iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Dre-027449

UUCD1 version

UUC-DaR-01348

Ensembl Protein ID

ENSDARP00000049374.6

UniProt Accession

Q6DG68; Q6DG68_DANRE

Genbank Protein ID

AAH76483.1; AAI50449.1; AAI65379.1

Protein Name

Ubiquitin-conjugating enzyme E2E 2; Zgc:92467; Zgc:92467 protein

Genbank Nucleotide ID

CABZ01056120; BC150448; BC165379

Gene Name

ube2e2; zgc:92467

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSDARG00000034670.8	ENSDART00000049375.7	ENSDARP00000049374.6

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E2/UBC	1.50e-49	168.2	59	193

Active Site

Position(s)	Description	Evidence
139	Glycyl thioester intermediate	{ECO:0000256\|PROSITE-ProRule:PRU00388}

Domain Profile

E2/UBC

   S: 1    RlkkelkelekdppegisakpvdesdltewevlilGpedtpYeggvFkleiefpedYPfkPPkvkfltkifhPnvyenGkvClsilkee 89
           R++kel+e++ dpp+++sa+p+ + +++ew+ +ilGp++++YeggvF l+i f++dYPfkPPkv+f t+i+h+n++++G +Cl+ilk  
   Q: 59   RIQKELAEITLDPPPNCSAGPKGD-NIYEWRSTILGPPGSVYEGGVFFLDIAFTPDYPFKPPKVTFRTRIYHCNINSQGVICLDILK-- 144
           9***********************.9************************************************************9.. PP
   S: 90   ekWspalsvesvllsiqsllaepnpesplneeaaellkknreeykkkvr 138
           ++Wspal++++vllsi+sll+++np++pl  ++a+++ +nr+e++++++
   Q: 145  DNWSPALTISKVLLSICSLLTDCNPADPLVGSIATQYLTNRTEHDRIAK 193
           ********************************************99987 PP

Organism

Danio rerio

Protein Sequence
(Fasta)

MSSEVQRPDD SPSTSGGSSD IEQRETAPPQ QERDLVAPKK KETKISSKTA AKLSTSAKRI 60
QKELAEITLD PPPNCSAGPK GDNIYEWRST ILGPPGSVYE GGVFFLDIAF TPDYPFKPPK 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CGCGTAGAGG CGGTCCGGCT GCTTCAGTTT CTGTAATCGC TTTTTTTCTG CTACCTTCAG 60
TTAAATAGCG ACGAGACGAG AGAGAGCGGA CGGCCCGACT CTGACTACAC TGTATCATTC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0067--ATP-binding
KW-0181--Complete proteome
KW-0547--Nucleotide-binding
KW-1185--Reference proteome
KW-0833--Ubl conjugation pathway

Interpro

IPR000608--UBQ-conjugat_E2
IPR023313--UBQ-conjugating_AS
IPR016135--UBQ-conjugating_enzyme/RWD

PROSITE

PS00183--UBIQUITIN_CONJUGAT_1
PS50127--UBIQUITIN_CONJUGAT_2

Pfam

PF00179--UQ_con

Gene Ontology

GO:0005524--F:ATP binding

KEGG

dre:445100

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001532	Ailuropoda melanoleuca	92.90	6.00e-86	309.00
IUUC-Apl-004207	Anas platyrhynchos	92.90	2.00e-85	308.00
IUUC-Aca-005044	Anolis carolinensis	90.05	6.00e-89	319.00
IUUC-Ame-011419	Astyanax mexicanus	100.00	3.00e-84	304.00
IUUC-Cja-019311	Callithrix jacchus	92.90	7.00e-86	309.00
IUUC-Cfa-020524	Canis familiaris	92.41	6.00e-85	306.00
IUUC-Cpo-022266	Cavia porcellus	92.90	7.00e-86	309.00
IUUC-Csa-023538	Chlorocebus sabaeus	92.90	7.00e-86	309.00
IUUC-Cho-024986	Choloepus hoffmanni	79.60	2.00e-76	278.00
IUUC-Csv-025982	Ciona savignyi	83.87	8.00e-80	289.00
IUUC-Dor-030450	Dipodomys ordii	97.27	5.00e-62	228.00
IUUC-Dme-032042	Drosophila melanogaster	87.65	8.00e-84	303.00
IUUC-Ete-032397	Echinops telfairi	88.30	4.00e-89	320.00
IUUC-Eeu-034931	Erinaceus europaeus	86.07	1.00e-82	298.00
IUUC-Gmo-039645	Gadus morhua	94.09	5.00e-92	330.00
IUUC-Gac-041661	Gasterosteus aculeatus	96.52	2.00e-95	341.00
IUUC-Ggo-045507	Gorilla gorilla	92.90	7.00e-86	309.00
IUUC-Lch-050322	Latimeria chalumnae	87.86	7.00e-89	319.00
IUUC-Loc-052673	Lepisosteus oculatus	93.53	2.00e-91	328.00
IUUC-Laf-054313	Loxodonta africana	92.90	7.00e-86	309.00
IUUC-Mmu-063733	Mus musculus	89.05	2.00e-88	317.00
IUUC-Mpu-065698	Mustela putorius furo	88.44	3.00e-90	323.00
IUUC-Ont-071325	Oreochromis niloticus	96.02	1.00e-94	338.00
IUUC-Ocu-074055	Oryctolagus cuniculus	92.90	7.00e-86	309.00
IUUC-Ola-086636	Oryzias latipes	97.20	2.00e-82	298.00
IUUC-Oga-088863	Otolemur garnettii	92.90	7.00e-86	309.00
IUUC-Oar-089803	Ovis aries	88.44	3.00e-90	323.00
IUUC-Ptr-090914	Pan troglodytes	92.90	7.00e-86	309.00
IUUC-Pan-092786	Papio anubis	92.90	7.00e-86	309.00
IUUC-Psi-093923	Pelodiscus sinensis	92.90	7.00e-86	309.00
IUUC-Pfo-097071	Poecilia formosa	91.75	3.00e-91	327.00
IUUC-Rno-105518	Rattus norvegicus	88.89	2.00e-89	321.00
IUUC-Sit-109845	Setaria italica	65.03	5.00e-53	200.00
IUUC-Tgu-116958	Taeniopygia guttata	95.30	1.00e-84	305.00
IUUC-Tru-118527	Takifugu rubripes	80.98	7.00e-85	306.00
IUUC-Tni-119832	Tetraodon nigroviridis	76.47	2.00e-86	311.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence