iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Tru-118738

UUCD1 version

UUC-TaR-00667

Ensembl Protein ID

ENSTRUP00000031574.1

UniProt Accession

H2U3R3; H2U3R3_TAKRU

Protein Name

Uncharacterized protein

Gene Name

KLHL28

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSTRUG00000012464.1	ENSTRUT00000031697.1	ENSTRUP00000031574.1
ENSTRUG00000012464.1	ENSTRUT00000031698.1	ENSTRUP00000031575.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/BCR/BTB_3-box: BTB	7.00e-18	66.0	41	104
E3 adaptor/Cullin RING/BCR/BTB_3-box: 3-box	2.40e-10	39.6	142	171

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/BCR/BTB_3-box: BTB

   S: 1    aDvilvvggeeffahkivLaasSsvFyalflmeleesksklmveikdvqpevfrallkFlYtgkl 65
           +D++l vg+ +++ahk+vLa+ S++F+a+f+++++e++ +++ve++ ++ ++++a++++ Ytg++
   Q: 41   CDIVLRVGDAKIHAHKVVLASISPYFKAMFTGNMSEKE-TSEVEFQCIDETALQAIVEYAYTGTV 104
           8***********************************97.************************87 PP

E3 adaptor/Cullin RING/BCR/BTB_3-box: 3-box

   S: 3    NclgilrfAdlydcpdLkdaaldfilkhFk 32
           Nc+gi rfA++y+c+dL++aa +fi+ +F+
   Q: 142  NCIGISRFAETYGCHDLCLAASKFICENFE 171
           ****************************95 PP

Organism

Takifugu rubripes

Protein Sequence
(Fasta)

LSSCFQMDQP DQSYMFASLK RPHSEQLLQG LQLLRQDHEL CDIVLRVGDA KIHAHKVVLA 60
SISPYFKAMF TGNMSEKETS EVEFQCIDET ALQAIVEYAY TGTVLITQET VESLLPAANL 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

TTGTCTTCCT GTTTTCAGAT GGACCAGCCA GACCAATCCT ATATGTTTGC TAGTCTAAAA 60
CGGCCTCATT CAGAACAGCT GCTGCAAGGT CTCCAGCTCC TGCGGCAGGA CCATGAACTA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0880--Kelch repeat
KW-1185--Reference proteome
KW-0677--Repeat

Interpro

IPR011705--BACK
IPR017096--BTB-kelch_protein
IPR000210--BTB/POZ_dom
IPR011043--Gal_Oxase/kelch_b-propeller
IPR015916--Gal_Oxidase_b-propeller
IPR015915--Kelch-typ_b-propeller
IPR006652--Kelch_1
IPR030569--KLHL28
IPR011333--SKP1/BTB/POZ

PROSITE

PS50097--BTB

Pfam

PF07707--BACK
PF00651--BTB
PF01344--Kelch_1

SMART

SM00875--BACK
SM00225--BTB
SM00612--Kelch

Gene Ontology

GO:0031463--C:Cul3-RING ubiquitin ligase complex
GO:0016567--P:protein ubiquitination

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001581	Ailuropoda melanoleuca	81.63	0.00e+00	984.00
IUUC-Apl-003577	Anas platyrhynchos	84.26	0.00e+00	983.00
IUUC-Aca-004320	Anolis carolinensis	82.44	0.00e+00	854.00
IUUC-Ame-011433	Astyanax mexicanus	92.70	0.00e+00	1062.00
IUUC-Bta-012650	Bos taurus	81.91	0.00e+00	983.00
IUUC-Cja-019878	Callithrix jacchus	81.42	0.00e+00	983.00
IUUC-Cfa-020936	Canis familiaris	82.09	0.00e+00	983.00
IUUC-Cpo-022212	Cavia porcellus	81.39	0.00e+00	972.00
IUUC-Csa-023372	Chlorocebus sabaeus	81.74	0.00e+00	982.00
IUUC-Cho-024885	Choloepus hoffmanni	85.27	5.00e-141	494.00
IUUC-Dno-029895	Dasypus novemcinctus	81.74	0.00e+00	980.00
IUUC-Ete-032703	Echinops telfairi	81.21	0.00e+00	758.00
IUUC-Eca-034150	Equus caballus	81.74	0.00e+00	981.00
IUUC-Eeu-035233	Erinaceus europaeus	79.83	0.00e+00	958.00
IUUC-Fca-036445	Felis catus	82.09	0.00e+00	981.00
IUUC-Fal-037156	Ficedula albicollis	76.70	0.00e+00	906.00
IUUC-Gmo-039158	Gadus morhua	93.57	0.00e+00	1095.00
IUUC-Gga-040855	Gallus gallus	83.13	0.00e+00	997.00
IUUC-Gac-041294	Gasterosteus aculeatus	95.13	0.00e+00	1113.00
IUUC-Ggo-045399	Gorilla gorilla	81.46	0.00e+00	984.00
IUUC-Hsa-046199	Homo sapiens	81.46	0.00e+00	984.00
IUUC-Itr-048859	Ictidomys tridecemlineatus	81.39	0.00e+00	978.00
IUUC-Lch-049445	Latimeria chalumnae	84.34	0.00e+00	762.00
IUUC-Loc-052737	Lepisosteus oculatus	89.91	0.00e+00	1051.00
IUUC-Laf-054173	Loxodonta africana	81.42	0.00e+00	971.00
IUUC-Mcc-055000	Macaca mulatta	81.35	0.00e+00	984.00
IUUC-Meu-056028	Macropus eugenii	87.75	2.00e-133	469.00
IUUC-Mga-059609	Meleagris gallopavo	83.02	0.00e+00	995.00
IUUC-Mmr-060842	Microcebus murinus	81.74	0.00e+00	982.00
IUUC-Mdo-062776	Monodelphis domestica	82.81	0.00e+00	964.00
IUUC-Mmu-063720	Mus musculus	81.22	0.00e+00	977.00
IUUC-Mpu-066594	Mustela putorius furo	56.28	7.00e-167	580.00
IUUC-Mlu-067403	Myotis lucifugus	81.04	0.00e+00	969.00
IUUC-Nle-069242	Nomascus leucogenys	81.22	0.00e+00	975.00
IUUC-Opr-070942	Ochotona princeps	83.61	4.00e-142	497.00
IUUC-Ont-072586	Oreochromis niloticus	95.16	0.00e+00	1120.00
IUUC-Oan-073070	Ornithorhynchus anatinus	84.93	0.00e+00	982.00
IUUC-Ocu-074536	Oryctolagus cuniculus	81.08	0.00e+00	973.00
IUUC-Ola-086669	Oryzias latipes	77.53	0.00e+00	881.00
IUUC-Oga-088974	Otolemur garnettii	81.39	0.00e+00	979.00
IUUC-Oar-089544	Ovis aries	81.07	0.00e+00	983.00
IUUC-Ptr-091478	Pan troglodytes	81.11	0.00e+00	974.00
IUUC-Pan-092653	Papio anubis	81.57	0.00e+00	982.00
IUUC-Psi-094014	Pelodiscus sinensis	84.52	0.00e+00	1010.00
IUUC-Pno-095143	Phaeosphaeria nodorum	25.32	2.00e-16	79.70
IUUC-Pfo-097316	Poecilia formosa	94.66	0.00e+00	1121.00
IUUC-Pab-098609	Pongo abelii	81.46	0.00e+00	983.00
IUUC-Pva-102527	Pteropus vampyrus	83.33	6.00e-142	497.00
IUUC-Rno-105188	Rattus norvegicus	81.22	0.00e+00	976.00
IUUC-Sha-106543	Sarcophilus harrisii	82.62	0.00e+00	966.00
IUUC-Sar-113507	Sorex araneus	80.17	0.00e+00	962.00
IUUC-Ssc-115803	Sus scrofa	81.74	0.00e+00	982.00
IUUC-Tgu-116661	Taeniopygia guttata	76.85	0.00e+00	839.00
IUUC-Tsy-119570	Tarsius syrichta	75.35	0.00e+00	880.00
IUUC-Tni-120041	Tetraodon nigroviridis	96.56	0.00e+00	1141.00
IUUC-Tbe-127655	Tupaia belangeri	75.22	0.00e+00	865.00
IUUC-Ttr-129249	Tursiops truncatus	81.63	0.00e+00	983.00
IUUC-Vpa-130034	Vicugna pacos	81.11	0.00e+00	980.00
IUUC-Xtr-132964	Xenopus tropicalis	82.09	0.00e+00	981.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence