iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Aml-002192

UUCD1 version

Ensembl Protein ID

UniProt Accession

Genbank Protein ID

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

ACTA01130915

Gene Name

WDR77

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSAMEG00000005454.1	ENSAMET00000006017.1	ENSAMEP00000005776.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	9.30e-18	63.7	169	204

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 2    Htdsvtclaf...sdtllvsGsdDgtikvWDlrtgv 34
           H++ vtc+a     d +++s+s D+ i +WD+r+ +
   Q: 169  HSGQVTCVAAsphKDSMFLSCSEDNRILLWDTRCPK 204
           9*******988765599**************99876 PP

Organism

Ailuropoda melanoleuca

Protein Sequence
(Fasta)

TVEMRKETPP PLVPPAVREW NLPPNAPACM ERQLEAARYR SDGALLLGAS SLSGRCWAGS 60
LWLFKDPCAA PNEGFCSAGV QTEAGVADLT WVGDRGILVA SDSGAVELWE LDENETLIVS 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ACCGTGGAGA TGAGGAAGGA AACCCCGCCC CCCCTAGTGC CCCCGGCGGT CCGCGAGTGG 60
AACCTTCCCC CTAATGCTCC CGCTTGTATG GAACGGCAGT TGGAGGCTGC GCGGTATCGG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0853--WD repeat

Interpro

IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF00400--WD40

SMART

SM00320--WD40

Gene Ontology

GO:0005829--C:cytosol
GO:0005794--C:Golgi apparatus
GO:0034709--C:methylosome
GO:0005654--C:nucleoplasm
GO:0030374--F:ligand-dependent nuclear receptor transcription coactivator activity
GO:0008327--F:methyl-CpG binding
GO:0060770--P:negative regulation of epithelial cell proliferation involved in prostate gland development
GO:0008284--P:positive regulation of cell proliferation
GO:0006357--P:regulation of transcription from RNA polymerase II promoter
GO:0060528--P:secretory columnal luminar epithelial cell differentiation involved in prostate glandular acinus development

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Apl-003921	Anas platyrhynchos	62.30	5.00e-65	239.00
IUUC-Aca-004870	Anolis carolinensis	69.29	4.00e-118	417.00
IUUC-Ame-011872	Astyanax mexicanus	48.63	7.00e-37	146.00
IUUC-Bta-013325	Bos taurus	94.75	0.00e+00	637.00
IUUC-Cja-019059	Callithrix jacchus	92.13	1.00e-179	622.00
IUUC-Cfa-021036	Canis familiaris	95.89	5.00e-163	566.00
IUUC-Cpo-022369	Cavia porcellus	91.25	5.00e-179	619.00
IUUC-Csa-023585	Chlorocebus sabaeus	92.13	3.00e-180	624.00
IUUC-Cho-024470	Choloepus hoffmanni	84.30	7.00e-116	409.00
IUUC-Dno-029867	Dasypus novemcinctus	90.09	6.00e-178	616.00
IUUC-Dor-030834	Dipodomys ordii	63.08	8.00e-112	396.00
IUUC-Dme-031923	Drosophila melanogaster	23.86	2.00e-12	67.00
IUUC-Ete-032245	Echinops telfairi	83.22	6.00e-139	486.00
IUUC-Eca-033360	Equus caballus	92.42	7.00e-174	602.00
IUUC-Eeu-035353	Erinaceus europaeus	90.38	6.00e-177	612.00
IUUC-Fca-036277	Felis catus	96.79	0.00e+00	653.00
IUUC-Fal-037383	Ficedula albicollis	67.83	5.00e-102	363.00
IUUC-Gmo-038575	Gadus morhua	53.57	2.00e-97	348.00
IUUC-Gga-040658	Gallus gallus	70.03	7.00e-129	453.00
IUUC-Gac-041463	Gasterosteus aculeatus	51.68	3.00e-83	301.00
IUUC-Ggo-045120	Gorilla gorilla	91.30	9.00e-180	622.00
IUUC-Hsa-046247	Homo sapiens	91.55	2.00e-179	621.00
IUUC-Itr-048292	Ictidomys tridecemlineatus	91.84	4.00e-175	606.00
IUUC-Lch-049741	Latimeria chalumnae	64.35	1.00e-108	385.00
IUUC-Loc-052695	Lepisosteus oculatus	58.21	2.00e-103	368.00
IUUC-Laf-054535	Loxodonta africana	89.97	2.00e-176	611.00
IUUC-Mcc-054699	Macaca mulatta	92.13	3.00e-180	624.00
IUUC-Meu-056053	Macropus eugenii	77.25	2.00e-136	478.00
IUUC-Mga-059672	Meleagris gallopavo	65.13	7.00e-71	259.00
IUUC-Mmr-060963	Microcebus murinus	94.46	0.00e+00	639.00
IUUC-Mdo-062694	Monodelphis domestica	74.12	6.00e-130	456.00
IUUC-Mmu-064031	Mus musculus	87.46	4.00e-172	597.00
IUUC-Mpu-066408	Mustela putorius furo	97.96	0.00e+00	658.00
IUUC-Mlu-068184	Myotis lucifugus	91.25	9.00e-179	619.00
IUUC-Nle-069251	Nomascus leucogenys	91.84	7.00e-180	622.00
IUUC-Opr-071156	Ochotona princeps	83.09	1.00e-160	559.00
IUUC-Ont-072683	Oreochromis niloticus	56.52	4.00e-95	341.00
IUUC-Oan-073042	Ornithorhynchus anatinus	74.74	1.00e-123	436.00
IUUC-Ocu-074843	Oryctolagus cuniculus	92.71	7.00e-177	612.00
IUUC-Ola-086929	Oryzias latipes	52.78	8.00e-87	313.00
IUUC-Oga-088237	Otolemur garnettii	91.55	3.00e-179	620.00
IUUC-Oar-089312	Ovis aries	94.64	4.00e-168	583.00
IUUC-Ptr-091625	Pan troglodytes	91.55	4.00e-179	620.00
IUUC-Pan-091902	Papio anubis	87.79	2.00e-168	584.00
IUUC-Psi-094035	Pelodiscus sinensis	70.27	7.00e-124	436.00
IUUC-Pma-094565	Petromyzon marinus	64.09	7.00e-58	216.00
IUUC-Pfo-097070	Poecilia formosa	53.99	2.00e-90	325.00
IUUC-Pab-098007	Pongo abelii	91.55	3.00e-179	620.00
IUUC-Pca-100513	Procavia capensis	74.53	1.00e-103	369.00
IUUC-Pva-102821	Pteropus vampyrus	87.17	4.00e-165	573.00
IUUC-Rno-105836	Rattus norvegicus	87.39	1.00e-174	605.00
IUUC-Sha-106847	Sarcophilus harrisii	70.54	6.00e-87	313.00
IUUC-Sar-113451	Sorex araneus	86.34	5.00e-170	590.00
IUUC-Ssc-115978	Sus scrofa	93.59	2.00e-176	611.00
IUUC-Tgu-116745	Taeniopygia guttata	69.00	3.00e-94	337.00
IUUC-Tru-117945	Takifugu rubripes	53.89	3.00e-79	288.00
IUUC-Tsy-119059	Tarsius syrichta	88.20	3.00e-89	320.00
IUUC-Tni-120414	Tetraodon nigroviridis	54.01	1.00e-91	329.00
IUUC-Tbe-127559	Tupaia belangeri	93.88	0.00e+00	634.00
IUUC-Ttr-128505	Tursiops truncatus	91.55	2.00e-176	611.00
IUUC-Vpa-130350	Vicugna pacos	95.63	8.00e-102	362.00
IUUC-Xtr-132939	Xenopus tropicalis	59.52	2.00e-111	395.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence