat

Interpro

IPR024977--Apc4_WD40_dom
IPR011047--Quinoprotein_ADH-like_supfam
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR017986--WD40_repeat_dom
IPR030545--WDR62

PROSITE

PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF12894--ANAPC4_WD40
PF00400--WD40

SMART

SM00320--WD40

Gene Ontology

GO:0071013--C:catalytic step 2 spliceosome
GO:0005813--C:centrosome
GO:0071011--C:precatalytic spliceosome
GO:0000922--C:spindle pole
GO:0005682--C:U5 snRNP
GO:0007099--P:centriole replication
GO:0021987--P:cerebral cortex development
GO:0007052--P:mitotic spindle organization
GO:0022008--P:neurogenesis
GO:0008380--P:RNA splicing

KEGG

mdo:100016939

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001371	Ailuropoda melanoleuca	63.13	0.00e+00	1816.00
IUUC-Atr-003165	Amborella trichopoda	34.33	4.00e-122	432.00
IUUC-Aca-004935	Anolis carolinensis	72.94	0.00e+00	1041.00
IUUC-Ath-007624	Arabidopsis thaliana	30.57	6.00e-90	325.00
IUUC-Acl-008257	Aspergillus clavatus	22.06	1.00e-26	115.00
IUUC-Afl-008426	Aspergillus flavus	22.63	2.00e-28	121.00
IUUC-Afu-008757	Aspergillus fumigatus	21.57	2.00e-32	134.00
IUUC-Ate-010425	Aspergillus terreus	22.97	2.00e-25	111.00
IUUC-Ame-010799	Astyanax mexicanus	56.90	0.00e+00	984.00
IUUC-Bta-013336	Bos taurus	63.37	0.00e+00	1769.00
IUUC-Bci-013828	Botrytis cinerea	23.66	8.00e-36	145.00
IUUC-Bol-016347	Brassica oleracea	29.99	1.00e-84	308.00
IUUC-Bra-017959	Brassica rapa	30.88	1.00e-87	318.00
IUUC-Cel-018592	Caenorhabditis elegans	28.90	9.00e-74	272.00
IUUC-Cja-019094	Callithrix jacchus	64.67	0.00e+00	1752.00
IUUC-Cfa-020529	Canis familiaris	64.65	0.00e+00	1835.00
IUUC-Cpo-021970	Cavia porcellus	76.57	0.00e+00	1464.00
IUUC-Cre-022999	Chlamydomonas reinhardtii	27.03	1.00e-12	68.60
IUUC-Csa-024161	Chlorocebus sabaeus	64.18	0.00e+00	1679.00
IUUC-Cho-024310	Choloepus hoffmanni	76.70	0.00e+00	1043.00
IUUC-Cin-025412	Ciona intestinalis	55.17	6.00e-58	216.00
IUUC-Csv-026079	Ciona savignyi	42.45	7.00e-82	297.00
IUUC-Cgl-026454	Colletotrichum gloeosporioides	24.21	9.00e-27	115.00
IUUC-Dre-028678	Danio rerio	53.55	0.00e+00	1013.00
IUUC-Dno-029933	Dasypus novemcinctus	60.65	0.00e+00	1665.00
IUUC-Dor-031147	Dipodomys ordii	62.20	0.00e+00	1695.00
IUUC-Dse-031501	Dothistroma septosporum	26.67	5.00e-24	107.00
IUUC-Dme-032179	Drosophila melanogaster	49.37	0.00e+00	747.00
IUUC-Eca-033675	Equus caballus	76.96	0.00e+00	1660.00
IUUC-Fca-035826	Felis catus	64.35	0.00e+00	1852.00
IUUC-Fox-037952	Fusarium oxysporum	21.75	2.00e-27	117.00
IUUC-Fso-038440	Fusarium solani	23.18	3.00e-34	140.00
IUUC-Gmo-039644	Gadus morhua	54.01	0.00e+00	732.00
IUUC-Ggr-039729	Gaeumannomyces graminis	23.22	2.00e-26	115.00
IUUC-Gma-043644	Glycine max	31.15	6.00e-99	355.00
IUUC-Ggo-045152	Gorilla gorilla	64.54	0.00e+00	1724.00
IUUC-Hsa-045891	Homo sapiens	63.62	0.00e+00	1705.00
IUUC-Itr-048019	Ictidomys tridecemlineatus	87.86	0.00e+00	1443.00
IUUC-Lch-049669	Latimeria chalumnae	50.00	0.00e+00	1165.00
IUUC-Loc-052488	Lepisosteus oculatus	55.15	0.00e+00	1025.00
IUUC-Laf-053992	Loxodonta africana	63.01	0.00e+00	1803.00
IUUC-Mcc-054994	Macaca mulatta	65.33	0.00e+00	1722.00
IUUC-Meu-056815	Macropus eugenii	89.76	0.00e+00	1615.00
IUUC-Mtr-058383	Medicago truncatula	30.87	4.00e-50	192.00
IUUC-Mmr-060693	Microcebus murinus	63.17	0.00e+00	1776.00
IUUC-Mmu-064067	Mus musculus	61.36	0.00e+00	1726.00
IUUC-Mpu-066532	Mustela putorius furo	64.42	0.00e+00	1872.00
IUUC-Mlu-066982	Myotis lucifugus	63.20	0.00e+00	1761.00
IUUC-Nfi-068613	Neosartorya fischeri	22.30	3.00e-32	134.00
IUUC-Ncr-068758	Neurospora crassa	21.96	4.00e-28	120.00
IUUC-Nle-070042	Nomascus leucogenys	70.80	0.00e+00	1626.00
IUUC-Opr-070397	Ochotona princeps	62.07	0.00e+00	1779.00
IUUC-Oan-073119	Ornithorhynchus anatinus	67.88	0.00e+00	890.00
IUUC-Ocu-074274	Oryctolagus cuniculus	63.21	0.00e+00	1734.00
IUUC-Oga-088577	Otolemur garnettii	63.02	0.00e+00	1777.00
IUUC-Oar-090117	Ovis aries	61.61	0.00e+00	1691.00
IUUC-Ptr-090553	Pan troglodytes	63.88	0.00e+00	1722.00
IUUC-Psi-093710	Pelodiscus sinensis	66.48	0.00e+00	1457.00
IUUC-Pma-094285	Petromyzon marinus	60.56	0.00e+00	940.00
IUUC-Ppa-095596	Physcomitrella patens	36.27	1.00e-134	475.00
IUUC-Pab-098510	Pongo abelii	65.30	0.00e+00	1718.00
IUUC-Pop-099155	Populus trichocarpa	32.13	1.00e-97	352.00
IUUC-Pca-100323	Procavia capensis	61.27	0.00e+00	1145.00
IUUC-Pva-102895	Pteropus vampyrus	64.94	0.00e+00	1841.00
IUUC-Pte-104373	Pyrenophora teres	24.93	2.00e-28	121.00
IUUC-Pyt-104804	Pyrenophora triticirepentis	24.79	3.00e-26	114.00
IUUC-Rno-105598	Rattus norvegicus	63.04	0.00e+00	1743.00
IUUC-Sha-107013	Sarcophilus harrisii	81.72	0.00e+00	2284.00
IUUC-Ssl-108471	Sclerotinia sclerotiorum	22.37	6.00e-30	126.00
IUUC-Smo-109134	Selaginella moellendorffii	36.36	1.00e-132	468.00
IUUC-Sly-110969	Solanum lycopersicum	29.52	1.00e-88	321.00
IUUC-Sar-113261	Sorex araneus	61.90	0.00e+00	1724.00
IUUC-Ssc-115317	Sus scrofa	63.70	0.00e+00	1737.00
IUUC-Tsy-118799	Tarsius syrichta	83.15	0.00e+00	797.00
IUUC-Tni-120316	Tetraodon nigroviridis	55.18	0.00e+00	778.00
IUUC-Tca-121475	Theobroma cacao	30.66	5.00e-94	339.00
IUUC-Tre-122008	Trichoderma reesei	23.56	3.00e-32	134.00
IUUC-Tvi-122281	Trichoderma virens	24.00	6.00e-32	133.00
IUUC-Tme-127128	Tuber melanosporum	25.07	1.00e-31	132.00
IUUC-Tbe-127555	Tupaia belangeri	86.87	0.00e+00	926.00
IUUC-Ttr-128722	Tursiops truncatus	61.02	0.00e+00	1715.00
IUUC-Vda-129957	Verticillium dahliae	24.53	4.00e-32	133.00
IUUC-Vpa-130392	Vicugna pacos	88.75	2.00e-78	287.00
IUUC-Vvi-131035	Vitis vinifera	33.24	1.00e-103	370.00
IUUC-Xtr-131789	Xenopus tropicalis	60.47	0.00e+00	998.00
IUUC-Xma-134011	Xiphophorus maculatus	59.35	0.00e+00	865.00
IUUC-Yli-134437	Yarrowia lipolytica	27.24	2.00e-17	84.70

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence