iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Uma-129435

Ensembl Protein ID

KIS66579

UniProt Accession

Q4P2U6; A0A0D1DQB5; ATG8_USTMA

Genbank Protein ID

KIS66579.1

Protein Name

Autophagy-related protein 8; Autophagy-related ubiquitin-like modifier atg8

Genbank Nucleotide ID

CM003157

Gene Name

ATG8; UMAG_05567

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
UMAG_05567	KIS66579	KIS66579

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
ULD/UBL/ATG8	1.20e-48	162.0	13	116

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

ULD/UBL/ATG8

   S: 1    krkeevekirdkfpdkiPvivekakkekipeldkkkylvPsdltvgqlvkiirkrlqlraedalfllvnnslvsvsatlaeiyeeekdedgflyvayasee 101
           krk+e+e+ir+k+pd+iPvi+eka++++ip++dkkkylvPsdltvgq+v++irkr++l +e+a+f++v+++l++++a +++iyee+kdedgflyv+y++e+
   Q: 13   KRKAEAERIRQKYPDRIPVICEKADRTDIPTIDKKKYLVPSDLTVGQFVYVIRKRIKLAPEKAIFIFVDEVLPATAALMSAIYEEHKDEDGFLYVSYSGEN 113
           699************************************************************************************************** PP
   S: 102  tfG 104
           tfG
   Q: 114  TFG 116
           **9 PP

Organism

Ustilago maydis

Functional Description
(View)

Ubiquitin-like modifier involved in autophagosomes formation. With ATG4, mediates the delivery of the autophagosomes to the vacuole via the microtubule cytoskeleton. Participates also in membrane fusion events that take place in the early secretory pathway. Also involved in endoplasmic reticulum-specific autophagic process and is essential for the survival of cells subjected to severe ER stress. The ATG8-PE conjugate mediates tethering between adjacent membranes and stimulates membrane hemifusion, leading to expansion of the autophagosomal membrane during autophagy (By similarity). Required for selective autophagic degradation of the mitochondria (mitophagy) which contributes to regulate mitochondrial quantity and quality by eliminating the mitochondria to a basal level to fulfill cellular energy requirements and preventing excess ROS production. Required for wild-type budding of haploid sporidia and for complete symptom development during pathogenic growth such as gall formation and teliospore production in ears of mature maize (PubMed:20618705, PubMed:22843561).

Protein Sequence
(Fasta)

MRSAFKNEHS FEKRKAEAER IRQKYPDRIP VICEKADRTD IPTIDKKKYL VPSDLTVGQF 60
VYVIRKRIKL APEKAIFIFV DEVLPATAAL MSAIYEEHKD EDGFLYVSYS GENTFGQL 118

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGCGTTCCG CATTCAAGAA CGAGCACTCT TTTGAGAAGC GCAAGGCTGA GGCCGAGAGG 60
ATCCGTCAGA AGTACCCGGA CCGCATCCCT GTCATCTGCG AAAAGGCTGA CCGCACCGAC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0072--Autophagy
KW-0181--Complete proteome
KW-0968--Cytoplasmic vesicle
KW-0449--Lipoprotein
KW-0472--Membrane
KW-0653--Protein transport
KW-1185--Reference proteome
KW-0813--Transport
KW-0833--Ubl conjugation pathway
KW-0926--Vacuole
KW-0843--Virulence

Interpro

IPR004241--Atg8-like
IPR029071--Ubiquitin-rel_dom

Pfam

PF02991--Atg8

Gene Ontology

GO:0000421--C:autophagosome membrane
GO:0031410--C:cytoplasmic vesicle
GO:0006914--P:autophagy
GO:0009405--P:pathogenesis
GO:0015031--P:protein transport

KEGG

uma:UMAG_05567

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000059	Aegilops tauschii	74.14	9.00e-51	189.00
IUUC-Aml-001629	Ailuropoda melanoleuca	60.34	4.00e-40	154.00
IUUC-Atr-002791	Amborella trichopoda	80.34	5.00e-53	197.00
IUUC-Apl-003994	Anas platyrhynchos	56.90	1.00e-37	146.00
IUUC-Aca-005288	Anolis carolinensis	59.48	8.00e-40	153.00
IUUC-Aly-005554	Arabidopsis lyrata	80.00	2.00e-45	172.00
IUUC-Ath-006958	Arabidopsis thaliana	79.13	6.00e-45	170.00
IUUC-Ago-007898	Ashbya gossypii	71.05	1.00e-47	179.00
IUUC-Acl-008314	Aspergillus clavatus	87.07	2.00e-57	211.00
IUUC-Afl-008708	Aspergillus flavus	86.44	6.00e-58	213.00
IUUC-Afu-009097	Aspergillus fumigatus	87.07	2.00e-57	211.00
IUUC-Ani-009196	Aspergillus nidulans	86.21	1.00e-56	209.00
IUUC-Ang-009530	Aspergillus niger	87.07	2.00e-57	211.00
IUUC-Aor-009909	Aspergillus oryzae	86.44	6.00e-58	213.00
IUUC-Ate-010358	Aspergillus terreus	87.07	2.00e-57	211.00
IUUC-Ame-010751	Astyanax mexicanus	60.34	2.00e-40	155.00
IUUC-Bgr-012248	Blumeria graminis	86.32	4.00e-57	211.00
IUUC-Bta-012520	Bos taurus	60.34	5.00e-40	154.00
IUUC-Bci-013959	Botrytis cinerea	88.03	2.00e-58	215.00
IUUC-Bdi-014320	Brachypodium distachyon	80.00	8.00e-52	193.00
IUUC-Bol-015168	Brassica oleracea	80.87	7.00e-52	195.00
IUUC-Bra-017452	Brassica rapa	80.87	1.00e-52	196.00
IUUC-Cel-018200	Caenorhabditis elegans	57.76	6.00e-39	150.00
IUUC-Cja-019273	Callithrix jacchus	59.48	8.00e-40	153.00
IUUC-Cfa-020373	Canis familiaris	60.34	4.00e-40	154.00
IUUC-Cpo-021831	Cavia porcellus	60.34	4.00e-40	154.00
IUUC-Cre-022866	Chlamydomonas reinhardtii	83.19	4.00e-47	178.00
IUUC-Csa-024201	Chlorocebus sabaeus	60.34	4.00e-40	154.00
IUUC-Cho-025008	Choloepus hoffmanni	52.99	3.00e-35	138.00
IUUC-Cin-025297	Ciona intestinalis	57.76	5.00e-39	150.00
IUUC-Csv-026146	Ciona savignyi	38.46	4.00e-23	98.20
IUUC-Cgl-026691	Colletotrichum gloeosporioides	63.12	8.00e-51	191.00
IUUC-Cne-026889	Cryptococcus neoformans	83.90	2.00e-56	208.00
IUUC-Dre-028371	Danio rerio	59.48	1.00e-39	152.00
IUUC-Dno-029331	Dasypus novemcinctus	60.34	3.00e-40	154.00
IUUC-Dor-030453	Dipodomys ordii	60.34	4.00e-40	154.00
IUUC-Dse-031428	Dothistroma septosporum	86.32	8.00e-58	213.00
IUUC-Dme-031813	Drosophila melanogaster	60.34	2.00e-40	155.00
IUUC-Ete-032671	Echinops telfairi	59.48	8.00e-39	150.00
IUUC-Eca-034113	Equus caballus	60.34	6.00e-40	154.00
IUUC-Eeu-035131	Erinaceus europaeus	55.81	2.00e-25	104.00
IUUC-Fca-036385	Felis catus	60.34	4.00e-40	154.00
IUUC-Fal-036896	Ficedula albicollis	59.48	1.00e-39	152.00
IUUC-Fox-037846	Fusarium oxysporum	87.07	1.00e-57	212.00
IUUC-Fso-038134	Fusarium solani	87.07	2.00e-57	212.00
IUUC-Gmo-039289	Gadus morhua	59.48	7.00e-40	153.00
IUUC-Ggr-039770	Gaeumannomyces graminis	82.20	3.00e-55	204.00
IUUC-Gga-040257	Gallus gallus	58.62	1.00e-38	149.00
IUUC-Gac-041604	Gasterosteus aculeatus	60.34	4.00e-40	154.00
IUUC-Gma-043572	Glycine max	80.34	7.00e-46	173.00
IUUC-Ggo-044429	Gorilla gorilla	60.34	4.00e-40	154.00
IUUC-Hsa-046764	Homo sapiens	60.34	4.00e-40	154.00
IUUC-Hvu-047588	Hordeum vulgare	76.92	1.00e-50	189.00
IUUC-Itr-048405	Ictidomys tridecemlineatus	58.62	2.00e-38	149.00
IUUC-Kpa-049124	Komagataella pastoris	77.12	7.00e-52	193.00
IUUC-Lch-049542	Latimeria chalumnae	59.48	4.00e-40	154.00
IUUC-Lpe-051292	Leersia perrieri	80.00	2.00e-52	195.00
IUUC-Loc-052290	Lepisosteus oculatus	58.62	3.00e-38	149.00
IUUC-Laf-054203	Loxodonta africana	58.62	2.00e-38	149.00
IUUC-Mcc-055307	Macaca mulatta	58.62	2.00e-38	149.00
IUUC-Meu-056515	Macropus eugenii	60.34	4.00e-40	154.00
IUUC-Mor-057276	Magnaporthe oryzae	83.05	1.00e-55	206.00
IUUC-Mpo-057469	Magnaporthe poae	81.36	2.00e-54	202.00
IUUC-Mtr-058417	Medicago truncatula	80.34	9.00e-46	173.00
IUUC-Mla-059098	Melampsora laricipopulina	95.69	1.00e-62	229.00
IUUC-Mga-060108	Meleagris gallopavo	55.93	8.00e-38	147.00
IUUC-Mvi-060496	Microbotryum violaceum	90.43	3.00e-59	218.00
IUUC-Mmr-061776	Microcebus murinus	58.62	2.00e-38	149.00
IUUC-Mdo-061915	Monodelphis domestica	60.34	5.00e-40	154.00
IUUC-Mmu-064152	Mus musculus	60.34	4.00e-40	154.00
IUUC-Mac-064522	Musa acuminata	77.78	2.00e-45	171.00
IUUC-Mpu-066760	Mustela putorius furo	60.34	4.00e-40	154.00
IUUC-Mlu-068211	Myotis lucifugus	60.34	4.00e-40	154.00
IUUC-Nfi-068367	Neosartorya fischeri	87.07	2.00e-57	211.00
IUUC-Ncr-068894	Neurospora crassa	85.59	1.00e-57	212.00
IUUC-Nle-069755	Nomascus leucogenys	60.34	4.00e-40	154.00
IUUC-Opr-070777	Ochotona princeps	58.62	2.00e-38	149.00
IUUC-Ont-072343	Oreochromis niloticus	60.34	4.00e-40	154.00
IUUC-Oan-073485	Ornithorhynchus anatinus	61.90	2.00e-36	142.00
IUUC-Ocu-073861	Oryctolagus cuniculus	60.34	4.00e-40	154.00
IUUC-Oba-075722	Oryza barthii	77.78	3.00e-52	194.00
IUUC-Obr-076374	Oryza brachyantha	80.00	7.00e-52	193.00
IUUC-Ogl-077551	Oryza glaberrima	77.78	3.00e-52	194.00
IUUC-Ogu-078499	Oryza glumaepatula	77.78	3.00e-52	194.00
IUUC-Oin-079771	Oryza indica	80.00	7.00e-52	193.00
IUUC-Olo-080412	Oryza longistaminata	80.00	7.00e-52	193.00
IUUC-Ome-081791	Oryza meridionalis	80.00	7.00e-52	193.00
IUUC-Oni-082774	Oryza nivara	80.00	7.00e-52	193.00
IUUC-Opu-083486	Oryza punctata	80.00	3.00e-51	193.00
IUUC-Oru-084425	Oryza rufipogon	77.78	7.00e-52	193.00
IUUC-Osa-085439	Oryza sativa	80.00	7.00e-52	193.00
IUUC-Ola-086310	Oryzias latipes	59.48	1.00e-39	152.00
IUUC-Olu-087892	Ostreococcus lucimarinus	77.88	2.00e-50	189.00
IUUC-Oga-088483	Otolemur garnettii	60.34	4.00e-40	154.00
IUUC-Oar-089989	Ovis aries	58.62	2.00e-38	149.00
IUUC-Ptr-091560	Pan troglodytes	60.34	4.00e-40	154.00
IUUC-Pan-092269	Papio anubis	60.34	4.00e-40	154.00
IUUC-Psi-093055	Pelodiscus sinensis	56.41	8.00e-38	146.00
IUUC-Pma-094337	Petromyzon marinus	57.26	8.00e-41	157.00
IUUC-Pno-095035	Phaeosphaeria nodorum	86.32	1.00e-57	212.00
IUUC-Ppa-095257	Physcomitrella patens	78.26	4.00e-51	191.00
IUUC-Pfo-096380	Poecilia formosa	59.48	6.00e-40	154.00
IUUC-Pab-098563	Pongo abelii	60.34	4.00e-40	154.00
IUUC-Pop-100069	Populus trichocarpa	80.87	1.00e-45	173.00
IUUC-Pca-100230	Procavia capensis	58.62	2.00e-38	149.00
IUUC-Ppe-101863	Prunus persica	81.74	2.00e-45	172.00
IUUC-Pva-103103	Pteropus vampyrus	56.41	8.00e-38	146.00
IUUC-Pte-104230	Pyrenophora teres	86.32	1.00e-57	213.00
IUUC-Rno-105111	Rattus norvegicus	60.34	4.00e-40	154.00
IUUC-Sce-106150	Saccharomyces cerevisiae	76.07	3.00e-51	191.00
IUUC-Sha-106656	Sarcophilus harrisii	58.62	2.00e-38	149.00
IUUC-Sja-107857	Schizosaccharomyces japonicus	82.05	6.00e-56	207.00
IUUC-Spo-108156	Schizosaccharomyces pombe	80.51	3.00e-48	181.00
IUUC-Ssl-108578	Sclerotinia sclerotiorum	88.03	1.00e-58	215.00
IUUC-Smo-109082	Selaginella moellendorffii	80.87	4.00e-53	197.00
IUUC-Sit-110531	Setaria italica	79.82	2.00e-51	192.00
IUUC-Sly-111799	Solanum lycopersicum	78.63	1.00e-46	176.00
IUUC-Stu-112612	Solanum tuberosum	78.63	3.00e-52	194.00
IUUC-Sar-113670	Sorex araneus	53.45	4.00e-34	134.00
IUUC-Sbi-114346	Sorghum bicolor	80.00	8.00e-52	193.00
IUUC-Sre-114964	Sporisorium reilianum	100.00	2.00e-65	238.00
IUUC-Ssc-115828	Sus scrofa	60.34	4.00e-40	154.00
IUUC-Tgu-117195	Taeniopygia guttata	59.48	1.00e-39	153.00
IUUC-Tru-118632	Takifugu rubripes	58.62	2.00e-38	149.00
IUUC-Tsy-118919	Tarsius syrichta	56.41	8.00e-38	146.00
IUUC-Tni-120706	Tetraodon nigroviridis	59.48	1.00e-39	152.00
IUUC-Tca-121217	Theobroma cacao	80.34	6.00e-46	173.00
IUUC-Tre-122077	Trichoderma reesei	87.07	1.00e-57	212.00
IUUC-Tvi-122400	Trichoderma virens	87.07	1.00e-57	212.00
IUUC-Tae-122697	Triticum aestivum	74.14	3.00e-50	189.00
IUUC-Tur-126158	Triticum urartu	73.28	7.00e-50	187.00
IUUC-Tme-126955	Tuber melanosporum	87.07	1.00e-57	213.00
IUUC-Tbe-127765	Tupaia belangeri	62.79	1.00e-29	119.00
IUUC-Ttr-128205	Tursiops truncatus	60.34	4.00e-40	154.00
IUUC-Vda-129807	Verticillium dahliae	87.07	2.00e-57	212.00
IUUC-Vpa-130804	Vicugna pacos	59.48	9.00e-40	153.00
IUUC-Vvi-130830	Vitis vinifera	79.49	5.00e-46	174.00
IUUC-Xtr-132685	Xenopus tropicalis	60.34	2.00e-40	155.00
IUUC-Xma-133675	Xiphophorus maculatus	59.48	6.00e-40	154.00
IUUC-Yli-134327	Yarrowia lipolytica	82.20	4.00e-48	181.00
IUUC-Zma-135270	Zea mays	80.34	9.00e-53	196.00

Created Date

25-Jun-2017

Functional Description

Protein Fasta Sequence

Nucleotide Fasta Sequence