iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSMUSG00000040389.15	ENSMUST00000051145.14	ENSMUSP00000057482.8
ENSMUSG00000040389.15	ENSMUST00000124731.2	ENSMUSP00000143335.1

Annotation

Single Nucleotide Polymorphisms (SNP)
dbSNP
mRNA Expression
GEO	ArrayExpress	GXD
DNA & RNA Element
AREsite	miRTarBase	microRNA	TRANSFAC
RepTar	miRNAMap	RAID2
Protein-protein Interaction
IID	Mentha
Post-translational Modifications (PTMs)
CPLM	dbPAF	PhosphositePlus	dbPTM
UniProt	PHOSIDA	mUbiSiDa
Protein Expression/Proteomics
GPMDB

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	3.00e-29	100.9	754	790
UBD/Beta-Prp	4.90e-59	201.1	658	916

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 1    gHtdsvtcla.fsdtllvsGsdDgtikvWDlrtgvll 36
           gHt+ + +l  +s+++++sGs D+t++ WDlr   ++
   Q: 754  GHTGHILALYtWSGWMIASGSQDKTVRFWDLRVPSCV 790
           89999***966977*****************988887 PP

UBD/Beta-Prp

   S: 6    kghhksvitcvkfspdksllatgsrdgtikvwdvttgkl.....lrslsgheaevtavkfspdgk....ilvtgse.Drtikvwdlstg 84
           ++hhk+ i+cv++sp ++llatgs d+ +kv  +  +++       ++s h+++++++ f +  +    il++++  D +i+  d + g
   Q: 658  NKHHKGSIYCVAWSPCGQLLATGSNDKYVKVLPFNAETCnatgpDLEFSMHDGTIRDLAFMEGPEsggaILISAGAgDCNIYTTDCQRG 746
           68*****************************99999999889888899************987667778777765516788888***** PP
   S: 85   kcvhtlkghedsvlslsfspsgdklvsGshdrtirvwdletgqclee...tlsghdgvvncvvvhpdgnllvsGslDrtvrlWdlktgk 170
           + +h+l+gh+  +l+l     g  ++sGs+d+t+r wdl+  +c++    t+ g+ ++v +v+v+p+g+ll++G  D+ ++l+d++ g+
   Q: 747  QGLHALSGHTGHILALYTWS-GWMIASGSQDKTVRFWDLRVPSCVRVvgtTFHGTGSAVASVAVDPSGRLLATGQEDSSCMLYDIRGGR 834
           **************997777.9***********************99999*************************************** PP
   S: 171  llrtltgghtdsvyslsfdsngkelvsgsldgtvklwdlq....tgecvrtlnghtdnvksvrfspnderlvsgssDgsiriW 249
           +++     h ++v+s+ f++   +l++gs+d ++k+ dlq    ++  ++ + +h+d v + r + +d  ++s s+D+++ +W
   Q: 835  MVQSYHP-HSSDVRSVRFSPGAHYLLTGSYDMKIKVTDLQgdltKQLPLMVVGEHKDKVIQCRWHTQDLSFLSSSADRTVTLW 916
           *****98.********************************99977778*********************************** PP

Organism

Mus musculus

Protein Sequence
(Fasta)

MTAEETVNVK EVEIIKLILD FLNSKKLHIS MLALEKESGV INGLFSDDML FLRQLILDGQ 60
WDEVLQFIQP LECMEKFDKK RFRYIILKQK FLEALCVNNA MSAEDEPQHL EFTMQEAVQC 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GCCTAGCCGC CTCGCGAGGA GGGGTCCTGA GGCGGCTCCA GGGACGAGCA GTGATTGGCT 60
GCAGCTGGCG GCTGGAGCTC CGTTCCAGCG GCGCTTGACA ACCGCAGTCC GCGGAGCGGA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0963--Cytoplasm
KW-0206--Cytoskeleton
KW-0217--Developmental protein
KW-0493--Microtubule
KW-0597--Phosphoprotein
KW-1185--Reference proteome
KW-0677--Repeat
KW-0853--WD repeat

Interpro

IPR024977--Apc4_WD40_dom
IPR006595--CTLH_C
IPR006594--LisH
IPR027295--Quinoprotein_ADH-like_fam
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS50897--CTLH
PS50896--LISH
PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF12894--ANAPC4_WD40
PF00400--WD40

SMART

SM00668--CTLH
SM00667--LisH
SM00320--WD40

Gene Ontology

GO:0005737--C:cytoplasm
GO:0005874--C:microtubule
GO:0007275--P:multicellular organism development

KEGG

mmu:99512

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001519	Ailuropoda melanoleuca	95.58	0.00e+00	1630.00
IUUC-Apl-003954	Anas platyrhynchos	90.57	0.00e+00	1541.00
IUUC-Aca-004766	Anolis carolinensis	88.29	0.00e+00	1484.00
IUUC-Ame-010725	Astyanax mexicanus	69.38	0.00e+00	1116.00
IUUC-Bta-013072	Bos taurus	94.35	0.00e+00	1593.00
IUUC-Cel-018667	Caenorhabditis elegans	48.02	9.00e-94	338.00
IUUC-Cja-018835	Callithrix jacchus	94.61	0.00e+00	1604.00
IUUC-Cfa-020380	Canis familiaris	92.61	0.00e+00	979.00
IUUC-Cpo-021883	Cavia porcellus	94.78	0.00e+00	1576.00
IUUC-Csa-023467	Chlorocebus sabaeus	95.33	0.00e+00	1618.00
IUUC-Cho-024342	Choloepus hoffmanni	85.64	0.00e+00	1441.00
IUUC-Cin-025112	Ciona intestinalis	43.89	9.00e-74	270.00
IUUC-Dre-027530	Danio rerio	76.55	0.00e+00	1257.00
IUUC-Dno-029290	Dasypus novemcinctus	95.55	0.00e+00	1613.00
IUUC-Dor-030258	Dipodomys ordii	82.19	0.00e+00	1355.00
IUUC-Dme-032040	Drosophila melanogaster	53.03	2.00e-103	369.00
IUUC-Ete-032248	Echinops telfairi	88.64	0.00e+00	778.00
IUUC-Eca-033623	Equus caballus	95.77	0.00e+00	1618.00
IUUC-Fca-036425	Felis catus	94.09	0.00e+00	1429.00
IUUC-Fal-036661	Ficedula albicollis	89.91	0.00e+00	1518.00
IUUC-Gmo-039527	Gadus morhua	73.45	0.00e+00	1223.00
IUUC-Gga-041177	Gallus gallus	89.69	0.00e+00	1509.00
IUUC-Gac-042049	Gasterosteus aculeatus	74.05	0.00e+00	1238.00
IUUC-Ggo-044833	Gorilla gorilla	94.71	0.00e+00	1616.00
IUUC-Hsa-046084	Homo sapiens	94.82	0.00e+00	1617.00
IUUC-Lch-050313	Latimeria chalumnae	79.81	0.00e+00	1388.00
IUUC-Loc-051790	Lepisosteus oculatus	80.36	0.00e+00	1393.00
IUUC-Laf-053521	Loxodonta africana	94.57	0.00e+00	1597.00
IUUC-Mcc-055053	Macaca mulatta	95.33	0.00e+00	1618.00
IUUC-Meu-056734	Macropus eugenii	93.80	0.00e+00	694.00
IUUC-Mga-059381	Meleagris gallopavo	89.91	0.00e+00	1519.00
IUUC-Mmr-060859	Microcebus murinus	95.15	0.00e+00	1616.00
IUUC-Mdo-062501	Monodelphis domestica	91.76	0.00e+00	1453.00
IUUC-Mpu-066718	Mustela putorius furo	95.64	0.00e+00	1279.00
IUUC-Mlu-067246	Myotis lucifugus	95.22	0.00e+00	1609.00
IUUC-Nle-069807	Nomascus leucogenys	94.82	0.00e+00	1618.00
IUUC-Opr-070862	Ochotona princeps	65.64	2.00e-88	320.00
IUUC-Ont-072519	Oreochromis niloticus	76.00	0.00e+00	1251.00
IUUC-Oan-072740	Ornithorhynchus anatinus	87.81	0.00e+00	776.00
IUUC-Ocu-074898	Oryctolagus cuniculus	95.76	0.00e+00	1592.00
IUUC-Ola-086396	Oryzias latipes	76.12	0.00e+00	1288.00
IUUC-Oga-088563	Otolemur garnettii	94.71	0.00e+00	1608.00
IUUC-Oar-089926	Ovis aries	95.33	0.00e+00	1612.00
IUUC-Ptr-090706	Pan troglodytes	94.71	0.00e+00	1615.00
IUUC-Pan-091740	Papio anubis	95.43	0.00e+00	1619.00
IUUC-Psi-093938	Pelodiscus sinensis	89.86	0.00e+00	1533.00
IUUC-Pfo-096531	Poecilia formosa	76.67	0.00e+00	1256.00
IUUC-Pab-098312	Pongo abelii	95.22	0.00e+00	1617.00
IUUC-Pca-101100	Procavia capensis	88.24	0.00e+00	721.00
IUUC-Pva-102734	Pteropus vampyrus	91.00	0.00e+00	723.00
IUUC-Rno-105625	Rattus norvegicus	98.05	0.00e+00	1612.00
IUUC-Sha-106999	Sarcophilus harrisii	90.14	0.00e+00	1499.00
IUUC-Sar-112988	Sorex araneus	83.52	0.00e+00	1171.00
IUUC-Ssc-115384	Sus scrofa	95.01	0.00e+00	1582.00
IUUC-Tgu-116808	Taeniopygia guttata	90.03	0.00e+00	1515.00
IUUC-Tru-118233	Takifugu rubripes	76.15	0.00e+00	1228.00
IUUC-Tsy-119509	Tarsius syrichta	98.94	0.00e+00	679.00
IUUC-Tni-120473	Tetraodon nigroviridis	74.19	0.00e+00	1248.00
IUUC-Tbe-127447	Tupaia belangeri	90.74	4.00e-146	511.00
IUUC-Ttr-128459	Tursiops truncatus	92.94	0.00e+00	1486.00
IUUC-Vpa-130258	Vicugna pacos	90.03	0.00e+00	993.00
IUUC-Xtr-132609	Xenopus tropicalis	79.57	0.00e+00	1320.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence