iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Aml-002003

UUCD1 version

Ensembl Protein ID

UniProt Accession

Genbank Protein ID

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

ACTA01018521

Gene Name

FZR1

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSAMEG00000005634.1	ENSAMET00000006217.1	ENSAMEP00000005970.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/APC_C/CDC20	7.00e-151	501.8	175	479
E3 adaptor/Cullin RING/DCX/DWD	1.30e-26	91.7	311	341

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/APC_C/CDC20

   S: 1    pekvldapelrddfylnLldWssknvlavaLgssvylwsaktgdvskladl.eekdlvtsvswieegtllavGtkkgeveiyDveekkk 88
           p+kvldapel+ddfylnL+dWss nvl+v+Lg++vylwsa+t++v++l+dl  e+d+vtsv w+e+g+l+avGt+kg v+i+D+++ kk
   Q: 175  PFKVLDAPELQDDFYLNLVDWSSLNVLSVGLGTCVYLWSACTSQVTRLCDLsVEGDSVTSVGWSERGNLVAVGTHKGFVQIWDAAAGKK 263
           689************************************************99************************************ PP
   S: 89   vrtltghsarvgaLsWnaevlssGsrdgeilhrdvrvkelkl.stlqahaqevCGlkwnedaklLasGGnDnsvsvwdasssePlkkfk 176
           +++l+gh+arvgaL+Wna++lssGsrd++il+rd+r++ l+  ++lq+h+qevCGlkw++d++lLasGGnDn++ vw++ss +P+++++
   Q: 264  LSMLEGHTARVGALAWNADQLSSGSRDRMILQRDIRTPPLQSeRRLQGHRQEVCGLKWSTDHQLLASGGNDNKLLVWNHSSLSPVQQYT 352
           ******************************************99********************************************* PP
   S: 177  ehkaavkaiawsPwqkslLasGGGtaDrcikfwntltgalleeidtgsqvcsllwskkskelvsthGfaenkitlwkypslskvaelkg 265
           eh aavkaiawsP+q++lLasGGGtaDrci+fwntltg+ l++idtgsqvc+l+wsk+++elvsthG+++n+i +wkypsl++va+l+g
   Q: 353  EHLAAVKAIAWSPHQHGLLASGGGTADRCIRFWNTLTGQPLQCIDTGSQVCNLAWSKHANELVSTHGYSQNQILVWKYPSLTQVAKLTG 441
           ***************************************************************************************** PP
   S: 266  heaRvlslalspdgeaivtaagDetlrfwklfdkkkak 303
           h++Rvl+la+spdgeaivt+agDetlrfw++f+k++++
   Q: 442  HSYRVLYLAMSPDGEAIVTGAGDETLRFWNVFSKTRST 479
           *********************************99875 PP

E3 adaptor/Cullin RING/DCX/DWD

   S: 1    gHtdsvtclaf.sd.tllvsGsdDgtikvWD 29
           gH  +v++l++ +d  ll+sG++D+++ vW+
   Q: 311  GHRQEVCGLKWsTDhQLLASGGNDNKLLVWN 341
           8**********98889**************9 PP

Organism

Ailuropoda melanoleuca

Protein Sequence
(Fasta)

MDQDYERRLL RQIVVQNENT MPCVAEMRRT LTPANSPVSS PSKHGDRFIP SRAGANWSVN 60
FHRINGRGRP GGLPCPFPAL WSPLPTDGLA YSALLKNELL GAGIEKVQDP QTEDRRLQPS 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGGACCAGG ACTATGAGCG GCGCCTCCTC CGGCAGATCG TCGTTCAGAA CGAAAACACA 60
ATGCCCTGTG TGAGTACCTG GCACCCCGCC CCCGCTGGCA CTGCCCTGGC CCCACGCAGG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0677--Repeat
KW-0853--WD repeat

Interpro

IPR024977--Apc4_WD40_dom
IPR033010--Cdc20/Fizzy
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF12894--ANAPC4_WD40
PF00400--WD40

SMART

SM00320--WD40

Gene Ontology

GO:0005680--C:anaphase-promoting complex
GO:0031965--C:nuclear membrane
GO:0005654--C:nucleoplasm
GO:0097027--F:ubiquitin-protein transferase activator activity
GO:0031145--P:anaphase-promoting complex-dependent catabolic process
GO:0031572--P:G2 DNA damage checkpoint
GO:0070306--P:lens fiber cell differentiation
GO:0090344--P:negative regulation of cell aging
GO:0008284--P:positive regulation of cell proliferation
GO:0045732--P:positive regulation of protein catabolic process
GO:1904668--P:positive regulation of ubiquitin protein ligase activity
GO:0040020--P:regulation of meiotic nuclear division

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000670	Aegilops tauschii	63.38	3.00e-114	405.00
IUUC-Atr-002753	Amborella trichopoda	55.46	2.00e-129	456.00
IUUC-Apl-003212	Anas platyrhynchos	93.95	0.00e+00	947.00
IUUC-Aly-005442	Arabidopsis lyrata	54.18	6.00e-137	480.00
IUUC-Ath-006938	Arabidopsis thaliana	55.90	1.00e-134	473.00
IUUC-Ago-007784	Ashbya gossypii	49.28	1.00e-94	340.00
IUUC-Acl-008269	Aspergillus clavatus	49.19	2.00e-131	462.00
IUUC-Afl-008432	Aspergillus flavus	50.00	1.00e-130	460.00
IUUC-Afu-008829	Aspergillus fumigatus	49.80	8.00e-132	464.00
IUUC-Ani-009471	Aspergillus nidulans	49.19	4.00e-130	458.00
IUUC-Ang-009711	Aspergillus niger	49.60	2.00e-129	455.00
IUUC-Aor-010118	Aspergillus oryzae	50.00	1.00e-130	460.00
IUUC-Ate-010534	Aspergillus terreus	49.40	2.00e-130	459.00
IUUC-Ame-011011	Astyanax mexicanus	89.00	0.00e+00	835.00
IUUC-Bgr-012013	Blumeria graminis	50.40	5.00e-130	458.00
IUUC-Bta-012586	Bos taurus	94.96	0.00e+00	956.00
IUUC-Bci-013807	Botrytis cinerea	51.00	2.00e-125	442.00
IUUC-Bdi-014981	Brachypodium distachyon	70.49	2.00e-128	452.00
IUUC-Bol-016301	Brassica oleracea	55.82	6.00e-138	483.00
IUUC-Bra-017453	Brassica rapa	55.82	4.00e-138	484.00
IUUC-Cel-018472	Caenorhabditis elegans	64.99	1.00e-141	496.00
IUUC-Cja-019929	Callithrix jacchus	95.16	0.00e+00	960.00
IUUC-Cfa-020977	Canis familiaris	95.77	0.00e+00	967.00
IUUC-Cpo-021537	Cavia porcellus	94.76	0.00e+00	953.00
IUUC-Csa-023389	Chlorocebus sabaeus	94.35	0.00e+00	947.00
IUUC-Cin-025327	Ciona intestinalis	67.96	9.00e-179	619.00
IUUC-Csv-025921	Ciona savignyi	65.79	0.00e+00	659.00
IUUC-Cgl-026631	Colletotrichum gloeosporioides	50.80	2.00e-130	459.00
IUUC-Cne-026933	Cryptococcus neoformans	59.58	5.00e-127	448.00
IUUC-Cme-027143	Cyanidioschyzon merolae	63.70	5.00e-117	415.00
IUUC-Dre-027470	Danio rerio	87.98	0.00e+00	828.00
IUUC-Dno-029629	Dasypus novemcinctus	96.66	0.00e+00	658.00
IUUC-Dor-030187	Dipodomys ordii	95.85	0.00e+00	805.00
IUUC-Dse-031502	Dothistroma septosporum	49.08	3.00e-125	442.00
IUUC-Dme-031858	Drosophila melanogaster	68.42	0.00e+00	662.00
IUUC-Ete-032562	Echinops telfairi	81.65	0.00e+00	793.00
IUUC-Eca-034210	Equus caballus	94.96	0.00e+00	954.00
IUUC-Fca-035839	Felis catus	89.72	0.00e+00	877.00
IUUC-Fal-036895	Ficedula albicollis	93.95	0.00e+00	948.00
IUUC-Fox-037814	Fusarium oxysporum	64.17	2.00e-122	431.00
IUUC-Fso-038420	Fusarium solani	49.01	5.00e-130	457.00
IUUC-Gmo-039544	Gadus morhua	86.80	0.00e+00	816.00
IUUC-Ggr-039774	Gaeumannomyces graminis	48.77	9.00e-131	460.00
IUUC-Gga-041025	Gallus gallus	93.75	0.00e+00	945.00
IUUC-Gac-041279	Gasterosteus aculeatus	86.55	0.00e+00	873.00
IUUC-Gma-042657	Glycine max	55.65	3.00e-132	465.00
IUUC-Ggo-045599	Gorilla gorilla	94.76	0.00e+00	923.00
IUUC-Hsa-046695	Homo sapiens	94.96	0.00e+00	959.00
IUUC-Hvu-047486	Hordeum vulgare	67.15	4.00e-106	377.00
IUUC-Itr-048192	Ictidomys tridecemlineatus	93.95	0.00e+00	949.00
IUUC-Kpa-049239	Komagataella pastoris	45.96	3.00e-120	425.00
IUUC-Lch-049827	Latimeria chalumnae	92.14	0.00e+00	896.00
IUUC-Lpe-051568	Leersia perrieri	62.86	2.00e-110	392.00
IUUC-Loc-052856	Lepisosteus oculatus	90.76	0.00e+00	879.00
IUUC-Laf-054321	Loxodonta africana	84.00	8.00e-100	357.00
IUUC-Mcc-055601	Macaca mulatta	94.35	0.00e+00	947.00
IUUC-Meu-056276	Macropus eugenii	68.13	9.00e-173	599.00
IUUC-Mor-057113	Magnaporthe oryzae	49.90	4.00e-130	458.00
IUUC-Mpo-057599	Magnaporthe poae	49.05	9.00e-131	460.00
IUUC-Mtr-057689	Medicago truncatula	56.36	2.00e-134	472.00
IUUC-Mla-059048	Melampsora laricipopulina	50.10	2.00e-115	409.00
IUUC-Mga-060097	Meleagris gallopavo	87.80	0.00e+00	873.00
IUUC-Mvi-060465	Microbotryum violaceum	50.30	5.00e-127	447.00
IUUC-Mmr-061151	Microcebus murinus	86.29	0.00e+00	834.00
IUUC-Mdo-063062	Monodelphis domestica	93.55	0.00e+00	945.00
IUUC-Mmu-063731	Mus musculus	94.15	0.00e+00	948.00
IUUC-Mac-064942	Musa acuminata	56.67	1.00e-130	459.00
IUUC-Mpu-066173	Mustela putorius furo	94.76	0.00e+00	951.00
IUUC-Mlu-068030	Myotis lucifugus	95.36	0.00e+00	965.00
IUUC-Nfi-068536	Neosartorya fischeri	50.00	2.00e-132	466.00
IUUC-Ncr-068734	Neurospora crassa	51.63	4.00e-132	464.00
IUUC-Nle-070163	Nomascus leucogenys	94.35	0.00e+00	948.00
IUUC-Opr-070974	Ochotona princeps	91.78	2.00e-154	537.00
IUUC-Ont-072507	Oreochromis niloticus	84.14	0.00e+00	854.00
IUUC-Oan-073634	Ornithorhynchus anatinus	99.66	4.00e-174	603.00
IUUC-Oba-075417	Oryza barthii	64.67	3.00e-110	392.00
IUUC-Obr-076123	Oryza brachyantha	69.51	2.00e-125	442.00
IUUC-Ogl-077294	Oryza glaberrima	70.16	2.00e-125	442.00
IUUC-Ogu-077996	Oryza glumaepatula	69.84	2.00e-124	439.00
IUUC-Oin-080172	Oryza indica	70.16	1.00e-125	442.00
IUUC-Olo-081068	Oryza longistaminata	70.16	2.00e-125	442.00
IUUC-Ome-081250	Oryza meridionalis	70.16	2.00e-125	442.00
IUUC-Oni-083048	Oryza nivara	70.16	2.00e-125	442.00
IUUC-Opu-083333	Oryza punctata	70.16	2.00e-125	442.00
IUUC-Oru-085001	Oryza rufipogon	70.16	2.00e-125	442.00
IUUC-Osa-086243	Oryza sativa	70.16	2.00e-125	442.00
IUUC-Ola-087094	Oryzias latipes	85.07	0.00e+00	795.00
IUUC-Oga-088911	Otolemur garnettii	94.96	0.00e+00	955.00
IUUC-Oar-089508	Ovis aries	94.96	0.00e+00	956.00
IUUC-Ptr-090967	Pan troglodytes	81.22	3.00e-180	624.00
IUUC-Pan-092147	Papio anubis	94.96	0.00e+00	959.00
IUUC-Psi-093702	Pelodiscus sinensis	93.17	0.00e+00	937.00
IUUC-Pma-094581	Petromyzon marinus	80.40	0.00e+00	765.00
IUUC-Pno-095139	Phaeosphaeria nodorum	59.76	1.00e-112	400.00
IUUC-Ppa-095366	Physcomitrella patens	58.14	4.00e-137	481.00
IUUC-Pfo-096309	Poecilia formosa	86.76	0.00e+00	827.00
IUUC-Pab-098762	Pongo abelii	77.82	0.00e+00	738.00
IUUC-Pop-098924	Populus trichocarpa	55.90	9.00e-131	460.00
IUUC-Pca-100565	Procavia capensis	89.22	0.00e+00	848.00
IUUC-Ppe-101924	Prunus persica	56.12	3.00e-134	471.00
IUUC-Pva-102602	Pteropus vampyrus	92.14	0.00e+00	912.00
IUUC-Pgr-103466	Puccinia graminis	51.07	4.00e-115	408.00
IUUC-Ptt-103888	Puccinia triticina	53.71	7.00e-107	381.00
IUUC-Pte-104097	Pyrenophora teres	48.40	2.00e-128	452.00
IUUC-Pyt-104445	Pyrenophora triticirepentis	44.80	7.00e-111	394.00
IUUC-Rno-105028	Rattus norvegicus	93.75	0.00e+00	945.00
IUUC-Sce-106240	Saccharomyces cerevisiae	48.85	2.00e-94	339.00
IUUC-Sha-107107	Sarcophilus harrisii	80.40	0.00e+00	795.00
IUUC-Sja-107900	Schizosaccharomyces japonicus	57.83	3.00e-113	401.00
IUUC-Spo-108056	Schizosaccharomyces pombe	47.86	2.00e-111	395.00
IUUC-Ssl-108391	Sclerotinia sclerotiorum	51.81	4.00e-128	451.00
IUUC-Smo-108878	Selaginella moellendorffii	57.65	8.00e-140	490.00
IUUC-Sit-110563	Setaria italica	69.84	2.00e-120	426.00
IUUC-Sly-111446	Solanum lycopersicum	55.97	4.00e-133	468.00
IUUC-Stu-112491	Solanum tuberosum	55.75	3.00e-132	465.00
IUUC-Sar-112962	Sorex araneus	80.15	7.00e-119	419.00
IUUC-Sbi-114489	Sorghum bicolor	54.55	2.00e-122	432.00
IUUC-Sre-115222	Sporisorium reilianum	58.10	2.00e-130	459.00
IUUC-Ssc-116171	Sus scrofa	94.76	0.00e+00	955.00
IUUC-Tgu-116878	Taeniopygia guttata	82.54	0.00e+00	808.00
IUUC-Tru-118222	Takifugu rubripes	86.76	0.00e+00	831.00
IUUC-Tni-119863	Tetraodon nigroviridis	86.56	0.00e+00	819.00
IUUC-Tca-121599	Theobroma cacao	56.19	9.00e-132	463.00
IUUC-Tre-122249	Trichoderma reesei	50.00	2.00e-130	459.00
IUUC-Tvi-122675	Trichoderma virens	50.10	2.00e-130	459.00
IUUC-Tae-123489	Triticum aestivum	69.84	2.00e-127	449.00
IUUC-Tur-126545	Triticum urartu	60.32	4.00e-103	367.00
IUUC-Tme-127151	Tuber melanosporum	53.71	3.00e-143	501.00
IUUC-Tbe-128056	Tupaia belangeri	89.69	1.00e-167	581.00
IUUC-Ttr-129055	Tursiops truncatus	95.36	0.00e+00	962.00
IUUC-Uma-129555	Ustilago maydis	57.61	6.00e-130	457.00
IUUC-Vda-130027	Verticillium dahliae	49.24	5.00e-132	464.00
IUUC-Vvi-131749	Vitis vinifera	54.09	8.00e-131	460.00
IUUC-Xtr-132808	Xenopus tropicalis	87.90	0.00e+00	887.00
IUUC-Xma-133183	Xiphophorus maculatus	86.76	0.00e+00	827.00
IUUC-Yli-134584	Yarrowia lipolytica	64.10	3.00e-129	455.00
IUUC-Zma-135640	Zea mays	68.04	3.00e-124	438.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence