iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Oar-089781

Ensembl Protein ID

ENSOARP00000007514.1

UniProt Accession

W5PAQ3; W5PAQ3_SHEEP

Genbank Protein ID

ENSOARP00000007514

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AMGL01017237

Gene Name

TRIM25

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSOARG00000007011.1	ENSOART00000007626.1	ENSOARP00000007514.1

Status

Unreviewed

Classification

Family	Identity	E-Value	Score	Source Orthology
E3 activity/RING/RING	74.89	0.00e+00	642.00	IUUC-Hsa-045828

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Organism

Ovis aries

Protein Sequence
(Fasta)

SFSLQNKLRQ KLTVMYGQIN GASRALEDVR ARQQEVQEAA HRKMDQLRQE YLEMKALIDA 60
SEASATRKIK EEEKRVTSKF DSIYQIILKK RSEIQTLKEE VELALTKGDE FEFLEKATKL 120

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Nucleotide Sequence
(Fasta)

TCGTTTTCTC TGCAGAATAA GTTGAGGCAA AAACTGACTG TCATGTACGG CCAGATCAAT 60
GGGGCATCAA GAGCGCTGGA GGACGTGAGA GCCAGGCAGC AGGAGGTGCA GGTGAGTGAT 120

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Sequence Source

Ensembl

Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR001870--B30.2/SPRY
IPR003879--Butyrophylin
IPR013320--ConA-like_dom
IPR006574--PRY
IPR003877--SPRY_dom

PROSITE

PS50188--B302_SPRY

Pfam

PF13765--PRY
PF00622--SPRY

PRINTS

PR01407--BUTYPHLNCDUF

SMART

SM00589--PRY
SM00449--SPRY

Gene Ontology

GO:0005829--C:cytosol
GO:0016604--C:nuclear body
GO:0003723--F:RNA binding
GO:1904264--F:ubiquitin protein ligase activity involved in ERAD pathway
GO:0045087--P:innate immune response
GO:0046597--P:negative regulation of viral entry into host cell
GO:1902187--P:negative regulation of viral release from host cell
GO:0043123--P:positive regulation of I-kappaB kinase/NF-kappaB signaling
GO:0051092--P:positive regulation of NF-kappaB transcription factor activity
GO:0006513--P:protein monoubiquitination
GO:0042787--P:protein ubiquitination involved in ubiquitin-dependent protein catabolic process
GO:0043627--P:response to estrogen

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002424	Ailuropoda melanoleuca	73.41	0.00e+00	645.00
IUUC-Apl-004101	Anas platyrhynchos	47.91	1.00e-116	413.00
IUUC-Aca-005025	Anolis carolinensis	45.33	4.00e-112	398.00
IUUC-Bta-012735	Bos taurus	92.73	0.00e+00	796.00
IUUC-Cja-019996	Callithrix jacchus	58.15	6.00e-72	264.00
IUUC-Cfa-020466	Canis familiaris	70.59	3.00e-178	618.00
IUUC-Cpo-021737	Cavia porcellus	64.64	5.00e-162	564.00
IUUC-Csa-023217	Chlorocebus sabaeus	73.98	0.00e+00	637.00
IUUC-Dno-030082	Dasypus novemcinctus	69.34	2.00e-174	605.00
IUUC-Dor-030335	Dipodomys ordii	58.41	5.00e-94	338.00
IUUC-Ete-032923	Echinops telfairi	66.67	8.00e-148	517.00
IUUC-Eca-033411	Equus caballus	69.76	0.00e+00	637.00
IUUC-Eeu-034656	Erinaceus europaeus	83.82	6.00e-92	331.00
IUUC-Fca-035371	Felis catus	70.85	0.00e+00	628.00
IUUC-Fal-037008	Ficedula albicollis	44.16	2.00e-105	376.00
IUUC-Gga-040608	Gallus gallus	46.15	9.00e-116	410.00
IUUC-Gac-041409	Gasterosteus aculeatus	50.55	1.00e-55	211.00
IUUC-Ggo-044518	Gorilla gorilla	71.52	2.00e-176	612.00
IUUC-Hsa-045828	Homo sapiens	74.21	0.00e+00	634.00
IUUC-Itr-049070	Ictidomys tridecemlineatus	82.51	2.00e-96	345.00
IUUC-Lch-050478	Latimeria chalumnae	47.39	2.00e-56	213.00
IUUC-Loc-052864	Lepisosteus oculatus	32.33	2.00e-63	236.00
IUUC-Laf-054325	Loxodonta africana	72.16	1.00e-71	263.00
IUUC-Mcc-054920	Macaca mulatta	74.66	0.00e+00	644.00
IUUC-Meu-056367	Macropus eugenii	73.41	1.00e-74	274.00
IUUC-Mga-059975	Meleagris gallopavo	47.09	2.00e-114	406.00
IUUC-Mmr-060748	Microcebus murinus	73.29	1.00e-180	626.00
IUUC-Mdo-062904	Monodelphis domestica	57.99	3.00e-128	452.00
IUUC-Mmu-063891	Mus musculus	64.86	1.00e-165	576.00
IUUC-Mpu-066473	Mustela putorius furo	70.77	0.00e+00	642.00
IUUC-Mlu-068185	Myotis lucifugus	71.08	0.00e+00	638.00
IUUC-Nle-070177	Nomascus leucogenys	71.72	0.00e+00	642.00
IUUC-Opr-070558	Ochotona princeps	50.00	1.00e-59	223.00
IUUC-Ont-071368	Oreochromis niloticus	30.66	6.00e-59	221.00
IUUC-Ocu-074461	Oryctolagus cuniculus	50.89	2.00e-103	370.00
IUUC-Oga-088937	Otolemur garnettii	65.92	3.00e-157	548.00
IUUC-Ptr-090771	Pan troglodytes	73.98	3.00e-176	611.00
IUUC-Pan-092830	Papio anubis	74.66	0.00e+00	645.00
IUUC-Psi-093664	Pelodiscus sinensis	66.84	2.00e-82	300.00
IUUC-Pfo-096528	Poecilia formosa	30.54	1.00e-62	234.00
IUUC-Pab-097588	Pongo abelii	74.21	1.00e-179	622.00
IUUC-Pca-100890	Procavia capensis	83.51	2.00e-99	356.00
IUUC-Pva-102314	Pteropus vampyrus	75.62	0.00e+00	628.00
IUUC-Rno-105234	Rattus norvegicus	74.57	3.00e-103	369.00
IUUC-Sha-106807	Sarcophilus harrisii	53.49	1.00e-123	437.00
IUUC-Tgu-117026	Taeniopygia guttata	46.42	2.00e-102	366.00
IUUC-Tru-117794	Takifugu rubripes	47.70	3.00e-47	182.00
IUUC-Tbe-127580	Tupaia belangeri	69.31	9.00e-71	260.00
IUUC-Ttr-128648	Tursiops truncatus	76.14	0.00e+00	656.00
IUUC-Vpa-130254	Vicugna pacos	88.57	3.00e-97	348.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence