iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Afu-008845

Ensembl Protein ID

CADAFUAP00004673

UniProt Accession

Q4X1A9; Q4X1A9_ASPFU

Genbank Protein ID

EAL93356.1

Protein Name

Coatomer subunit beta'

Genbank Nucleotide ID

AAHF01000001

Gene Name

AFUA_2G10610

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
CADAFUAG00004673	CADAFUAT00004673	CADAFUAP00004673

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	1.40e-30	103.0	96	129
UBD/Beta-Prp	5.70e-65	218.4	13	295

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 2    Htdsvtclaf.sd.tllvsGsdDgtikvWDlrtg 33
           H d ++++a  ++ ++++++sdD tik+WD+ +g
   Q: 96   HPDYIRSIAVhPTqPFVLTASDDMTIKLWDWEKG 129
           99********9888****************8765 PP

UBD/Beta-Prp

   S: 10   ksvitcvkfspdksllatgsrdgtikvwdvttgkllrslsgheaevtavkfspdgkilvtgseDrtikvwdlstgkcvhtlkghedsvlslsf 102
           +++++ ++f+p +++++t+ ++g + +w++++++ +++++  + +v+a +f+ +++++v gs+D  ++v++++t++ + ++++h d+++s+++
   Q: 13   SERVKGIDFHPTEPWILTTLYSGHVYIWSYESQSIIKTFELTDVPVRAGRFIARKNWIVCGSDDFQLRVYNYNTSEKIASFEAHPDYIRSIAV 105
           678999*************************************************************************************** PP
   S: 103  spsgdklvsGshdrtirvwdletgqcleetlsghdgvvncvvvhpdg.nllvsGslDrtvrlWdlktgkllrtltgghtdsvyslsfdsng.. 192
           +p++ +++++s+d ti++wd+e+g++  ++ +gh++ v++++++p++ n ++s++lDrtv++W+l +     tl+   t+ v+++++ ++   
   Q: 106  HPTQPFVLTASDDMTIKLWDWEKGWKCVQVYEGHSHYVMGLAINPKDtNTFASACLDRTVKIWSLGSPHANFTLEAHETKGVNHVDYYPQAdk 198
           ************************98888***********************************************99********8887777 PP
   S: 193  kelvsgsldgtvklwdlqtgecvrtlnghtdnvksvrfspnderlvsgssDgsiriWdlrsgdllktlqlhnssvisvavlsfgdnvlvlgse 285
           ++l++ s+d+tvk+wd+ t+  + tl+ght+nv+    +p+   ++sgs+Dg+i++W   +  l ++l++  ++ ++va+ + g++ ++ g +
   Q: 199  PYLLTTSDDRTVKVWDYTTKALIATLEGHTSNVSFACYHPELPVIISGSEDGTIKLWHANTYRLEQSLSYGLERAWCVAY-QRGRQGIAMGFD 290
           *******************************************************************************9.666666665555 PP
   S: 286  dskvn 290
           d+ v 
   Q: 291  DGAVV 295
           55544 PP

Organism

Aspergillus fumigatus

Functional Description
(View)

The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin-coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. Coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins.

Protein Sequence
(Fasta)

MRLDVKRQLF ARSERVKGID FHPTEPWILT TLYSGHVYIW SYESQSIIKT FELTDVPVRA 60
GRFIARKNWI VCGSDDFQLR VYNYNTSEKI ASFEAHPDYI RSIAVHPTQP FVLTASDDMT 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGAGATTGG ATGTCAAGGT ACGCAGGCAA GCACTCAGAT GCATATACGT CTACATCCCA 60
TCAGCTCAAA ACTCGGATTG CGATTGCTTG GCTACCCATT GGAATGTTTA CTGATTATTG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0963--Cytoplasm
KW-0968--Cytoplasmic vesicle
KW-0931--ER-Golgi transport
KW-0333--Golgi apparatus
KW-0472--Membrane
KW-0653--Protein transport
KW-1185--Reference proteome
KW-0813--Transport
KW-0853--WD repeat

Interpro

IPR006692--Coatomer_WD-assoc_reg
IPR016453--COPB2
IPR020472--G-protein_beta_WD-40_rep
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR017986--WD40_repeat_dom

PROSITE

PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF04053--Coatomer_WDAD
PF00400--WD40

PRINTS

PR00320--GPROTEINBRPT

SMART

SM00320--WD40

Gene Ontology

GO:0030126--C:COPI vesicle coat
GO:0005829--C:cytosol
GO:0000139--C:Golgi membrane
GO:0005634--C:nucleus
GO:0005198--F:structural molecule activity
GO:0006888--P:ER to Golgi vesicle-mediated transport
GO:0006886--P:intracellular protein transport
GO:0032511--P:late endosome to vacuole transport via multivesicular body sorting pathway
GO:0006890--P:retrograde vesicle-mediated transport, Golgi to ER

KEGG

afm:AFUA_2G10610

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000654	Aegilops tauschii	46.03	0.00e+00	769.00
IUUC-Aml-002154	Ailuropoda melanoleuca	54.80	0.00e+00	978.00
IUUC-Atr-003090	Amborella trichopoda	55.60	0.00e+00	899.00
IUUC-Apl-003976	Anas platyrhynchos	54.17	0.00e+00	975.00
IUUC-Aca-004301	Anolis carolinensis	53.57	0.00e+00	980.00
IUUC-Aly-006508	Arabidopsis lyrata	52.31	0.00e+00	897.00
IUUC-Ath-007630	Arabidopsis thaliana	53.28	0.00e+00	907.00
IUUC-Ago-007914	Ashbya gossypii	49.82	0.00e+00	848.00
IUUC-Acl-008237	Aspergillus clavatus	95.32	0.00e+00	1660.00
IUUC-Afl-008535	Aspergillus flavus	91.60	0.00e+00	1570.00
IUUC-Ani-009135	Aspergillus nidulans	89.94	0.00e+00	1531.00
IUUC-Ang-009654	Aspergillus niger	96.49	0.00e+00	1338.00
IUUC-Aor-009939	Aspergillus oryzae	92.51	0.00e+00	1668.00
IUUC-Ate-010355	Aspergillus terreus	93.62	0.00e+00	1578.00
IUUC-Ame-010922	Astyanax mexicanus	49.94	0.00e+00	853.00
IUUC-Bgr-012249	Blumeria graminis	75.78	0.00e+00	1335.00
IUUC-Bta-013579	Bos taurus	56.62	0.00e+00	893.00
IUUC-Bci-013866	Botrytis cinerea	80.50	0.00e+00	1356.00
IUUC-Bdi-015046	Brachypodium distachyon	52.40	0.00e+00	920.00
IUUC-Bol-015466	Brassica oleracea	52.43	0.00e+00	880.00
IUUC-Bra-016617	Brassica rapa	51.88	0.00e+00	876.00
IUUC-Cel-018387	Caenorhabditis elegans	51.04	0.00e+00	892.00
IUUC-Cja-019145	Callithrix jacchus	54.92	0.00e+00	978.00
IUUC-Cfa-020564	Canis familiaris	54.80	0.00e+00	977.00
IUUC-Cpo-022201	Cavia porcellus	54.92	0.00e+00	979.00
IUUC-Cre-022938	Chlamydomonas reinhardtii	53.78	0.00e+00	864.00
IUUC-Csa-023383	Chlorocebus sabaeus	58.88	0.00e+00	752.00
IUUC-Cho-024454	Choloepus hoffmanni	52.98	0.00e+00	842.00
IUUC-Cin-025681	Ciona intestinalis	51.28	0.00e+00	889.00
IUUC-Csv-026012	Ciona savignyi	52.00	0.00e+00	894.00
IUUC-Cgl-026649	Colletotrichum gloeosporioides	74.11	0.00e+00	1219.00
IUUC-Cne-026986	Cryptococcus neoformans	57.18	0.00e+00	983.00
IUUC-Cme-027219	Cyanidioschyzon merolae	46.63	0.00e+00	796.00
IUUC-Dre-027846	Danio rerio	55.44	0.00e+00	972.00
IUUC-Dor-030462	Dipodomys ordii	54.20	0.00e+00	787.00
IUUC-Dse-031268	Dothistroma septosporum	77.95	0.00e+00	1348.00
IUUC-Dme-031791	Drosophila melanogaster	53.06	0.00e+00	908.00
IUUC-Ete-033166	Echinops telfairi	52.50	0.00e+00	627.00
IUUC-Eca-034180	Equus caballus	53.66	0.00e+00	935.00
IUUC-Eeu-035086	Erinaceus europaeus	44.42	3.00e-104	371.00
IUUC-Fca-036265	Felis catus	54.80	0.00e+00	976.00
IUUC-Fal-037202	Ficedula albicollis	53.51	0.00e+00	930.00
IUUC-Fox-037711	Fusarium oxysporum	78.45	0.00e+00	1261.00
IUUC-Fso-038268	Fusarium solani	78.05	0.00e+00	1248.00
IUUC-Gmo-039046	Gadus morhua	55.32	0.00e+00	967.00
IUUC-Ggr-039863	Gaeumannomyces graminis	79.85	0.00e+00	1314.00
IUUC-Gga-041112	Gallus gallus	54.29	0.00e+00	977.00
IUUC-Gac-041733	Gasterosteus aculeatus	53.91	0.00e+00	946.00
IUUC-Gma-044333	Glycine max	53.17	0.00e+00	922.00
IUUC-Ggo-044984	Gorilla gorilla	54.92	0.00e+00	977.00
IUUC-Hsa-046698	Homo sapiens	54.80	0.00e+00	977.00
IUUC-Hvu-047669	Hordeum vulgare	61.86	2.00e-143	499.00
IUUC-Itr-048212	Ictidomys tridecemlineatus	54.80	0.00e+00	976.00
IUUC-Kpa-049265	Komagataella pastoris	56.90	0.00e+00	980.00
IUUC-Lch-050473	Latimeria chalumnae	55.70	0.00e+00	967.00
IUUC-Lpe-051579	Leersia perrieri	51.46	0.00e+00	911.00
IUUC-Loc-052675	Lepisosteus oculatus	54.21	0.00e+00	971.00
IUUC-Lma-053218	Leptosphaeria maculans	74.73	0.00e+00	1260.00
IUUC-Laf-053757	Loxodonta africana	54.55	0.00e+00	969.00
IUUC-Mcc-054859	Macaca mulatta	54.92	0.00e+00	978.00
IUUC-Meu-056174	Macropus eugenii	44.62	6.00e-91	327.00
IUUC-Mor-057264	Magnaporthe oryzae	79.98	0.00e+00	1296.00
IUUC-Mpo-057538	Magnaporthe poae	79.73	0.00e+00	1335.00
IUUC-Mtr-058310	Medicago truncatula	52.86	0.00e+00	918.00
IUUC-Mla-058937	Melampsora laricipopulina	57.34	0.00e+00	980.00
IUUC-Mga-059875	Meleagris gallopavo	54.04	0.00e+00	972.00
IUUC-Mvi-060240	Microbotryum violaceum	55.22	0.00e+00	994.00
IUUC-Mmr-061261	Microcebus murinus	54.80	0.00e+00	978.00
IUUC-Mdo-062076	Monodelphis domestica	53.88	0.00e+00	981.00
IUUC-Mmu-063324	Mus musculus	54.92	0.00e+00	981.00
IUUC-Mac-064636	Musa acuminata	51.77	0.00e+00	897.00
IUUC-Mpu-065961	Mustela putorius furo	54.80	0.00e+00	977.00
IUUC-Mlu-067059	Myotis lucifugus	54.19	0.00e+00	945.00
IUUC-Nfi-068277	Neosartorya fischeri	98.59	0.00e+00	1681.00
IUUC-Ncr-068659	Neurospora crassa	75.24	0.00e+00	1320.00
IUUC-Nle-069034	Nomascus leucogenys	54.92	0.00e+00	978.00
IUUC-Opr-070334	Ochotona princeps	57.45	0.00e+00	924.00
IUUC-Ont-071563	Oreochromis niloticus	54.91	0.00e+00	970.00
IUUC-Oan-073416	Ornithorhynchus anatinus	56.65	0.00e+00	935.00
IUUC-Ocu-074522	Oryctolagus cuniculus	54.68	0.00e+00	974.00
IUUC-Oba-075760	Oryza barthii	51.73	0.00e+00	890.00
IUUC-Obr-076201	Oryza brachyantha	52.04	0.00e+00	909.00
IUUC-Ogl-077450	Oryza glaberrima	52.33	0.00e+00	914.00
IUUC-Ogu-078994	Oryza glumaepatula	51.73	0.00e+00	889.00
IUUC-Oin-079856	Oryza indica	51.53	0.00e+00	895.00
IUUC-Olo-080731	Oryza longistaminata	52.10	0.00e+00	875.00
IUUC-Ome-081554	Oryza meridionalis	48.48	0.00e+00	833.00
IUUC-Oni-082324	Oryza nivara	51.73	0.00e+00	890.00
IUUC-Opu-083400	Oryza punctata	49.37	0.00e+00	882.00
IUUC-Oru-084829	Oryza rufipogon	51.73	0.00e+00	890.00
IUUC-Osa-086026	Oryza sativa	52.57	0.00e+00	917.00
IUUC-Ola-087245	Oryzias latipes	54.99	0.00e+00	971.00
IUUC-Olu-087655	Ostreococcus lucimarinus	53.12	0.00e+00	910.00
IUUC-Oga-088163	Otolemur garnettii	52.61	0.00e+00	930.00
IUUC-Oar-089842	Ovis aries	54.80	0.00e+00	978.00
IUUC-Ptr-090501	Pan troglodytes	54.92	0.00e+00	978.00
IUUC-Pan-092011	Papio anubis	54.92	0.00e+00	978.00
IUUC-Psi-093308	Pelodiscus sinensis	54.22	0.00e+00	976.00
IUUC-Pma-094695	Petromyzon marinus	54.77	0.00e+00	905.00
IUUC-Pno-094785	Phaeosphaeria nodorum	55.51	0.00e+00	636.00
IUUC-Ppa-095638	Physcomitrella patens	54.30	0.00e+00	931.00
IUUC-Pfo-096587	Poecilia formosa	54.91	0.00e+00	972.00
IUUC-Pab-097926	Pongo abelii	53.08	0.00e+00	899.00
IUUC-Pop-099634	Populus trichocarpa	53.78	0.00e+00	921.00
IUUC-Pca-100965	Procavia capensis	53.58	0.00e+00	939.00
IUUC-Ppe-101470	Prunus persica	52.93	0.00e+00	919.00
IUUC-Pva-102451	Pteropus vampyrus	53.45	0.00e+00	774.00
IUUC-Pgr-103453	Puccinia graminis	59.22	0.00e+00	1017.00
IUUC-Ptt-103868	Puccinia triticina	58.74	0.00e+00	1013.00
IUUC-Pte-104274	Pyrenophora teres	77.05	0.00e+00	1306.00
IUUC-Pyt-104794	Pyrenophora triticirepentis	73.20	0.00e+00	1241.00
IUUC-Rno-105979	Rattus norvegicus	48.98	0.00e+00	739.00
IUUC-Sce-106269	Saccharomyces cerevisiae	50.97	0.00e+00	879.00
IUUC-Sha-106905	Sarcophilus harrisii	55.07	0.00e+00	979.00
IUUC-Sja-107838	Schizosaccharomyces japonicus	53.42	0.00e+00	899.00
IUUC-Spo-108299	Schizosaccharomyces pombe	53.09	0.00e+00	924.00
IUUC-Smo-108828	Selaginella moellendorffii	51.52	0.00e+00	900.00
IUUC-Sit-110239	Setaria italica	51.38	0.00e+00	917.00
IUUC-Sly-111775	Solanum lycopersicum	53.63	0.00e+00	915.00
IUUC-Stu-112906	Solanum tuberosum	52.87	0.00e+00	827.00
IUUC-Sar-113472	Sorex araneus	52.98	0.00e+00	707.00
IUUC-Sbi-113801	Sorghum bicolor	52.05	0.00e+00	919.00
IUUC-Sre-115040	Sporisorium reilianum	57.04	0.00e+00	998.00
IUUC-Ssc-115593	Sus scrofa	54.68	0.00e+00	976.00
IUUC-Tgu-117239	Taeniopygia guttata	54.05	0.00e+00	976.00
IUUC-Tru-118025	Takifugu rubripes	53.31	0.00e+00	966.00
IUUC-Tsy-118824	Tarsius syrichta	52.38	0.00e+00	713.00
IUUC-Tni-120142	Tetraodon nigroviridis	53.61	0.00e+00	964.00
IUUC-Tca-121613	Theobroma cacao	53.28	0.00e+00	922.00
IUUC-Tre-122072	Trichoderma reesei	77.71	0.00e+00	1317.00
IUUC-Tvi-122546	Trichoderma virens	77.28	0.00e+00	1311.00
IUUC-Tae-125488	Triticum aestivum	52.79	0.00e+00	907.00
IUUC-Tur-126283	Triticum urartu	46.27	0.00e+00	768.00
IUUC-Tme-127041	Tuber melanosporum	76.43	0.00e+00	1330.00
IUUC-Tbe-127770	Tupaia belangeri	54.95	0.00e+00	808.00
IUUC-Ttr-129294	Tursiops truncatus	54.68	0.00e+00	973.00
IUUC-Uma-129351	Ustilago maydis	56.51	0.00e+00	999.00
IUUC-Vda-129716	Verticillium dahliae	79.73	0.00e+00	1380.00
IUUC-Vpa-130037	Vicugna pacos	45.75	6.00e-113	400.00
IUUC-Vvi-131689	Vitis vinifera	53.33	0.00e+00	922.00
IUUC-Xtr-132633	Xenopus tropicalis	56.48	0.00e+00	975.00
IUUC-Xma-133347	Xiphophorus maculatus	54.79	0.00e+00	969.00
IUUC-Yli-134455	Yarrowia lipolytica	59.12	0.00e+00	989.00
IUUC-Zma-135867	Zea mays	51.72	0.00e+00	935.00

Created Date

25-Jun-2017

Functional Description

Protein Fasta Sequence

Nucleotide Fasta Sequence