iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Mpu-066131

Ensembl Protein ID

ENSMPUP00000003287.1

UniProt Accession

M3XW37; M3XW37_MUSPF

Genbank Protein ID

ENSMPUP00000003287

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AEYP01077146

Gene Name

TLE6

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSMPUG00000003319.1	ENSMPUT00000003352.1	ENSMPUP00000003287.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	9.20e-11	41.6	309	342

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 7    tclaf...sd.tllvsGsdDgtikvWDlrtgvll 36
           tc a+   ++ tl  +G  Dgt++vWDlr++  +
   Q: 309  TCQALasgPEaTLAFAGFTDGTVRVWDLRDQSIV 342
           676777777788888999***********98766 PP

Organism

Mustela putorius furo

Protein Sequence
(Fasta)

MESFLRTVET WSQALGFQPA EASPEASLHP EAETPQPSGL QGPPFEDVLA ARSSDWLRQP 60
SRAGTGPPMP DTQSPWDPEP RFWQDVLTEQ LWQIFMGTHK RDQRRRTTER LPGLGQESQD 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CCGCATCACA GAATGACTTC CCTGGAGCCC ACTACTAGCT GGGGCAGCCA GAGGCACCAG 60
AGTTTGACAA AGGAACAGAG GGTATATAGG GCACCCAGTG GGGTGCTAGA AGTCAGGGAG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0853--WD repeat

Interpro

IPR009146--Groucho_enhance
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF00400--WD40

PRINTS

PR01850--GROUCHOFAMLY

SMART

SM00320--WD40

Gene Ontology

GO:0005938--C:cell cortex
GO:0005634--C:nucleus
GO:0043234--C:protein complex
GO:0045666--P:positive regulation of neuron differentiation
GO:0006355--P:regulation of transcription, DNA-templated

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002169	Ailuropoda melanoleuca	81.72	0.00e+00	660.00
IUUC-Bta-012704	Bos taurus	68.20	9.00e-171	593.00
IUUC-Cfa-020822	Canis familiaris	84.64	2.00e-137	481.00
IUUC-Cpo-021589	Cavia porcellus	53.80	8.00e-101	360.00
IUUC-Csa-023760	Chlorocebus sabaeus	61.28	2.00e-163	569.00
IUUC-Dno-029434	Dasypus novemcinctus	53.91	1.00e-71	264.00
IUUC-Dor-030782	Dipodomys ordii	59.02	4.00e-112	397.00
IUUC-Eca-033556	Equus caballus	81.79	2.00e-159	554.00
IUUC-Fca-035421	Felis catus	75.05	0.00e+00	635.00
IUUC-Ggo-044650	Gorilla gorilla	61.03	2.00e-155	542.00
IUUC-Hsa-046311	Homo sapiens	61.68	4.00e-162	564.00
IUUC-Itr-048864	Ictidomys tridecemlineatus	62.74	1.00e-73	268.00
IUUC-Laf-053971	Loxodonta africana	61.64	7.00e-106	376.00
IUUC-Mcc-055698	Macaca mulatta	61.46	2.00e-164	572.00
IUUC-Mmr-061647	Microcebus murinus	62.71	2.00e-163	568.00
IUUC-Mmu-064062	Mus musculus	45.34	6.00e-116	411.00
IUUC-Mlu-068020	Myotis lucifugus	69.05	8.00e-175	606.00
IUUC-Oga-088838	Otolemur garnettii	68.78	1.00e-95	342.00
IUUC-Oar-090417	Ovis aries	68.64	2.00e-171	595.00
IUUC-Ptr-090523	Pan troglodytes	61.08	6.00e-152	530.00
IUUC-Pan-092275	Papio anubis	61.07	1.00e-161	563.00
IUUC-Pab-097952	Pongo abelii	69.62	2.00e-116	411.00
IUUC-Pva-102968	Pteropus vampyrus	69.76	4.00e-173	600.00
IUUC-Rno-105186	Rattus norvegicus	46.44	5.00e-112	398.00
IUUC-Ssc-116390	Sus scrofa	66.96	1.00e-167	582.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence